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{
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},
{
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"time": "24hr",
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},
{
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"dose": "8",
"time": "24hr",
"method": "DNA damage 153 induction (GADD153 antibodies) for ER-stress induced apoptosis",
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},
{
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"time": "24hr",
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"species": "rat",
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},
{
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"time": "24hr",
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"species": "rat",
"animal_model": "hepatocytes",
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"result": true
},
{
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"time": "24hr",
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"result": true
},
{
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"time": "24hr",
"method": "cytochrome c release (anti-cytochrome c antibody )",
"species": "rat",
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"result": true
},
{
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"dose": "282",
"time": "24hr",
"method": "cytochrome c release (anti-cytochrome c antibody )",
"species": "rat",
"animal_model": "hepatocytes",
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"result": true
},
{
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"time": "24hr",
"method": "cytochrome c release (anti-cytochrome c antibody )",
"species": "rat",
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"result": true
},
{
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"time": "24hr",
"method": "cytochrome c release (anti-cytochrome c antibody )",
"species": "rat",
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"result": true
},
{
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},
{
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"time": "24hr",
"method": "cytochrome c release (anti-cytochrome c antibody )",
"species": "rat",
"animal_model": "hepatocytes",
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"result": true
},
{
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"compound": "D0115: Sulindac",
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"time": "24hr",
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"species": "rat",
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"result": false
},
{
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"compound": "D1451: Sulindac sulfide",
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"time": "24hr",
"method": "cytochrome c release (anti-cytochrome c antibody )",
"species": "rat",
"animal_model": "hepatocytes",
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"result": true
},
{
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"compound": "D1452: Sulindac sulfone",
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"time": "24hr",
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"species": "rat",
"animal_model": "hepatocytes",
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"result": false
},
{
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"compound": "D0092: Nimesulide",
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"dose": "21",
"time": "24hr",
"method": "cytochrome c release (anti-cytochrome c antibody )",
"species": "rat",
"animal_model": "hepatocytes",
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"result": true
},
{
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"compound": "D0057: Flufenamic Acid",
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"time": "24hr",
"method": "LipidTox, for neutral lipid accumulation, to evaluate lipid content.",
"species": "rat",
"animal_model": "hepatocytes",
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"result": true
},
{
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"method": "LipidTox, for neutral lipid accumulation, to evaluate lipid content.",
"species": "rat",
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"result": true
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{
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"time": "24hr",
"method": "LipidTox, for neutral lipid accumulation, to evaluate lipid content.",
"species": "rat",
"animal_model": "hepatocytes",
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"result": true
},
{
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"compound": "D0079: Meloxicam",
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"dose": "> 500",
"time": "24hr",
"method": "LipidTox, for neutral lipid accumulation, to evaluate lipid content.",
"species": "rat",
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"result": true
},
{
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"time": "24hr",
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"species": "rat",
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{
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"time": "24hr",
"method": "LipidTox, for neutral lipid accumulation, to evaluate lipid content.",
"species": "rat",
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"result": true
},
{
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"compound": "D0010: Acetylsalicylic acid",
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"dose": "NR",
"time": "24hr",
"method": "LipidTox, for neutral lipid accumulation, to evaluate lipid content.",
"species": "rat",
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"result": false
},
{
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"time": "24hr",
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"species": "rat",
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"result": true
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{
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"method": "LipidTox, for neutral lipid accumulation, to evaluate lipid content.",
"species": "rat",
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"result": false
},
{
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"time": "24hr",
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{
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"species": "rat",
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"result": false
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{
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"time": "24hr",
"method": "LipidTox, for neutral lipid accumulation, to evaluate lipid content.",
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"result": true
},
{
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"compound": "D0057: Flufenamic Acid",
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"dose": "129",
"time": "24hr",
"method": "tetramethylrhodamine ethyl ester (TMRE)",
"species": "rat",
"animal_model": "hepatocytes",
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"result": true
},
{
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"compound": "D0122: Tolfenamic Acid",
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"time": "24hr",
"method": "tetramethylrhodamine ethyl ester (TMRE)",
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"criteria": "AC50 (μM)",
"result": true
},
{
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"compound": "D0078: Mefenamic acid",
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"time": "24hr",
"method": "tetramethylrhodamine ethyl ester (TMRE)",
"species": "rat",
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"result": true
},
{
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"dose": "382",
"time": "24hr",
"method": "tetramethylrhodamine ethyl ester (TMRE)",
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"result": true
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{
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"dose": "487",
"time": "24hr",
"method": "tetramethylrhodamine ethyl ester (TMRE)",
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"result": true
}
]
}
