ID Title Authors Journal Publication Year DOI
271. Mechanisms of hepatocellular toxicity associated with dronedarone--a comparison to amiodarone. Felser, Andrea; Blum, Kim; Lindinger, Peter W; Bouitbir, Jamal; Kr?henb?hl, Stephan Toxicological Sciences 2012 10.1093/toxsci/kfs298
36. Prediction of liver injury induced by chemicals in human with a multiparametric assay on isolated mouse liver mitochondria. Porceddu, Mathieu; Buron, Nelly; Roussel, Célestin; Labbe, Gilles; Fromenty, Bernard; Borgne-Sanchez, Annie Toxicological Sciences 2012 10.1093/toxsci/kfs197
174. In vitro assessment of mitochondrial dysfunction and cytotoxicity of nefazodone, trazodone, and buspirone. Dykens, James A; Jamieson, Joseph D; Marroquin, Lisa D; Nadanaciva, Sashi; Xu, Jinghai J; Dunn, Margaret C; Smith, Arthur R; Will, Yvonne Toxicological Sciences 2008 10.1093/toxsci/kfn056
204. The development of structure-activity relationships for mitochondrial dysfunction: uncoupling of oxidative phosphorylation. Naven, Russell T; Swiss, Rachel; Klug-McLeod, Jacquelyn; Will, Yvonne; Greene, Nigel Toxicological Sciences 2013 10.1093/toxsci/kfs279
332. Effects of troglitazone on HepG2 viability and mitochondrial function. Tirmenstein, Mark A; Hu, Catherine X; Gales, Tracy L; Maleeff, Beverly E; Narayanan, Padma K; Kurali, Edit; Hart, Timothy K; Thomas, Heath C; Schwartz, Lester W Toxicological Sciences 2002 10.1093/toxsci/69.1.131
173. Sodium fluoroacetate poisoning. Proudfoot, Alex T; Bradberry, Sally M; Vale, J Allister Toxicological Reviews 1905 10.2165/00139709-200625040-00002
28. Characterization of hepatic mitochondrial injury induced by fatty acid oxidation inhibitors. Vickers, Alison E M Toxicologic Pathology 2009 10.1177/0192623308329285
300. Mitochondrial electron transport chain in heavy metal-induced neurotoxicity: effects of cadmium, mercury, and copper. Belyaeva, Elena A; Sokolova, Tatyana V; Emelyanova, Larisa V; Zakharova, Irina O Thescientificworldjournal 2012 10.1100/2012/136063
211. Mitochondrial Toxicity Associated with Linezolid Soriano, Alex; Mir?, Oscar; Mensa, Josep The New England Journal of Medicine 2005 10.1056/NEJM200511243532123
225. Increased susceptibility to troglitazone-induced mitochondrial permeability transition in type 2 diabetes mellitus model rat. Segawa, Masahiro; Sekine, Shuichi; Sato, Tomoyuki; Ito, Kousei The Journal of toxicological sciences 1905 10.2131/jts.43.339
189. 5-Hydroxydecanoate is metabolised in mitochondria and creates a rate-limiting bottleneck for beta-oxidation of fatty acids. Hanley, Peter J; Dr?se, Stefan; Brandt, Ulrich; Lareau, Rachel A; Banerjee, Abir L; Srivastava, D K; Banaszak, Leonard J; Barycki, Joseph J; Van Veldhoven, Paul P; Daut, J?rgen The Journal of Physiology 2005 10.1113/jphysiol.2004.073932
54. Amineptine, a tricyclic antidepressant, inhibits the mitochondrial oxidation of fatty acids and produces microvesicular steatosis of the liver in mice. Le Dinh, T; Freneaux, E; Labbe, G; Letteron, P; Degott, C; Geneve, J; Berson, A; Larrey, D; Pessayre, D The Journal of Pharmacology and Experimental Therapeutics 1988
110. The pyrethroids permethrin and cyhalothrin are potent inhibitors of the mitochondrial complex I. Gassner, B; Wüthrich, A; Scholtysik, G; Solioz, M The Journal of Pharmacology and Experimental Therapeutics 1997
44. Multiple compound-related adverse properties contribute to liver injury caused by endothelin receptor antagonists. Kenna, J Gerry; Stahl, Simone H; Eakins, Julie A; Foster, Alison J; Andersson, Linda C; Bergare, Jonas; Billger, Martin; Elebring, Marie; Elmore, Charles S; Thompson, Richard A The Journal of Pharmacology and Experimental Therapeutics 2015 10.1124/jpet.114.220491
327. Mitochondrially targeted effects of berberine [Natural Yellow 18, 5,6-dihydro-9,10-dimethoxybenzo(g)-1,3-benzodioxolo(5,6-a) quinolizinium] on K1735-M2 mouse melanoma cells: comparison with direct effects on isolated mitochondrial fractions. Pereira, Gon?alo C; Branco, Ana F; Matos, J?lio A C; Pereira, Sandro L; Parke, Donna; Perkins, Edward L; Serafim, Teresa L; Sard?o, Vilma A; Santos, Maria S; Moreno, Antonio J M; Holy, Jon; Oliveira, Paulo J The Journal of Pharmacology and Experimental Therapeutics 2007 10.1124/jpet.107.128017
209. The anti-inflammatory drug, nimesulide (4-nitro-2-phenoxymethane-sulfoanilide), uncouples mitochondria and induces mitochondrial permeability transition in human hepatoma cells: protection by albumin. Berson, Alain; Cazanave, Sophie; Descatoire, V?ronique; Tinel, Marina; Grodet, Alain; Wolf, Claude; Feldmann, G?rard; Pessayre, Dominique The Journal of Pharmacology and Experimental Therapeutics 2006 10.1124/jpet.106.104125
239. Stereoselective and nonstereoselective effects of ibuprofen enantiomers on mitochondrial beta-oxidation of fatty acids. Freneaux, E; Fromenty, B; Berson, A; Labbe, G; Degott, C; Letteron, P; Larrey, D; Pessayre, D The Journal of Pharmacology and Experimental Therapeutics 1990
27. The kinetic mechanism by which CCCP (carbonyl cyanide m-chlorophenylhydrazone) transports protons across membranes. Kasianowicz, J; Benz, R; McLaughlin, S The Journal of Membrane Biology 1905 10.1007/bf01868942
315. Mitochondrial calcium uptake underlies ROS generation during aminoglycoside-induced hair cell death. Esterberg, Robert; Linbo, Tor; Pickett, Sarah B; Wu, Patricia; Ou, Henry C; Rubel, Edwin W; Raible, David W The Journal of Clinical Investigation 2016 10.1172/JCI84939
264. Targeting mitochondrial biogenesis to overcome drug resistance to MAPK inhibitors Zhang, Gao; Frederick, Dennie T.; Wu, Lawrence; Wei, Zhi; Krepler, Clemens; Srinivasan, Satish; Chae, Young Chan; Xu, Xiaowei; Choi, Harry; Dimwamwa, Elaida; Ope, Omotayo; Shannan, Batool; Basu, Devraj; Zhang, Dongmei; Guha, Manti; Xiao, Min; Randell, Sergio; Sproesser, Katrin; Xu, Wei; Liu, Jephrey; Karakousis, Giorgos C.; Schuchter, Lynn M.; Gangadhar, Tara C.; Amaravadi, Ravi K.; Gu, Mengnan; Xu, Caiyue; Ghosh, Abheek; Xu, Weiting; Tian, Tian; Zhang, Jie; Zha, Shijie; Liu, Qin; Brafford, Patricia; Weeraratna, Ashani; Davies, Michael A.; Wargo, Jennifer A.; Avadhani, Narayan G.; Lu, Yiling; Mills, Gordon B.; Altieri, Dario C.; Flaherty, Keith T.; Herlyn, Meenhard The Journal of Clinical Investigation 2016
74. Crystallographic studies of the Escherichia coli quinol-fumarate reductase with inhibitors bound to the quinol-binding site. Iverson, Tina M; Luna-Chavez, César; Croal, Laura R; Cecchini, Gary; Rees, Douglas C The Journal of Biological Chemistry 2002 10.1074/jbc.M200815200
151. Structural preferences for the binding of chromium nucleotides by beef heart mitochondrial ATPase. Bossard, M J; Schuster, S M The Journal of Biological Chemistry 1981
190. State-dependent inhibition of the mitochondrial KATP channel by glyburide and 5-hydroxydecanoate. Jaborek, M; Yarov-Yarovoy, V; Paucek, P; Garlid, K D The Journal of Biological Chemistry 1998
217. Mitochondrial swelling impairs the transport of organelles in cerebellar granule neurons. Kaasik, Allen; Safiulina, Dzhamilja; Choubey, Vinay; Kuum, Malle; Zharkovsky, Alexander; Veksler, Vladimir The Journal of Biological Chemistry 2007 10.1074/jbc.M702295200
61. Bupivacaine myotoxicity is mediated by mitochondria. Irwin, William; Fontaine, Eric; Agnolucci, Laura; Penzo, Daniele; Betto, Romeo; Bortolotto, Susan; Reggiani, Carlo; Salviati, Giovanni; Bernardi, Paolo The Journal of Biological Chemistry 2002 10.1074/jbc.M108938200
116. Probing the ubiquinone reduction site of mitochondrial complex I using novel cationic inhibitors. Miyoshi, H; Inoue, M; Okamoto, S; Ohshima, M; Sakamoto, K; Iwamura, H The Journal of Biological Chemistry 1997 10.1074/jbc.272.26.16176
134. The mode of inhibition of oxidative phosphorylation by efrapeptin (A23871). Evidence for an alternating site mechanism for ATP synthesis. Cross, R L; Kohlbrenner, W E The Journal of Biological Chemistry 1978
155. Nuclear mutations conferring oligomycin resistance in Neurospora crassa. Edwards, D L; Unger, B W The Journal of Biological Chemistry 1978
156. The relationship between the bovine heart mitochondrial adenosine triphosphatase, lipophilic compounds, and oligomycin. Cunningham, C C; George, D T The Journal of Biological Chemistry 1975
168. Identification of small molecule inhibitors of human cytochrome c oxidase that target chemoresistant glioma cells. Oliva, Claudia R; Markert, Tahireh; Ross, Larry J; White, E Lucile; Rasmussen, Lynn; Zhang, Wei; Everts, Maaike; Moellering, Douglas R; Bailey, Shannon M; Suto, Mark J; Griguer, Corinne E The Journal of Biological Chemistry 2016 10.1074/jbc.M116.749978