ID Title Authors Journal Publication Year DOI
196. Zidovudine induces downregulation of mitochondrial deoxynucleoside kinases: implications for mitochondrial toxicity of antiviral nucleoside analogs. Sun, Ren; Eriksson, Staffan; Wang, Liya Antimicrobial Agents and Chemotherapy 2014 10.1128/AAC.03613-14
171. The oligomycin-sensitivity conferring protein of mitochondrial ATP synthase: emerging new roles in mitochondrial pathophysiology. Antoniel, Manuela; Giorgio, Valentina; Fogolari, Federico; Glick, Gary D; Bernardi, Paolo; Lippe, Giovanna International Journal of Molecular Sciences 2014 10.3390/ijms15057513
52. Mitochondrial dysfunction and electron transport chain complex defect in a rat model of tenofovir disoproxil fumarate nephrotoxicity. Ramamoorthy, Hemalatha; Abraham, Premila; Isaac, Bina Journal of Biochemical and Molecular Toxicology 2014 10.1002/jbt.21560
43. Effects of metformin and other biguanides on oxidative phosphorylation in mitochondria. Bridges, Hannah R; Jones, Andrew J Y; Pollak, Michael N; Hirst, Judy The Biochemical Journal 2014 10.1042/BJ20140620
172. Metformin directly acts on mitochondria to alter cellular bioenergetics. Andrzejewski, Sylvia; Gravel, Simon-Pierre; Pollak, Michael; St-Pierre, Julie Cancer & metabolism 2014 10.1186/2049-3002-2-12
5. The in vitro and in vivo antitumor effects of clotrimazole on oral squamous cell carcinoma. Wang, Juan; Jia, Lihua; Kuang, Zirong; Wu, Tong; Hong, Yun; Chen, Xiaobing; Leung, W Keung; Xia, Juan; Cheng, Bin Plos One 2014 10.1371/journal.pone.0098885
37. Hepatocellular toxicity of benzbromarone: effects on mitochondrial function and structure. Felser, Andrea; Lindinger, Peter W; Schnell, Dominik; Kratschmar, Denise V; Odermatt, Alex; Mies, Suzette; Jenö, Paul; Krähenbühl, Stephan Toxicology 2014 10.1016/j.tox.2014.08.002
175. Strategies to reduce late-stage drug attrition due to mitochondrial toxicity. Dykens, James A; Marroquin, Lisa D; Will, Yvonne Expert Review of Molecular Diagnostics 2014 10.1586/14737159.7.2.161
325. Modulation of mitochondrial bioenergetics in a skeletal muscle cell line model of mitochondrial toxicity. Dott, William; Mistry, Pratibha; Wright, Jayne; Cain, Kelvin; Herbert, Karl E Redox biology 2014 10.1016/j.redox.2013.12.028
162. Novel inhibitors of mitochondrial sn-glycerol 3-phosphate dehydrogenase. Orr, Adam L; Ashok, Deepthi; Sarantos, Melissa R; Ng, Ryan; Shi, Tong; Gerencser, Akos A; Hughes, Robert E; Brand, Martin D Plos One 2014 10.1371/journal.pone.0089938
21. Pioglitazone leads to an inactivation and disassembly of complex I of the mitochondrial respiratory chain. García-Ruiz, Inmaculada; Solís-Muñoz, Pablo; Fernández-Moreira, Daniel; Muñoz-Yagüe, Teresa; Solís-Herruzo, José A BMC Biology 2013 10.1186/1741-7007-11-88
40. Toxicity assessments of nonsteroidal anti-inflammatory drugs in isolated mitochondria, rat hepatocytes, and zebrafish show good concordance across chemical classes. Nadanaciva, Sashi; Aleo, Michael D; Strock, Christopher J; Stedman, Donald B; Wang, Huijun; Will, Yvonne Toxicology and Applied Pharmacology 2013 10.1016/j.taap.2013.06.019
260. Novel small-molecule PGC-1alpha transcriptional regulator with beneficial effects on diabetic db/db mice. Zhang, Li-Na; Zhou, Hua-Yong; Fu, Yan-Yun; Li, Yuan-Yuan; Wu, Fang; Gu, Min; Wu, Ling-Yan; Xia, Chun-Mei; Dong, Tian-Cheng; Li, Jing-Ya; Shen, Jing-Kang; Li, Jia Diabetes 2013 10.2337/db12-0703
310. A novel Drp1 inhibitor diminishes aberrant mitochondrial fission and neurotoxicity. Qi, Xin; Qvit, Nir; Su, Yu-Chin; Mochly-Rosen, Daria Journal of Cell Science 2013 10.1242/jcs.114439
227. Drug-Induced Inhibition of Mitochondrial Fatty Acid Oxidation and Steatosis Massart, Julie; Begriche, Karima; Buron, Nelly; Porceddu, Mathieu; Borgne-Sanchez, Annie; Fromenty, Bernard Current pathobiology reports 2013 10.1007/s40139-013-0022-y
34. Thiazolidinediones are acute, specific inhibitors of the mitochondrial pyruvate carrier. Divakaruni, Ajit S; Wiley, Sandra E; Rogers, George W; Andreyev, Alexander Y; Petrosyan, Susanna; Loviscach, Mattias; Wall, Estelle A; Yadava, Nagendra; Heuck, Alejandro P; Ferrick, David A; Henry, Robert R; McDonald, William G; Colca, Jerry R; Simon, Melvin I; Ciaraldi, Theodore P; Murphy, Anne N Proceedings of the National Academy of Sciences of the United States of America 2013 10.1073/pnas.1303360110
204. The development of structure-activity relationships for mitochondrial dysfunction: uncoupling of oxidative phosphorylation. Naven, Russell T; Swiss, Rachel; Klug-McLeod, Jacquelyn; Will, Yvonne; Greene, Nigel Toxicological Sciences 2013 10.1093/toxsci/kfs279
86. Comparative developmental toxicity of environmentally relevant oxygenated PAHs. Knecht, Andrea L; Goodale, Britton C; Truong, Lisa; Simonich, Michael T; Swanson, Annika J; Matzke, Melissa M; Anderson, Kim A; Waters, Katrina M; Tanguay, Robert L Toxicology and Applied Pharmacology 2013 10.1016/j.taap.2013.05.006
48. Mitochondrial dysfunction induced by sertraline, an antidepressant agent. Li, Yan; Couch, Letha; Higuchi, Masahiro; Fang, Jia-Long; Guo, Lei Toxicological Sciences 2012 10.1093/toxsci/kfs100
271. Mechanisms of hepatocellular toxicity associated with dronedarone--a comparison to amiodarone. Felser, Andrea; Blum, Kim; Lindinger, Peter W; Bouitbir, Jamal; Kr?henb?hl, Stephan Toxicological Sciences 2012 10.1093/toxsci/kfs298
36. Prediction of liver injury induced by chemicals in human with a multiparametric assay on isolated mouse liver mitochondria. Porceddu, Mathieu; Buron, Nelly; Roussel, Célestin; Labbe, Gilles; Fromenty, Bernard; Borgne-Sanchez, Annie Toxicological Sciences 2012 10.1093/toxsci/kfs197
1. Acetaminophen-induced liver injury in rats and mice: comparison of protein adducts, mitochondrial dysfunction, and oxidative stress in the mechanism of toxicity. McGill, Mitchell R; Williams, C David; Xie, Yuchao; Ramachandran, Anup; Jaeschke, Hartmut Toxicology and Applied Pharmacology 2012 10.1016/j.taap.2012.08.015
300. Mitochondrial electron transport chain in heavy metal-induced neurotoxicity: effects of cadmium, mercury, and copper. Belyaeva, Elena A; Sokolova, Tatyana V; Emelyanova, Larisa V; Zakharova, Irina O Thescientificworldjournal 2012 10.1100/2012/136063
60. In vitro inhibition of mitochondrial respiratory rate by antidepressants. Hroudová, Jana; Fišar, Zdeněk Toxicology Letters 2012 10.1016/j.toxlet.2012.07.017
7. Assessment of drug-induced mitochondrial dysfunction via altered cellular respiration and acidification measured in a 96-well platform. Nadanaciva, Sashi; Rana, Payal; Beeson, Gyda C; Chen, Denise; Ferrick, David A; Beeson, Craig C; Will, Yvonne Journal of Bioenergetics and Biomembranes 2012 10.1007/s10863-012-9446-z
312. Gentamicin rapidly inhibits mitochondrial metabolism in high-frequency cochlear outer hair cells. Jensen-Smith, Heather C; Hallworth, Richard; Nichols, Michael G Plos One 2012 10.1371/journal.pone.0038471
26. Mitochondrial electron transport chain complex III is required for antimycin A to inhibit autophagy. Ma, Xiuquan; Jin, Mingzhi; Cai, Yu; Xia, Hongguang; Long, Kai; Liu, Junli; Yu, Qiang; Yuan, Junying Chemistry & Biology 2011 10.1016/j.chembiol.2011.08.009
2. Acetylsalicylic acid-induced oxidative stress, cell cycle arrest, apoptosis and mitochondrial dysfunction in human hepatoma HepG2 cells. Raza, Haider; John, Annie; Benedict, Sheela European Journal of Pharmacology 2011 10.1016/j.ejphar.2011.06.016
24. 2,4-dinitrophenol (DNP): a weight loss agent with significant acute toxicity and risk of death. Grundlingh, Johann; Dargan, Paul I; El-Zanfaly, Marwa; Wood, David M Journal of Medical Toxicology 2011 10.1007/s13181-011-0162-6
50. Mitochondrial membrane potential measurement of H9c2 cells grown in high-glucose and galactose-containing media does not provide additional predictivity towards mitochondrial assessment. Rana, Payal; Nadanaciva, Sashi; Will, Yvonne Toxicology in Vitro 2011 10.1016/j.tiv.2010.11.016