| 3. |
Target identification of drug induced mitochondrial toxicity using immunocapture based OXPHOS activity assays. |
Nadanaciva, Sashi; Bernal, Autumn; Aggeler, Robert; Capaldi, Roderick; Will, Yvonne |
Toxicology in Vitro |
2007 |
10.1016/j.tiv.2007.01.011 |
| 249. |
Glycolysis inhibition for anticancer treatment. |
Pelicano, H; Martin, D S; Xu, R-H; Huang, P |
Oncogene |
2006 |
10.1038/sj.onc.1209597 |
| 281. |
Inhibition of mammalian mitochondrial protein synthesis by oxazolidinones. |
McKee, E E; Ferguson, M; Bentley, A T; Marks, T A |
Antimicrobial Agents and Chemotherapy |
2006 |
10.1128/AAC.01411-05 |
| 20. |
Effect of the anti-anginal agent, perhexiline, on neutrophil, valvular and vascular superoxide formation. |
Kennedy, Jennifer A; Beck-Oldach, Konstanz; McFadden-Lewis, Kate; Murphy, Geraldine A; Wong, Yee W; Zhang, Yi; Horowitz, John D |
European Journal of Pharmacology |
2006 |
10.1016/j.ejphar.2005.11.058 |
| 229. |
Mitochondrial thioredoxin in regulation of oxidant-induced cell death. |
Chen, Yan; Cai, Jiyang; Jones, Dean P |
FEBS Letters |
2006 |
10.1016/j.febslet.2006.11.007 |
| 41. |
Bioactivation and hepatotoxicity of nitroaromatic drugs. |
Boelsterli, Urs A; Ho, Han Kiat; Zhou, Shufeng; Leow, Koon Yeow |
Current Drug Metabolism |
2006 |
10.2174/138920006778520606 |
| 10. |
Mefloquine selectively increases asynchronous acetylcholine release from motor nerve terminals. |
McArdle, Joseph J; Sellin, Lawrence C; Coakley, Kathleen M; Potian, Joseph G; Hognason, Kormakur |
Neuropharmacology |
2006 |
10.1016/j.neuropharm.2005.09.011 |
| 72. |
Structural and computational analysis of the quinone-binding site of complex II (succinate-ubiquinone oxidoreductase): a mechanism of electron transfer and proton conduction during ubiquinone reduction. |
Horsefield, Rob; Yankovskaya, Victoria; Sexton, Graham; Whittingham, William; Shiomi, Kazuro; Omura, Satoshi; Byrne, Bernadette; Cecchini, Gary; Iwata, So |
The Journal of Biological Chemistry |
2006 |
10.1074/jbc.M508173200 |
| 331. |
Mitochondrial permeability transition as a potential determinant of hepatotoxicity of antidiabetic thiazolidinediones. |
Masubuchi, Yasuhiro; Kano, Satomi; Horie, Toshiharu |
Toxicology |
2006 |
10.1016/j.tox.2006.02.017 |
| 209. |
The anti-inflammatory drug, nimesulide (4-nitro-2-phenoxymethane-sulfoanilide), uncouples mitochondria and induces mitochondrial permeability transition in human hepatoma cells: protection by albumin. |
Berson, Alain; Cazanave, Sophie; Descatoire, V?ronique; Tinel, Marina; Grodet, Alain; Wolf, Claude; Feldmann, G?rard; Pessayre, Dominique |
The Journal of Pharmacology and Experimental Therapeutics |
2006 |
10.1124/jpet.106.104125 |
| 211. |
Mitochondrial Toxicity Associated with Linezolid |
Soriano, Alex; Mir?, Oscar; Mensa, Josep |
The New England Journal of Medicine |
2005 |
10.1056/NEJM200511243532123 |
| 289. |
Inhibition of MG132-induced mitochondrial dysfunction and cell death in PC12 cells by 3-morpholinosydnonimine. |
Lee, Chung Soo; Han, Eun Sook; Park, Eon Sob; Bang, Hyoweon |
Brain Research |
2005 |
10.1016/j.brainres.2004.12.036 |
| 4. |
Mechanisms of benzarone and benzbromarone-induced hepatic toxicity. |
Kaufmann, Priska; Török, Michael; Hänni, Anya; Roberts, Paul; Gasser, Rodolfo; Krähenbühl, Stephan |
Hepatology |
2005 |
10.1002/hep.20634 |
| 282. |
Oxazolidinones inhibit cellular proliferation via inhibition of mitochondrial protein synthesis. |
Nagiec, Eva E; Wu, Luping; Swaney, Steve M; Chosay, John G; Ross, Daniel E; Brieland, Joan K; Leach, Karen L |
Antimicrobial Agents and Chemotherapy |
2005 |
10.1128/AAC.49.9.3896-3902.2005 |
| 82. |
Mechanistic differences in inhibition of ubiquinol cytochrome c reductase by the proximal Qo-site inhibitors famoxadone and methoxyacrylate stilbene. |
Pember, Stephen O; Fleck, Lois C; Moberg, William K; Walker, Michael P |
Archives of Biochemistry and Biophysics |
2005 |
10.1016/j.abb.2004.12.013 |
| 57. |
Release of cytochrome c from isolated mitochondria by etoposide. |
Park, Jung-Hee; Kim, Tae-Hyoung |
Journal of Biochemistry and Molecular Biology |
2005 |
10.5483/bmbrep.2005.38.5.619 |
| 70. |
A possible site of superoxide generation in the complex I segment of rat heart mitochondria. |
Ohnishi, S Tsuyoshi; Ohnishi, Tomoko; Muranaka, Shikibu; Fujita, Hirofumi; Kimura, Hiroko; Uemura, Koichi; Yoshida, Ken-ichi; Utsumi, Kozo |
Journal of Bioenergetics and Biomembranes |
2005 |
10.1007/s10863-005-4117-y |
| 142. |
Inhibition sites in F1-ATPase from bovine heart mitochondria. |
Gledhill, Jonathan R; Walker, John E |
The Biochemical Journal |
2005 |
10.1042/BJ20041513 |
| 185. |
Drug-induced mitochondrial toxicity. |
Chan, Katie; Truong, Don; Shangari, Nandita; O'Brien, Peter J |
Expert Opinion on Drug Metabolism & Toxicology |
2005 |
10.1517/17425255.1.4.655 |
| 189. |
5-Hydroxydecanoate is metabolised in mitochondria and creates a rate-limiting bottleneck for beta-oxidation of fatty acids. |
Hanley, Peter J; Dr?se, Stefan; Brandt, Ulrich; Lareau, Rachel A; Banerjee, Abir L; Srivastava, D K; Banaszak, Leonard J; Barycki, Joseph J; Van Veldhoven, Paul P; Daut, J?rgen |
The Journal of Physiology |
2005 |
10.1113/jphysiol.2004.073932 |
| 330. |
Troglitazone induces a rapid drop of mitochondrial membrane potential in liver HepG2 cells. |
Bova, Michael P; Tam, Danny; McMahon, Gerald; Mattson, Matthew N |
Toxicology Letters |
2005 |
10.1016/j.toxlet.2004.08.009 |
| 262. |
Oxaliplatin, a potent inhibitor of survivin, enhances paclitaxel-induced apoptosis and mitotic catastrophe in colon cancer cells. |
Fujie, Yujiro; Yamamoto, Hirofumi; Ngan, Chew Yee; Takagi, Akimitsu; Hayashi, Taro; Suzuki, Rei; Ezumi, Koji; Takemasa, Ichiro; Ikeda, Masataka; Sekimoto, Mitsugu; Matsuura, Nariaki; Monden, Morito |
Japanese journal of clinical oncology |
2005 |
10.1093/jjco/hyi130 |
| 258. |
Acetaminophen induced hepatotoxicity: role of metabolic activation, reactive oxygen/nitrogen species, and mitochondrial permeability transition |
Hinson, Jack A.; Reid, Angela B.; McCullough, Sandra S.; James, Laura P. |
Drug Metabolism Reviews |
2004 |
10.1081/DMR-200033494 |
| 17. |
Metabolic manipulation in ischaemic heart disease, a novel approach to treatment. |
Lee, Leong; Horowitz, John; Frenneaux, Michael |
European Heart Journal |
2004 |
10.1016/j.ehj.2004.02.018 |
| 83. |
Crystallographic studies of quinol oxidation site inhibitors: a modified classification of inhibitors for the cytochrome bc(1) complex. |
Esser, Lothar; Quinn, Byron; Li, Yong-Fu; Zhang, Minquan; Elberry, Maria; Yu, Linda; Yu, Chang-An; Xia, Di |
Journal of Molecular Biology |
2004 |
10.1016/j.jmb.2004.05.065 |
| 285. |
Human mitochondrial complex I assembles through the combination of evolutionary conserved modules: a framework to interpret complex I deficiencies. |
Ugalde, Cristina; Vogel, Rutger; Huijbens, Richard; Van Den Heuvel, Bert; Smeitink, Jan; Nijtmans, Leo |
Human Molecular Genetics |
2004 |
10.1093/hmg/ddh262 |
| 219. |
Axonal mitochondrial transport and potential are correlated. |
Miller, Kyle E; Sheetz, Michael P |
Journal of Cell Science |
2004 |
10.1242/jcs.01130 |
| 47. |
Measurement of oxygen consumption in mouse aortic endothelial cells using a microparticulate oximetry probe. |
Pandian, Ramasamy P; Kutala, Vijay Kumar; Parinandi, Narasimham L; Zweier, Jay L; Kuppusamy, Periannan |
Archives of Biochemistry and Biophysics |
2003 |
10.1016/j.abb.2003.09.008 |
| 23. |
Differential effects of typical and atypical neuroleptics on mitochondrial function in vitro. |
Modica-Napolitano, Josephine S; Lagace, Christopher J; Brennan, William A; Aprille, June R |
Archives of Pharmacal Research |
2003 |
10.1007/bf02980205 |
| 68. |
Tacrolimus and sirolimus decrease oxidative phosphorylation of isolated rat kidney mitochondria. |
Simon, Nicolas; Morin, Christophe; Urien, Saïk; Tillement, Jean-Paul; Bruguerolle, Bernard |
British Journal of Pharmacology |
2003 |
10.1038/sj.bjp.0705038 |
