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"animal_model": "human umbilical vein endothelial cell, nonmitochondrial ATP synthase, ATP synthesis",
"criteria": "",
"result": true
},
{
"rec_id": "RC01433",
"func": "F020103",
"targ": "T019",
"compound": "D0172: Diethylstilbestrol",
"paper": "143",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "10 μM",
"time": "",
"method": "",
"species": "rat",
"animal_model": "liver MF0F1-ATPase",
"criteria": "",
"result": true
},
{
"rec_id": "RC01434",
"func": "F020103",
"targ": "T019",
"compound": "D0172: Diethylstilbestrol",
"paper": "141",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "10-25 μM",
"time": "",
"method": "",
"species": "rat",
"animal_model": "brain MF0F1-ATPase",
"criteria": "",
"result": true
},
{
"rec_id": "RC01435",
"func": "F020103",
"targ": "T019",
"compound": "D1262: SITS",
"paper": "144",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "∼1.3 μM",
"time": "",
"method": "",
"species": "V. parahaemolyticus",
"animal_model": "F0F1-ATPase",
"criteria": "",
"result": true
},
{
"rec_id": "RC01436",
"func": "F020103",
"targ": "T019",
"compound": "D1262: SITS",
"paper": "145",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "25 μM",
"time": "",
"method": "",
"species": "V. parahaemolyticus",
"animal_model": "F1-ATPase",
"criteria": "95% inhibition",
"result": true
},
{
"rec_id": "RC01437",
"func": "F020103",
"targ": "T019",
"compound": "D1263: DIDS",
"paper": "146",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "20.9 μM",
"time": "",
"method": "",
"species": "rat",
"animal_model": "liver MF1ATPase",
"criteria": "",
"result": true
},
{
"rec_id": "RC01438",
"func": "F020103",
"targ": "T019",
"compound": "D1077: quercetin",
"paper": "147",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "5 kmol/mol",
"time": "",
"method": "",
"species": "bovine",
"animal_model": "heart MF1-ATPase",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01439",
"func": "F020103",
"targ": "T019",
"compound": "D1077: quercetin",
"paper": "148",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "85 μM",
"time": "",
"method": "",
"species": "bovine",
"animal_model": "heart MF1-ATPase",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01440",
"func": "F020103",
"targ": "T019",
"compound": "D1077: quercetin",
"paper": "148",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "180 μM",
"time": "",
"method": "",
"species": "bovine",
"animal_model": "heart SMP-ATPase",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01441",
"func": "F020103",
"targ": "T019",
"compound": "D1077: quercetin",
"paper": "140",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "50 μM",
"time": "",
"method": "",
"species": "rat",
"animal_model": "brain F0F1-ATPase",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01442",
"func": "F020103",
"targ": "T019",
"compound": "D1077: quercetin",
"paper": "141",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "3 μM",
"time": "",
"method": "",
"species": "rat",
"animal_model": "liver F1-ATPase",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01443",
"func": "F020103",
"targ": "T019",
"compound": "D1077: quercetin",
"paper": "147",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "2 kmol/mola",
"time": "",
"method": "",
"species": "spinach",
"animal_model": "CF1-ATPase",
"criteria": "",
"result": true
},
{
"rec_id": "RC01444",
"func": "F020103",
"targ": "T019",
"compound": "D1077: quercetin",
"paper": "131",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "2.6 μg/mg protein",
"time": "",
"method": "",
"species": "C. asciculate",
"animal_model": "SMP-ATPase",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01445",
"func": "F020103",
"targ": "T019",
"compound": "D1077: quercetin",
"paper": "149",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "0.2 mM",
"time": "",
"method": "",
"species": "pig",
"animal_model": "heart MF1-ATPase",
"criteria": "Ki",
"result": true
},
{
"rec_id": "RC01446",
"func": "F020103",
"targ": "T019",
"compound": "D1077: quercetin",
"paper": "147",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "27 μM",
"time": "",
"method": "",
"species": "bovine",
"animal_model": "heart MF1-ATPase",
"criteria": "Kd",
"result": true
},
{
"rec_id": "RC01447",
"func": "F020103",
"targ": "T019",
"compound": "D1077: quercetin",
"paper": "150",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "5 μM",
"time": "",
"method": "",
"species": "C. thermoaceticum",
"animal_model": "membrane-bound F0F1-ATPase",
"criteria": "46% inhibition",
"result": true
},
{
"rec_id": "RC01448",
"func": "F020103",
"targ": "T019",
"compound": "D0969: kaempferol",
"paper": "140",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "55 μM",
"time": "",
"method": "",
"species": "rat",
"animal_model": "brain MF0F1-ATPase",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01449",
"func": "F020103",
"targ": "T019",
"compound": "D1264: morin",
"paper": "140",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "60 μM ",
"time": "",
"method": "",
"species": "rat",
"animal_model": "brain MF0F1-ATPase",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01450",
"func": "F020103",
"targ": "T019",
"compound": "D0781: apigenin",
"paper": "140",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "105 μM ",
"time": "",
"method": "",
"species": "rat",
"animal_model": "brain MF0F1-ATPase",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01451",
"func": "F020103",
"targ": "T019",
"compound": "D0951: genistein",
"paper": "140",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "55 μM",
"time": "",
"method": "",
"species": "rat",
"animal_model": "brain MF0F1-ATPase",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01452",
"func": "F020103",
"targ": "T019",
"compound": "D0951: genistein",
"paper": "141",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "50 μM",
"time": "",
"method": "",
"species": "rat",
"animal_model": "liver F1-ATPase",
"criteria": "10% inhibition",
"result": true
},
{
"rec_id": "RC01453",
"func": "F020103",
"targ": "T019",
"compound": "D0263: Biochanin A",
"paper": "140",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "65 μM ",
"time": "",
"method": "",
"species": "rat",
"animal_model": "brain MF0F1-ATPase",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01454",
"func": "F020103",
"targ": "T019",
"compound": "D0139: Daidzein",
"paper": "151",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "127 μM ",
"time": "",
"method": "",
"species": "rat",
"animal_model": "brain MF0F1-ATPase",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01455",
"func": "F020103",
"targ": "T019",
"compound": "D0289: Oligomycin",
"paper": "152",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "152 μg inhibitor/mg protein",
"time": "",
"method": "",
"species": "E. coli",
"animal_model": "membrane vesicle",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01456",
"func": "F020103",
"targ": "T019",
"compound": "D0289: Oligomycin",
"paper": "131",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "7.1 μg inhibitor/mg protein",
"time": "",
"method": "",
"species": "C. asciculate",
"animal_model": "SMP-ATPase",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01457",
"func": "F020103",
"targ": "T019",
"compound": "D0289: Oligomycin",
"paper": "153",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "2.0-3.0 μg inhibitor/mg protein",
"time": "",
"method": "",
"species": "S. cerevisiae",
"animal_model": "SMP-ATPase",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01458",
"func": "F020103",
"targ": "T019",
"compound": "D0289: Oligomycin",
"paper": "154",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "0.3 μM ",
"time": "",
"method": "",
"species": "human",
"animal_model": "NCI-60 cell lines, F0F1-ATPase",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01459",
"func": "F020103",
"targ": "T019",
"compound": "D0289: Oligomycin",
"paper": "155",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "15 ng inhibitor/mg protein",
"time": "",
"method": "",
"species": "N. crassa",
"animal_model": "SMP-ATPase",
"criteria": "Ki",
"result": true
},
{
"rec_id": "RC01460",
"func": "F020103",
"targ": "T019",
"compound": "D0289: Oligomycin",
"paper": "156",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "0.21 μM",
"time": "",
"method": "",
"species": "bovine",
"animal_model": "heart MF0F1-ATPase",
"criteria": "Ki",
"result": true
},
{
"rec_id": "RC01461",
"func": "F020103",
"targ": "T019",
"compound": "D0289: Oligomycin",
"paper": "157",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "0.4 μg inhibitor/mg protein",
"time": "",
"method": "",
"species": "bovine",
"animal_model": "heart SMP-ATPase",
"criteria": "95% inhibition",
"result": true
},
{
"rec_id": "RC01462",
"func": "F020103",
"targ": "T019",
"compound": "D0289: Oligomycin",
"paper": "158",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "0.5 μg/ml ",
"time": "",
"method": "",
"species": "rat",
"animal_model": "liver SMP-ATPase",
"criteria": "75% inhibition",
"result": true
},
{
"rec_id": "RC01463",
"func": "F020103",
"targ": "T019",
"compound": "D1265: peliomycin",
"paper": "153",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "4.5 μg inhibitor/mg protein",
"time": "",
"method": "",
"species": "S. cerevisiae",
"animal_model": "SMP-ATPase",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01464",
"func": "F020103",
"targ": "T019",
"compound": "D0563: venturicidin B",
"paper": "152",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "9 μg inhibitor/mg protein",
"time": "",
"method": "",
"species": "E. coli",
"animal_model": "membrane vesicle",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01465",
"func": "F020103",
"targ": "T019",
"compound": "D0563: venturicidin B",
"paper": "152",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "11 μg inhibitor/mg protein",
"time": "",
"method": "",
"species": "E. coli",
"animal_model": "membrane-bound ATPase",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01466",
"func": "F020103",
"targ": "T019",
"compound": "D0563: venturicidin B",
"paper": "153",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "0.13 μg inhibitor/mg protein",
"time": "",
"method": "",
"species": "",
"animal_model": "",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01467",
"func": "F020103",
"targ": "T019",
"compound": "D0563: venturicidin B",
"paper": "159",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "0.06-0.18 (A and B) and 11.0 (X) μg inhibitor/mg protein",
"time": "",
"method": "",
"species": "S. cerevisiae",
"animal_model": "SMP-ATPase",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01468",
"func": "F020103",
"targ": "T019",
"compound": "D0563: venturicidin B",
"paper": "138",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "5-11 μg inhibitor/mg protein",
"time": "",
"method": "",
"species": "T. pyriformis",
"animal_model": "",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01469",
"func": "F020103",
"targ": "T019",
"compound": "D0563: venturicidin B",
"paper": "131",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "3.0 μg/mg protein",
"time": "",
"method": "",
"species": "C. asciculate",
"animal_model": "SMP-ATPase",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01470",
"func": "F020103",
"targ": "T019",
"compound": "D0563: venturicidin B",
"paper": "160",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "0.5 μM",
"time": "",
"method": "",
"species": "spinach",
"animal_model": "thylakoids",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01471",
"func": "F020103",
"targ": "T019",
"compound": "D0563: venturicidin B",
"paper": "160",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "0.5 μM",
"time": "",
"method": "",
"species": "spinach",
"animal_model": "thylakoids, ATPase",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01472",
"func": "F020103",
"targ": "T019",
"compound": "D0562: ossamycin",
"paper": "153",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "1.3 μg of inhibitor/mg protein",
"time": "",
"method": "",
"species": "S. cerevisiae",
"animal_model": "SMP-ATPase",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01473",
"func": "F020103",
"targ": "T019",
"compound": "D0562: ossamycin",
"paper": "152",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "46 μg of inhibitor/mg protein",
"time": "",
"method": "",
"species": "E. coli",
"animal_model": "membrane vesicle",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01474",
"func": "F020103",
"targ": "T019",
"compound": "D0562: ossamycin",
"paper": "154",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "8 μM",
"time": "",
"method": "",
"species": "human",
"animal_model": "NCI-60 cell lines, F0F1-ATPase",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01475",
"func": "F020103",
"targ": "T019",
"compound": "D1266: apoptolidin",
"paper": "161",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "4-5 μM",
"time": "",
"method": "",
"species": "S. cerevisiae",
"animal_model": "membrane-bound F0F1-ATPase",
"criteria": "Ki",
"result": true
},
{
"rec_id": "RC01476",
"func": "F020103",
"targ": "T019",
"compound": "D1266: apoptolidin",
"paper": "154",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "18 μM",
"time": "",
"method": "",
"species": "human",
"animal_model": "NCI-60 cell lines, F0F1-ATPase",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01477",
"func": "F020103",
"targ": "T019",
"compound": "D1267: cytovaricin",
"paper": "154",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "1 μM",
"time": "",
"method": "",
"species": "human",
"animal_model": "NCI-60 cell lines, F0F1-ATPase",
"criteria": "IC50",
"result": true
}
]
}
