ID Title Authors Journal Publication Year DOI
1. Acetaminophen-induced liver injury in rats and mice: comparison of protein adducts, mitochondrial dysfunction, and oxidative stress in the mechanism of toxicity. McGill, Mitchell R; Williams, C David; Xie, Yuchao; Ramachandran, Anup; Jaeschke, Hartmut Toxicology and Applied Pharmacology 2012 10.1016/j.taap.2012.08.015
2. Acetylsalicylic acid-induced oxidative stress, cell cycle arrest, apoptosis and mitochondrial dysfunction in human hepatoma HepG2 cells. Raza, Haider; John, Annie; Benedict, Sheela European Journal of Pharmacology 2011 10.1016/j.ejphar.2011.06.016
3. Target identification of drug induced mitochondrial toxicity using immunocapture based OXPHOS activity assays. Nadanaciva, Sashi; Bernal, Autumn; Aggeler, Robert; Capaldi, Roderick; Will, Yvonne Toxicology in Vitro 2007 10.1016/j.tiv.2007.01.011
4. Mechanisms of benzarone and benzbromarone-induced hepatic toxicity. Kaufmann, Priska; Török, Michael; Hänni, Anya; Roberts, Paul; Gasser, Rodolfo; Krähenbühl, Stephan Hepatology 2005 10.1002/hep.20634
5. The in vitro and in vivo antitumor effects of clotrimazole on oral squamous cell carcinoma. Wang, Juan; Jia, Lihua; Kuang, Zirong; Wu, Tong; Hong, Yun; Chen, Xiaobing; Leung, W Keung; Xia, Juan; Cheng, Bin Plos One 2014 10.1371/journal.pone.0098885
6. Role of mitochondrial permeability transition in diclofenac-induced hepatocyte injury in rats. Masubuchi, Yasuhiro; Nakayama, Shintaro; Horie, Toshiharu Hepatology 2002 10.1053/jhep.2002.31871
7. Assessment of drug-induced mitochondrial dysfunction via altered cellular respiration and acidification measured in a 96-well platform. Nadanaciva, Sashi; Rana, Payal; Beeson, Gyda C; Chen, Denise; Ferrick, David A; Beeson, Craig C; Will, Yvonne Journal of Bioenergetics and Biomembranes 2012 10.1007/s10863-012-9446-z
8. N-deacetyl ketoconazole-induced hepatotoxicity in a primary culture system of rat hepatocytes. Rodriguez, R J; Acosta, D Toxicology 1997 10.1016/s0300-483x(96)03560-3
9. Inhibitory effects of vitamin K3 on DNA polymerase and angiogenesis Matsubara, International Journal of Molecular Medicine 1905 10.3892/ijmm_00000034
10. Mefloquine selectively increases asynchronous acetylcholine release from motor nerve terminals. McArdle, Joseph J; Sellin, Lawrence C; Coakley, Kathleen M; Potian, Joseph G; Hognason, Kormakur Neuropharmacology 2006 10.1016/j.neuropharm.2005.09.011
11. Generation of free radicals during the reductive metabolism of nilutamide by lung microsomes: possible role in the development of lung lesions in patients treated with this anti-androgen. Berger, V; Berson, A; Wolf, C; Chachaty, C; Fau, D; Fromenty, B; Pessayre, D Biochemical Pharmacology 1992 10.1016/0006-2952(92)90593-8
12. The uncoupling effect of the nonsteroidal anti-inflammatory drug nimesulide in liver mitochondria from adjuvant-induced arthritic rats. Caparroz-Assef, S M; Salgueiro-Pagadigorria, C L; Bersani-Amado, C A; Bracht, A; Kelmer-Bracht, A M; Ishii-Iwamoto, E L Cell Biochemistry and Function 2001 10.1002/cbf.904
13. Nitrofurantoin inhibition of mouse liver mitochondrial respiration involving NAD-linked substrates Lim, Lori O.; Bortell, Rita; Neims, Allen H. Toxicology and Applied Pharmacology 1986 10.1016/0041-008X(86)90254-1
14. Complex I is the major site of mitochondrial superoxide production by paraquat. Cochemé, Helena M; Murphy, Michael P The Journal of Biological Chemistry 2008 10.1074/jbc.M708597200
15. Biguanide-induced mitochondrial dysfunction yields increased lactate production and cytotoxicity of aerobically-poised HepG2 cells and human hepatocytes in vitro. Dykens, James A; Jamieson, Joseph; Marroquin, Lisa; Nadanaciva, Sashi; Billis, Puja A; Will, Yvonne Toxicology and Applied Pharmacology 2008 10.1016/j.taap.2008.08.013
16. Perhexiline. Ashrafian, Houman; Horowitz, John D; Frenneaux, Michael P Cardiovascular drug reviews 1905 10.1111/j.1527-3466.2007.00006.x
17. Metabolic manipulation in ischaemic heart disease, a novel approach to treatment. Lee, Leong; Horowitz, John; Frenneaux, Michael European Heart Journal 2004 10.1016/j.ehj.2004.02.018
18. Comparison of negative inotropic potency, reversibility, and effects on calcium influx of six calcium channel antagonists in cultured myocardial cells. Barry, W H; Horowitz, J D; Smith, T W British Journal of Pharmacology 1985 10.1111/j.1476-5381.1985.tb08830.x
19. Inhibitory effects of some cyclohexylaralkylamines related to perhexiline on sodium influx, binding of [3H]batrachotoxinin A 20-alpha-benzoate and [3H]nitrendipine and on guinea pig left atria contractions. Grima, M; Velly, J; Decker, N; Marciniak, G; Schwartz, J European Journal of Pharmacology 1988 10.1016/0014-2999(88)90776-5
20. Effect of the anti-anginal agent, perhexiline, on neutrophil, valvular and vascular superoxide formation. Kennedy, Jennifer A; Beck-Oldach, Konstanz; McFadden-Lewis, Kate; Murphy, Geraldine A; Wong, Yee W; Zhang, Yi; Horowitz, John D European Journal of Pharmacology 2006 10.1016/j.ejphar.2005.11.058
21. Pioglitazone leads to an inactivation and disassembly of complex I of the mitochondrial respiratory chain. García-Ruiz, Inmaculada; Solís-Muñoz, Pablo; Fernández-Moreira, Daniel; Muñoz-Yagüe, Teresa; Solís-Herruzo, José A BMC Biology 2013 10.1186/1741-7007-11-88
22. Effect of tricyclic drugs on mitochondrial membrane. Eto, K; Fukuda, T; Araki, Y; Inoue, B; Ogata, M Acta medica Okayama 1985 10.18926/AMO/31500
23. Differential effects of typical and atypical neuroleptics on mitochondrial function in vitro. Modica-Napolitano, Josephine S; Lagace, Christopher J; Brennan, William A; Aprille, June R Archives of Pharmacal Research 2003 10.1007/bf02980205
24. 2,4-dinitrophenol (DNP): a weight loss agent with significant acute toxicity and risk of death. Grundlingh, Johann; Dargan, Paul I; El-Zanfaly, Marwa; Wood, David M Journal of Medical Toxicology 2011 10.1007/s13181-011-0162-6
25. Chemosensitizing and cytotoxic effects of 2-deoxy-D-glucose on breast cancer cells. Zhang, Fanjie; Aft, Rebecca L Journal of cancer research and therapeutics 2009 10.4103/0973-1482.55140
26. Mitochondrial electron transport chain complex III is required for antimycin A to inhibit autophagy. Ma, Xiuquan; Jin, Mingzhi; Cai, Yu; Xia, Hongguang; Long, Kai; Liu, Junli; Yu, Qiang; Yuan, Junying Chemistry & Biology 2011 10.1016/j.chembiol.2011.08.009
27. The kinetic mechanism by which CCCP (carbonyl cyanide m-chlorophenylhydrazone) transports protons across membranes. Kasianowicz, J; Benz, R; McLaughlin, S The Journal of Membrane Biology 1905 10.1007/bf01868942
28. Characterization of hepatic mitochondrial injury induced by fatty acid oxidation inhibitors. Vickers, Alison E M Toxicologic Pathology 2009 10.1177/0192623308329285
29. Myxothiazol, a new inhibitor of the cytochrome b-c1 segment of the respiratory chain Thierbach, Georg; Reichenbach, Hans Biochimica et Biophysica Acta (BBA) - Bioenergetics 1981 10.1016/0005-2728(81)90238-3
30. Effect of dopamine, dimethoxyphenylethylamine, papaverine, and related compounds on mitochondrial respiration and complex I activity. Morikawa, N; Nakagawa-Hattori, Y; Mizuno, Y Journal of Neurochemistry 1996 10.1046/j.1471-4159.1996.66031174.x