ID Title Authors Journal Publication Year DOI
269. High-Throughput Small Molecule Screen Identifies Modulators of Mitochondrial Function in Neurons. Varkuti, Boglarka H; Liu, Ze; Kepiro, Miklos; Pacifico, Rodrigo; Gai, Yunchao; Kamenecka, Ted; Davis, Ronald L iScience 1905 10.1016/j.isci.2020.100931
97. New 4-hydroxypyridine and 4-hydroxyquinoline derivatives as inhibitors of NADH-ubiquinone reductase in the respiratory chain. Chung, K H; Cho, K Y; Asami, Y; Takahashi, N; Yoshida, S Zeitschrift fur Naturforschung. C, Journal of Biosciences 1989 10.1515/znc-1989-7-811
146. Inhibition of succinic dehydrogenase and F0F1-ATP synthase by 4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid (DIDS). Bernardes, C F; Meyer-Fernandes, J R; Martins, O B; Vercesi, A E Zeitschrift fur Naturforschung. C, Journal of Biosciences 1997 10.1515/znc-1997-11-1212
111. The 1,2,3-benzothiadiazoles. A new type of compound acting on coupling site I, in rat liver mitochondria. Gil, D L; Ferreira, J; Reynafarje, B Xenobiotica; the Fate of Foreign Compounds in Biological Systems 1980 10.3109/00498258009033725
3. Target identification of drug induced mitochondrial toxicity using immunocapture based OXPHOS activity assays. Nadanaciva, Sashi; Bernal, Autumn; Aggeler, Robert; Capaldi, Roderick; Will, Yvonne Toxicology in Vitro 2007 10.1016/j.tiv.2007.01.011
50. Mitochondrial membrane potential measurement of H9c2 cells grown in high-glucose and galactose-containing media does not provide additional predictivity towards mitochondrial assessment. Rana, Payal; Nadanaciva, Sashi; Will, Yvonne Toxicology in Vitro 2011 10.1016/j.tiv.2010.11.016
35. A combined in vitro approach to improve the prediction of mitochondrial toxicants. Eakins, Julie; Bauch, Caroline; Woodhouse, Heather; Park, Benjamin; Bevan, Samantha; Dilworth, Clive; Walker, Paul Toxicology in Vitro 2016 10.1016/j.tiv.2016.03.016
205. Mitochondrial toxicity of diclofenac and its metabolites via inhibition of oxidative phosphorylation (ATP synthesis) in rat liver mitochondria: Possible role in drug induced liver injury (DILI). Syed, Muzeeb; Skonberg, Christian; Hansen, Steen Honor? Toxicology in Vitro 2016 10.1016/j.tiv.2015.11.020
206. Mitochondrial toxicity of selective COX-2 inhibitors via inhibition of oxidative phosphorylation (ATP synthesis) in rat liver mitochondria. Syed, Muzeeb; Skonberg, Christian; Hansen, Steen Honor? Toxicology in Vitro 2016 10.1016/j.tiv.2015.12.003
58. Involvement of oxidative stress in the hepatotoxicity induced by aromatic antiepileptic drugs. Santos, N A G; Medina, W S G; Martins, N M; Rodrigues, M A Carvalho; Curti, C; Santos, A C Toxicology in Vitro 2008 10.1016/j.tiv.2008.08.004
226. Troglitazone, but not rosiglitazone, damages mitochondrial DNA and induces mitochondrial dysfunction and cell death in human hepatocytes. Rachek, Lyudmila I; Yuzefovych, Larysa V; Ledoux, Susan P; Julie, Neil L; Wilson, Glenn L Toxicology and Applied Pharmacology 2009 10.1016/j.taap.2009.07.021
64. Role of mitochondrial permeability transition in human renal tubular epithelial cell death induced by aristolochic acid. Qi, Xinming; Cai, Yan; Gong, Likun; Liu, Linlin; Chen, Fangping; Xiao, Ying; Wu, Xiongfei; Li, Yan; Xue, Xiang; Ren, Jin Toxicology and Applied Pharmacology 2007 10.1016/j.taap.2007.03.029
40. Toxicity assessments of nonsteroidal anti-inflammatory drugs in isolated mitochondria, rat hepatocytes, and zebrafish show good concordance across chemical classes. Nadanaciva, Sashi; Aleo, Michael D; Strock, Christopher J; Stedman, Donald B; Wang, Huijun; Will, Yvonne Toxicology and Applied Pharmacology 2013 10.1016/j.taap.2013.06.019
86. Comparative developmental toxicity of environmentally relevant oxygenated PAHs. Knecht, Andrea L; Goodale, Britton C; Truong, Lisa; Simonich, Michael T; Swanson, Annika J; Matzke, Melissa M; Anderson, Kim A; Waters, Katrina M; Tanguay, Robert L Toxicology and Applied Pharmacology 2013 10.1016/j.taap.2013.05.006
13. Nitrofurantoin inhibition of mouse liver mitochondrial respiration involving NAD-linked substrates Lim, Lori O.; Bortell, Rita; Neims, Allen H. Toxicology and Applied Pharmacology 1986 10.1016/0041-008X(86)90254-1
91. Quercetin, a natural product supplement, impairs mitochondrial bioenergetics and locomotor behavior in larval zebrafish (Danio rerio). Zhang, Ji-Liang; Laurence Souders, Christopher; Denslow, Nancy D; Martyniuk, Christopher J Toxicology and Applied Pharmacology 2017 10.1016/j.taap.2017.04.024
15. Biguanide-induced mitochondrial dysfunction yields increased lactate production and cytotoxicity of aerobically-poised HepG2 cells and human hepatocytes in vitro. Dykens, James A; Jamieson, Joseph; Marroquin, Lisa; Nadanaciva, Sashi; Billis, Puja A; Will, Yvonne Toxicology and Applied Pharmacology 2008 10.1016/j.taap.2008.08.013
1. Acetaminophen-induced liver injury in rats and mice: comparison of protein adducts, mitochondrial dysfunction, and oxidative stress in the mechanism of toxicity. McGill, Mitchell R; Williams, C David; Xie, Yuchao; Ramachandran, Anup; Jaeschke, Hartmut Toxicology and Applied Pharmacology 2012 10.1016/j.taap.2012.08.015
92. Mitochondrial bioenergetics and locomotor activity are altered in zebrafish (Danio rerio) after exposure to the bipyridylium herbicide diquat. Wang, Xiao H; Souders, Christopher L; Zhao, Yuan H; Martyniuk, Christopher J Toxicology Letters 2018 10.1016/j.toxlet.2017.10.022
60. In vitro inhibition of mitochondrial respiratory rate by antidepressants. Hroudová, Jana; Fišar, Zdeněk Toxicology Letters 2012 10.1016/j.toxlet.2012.07.017
330. Troglitazone induces a rapid drop of mitochondrial membrane potential in liver HepG2 cells. Bova, Michael P; Tam, Danny; McMahon, Gerald; Mattson, Matthew N Toxicology Letters 2005 10.1016/j.toxlet.2004.08.009
66. Effect of ochratoxin A on rat liver mitochondrial respiration and oxidative phosphorylation Wei, Y; Lu, C; Lin, T; Wei, R Toxicology 1985 10.1016/0300-483X(85)90046-0
49. Cytotoxicity of phenothiazine derivatives associated with mitochondrial dysfunction: a structure-activity investigation. de Faria, Priscila A; Bettanin, Fernanda; Cunha, Rodrigo L O R; Paredes-Gamero, Edgar J; Homem-de-Mello, Paula; Nantes, Iseli L; Rodrigues, Tiago Toxicology 2015 10.1016/j.tox.2015.02.004
67. On the effects of paraquat on isolated mitochondria. Evidence that paraquat causes opening of the cyclosporin A-sensitive permeability transition pore synergistically with nitric oxide. Costantini, P; Petronilli, V; Colonna, R; Bernardi, P Toxicology 1995 10.1016/0300-483X(94)02997-9
37. Hepatocellular toxicity of benzbromarone: effects on mitochondrial function and structure. Felser, Andrea; Lindinger, Peter W; Schnell, Dominik; Kratschmar, Denise V; Odermatt, Alex; Mies, Suzette; Jenö, Paul; Krähenbühl, Stephan Toxicology 2014 10.1016/j.tox.2014.08.002
242. Clinical effects of chemical exposures on mitochondrial function. Zolkipli-Cunningham, Zarazuela; Falk, Marni J Toxicology 2017 10.1016/j.tox.2017.07.009
331. Mitochondrial permeability transition as a potential determinant of hepatotoxicity of antidiabetic thiazolidinediones. Masubuchi, Yasuhiro; Kano, Satomi; Horie, Toshiharu Toxicology 2006 10.1016/j.tox.2006.02.017
247. Mitochondrial fusion, fission, and mitochondrial toxicity. Meyer, Joel N; Leuthner, Tess C; Luz, Anthony L Toxicology 1905 10.1016/j.tox.2017.07.019
8. N-deacetyl ketoconazole-induced hepatotoxicity in a primary culture system of rat hepatocytes. Rodriguez, R J; Acosta, D Toxicology 1997 10.1016/s0300-483x(96)03560-3
36. Prediction of liver injury induced by chemicals in human with a multiparametric assay on isolated mouse liver mitochondria. Porceddu, Mathieu; Buron, Nelly; Roussel, Célestin; Labbe, Gilles; Fromenty, Bernard; Borgne-Sanchez, Annie Toxicological Sciences 2012 10.1093/toxsci/kfs197