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"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01525",
"func": "F02110103",
"targ": "T181",
"compound": "D1200: 2-Furancarboxamide, N-[[(4-methoxyphenyl)amino]thioxomethyl]-",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01526",
"func": "F02110103",
"targ": "T181",
"compound": "D1201: 2-Amino-N-quinolin-8-yl-benzenesulfonamide",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01527",
"func": "F02110103",
"targ": "T181",
"compound": "D1202: (5Z)-5-[(4-Fluorophenyl)methylidene]-1-methyl-3-phenyl-1,3-diazinane-2,4,6-trione",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01528",
"func": "F02110103",
"targ": "T181",
"compound": "D1203: 2-[4-(1-Adamantyl)phenoxy]-N,N-diethylethanamine;hydrochloride",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01529",
"func": "F02110103",
"targ": "T181",
"compound": "D1204: (2Z)-2-(Acetylamino)-N-(4-hydroxyphenyl)-3-phenylprop-2-enamide",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01530",
"func": "F02110103",
"targ": "T181",
"compound": "D1205: (5E)-5-[(3-Bromo-4-methoxyphenyl)methylidene]-1-phenyl-2-sulfanylidene-1,3-diazinane-4,6-dione",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01531",
"func": "F02110103",
"targ": "T181",
"compound": "D1206: [(3-{[(4-Bromophenyl)amino]carbonyl}phenyl)thio]acetic acid",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01532",
"func": "F02110103",
"targ": "T181",
"compound": "D1207: 2-[(4-Chlorobenzyl)thio]-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01533",
"func": "F02110103",
"targ": "T181",
"compound": "D1208: 1-(5-Hydroxy-2-methyl-1-phenyl-1H-indol-3-yl)ethanone",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01534",
"func": "F02110103",
"targ": "T181",
"compound": "D1209: 2-[(4-Ethylpiperazin-1-yl)methyl]-4-methoxyphenol",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01535",
"func": "F02110103",
"targ": "T181",
"compound": "D1210: 4-(4-Fluorophenyl)-1,3,5-trimethyl-2,6-diphenylpiperidin-4-ol",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01536",
"func": "F02110103",
"targ": "T181",
"compound": "D1211: N-[(E)-1-[5-(4-Bromophenyl)furan-2-yl]-3-[3-(dimethylamino)propylamino]-3-oxoprop-1-en-2-yl]-4-methylbenzamide",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01537",
"func": "F02110103",
"targ": "T181",
"compound": "D1212: (2Z)-3-{N-[4-(4-Chlorophenyl)phenyl]carbamoyl}prop-2-enoic acid",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01538",
"func": "F02110103",
"targ": "T181",
"compound": "D1213: 4-[(E)-3-(4-Ethylpiperazin-1-yl)prop-1-enyl]-N,N-dimethylaniline",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01539",
"func": "F02110103",
"targ": "T181",
"compound": "D1214: 1,5-Dihydro-4,5-diphenyl-2H-imidazol-2-one",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01540",
"func": "F02110103",
"targ": "T181",
"compound": "D1215: 2-[(E)-2-(4-Chlorophenyl)ethenyl]-1-methyl-1H-benzimidazole",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01541",
"func": "F02110103",
"targ": "T181",
"compound": "D1216: 4-[1-Azabicyclo[2.2.2]octan-3-ylidene-[4-(dimethylamino)phenyl]methyl]-N,N-dimethylaniline;hydrochloride",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01542",
"func": "F02110103",
"targ": "T181",
"compound": "D1217: 4-Oxo-4-((4-(styryl)phenyl)amino)but-2-enoic acid",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01543",
"func": "F02110103",
"targ": "T181",
"compound": "D1218: 2,5-Dianilinoterephthalic acid",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01544",
"func": "F02110103",
"targ": "T181",
"compound": "D1219: 4-Methoxy-N-[4-(thiazol-2-ylsulfinamoyl)-phenyl]-benzamide",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01545",
"func": "F02110103",
"targ": "T181",
"compound": "D1220: 3-[(3,4-Dimethylphenyl)sulfonyl]propanenitrile",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01546",
"func": "F02110103",
"targ": "T181",
"compound": "D1221: 4-[4-(1,3-Benzoxazol-2-yl)anilino]-4-oxobutanoic acid",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01547",
"func": "F02110103",
"targ": "T181",
"compound": "D1222: 1-(3-Chlorophenyl)-2,3,4,5,6,7,8,8a-octahydro-1H-isoquinolin-4a-ol;hydrochloride",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01548",
"func": "F02110103",
"targ": "T181",
"compound": "D1223: 6-Methyl-2-(1,2,2,2-tetrafluoroethyl)-1H-benzimidazole",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01549",
"func": "F02110103",
"targ": "T181",
"compound": "D1224: Ethyl 6-amino-5-cyano-2-methyl-4-(2-nitrophenyl)-4H-pyran-3-carboxylate",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01550",
"func": "F02110103",
"targ": "T181",
"compound": "D1225: N-(2,1,3-Benzoxadiazol-4-yl)-2,2,2-trifluoroacetamide",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01551",
"func": "F02110103",
"targ": "T181",
"compound": "D1226: 4-Tert-butyl-N-(4-methylphenyl)benzamide",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01552",
"func": "F02110103",
"targ": "T181",
"compound": "D1227: 2-Methoxy-4-(morpholin-4-ylmethyl)phenol",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01553",
"func": "F02110103",
"targ": "T181",
"compound": "D1228: Bis((1E)-2-phenylvinyl)phosphinic acid",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01554",
"func": "F02110103",
"targ": "T181",
"compound": "D1229: 1-[2-(Allyloxy)benzyl]-4-benzylpiperidine",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01555",
"func": "F02110103",
"targ": "T181",
"compound": "D1230: 2,5-Diaminoterephthalic acid",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01556",
"func": "F02110103",
"targ": "T181",
"compound": "D1231: N-(1-Adamantylcarbonyl)-N'-(3-cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)thiourea",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01557",
"func": "F02110103",
"targ": "T181",
"compound": "D1232: 2-(Isobutylthio)succinic acid",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01558",
"func": "F02110103",
"targ": "T181",
"compound": "D1233: N-{4-[Acetyl(methyl)amino]phenyl}-4-biphenylcarboxamide",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01559",
"func": "F02110103",
"targ": "T181",
"compound": "D1234: 4-[(E)-3-(2-Ethylpiperidin-1-yl)prop-1-enyl]-N,N-dimethylaniline",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01560",
"func": "F02110103",
"targ": "T181",
"compound": "D1235: 3-(2-Chloro-phenyl)-2-(4-(2-oxo-2H-chromen-3-YL)-thiazol-2-YL)-acrylonitrile",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01561",
"func": "F02110103",
"targ": "T181",
"compound": "D1236: Ethyl (7Z)-2-amino-7-(hydroxyimino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01562",
"func": "F02110103",
"targ": "T181",
"compound": "D1237: 2-Amino-4-(3,4-dichlorophenyl)thiazole",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01563",
"func": "F02110103",
"targ": "T181",
"compound": "D1238: 5-(2-Nitrobenzylidene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01564",
"func": "F02110103",
"targ": "T181",
"compound": "D1239: 3-(4-Bromo-2-thienyl)-2-cyano-2-propenethioamide",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01565",
"func": "F02110103",
"targ": "T181",
"compound": "D1240: Benzyl [(6-amino-3,5-dicyano-4-ethylpyridin-2-yl)sulfanyl]acetate",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01566",
"func": "F02110103",
"targ": "T181",
"compound": "D1241: N-{2-[(1,3-Diphenyl-1H-pyrazol-5-yl)amino]phenyl}benzamide",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01567",
"func": "F02110103",
"targ": "T181",
"compound": "D1242: 2-Butyl-5-methylisophthalic acid",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01568",
"func": "F02110103",
"targ": "T181",
"compound": "D1243: 2-Butylsulfanyl-6-methyl-9H-1,3,4,9-tetraaza-fluorene",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01569",
"func": "F02110103",
"targ": "T181",
"compound": "D1244: 2-Phenyldipyrrolo[1,2-a:2',1'-c]pyrazine",
"paper": "162",
"func_act": "affect",
"targ_act": "inhibitor",
"dose": "∼2.5 µM",
"time": "",
"method": "measurement of superoxide/H2O2 production",
"species": "rat",
"animal_model": "skeletal muscle mitochondria",
"criteria": "",
"result": true
},
{
"rec_id": "RC01570",
"func": "F0108",
"targ": null,
"compound": "D0572: (1,1,3,3-tetramethylbutyl)phenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "2.85±0.86",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01571",
"func": "F0108",
"targ": null,
"compound": "D0573: (1'-ethyl-6,7-dihydro-5h-spiro[furo[2,3-f]indole-3,4'-piperidin]-5-yl)[2'-methyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-yl]methanone hydrochloride",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "6.09±2.54",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01572",
"func": "F0108",
"targ": null,
"compound": "D0574: (2-ethyl-4-{[(4-{[4-(4-methoxyphenyl)piperazin-1-yl]methyl}-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl)methyl]sulfanyl}phenoxy)acetic acid",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "25.29±5.81",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01573",
"func": "F0108",
"targ": null,
"compound": "D0575: (2-nitro-1-propenyl)benzene",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "38.57±15.32",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01574",
"func": "F0108",
"targ": null,
"compound": "D0576: (5-chloro-2-hydroxyphenyl)phenylmethanone",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "29.09±3.36",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01575",
"func": "F0108",
"targ": null,
"compound": "D0577: (5s,8s)-5-(3,4-dichlorophenyl)-8-(methylamino)-5,6,7,8-tetrahydronaphthalene-2-sulfonamide",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "8.31±1.43",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01576",
"func": "F0108",
"targ": null,
"compound": "D0578: (9z)-octadec-9-enamide",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "41.61±7.16",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01577",
"func": "F0108",
"targ": null,
"compound": "D0579: (acryloyloxy)(tributyl)stannane",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "0.19±0.11",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
}
]
}
