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"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01629",
"func": "F0108",
"targ": null,
"compound": "D0628: 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "8.78±1.43",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01630",
"func": "F0108",
"targ": null,
"compound": "D0629: 2,2-bis[(benzoyloxy)methyl]dibenzoate propanediol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "4.32±8.63",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01631",
"func": "F0108",
"targ": null,
"compound": "D0630: 2,2'-dichlorobiphenyl",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "31.09±12.28",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01632",
"func": "F0108",
"targ": null,
"compound": "D0631: 2,2'-dihydroxy-4,4'-dimethoxybenzophenone",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "7.75±1.80",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01633",
"func": "F0108",
"targ": null,
"compound": "D0632: 2,2'-dihydroxy-4-methoxybenzophenone",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "9.89±1.04",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01634",
"func": "F0108",
"targ": null,
"compound": "D0633: 2,2'-methylenebis(4-methyl-6-tert-butylphenol)",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "1.35±0.26",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01635",
"func": "F0108",
"targ": null,
"compound": "D0634: 2,2'-methylenebis(ethyl-6-tert-butylphenol)",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "1.22±0.73",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01636",
"func": "F0108",
"targ": null,
"compound": "D0635: 2,3',4,4'-tetrahydroxybenzophenone",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "7.39±7.14",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01637",
"func": "F0108",
"targ": null,
"compound": "D0636: 2,3,4,5-tetrachlorophenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "4.93±2.04",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01638",
"func": "F0108",
"targ": null,
"compound": "D0637: 2,3,4-trichlorophenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "5.23±1.52",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01639",
"func": "F0108",
"targ": null,
"compound": "D0638: 2,3,5,6-tetrachlorophenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "6.42±2.38",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01640",
"func": "F0108",
"targ": null,
"compound": "D0639: 2,3,5-trichlorophenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "5.80±1.05",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01641",
"func": "F0108",
"targ": null,
"compound": "D0640: 2,4,5-trichlorophenol sodium salt",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "5.05±2.09",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01642",
"func": "F0108",
"targ": null,
"compound": "D0641: 2,4,6-trinitro-1,3-dimethyl-5-tert-butylbenzene",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "20.09±6.09",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01643",
"func": "F0108",
"targ": null,
"compound": "D0642: 2,4-bis(1-methyl-1-phenylethyl)phenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "3.49±1.51",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01644",
"func": "F0108",
"targ": null,
"compound": "D0643: 2,4-diaminoanisole sulfate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "2.51±1.16",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01645",
"func": "F0108",
"targ": null,
"compound": "D0644: 2,4-diaminophenol dihydrochloride",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "3.77±1.06",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01646",
"func": "F0108",
"targ": null,
"compound": "D0645: 2,4-dichloro-3,5-dimethylphenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "5.88±4.85",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01647",
"func": "F0108",
"targ": null,
"compound": "D0646: 2,4-diisopropylphenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "17.23±1.99",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01648",
"func": "F0108",
"targ": null,
"compound": "D0647: 2,4-dinitroanisole",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC01649",
"func": "F0108",
"targ": null,
"compound": "D0648: 2,4-di-tert-butylphenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "3.50±0.73",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01650",
"func": "F0108",
"targ": null,
"compound": "D0649: 2,5-bis(2-methylbutan-2-yl)benzene-1,4-diol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "6.86±3.17",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01651",
"func": "F0108",
"targ": null,
"compound": "D0650: 2,5-dichloroanisole",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC01652",
"func": "F0108",
"targ": null,
"compound": "D0651: 2,5-di-tert-butylbenzene-1,4-diol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "7.41±1.27",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01653",
"func": "F0108",
"targ": null,
"compound": "D0652: 2,6-bis-(1,1-dimethylethyl)-2,5-cyclohexadiene-1,4-dione",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "18.60±12.40",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01654",
"func": "F0108",
"targ": null,
"compound": "D0653: 2,6-di(butan-2-yl)phenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "13.69±3.19",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01655",
"func": "F0108",
"targ": null,
"compound": "D0654: 2,6-diaminopyridine",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "31.28±10.35",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01656",
"func": "F0108",
"targ": null,
"compound": "D0655: 2,6-di-tert-butyl-4-nitrophenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "0.17±0.05",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01657",
"func": "F0108",
"targ": null,
"compound": "D0656: 2,6-toluenediamine",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "15.70±10.03",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01658",
"func": "F0108",
"targ": null,
"compound": "D0657: 24r,25-dihydroxyvitamin d3",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "13.02±2.17",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01659",
"func": "F0108",
"targ": null,
"compound": "D0130: 2-Acetylaminofluorene",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "36.27±10.50",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01660",
"func": "F0108",
"targ": null,
"compound": "D0658: 2-amino-4-(p-nitrophenyl)thiazole",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "3.90±1.78",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01661",
"func": "F0108",
"targ": null,
"compound": "D0659: 2-amino-4,6-dinitrophenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "4.18±2.00",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01662",
"func": "F0108",
"targ": null,
"compound": "D0660: 2-amino-4-chloro-5-nitrophenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "21.51±2.48",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01663",
"func": "F0108",
"targ": null,
"compound": "D0661: 2-amino-4-chlorobenzothiazole",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "29.57±5.09",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01664",
"func": "F0108",
"targ": null,
"compound": "D0662: 2-amino-5-nitrophenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "27.40±14.08",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01665",
"func": "F0108",
"targ": null,
"compound": "D0663: 2-amino-6-nitrobenzothiazole",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "12.69±10.45",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01666",
"func": "F0108",
"targ": null,
"compound": "D0664: 2-aminoanthracene",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "4.71±1.92",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01667",
"func": "F0108",
"targ": null,
"compound": "D0665: 2-aminoanthraquinone",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "0.51±0.29",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01668",
"func": "F0108",
"targ": null,
"compound": "D0666: 2-chloro-4-phenylphenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "15.36±7.86",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01669",
"func": "F0108",
"targ": null,
"compound": "D0667: 2-dodecylisoquinolinium tosylate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "3.53±0.50",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01670",
"func": "F0108",
"targ": null,
"compound": "D0668: 2-ethylphenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC01671",
"func": "F0108",
"targ": null,
"compound": "D0669: 2-hydrazino-4-(4-aminophenyl) thiazole",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "0.06±0.02",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01672",
"func": "F0108",
"targ": null,
"compound": "D0670: 2-hydrazino-4-(4-nitrophenyl)thiazole",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "1.60±0.29",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01673",
"func": "F0108",
"targ": null,
"compound": "D0671: 2-hydrazino-4-phenylthiazole",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "2.32±0.79",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01674",
"func": "F0108",
"targ": null,
"compound": "D0672: 2-hydroxy-4-methoxybenzophenone",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC01675",
"func": "F0108",
"targ": null,
"compound": "D0673: 2-hydroxyanthraquinone",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "3.31±1.38",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01676",
"func": "F0108",
"targ": null,
"compound": "D0674: 2-isopropylphenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC01677",
"func": "F0108",
"targ": null,
"compound": "D0675: 2-isovaleryl-1,3-indanedione",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "5.24±0.90",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01678",
"func": "F0108",
"targ": null,
"compound": "D0676: 2-methyl-1-nitroanthraquinone",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "1.34±0.15",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
}
]
}
