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"compound": "D0728: 4-benzylphenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "15.94±3.38",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01731",
"func": "F0108",
"targ": null,
"compound": "D0729: 4-chloro-1,2-diaminobenzene",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "2.38±1.60",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01732",
"func": "F0108",
"targ": null,
"compound": "D0730: 4-chloro-2-cyclopentylphenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "5.66±1.93",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01733",
"func": "F0108",
"targ": null,
"compound": "D0731: 4-chloro-3,5-dimethylphenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "21.00±0.00",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01734",
"func": "F0108",
"targ": null,
"compound": "D0732: 4-chlorophenyl isocyanate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "0.27±0.11",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01735",
"func": "F0108",
"targ": null,
"compound": "D0733: 4-cumylphenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "3.70±0.82",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01736",
"func": "F0108",
"targ": null,
"compound": "D0734: 4'-demethylepipodophyllotoxin",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "2.66±3.92",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01737",
"func": "F0108",
"targ": null,
"compound": "D0735: 4-dodecylphenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "3.18±0.58",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01738",
"func": "F0108",
"targ": null,
"compound": "D0736: 4-ethylphenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC01739",
"func": "F0108",
"targ": null,
"compound": "D0737: 4-hexyl-4'-cyanobiphenyl",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "42.53±15.42",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01740",
"func": "F0108",
"targ": null,
"compound": "D0738: 4-hydroxybenzophenone",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "41.31±18.12",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01741",
"func": "F0108",
"targ": null,
"compound": "D0739: 4-methyl-2,6-dinitrophenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "26.55±4.57",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01742",
"func": "F0108",
"targ": null,
"compound": "D0740: 4-nitroanthranilic acid",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "38.57±17.22",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01743",
"func": "F0108",
"targ": null,
"compound": "D0741: 4-nitro-n-phenylaniline",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "7.43±6.54",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01744",
"func": "F0108",
"targ": null,
"compound": "D0742: 4-nitrosophenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "4.71±2.31",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01745",
"func": "F0108",
"targ": null,
"compound": "D0743: 4-octyloxybenzoic acid",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "39.63±31.34",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01746",
"func": "F0108",
"targ": null,
"compound": "D0744: 4-octylphenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "8.77±2.96",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01747",
"func": "F0108",
"targ": null,
"compound": "D0745: 4-phenoxyphenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "27.97±10.62",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01748",
"func": "F0108",
"targ": null,
"compound": "D0746: 4-styrylpyridine",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "11.22±5.54",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01749",
"func": "F0108",
"targ": null,
"compound": "D0747: 4-tert-butylcatechol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "34.27±14.96",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01750",
"func": "F0108",
"targ": null,
"compound": "D0748: 4-tert-butylphenyl salicylate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "28.37±3.64",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01751",
"func": "F0108",
"targ": null,
"compound": "D0749: 5,7-dichloro-8-hydroxy-2-methylquinoline",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "11.01±2.00",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01752",
"func": "F0108",
"targ": null,
"compound": "D0750: 5alpha-dihydrotestosterone",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "13.30±6.16",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01753",
"func": "F0108",
"targ": null,
"compound": "D0751: 5hpp-33",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "2.09±0.87",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01754",
"func": "F0108",
"targ": null,
"compound": "D0752: Busulfan",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "14.43±5.99",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01755",
"func": "F0108",
"targ": null,
"compound": "D0753: 5-nitroacenaphthene",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "34.38±20.44",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01756",
"func": "F0108",
"targ": null,
"compound": "D0754: 6-hydroxy-2-naphthyl disulfide",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "33.74±3.64",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01757",
"func": "F0108",
"targ": null,
"compound": "D0755: 6-nitrobenzimidazole",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "36.41±10.82",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01758",
"func": "F0108",
"targ": null,
"compound": "D0756: 6-nitroquinoline",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "30.73±11.46",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01759",
"func": "F0108",
"targ": null,
"compound": "D0757: 9,10-dihydrobenzo[a]pyren-7(8h)-one",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "9.81±2.08",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01760",
"func": "F0108",
"targ": null,
"compound": "D0758: 9-aminoacridine, monohydrochloride, monohydrate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "13.80±1.75",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01761",
"func": "F0108",
"targ": null,
"compound": "D0759: 9-anthracenemethanol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "34.48±11.46",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01762",
"func": "F0108",
"targ": null,
"compound": "D0760: 9-cyanoanthracene",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "6.85±18.05",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01763",
"func": "F0108",
"targ": null,
"compound": "D0761: 9-nitroanthracene",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "21.44±12.82",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01764",
"func": "F0108",
"targ": null,
"compound": "D0762: 9-phenanthrol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "1.22±0.56",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01765",
"func": "F0108",
"targ": null,
"compound": "D0763: acenocoumarol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "8.36±1.07",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01766",
"func": "F0108",
"targ": null,
"compound": "D0764: acetaldehyde",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "18.02±6.38",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01767",
"func": "F0108",
"targ": null,
"compound": "D0765: aclarubicin hydrochloride",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "3.15±2.82",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01768",
"func": "F0108",
"targ": null,
"compound": "D0766: acriflavine hydrochloride",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "0.94±0.44",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01769",
"func": "F0108",
"targ": null,
"compound": "D0309: Albendazole",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "9.35±1.83",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01770",
"func": "F0108",
"targ": null,
"compound": "D0767: aldrin",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "31.20±7.21",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01771",
"func": "F0108",
"targ": null,
"compound": "D0768: alizarin",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "11.01±1.41",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01772",
"func": "F0108",
"targ": null,
"compound": "D0769: allylestrenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "12.83±3.68",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01773",
"func": "F0108",
"targ": null,
"compound": "D0770: aloe-emodin",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "1.79±1.54",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01774",
"func": "F0108",
"targ": null,
"compound": "D0771: alpha-1,2,3,4,5,6-hexachlorocyclohexane",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "49.00±6.35",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01775",
"func": "F0108",
"targ": null,
"compound": "D0772: alpha-amylcinnamyl alcohol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "38.11±17.40",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01776",
"func": "F0108",
"targ": null,
"compound": "D0773: ambazone",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "5.60±3.23",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01777",
"func": "F0108",
"targ": null,
"compound": "D0774: ami-193",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "5.82±3.05",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC01778",
"func": "F0108",
"targ": null,
"compound": "D0775: aminoquinuride dihydrochloride",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "25.01±4.09",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
}
]
}
