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"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02030",
"func": "F0108",
"targ": null,
"compound": "D1012: n-cyclohexyl-4-methyl benzenesulfonamide",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "36.15±20.97",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02031",
"func": "F0108",
"targ": null,
"compound": "D1013: nelfinavir mesylate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "11.88±6.92",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02032",
"func": "F0108",
"targ": null,
"compound": "D0374: Niclosamide",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "0.03±0.01",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02033",
"func": "F0108",
"targ": null,
"compound": "D1014: niflumic acid",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "13.02±2.17",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02034",
"func": "F0108",
"targ": null,
"compound": "D1015: nifuroxazide",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "1.57±0.30",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02035",
"func": "F0108",
"targ": null,
"compound": "D0092: Nimesulide",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "3.87±0.23",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02036",
"func": "F0108",
"targ": null,
"compound": "D1016: ninhydrin",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "32.00±9.69",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02037",
"func": "F0108",
"targ": null,
"compound": "D0376: Nitazoxanide",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "1.04±0.96",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02038",
"func": "F0108",
"targ": null,
"compound": "D0377: Nitrofurantoin",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "26.31±6.35",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02039",
"func": "F0108",
"targ": null,
"compound": "D1017: nitromide",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC02040",
"func": "F0108",
"targ": null,
"compound": "D1018: nitrovin",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "3.27±0.57",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02041",
"func": "F0108",
"targ": null,
"compound": "D1019: nitroxoline",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "9.22±2.41",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02042",
"func": "F0108",
"targ": null,
"compound": "D1020: n-methyl-n,n-dioctyloctan-1-aminium chloride",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "2.73±0.32",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02043",
"func": "F0108",
"targ": null,
"compound": "D1021: n-nitroso-n-methyl-4-nitroaniline",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC02044",
"func": "F0108",
"targ": null,
"compound": "D1022: nocodazole",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "3.53±1.63",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02045",
"func": "F0108",
"targ": null,
"compound": "D1023: nonylparaben",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "4.43±0.30",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02046",
"func": "F0108",
"targ": null,
"compound": "D1024: norelgestromin",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "13.53±6.64",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02047",
"func": "F0108",
"targ": null,
"compound": "D1025: noristerat",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "9.81±1.78",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02048",
"func": "F0108",
"targ": null,
"compound": "D1026: novaluron",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC02049",
"func": "F0108",
"targ": null,
"compound": "D1027: n-phenyl-1,4-benzenediamine hydrochloride",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "5.82±6.96",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02050",
"func": "F0108",
"targ": null,
"compound": "D1028: o,p'-ddd",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "19.83±0.94",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02051",
"func": "F0108",
"targ": null,
"compound": "D1029: o,p'-ddt",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "23.98±12.11",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02052",
"func": "F0108",
"targ": null,
"compound": "D1030: olvanil",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "13.53±1.90",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02053",
"func": "F0108",
"targ": null,
"compound": "D1031: osalmid",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "6.68±0.77",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02054",
"func": "F0108",
"targ": null,
"compound": "D1032: ouabain",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "0.18±0.00",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02055",
"func": "F0108",
"targ": null,
"compound": "D1033: oxyphenisatin acetate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "5.49±4.60",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02056",
"func": "F0108",
"targ": null,
"compound": "D1034: p,p'-ddd",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "15.19±8.82",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02057",
"func": "F0108",
"targ": null,
"compound": "D1035: p,p'-dde",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "25.60±1.71",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02058",
"func": "F0108",
"targ": null,
"compound": "D1036: p,p'-ddt",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "24.26±2.74",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02059",
"func": "F0108",
"targ": null,
"compound": "D1037: palmatine chloride hydrate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "22.74±5.23",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02060",
"func": "F0108",
"targ": null,
"compound": "D1038: paricalcitol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "8.91±1.56",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02061",
"func": "F0108",
"targ": null,
"compound": "D1039: p-benzoquinone dioxime",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "43.30±14.86",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02062",
"func": "F0108",
"targ": null,
"compound": "D1040: penfluridol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "33.49±0.00",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02063",
"func": "F0108",
"targ": null,
"compound": "D0625: 2,2',4,4',5-pentabromodiphenyl ether",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "15.46±7.01",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02064",
"func": "F0108",
"targ": null,
"compound": "D1042: pentabromophenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "3.46±0.99",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02065",
"func": "F0108",
"targ": null,
"compound": "D0223: Pentachlorophenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "3.09±0.60",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02066",
"func": "F0108",
"targ": null,
"compound": "D1043: pentylparaben",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "8.74±1.65",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02067",
"func": "F0108",
"targ": null,
"compound": "D1044: perfluorooctanesulfonamide",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "2.43±0.81",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02068",
"func": "F0108",
"targ": null,
"compound": "D1045: phenazopyridine hydrochloride",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "15.72±3.45",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02069",
"func": "F0108",
"targ": null,
"compound": "D1046: phenindione",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC02070",
"func": "F0108",
"targ": null,
"compound": "D1047: phenmedipham",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "4.41±2.02",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02071",
"func": "F0108",
"targ": null,
"compound": "D1048: phenol, 2-(1,1-dimethylethyl)-6-methyl-",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC02072",
"func": "F0108",
"targ": null,
"compound": "D1049: phenol, 4,4'-butylidenebis[2-(1,1-dimethylethyl)-5-methyl-",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "5.51±1.58",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02073",
"func": "F0108",
"targ": null,
"compound": "D1050: phenol, 4-methyl-, reaction products with dicyclopentadiene and isobutylene",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "15.55±8.56",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02074",
"func": "F0108",
"targ": null,
"compound": "D1051: phenolphthalein",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "42.78±2.74",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02075",
"func": "F0108",
"targ": null,
"compound": "D1052: phenoxybenzamine hydrochloride",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "48.80±9.17",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
}
]
}
