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"compound": "D1102: su-5416",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "12.53±1.78",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02130",
"func": "F0108",
"targ": null,
"compound": "D1103: sulfanitran",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "26.60±8.77",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02131",
"func": "F0108",
"targ": null,
"compound": "D1104: surinabant",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "33.08±16.61",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02132",
"func": "F0108",
"targ": null,
"compound": "D1105: talniflumate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "27.00±2.56",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02133",
"func": "F0108",
"targ": null,
"compound": "D1106: tamibarotene",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "25.68±1.05",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02134",
"func": "F0108",
"targ": null,
"compound": "D1107: tamsulosin hydrochloride",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "27.20±2.92",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02135",
"func": "F0108",
"targ": null,
"compound": "D1108: tau-fluvalinate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "37.16±15.12",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02136",
"func": "F0108",
"targ": null,
"compound": "D0489: tenidap",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "12.53±1.19",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02137",
"func": "F0108",
"targ": null,
"compound": "D1109: tenonitrozole",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "0.73±0.12",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02138",
"func": "F0108",
"targ": null,
"compound": "D1110: tenovin-1",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "3.27±2.74",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02139",
"func": "F0108",
"targ": null,
"compound": "D1111: tenoxicam",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "8.36±1.07",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02140",
"func": "F0108",
"targ": null,
"compound": "D1112: tert-butyl 4-hydroxybenzoate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "25.29±7.32",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02141",
"func": "F0108",
"targ": null,
"compound": "D1113: tetra-aminopyrimidine sulfate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "18.70±11.39",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02142",
"func": "F0108",
"targ": null,
"compound": "D1114: tetrabromophenolphthalein ethyl ester",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "23.80±6.89",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02143",
"func": "F0108",
"targ": null,
"compound": "D1115: tetrabutylphosphonium chloride",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC02144",
"func": "F0108",
"targ": null,
"compound": "D1116: tetrabutyltin",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "5.66±1.03",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02145",
"func": "F0108",
"targ": null,
"compound": "D1117: tetradecylpyridinium bromide",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "22.54±4.10",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02146",
"func": "F0108",
"targ": null,
"compound": "D1118: tetradifon",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "15.34±7.43",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02147",
"func": "F0108",
"targ": null,
"compound": "D1119: tetraiodoethene",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "5.45±1.27",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02148",
"func": "F0108",
"targ": null,
"compound": "D1120: tetra-n-octylammonium bromide",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "0.13±0.09",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02149",
"func": "F0108",
"targ": null,
"compound": "D1121: tetraoctylphosphonium bromide",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "0.18±0.12",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02150",
"func": "F0108",
"targ": null,
"compound": "D1122: tetrasul",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "1.77±0.25",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02151",
"func": "F0108",
"targ": null,
"compound": "D1123: thidiazuron",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "3.43±0.73",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02152",
"func": "F0108",
"targ": null,
"compound": "D1124: thiram",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "1.94±25.92",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02153",
"func": "F0108",
"targ": null,
"compound": "D1125: tibrofan",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "0.79±0.11",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02154",
"func": "F0108",
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"compound": "D1126: tioxidazole",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "7.50±1.75",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02155",
"func": "F0108",
"targ": null,
"compound": "D0120: Tipranavir",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "26.60±4.94",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02156",
"func": "F0108",
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"compound": "D1127: tolclofos-methyl",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "30.64±5.80",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02157",
"func": "F0108",
"targ": null,
"compound": "D0122: Tolfenamic Acid",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "11.88±0.00",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02158",
"func": "F0108",
"targ": null,
"compound": "D1128: toluidine blue",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "3.48±1.60",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02159",
"func": "F0108",
"targ": null,
"compound": "D1129: tolvaptan",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "17.44±8.01",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02160",
"func": "F0108",
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"compound": "D1130: transfluthrin",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "25.01±4.09",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02161",
"func": "F0108",
"targ": null,
"compound": "D1131: tribenoside",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "11.80±0.80",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02162",
"func": "F0108",
"targ": null,
"compound": "D1132: tribromosalan",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "1.12±0.00",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02163",
"func": "F0108",
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"compound": "D1133: tributyltetradecylphosphonium chloride",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "0.71±0.15",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02164",
"func": "F0108",
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"compound": "D1134: tributyltin benzoate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "0.15±0.23",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02165",
"func": "F0108",
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"compound": "D1135: tributyltin chloride",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "0.11±0.02",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02166",
"func": "F0108",
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"compound": "D1136: tributyltin methacrylate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "0.07±0.01",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02167",
"func": "F0108",
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"compound": "D1137: tricirbine",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "1.21±1.51",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02168",
"func": "F0108",
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"compound": "D1138: triclabendazole",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "1.84±0.15",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02169",
"func": "F0108",
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"compound": "D1139: triclocarban",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "0.14±0.05",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02170",
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"compound": "D1140: triclosan",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "1.50±0.88",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02171",
"func": "F0108",
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"compound": "D1141: triethoxy(2-methylpropyl)silane",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "28.92±6.98",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02172",
"func": "F0108",
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"compound": "D1142: triethyltin bromide",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "0.02±0.02",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03611",
"func": "F0105",
"targ": null,
"compound": "D0069: Indomethacin",
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"func_act": "",
"targ_act": "",
"dose": "",
"time": "",
"method": "",
"species": "",
"animal_model": "",
"criteria": "",
"result": true
},
{
"rec_id": "RC02173",
"func": "F0108",
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"compound": "D1143: trifluralin",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "46.68±9.14",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02174",
"func": "F0108",
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"compound": "D1144: trihexyltetradecylphosphonium bromide",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "0.84±0.24",
"time": "",
"method": "MMP assay",
"species": "human",
"animal_model": "qHTS-HepG2",
"criteria": "IC50",
"result": true
}
]
}
