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{
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"func": "F0108",
"targ": null,
"compound": "D0685: 2-propenal,3,3-diphenyl-",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "17.12±23.88",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02930",
"func": "F0108",
"targ": null,
"compound": "D0686: 2-tert-butyl-4-ethylphenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC02931",
"func": "F0108",
"targ": null,
"compound": "D0687: 2-tert-butyl-4-methoxyphenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "36.50±19.25",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02932",
"func": "F0108",
"targ": null,
"compound": "D0688: 2-tert-butyl-5-methylphenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "40.07±6.50",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02933",
"func": "F0108",
"targ": null,
"compound": "D0689: 3-(5,5,6-trimethylbicyclo[2.2.1]hept-2-yl)cyclohexanol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC02934",
"func": "F0108",
"targ": null,
"compound": "D0690: 3,3',4,4'-tetraaminobiphenyl tetrahydrochloride",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "9.46±4.43",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02935",
"func": "F0108",
"targ": null,
"compound": "D0691: 3,3',5,5'-tetraiodothyroacetic acid",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "26.13±2.13",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02936",
"func": "F0108",
"targ": null,
"compound": "D0692: 3,3'-diaminobenzidine",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "30.66±28.30",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02937",
"func": "F0108",
"targ": null,
"compound": "D0693: 3,3'-dimethylbisphenol a",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "34.35±4.73",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02938",
"func": "F0108",
"targ": null,
"compound": "D0694: 3,3φ,5,5φ-tetrabromobisphenol a",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "36.91±12.56",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02939",
"func": "F0108",
"targ": null,
"compound": "D0695: 3,4,5-trichlorophenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "33.82±17.20",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02940",
"func": "F0108",
"targ": null,
"compound": "D0696: 3,4-dichlorophenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "53.88±13.03",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02941",
"func": "F0108",
"targ": null,
"compound": "D0697: 3,5-dichlorophenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "46.90±8.44",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02942",
"func": "F0108",
"targ": null,
"compound": "D0698: 3,5-dichlorosalicyl-3,4-dichloroanilide",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "0.38±0.03",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02943",
"func": "F0108",
"targ": null,
"compound": "D0699: 3-acetylphenanthrene",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "42.21±19.83",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02944",
"func": "F0108",
"targ": null,
"compound": "D0700: 3-amino-9-ethylcarbazole hydrochloride",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "56.23±0.00",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02945",
"func": "F0108",
"targ": null,
"compound": "D0701: 3-aminophenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC02946",
"func": "F0108",
"targ": null,
"compound": "D0702: 3-hydroxybenzophenone",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC02947",
"func": "F0108",
"targ": null,
"compound": "D0703: 3-hydroxy-n-(3-nitrophenyl)naphthalene-2-carboxamide",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "1.60±0.26",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02948",
"func": "F0108",
"targ": null,
"compound": "D0704: 3-hydroxy-n-phenylaniline",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC02949",
"func": "F0108",
"targ": null,
"compound": "D0705: 3-methylbenzene-1,2-diamine",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "36.64±11.80",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02950",
"func": "F0108",
"targ": null,
"compound": "D0706: 3-methylcholanthrene",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC02951",
"func": "F0108",
"targ": null,
"compound": "D0707: 3-methyl-n-phenylaniline",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "35.48±0.00",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02952",
"func": "F0108",
"targ": null,
"compound": "D0708: 4-(1,1,3,3-tetramethylbutyl)phenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC02953",
"func": "F0108",
"targ": null,
"compound": "D0709: 4-(2-methylbutan-2-yl)phenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC02954",
"func": "F0108",
"targ": null,
"compound": "D0710: 4-(3-phenylpropyl)pyridine",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "12.95±6.83",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02955",
"func": "F0108",
"targ": null,
"compound": "D0711: 4-(benzyloxyl)phenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "9.04±8.10",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02956",
"func": "F0108",
"targ": null,
"compound": "D0712: 4-(butan-2-yl)phenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC02957",
"func": "F0108",
"targ": null,
"compound": "D0713: 4,4,4-trifluoro-1-phenyl-1,3-butanedione",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC02958",
"func": "F0108",
"targ": null,
"compound": "D0714: 4,4'-diaminoazobenzene",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "26.63±12.51",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02959",
"func": "F0108",
"targ": null,
"compound": "D0715: 4,4'-diaminobenzanilide",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "33.55±2.73",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02960",
"func": "F0108",
"targ": null,
"compound": "D0716: 4,4'-dichlorodiphenyl sulfone",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "29.90±2.43",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02961",
"func": "F0108",
"targ": null,
"compound": "D0717: 4,4'-dinitrodiphenylurea",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "0.70±0.46",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02962",
"func": "F0108",
"targ": null,
"compound": "D0718: 4,4'-methylenebis(2,6-di-t-butylphenol)",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC02963",
"func": "F0108",
"targ": null,
"compound": "D0719: 4,4'-methylenebis(2-chloroaniline)",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "56.23±0.00",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02964",
"func": "F0108",
"targ": null,
"compound": "D0720: 4,4'-sulfonylbis[2-(prop-2-en-1-yl)phenol]",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "24.48±19.89",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02965",
"func": "F0108",
"targ": null,
"compound": "D0721: 4,4'-thiobis(6-tert-butyl-m-cresol)",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "24.82±11.78",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02966",
"func": "F0108",
"targ": null,
"compound": "D0722: 4,4'-thiodiphenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "24.70±9.79",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02967",
"func": "F0108",
"targ": null,
"compound": "D0723: 4,6-dichloro-1,3-benzenediol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "35.72±5.79",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02968",
"func": "F0108",
"targ": null,
"compound": "D0724: 4,6-di-tert-butyl-m-cresol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "45.86±14.67",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02969",
"func": "F0108",
"targ": null,
"compound": "D0725: 4-amino-2,6-dichlorophenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "29.55±27.78",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02970",
"func": "F0108",
"targ": null,
"compound": "D0726: 4-amino-2-nitrophenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "33.55±2.73",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02971",
"func": "F0108",
"targ": null,
"compound": "D0727: 4-amino-4φ-hydroxy-3-methyldiphenylamine",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC02972",
"func": "F0108",
"targ": null,
"compound": "D0728: 4-benzylphenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC02973",
"func": "F0108",
"targ": null,
"compound": "D0729: 4-chloro-1,2-diaminobenzene",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "11.03±4.37",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02974",
"func": "F0108",
"targ": null,
"compound": "D0730: 4-chloro-2-cyclopentylphenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "33.65±29.67",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC02975",
"func": "F0108",
"targ": null,
"compound": "D0731: 4-chloro-3,5-dimethylphenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
}
]
}
