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"func_act": "decrease",
"targ_act": "",
"dose": "35.97±7.53",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03032",
"func": "F0108",
"targ": null,
"compound": "D0787: bardoxolone methyl",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "17.41±2.00",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03033",
"func": "F0108",
"targ": null,
"compound": "D0788: barium bis(2-ethylhexanoate)",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03034",
"func": "F0108",
"targ": null,
"compound": "D0789: barium chloride",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03035",
"func": "F0108",
"targ": null,
"compound": "D0790: basic blue 7",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "1.53±1.42",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03036",
"func": "F0108",
"targ": null,
"compound": "D0791: bazedoxifene",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03037",
"func": "F0108",
"targ": null,
"compound": "D0792: beclazone",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "16.28±20.57",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03038",
"func": "F0108",
"targ": null,
"compound": "D0419: benzbromarone",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "4.91±1.79",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03039",
"func": "F0108",
"targ": null,
"compound": "D0793: benzidine",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "2.51±3.54",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03040",
"func": "F0108",
"targ": null,
"compound": "D0794: benzidine dihydrochloride",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03041",
"func": "F0108",
"targ": null,
"compound": "D0795: benziodarone",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "1.76±0.68",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03042",
"func": "F0108",
"targ": null,
"compound": "D0796: benzobarbital",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03043",
"func": "F0108",
"targ": null,
"compound": "D0797: benzoic acid, 2-[(4-chloro-3-methylphenyl)amino]-",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "22.71±16.22",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03044",
"func": "F0108",
"targ": null,
"compound": "D0798: benzyldimethyltetradecylammonium chloride dihydrate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03045",
"func": "F0108",
"targ": null,
"compound": "D0799: benzyldodecyldimethylammonium bromide",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "18.39±1.50",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03046",
"func": "F0108",
"targ": null,
"compound": "D0800: benzylhydrazine dihydrochloride",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03047",
"func": "F0108",
"targ": null,
"compound": "D0801: berberine chloride",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "6.03±3.78",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03048",
"func": "F0108",
"targ": null,
"compound": "D0802: betamethasone dipropionate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03049",
"func": "F0108",
"targ": null,
"compound": "D0803: bexarotene",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "9.08±1.16",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03050",
"func": "F0108",
"targ": null,
"compound": "D0804: bis(tributyltin)oxide",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03051",
"func": "F0108",
"targ": null,
"compound": "D0805: bisacodyl",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "18.39±13.00",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03052",
"func": "F0108",
"targ": null,
"compound": "D0149: Bisphenol A",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "37.65±3.06",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03053",
"func": "F0108",
"targ": null,
"compound": "D0806: bisphenol a glycidyl methacrylate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "38.15±9.22",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03054",
"func": "F0108",
"targ": null,
"compound": "D0807: bisphenol af",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "37.26±6.70",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03055",
"func": "F0108",
"targ": null,
"compound": "D0808: bisphenol b",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "21.75±8.60",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03056",
"func": "F0108",
"targ": null,
"compound": "D0809: bisphenol e",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "36.50±19.25",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03057",
"func": "F0108",
"targ": null,
"compound": "D0810: bisphenol z",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "14.71±15.12",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03058",
"func": "F0108",
"targ": null,
"compound": "D0811: bithionol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "2.47±1.39",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03059",
"func": "F0108",
"targ": null,
"compound": "D0812: bosutinib",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "16.59±11.17",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03060",
"func": "F0108",
"targ": null,
"compound": "D0813: bromadiolone",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "3.40±0.83",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03061",
"func": "F0108",
"targ": null,
"compound": "D0814: bromociclen",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03062",
"func": "F0108",
"targ": null,
"compound": "D0815: bromocriptine",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "13.20±10.83",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03063",
"func": "F0108",
"targ": null,
"compound": "D0816: bromocriptine mesylate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "12.57±1.60",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03064",
"func": "F0108",
"targ": null,
"compound": "D0817: bromofenoxim",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "2.18±0.86",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03065",
"func": "F0108",
"targ": null,
"compound": "D0818: bromofos",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "22.65±10.42",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03066",
"func": "F0108",
"targ": null,
"compound": "D0819: bromoxynil octanoate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "28.63±22.68",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03067",
"func": "F0108",
"targ": null,
"compound": "D0820: broquinaldol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "38.61±34.63",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03068",
"func": "F0108",
"targ": null,
"compound": "D0821: bryostatin 1",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "0.79±1.07",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03069",
"func": "F0108",
"targ": null,
"compound": "D0822: buclizine dihydrochloride",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03070",
"func": "F0108",
"targ": null,
"compound": "D0823: butylparaben",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03071",
"func": "F0108",
"targ": null,
"compound": "D0824: c.i. 1040",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "19.72±4.13",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03072",
"func": "F0108",
"targ": null,
"compound": "D0825: c.i. basic orange 2",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "24.91±21.08",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03073",
"func": "F0108",
"targ": null,
"compound": "D0826: c.i. basic red 9 monohydrochloride",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "4.11±4.24",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03074",
"func": "F0108",
"targ": null,
"compound": "D0827: c.i. basic violet 14",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "6.84±4.71",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03075",
"func": "F0108",
"targ": null,
"compound": "D0828: c.i. disperse blue 27",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "32.46±10.39",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
}
]
}
