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"func": "F0108",
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"paper": "163",
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"targ_act": "",
"dose": "49.29±19.53",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03133",
"func": "F0108",
"targ": null,
"compound": "D0882: diflorasone diacetate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
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"func": "F0108",
"targ": null,
"compound": "D0883: digitoxin",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03135",
"func": "F0108",
"targ": null,
"compound": "D0884: digoxin",
"paper": "163",
"func_act": "decrease",
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"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03136",
"func": "F0108",
"targ": null,
"compound": "D0885: dihydrotachysterol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03137",
"func": "F0108",
"targ": null,
"compound": "D0886: dimefline hydrochloride",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03138",
"func": "F0108",
"targ": null,
"compound": "D0887: dinex",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "1.40±0.60",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03139",
"func": "F0108",
"targ": null,
"compound": "D0888: diniconazole",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "36.04±28.56",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03140",
"func": "F0108",
"targ": null,
"compound": "D0889: dinobuton",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "5.74±4.21",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03141",
"func": "F0108",
"targ": null,
"compound": "D0890: dinocap",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "4.10±2.16",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03142",
"func": "F0108",
"targ": null,
"compound": "D0891: dinoterb",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "0.76±0.45",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03143",
"func": "F0108",
"targ": null,
"compound": "D0892: diphenan",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "84.22±39.58",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03144",
"func": "F0108",
"targ": null,
"compound": "D0893: diphenoxylate hydrochloride",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "19.45±0.00",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03145",
"func": "F0108",
"targ": null,
"compound": "D0894: diphenylcyclopropenone",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03146",
"func": "F0108",
"targ": null,
"compound": "D0895: diphenylurea",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "8.46±2.39",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03147",
"func": "F0108",
"targ": null,
"compound": "D0896: disperse red 82",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "11.68±8.76",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03148",
"func": "F0108",
"targ": null,
"compound": "D0897: dithiazanine chloride",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "2.45±0.00",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03149",
"func": "F0108",
"targ": null,
"compound": "D0898: dithiazanine iodide",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "0.98±0.16",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03150",
"func": "F0108",
"targ": null,
"compound": "D0899: docetaxel",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "12.07±4.78",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03151",
"func": "F0108",
"targ": null,
"compound": "D0900: dodecyl gallate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "48.72±8.30",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03152",
"func": "F0108",
"targ": null,
"compound": "D0901: dodecylparaben",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03153",
"func": "F0108",
"targ": null,
"compound": "D0902: dodecylphenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "41.11±13.24",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03154",
"func": "F0108",
"targ": null,
"compound": "D0903: doramapimod;bibr-796?",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "24.08±9.54",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03155",
"func": "F0108",
"targ": null,
"compound": "D0904: doramectin",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03156",
"func": "F0108",
"targ": null,
"compound": "D0905: ebselen",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "21.42±5.35",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03157",
"func": "F0108",
"targ": null,
"compound": "D0906: emodin",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "6.28±4.57",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03158",
"func": "F0108",
"targ": null,
"compound": "D0907: endosulfan sulfate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "25.80±10.10",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03159",
"func": "F0108",
"targ": null,
"compound": "D0908: endrin",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03160",
"func": "F0108",
"targ": null,
"compound": "D0909: enterolactone",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03161",
"func": "F0108",
"targ": null,
"compound": "D0910: eprinomectin (b1a, b1b mixture)",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "8.28±2.44",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03162",
"func": "F0108",
"targ": null,
"compound": "D0911: equilin",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "39.15±15.51",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03163",
"func": "F0108",
"targ": null,
"compound": "D0912: ergotamine d-tartrate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03164",
"func": "F0108",
"targ": null,
"compound": "D0913: estradiol acetate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03165",
"func": "F0108",
"targ": null,
"compound": "D0914: estradiol phosphate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03166",
"func": "F0108",
"targ": null,
"compound": "D0915: ethacridine lactate hydrate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "10.25±5.58",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03167",
"func": "F0108",
"targ": null,
"compound": "D0916: ethalfluralin",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03168",
"func": "F0108",
"targ": null,
"compound": "D0917: ethanol, 2,2'-((1-methylethylidene)bis((2,6-dibromo-4,1-phenylene)oxy))bis-",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "32.82±2.67",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03169",
"func": "F0108",
"targ": null,
"compound": "D0918: ethoxazene",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "4.96±3.42",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03170",
"func": "F0108",
"targ": null,
"compound": "D0919: ethyl linolenate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03171",
"func": "F0108",
"targ": null,
"compound": "D0479: ethynodiol diacetate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03172",
"func": "F0108",
"targ": null,
"compound": "D0920: etocarlide",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "27.65±10.40",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03173",
"func": "F0108",
"targ": null,
"compound": "D0921: everolimus",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "13.01±7.49",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03174",
"func": "F0108",
"targ": null,
"compound": "D0922: exalamide",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "29.15±2.37",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03175",
"func": "F0108",
"targ": null,
"compound": "D0923: ezetimibe",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "16.64±20.07",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
}
]
}
