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"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "1.30±0.29",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03233",
"func": "F0108",
"targ": null,
"compound": "D0977: lercanidipine hydrochloride",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "27.48±0.00",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03234",
"func": "F0108",
"targ": null,
"compound": "D0978: lestaurtinib",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "12.76±2.67",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03235",
"func": "F0108",
"targ": null,
"compound": "D0979: lopinavir",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "15.42±21.79",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03236",
"func": "F0108",
"targ": null,
"compound": "D0980: lornoxicam",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "3.30±2.52",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03237",
"func": "F0108",
"targ": null,
"compound": "D0981: lufenuron",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "44.96±7.29",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03238",
"func": "F0108",
"targ": null,
"compound": "D0982: lynestrenol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03239",
"func": "F0108",
"targ": null,
"compound": "D0983: lysergide",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03240",
"func": "F0108",
"targ": null,
"compound": "D0984: malachite green oxalate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "8.67±12.26",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03241",
"func": "F0108",
"targ": null,
"compound": "D0985: malotilate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "23.92±29.35",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03242",
"func": "F0108",
"targ": null,
"compound": "D0986: manidipine",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "20.91±5.06",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03243",
"func": "F0108",
"targ": null,
"compound": "D0366: Mebendazole",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03244",
"func": "F0108",
"targ": null,
"compound": "D0079: Meloxicam",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03245",
"func": "F0108",
"targ": null,
"compound": "D0987: mepartricin",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "27.66±4.48",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03246",
"func": "F0108",
"targ": null,
"compound": "D0988: mepronil",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "56.23±0.00",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03247",
"func": "F0108",
"targ": null,
"compound": "D0989: mesotrione",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03248",
"func": "F0108",
"targ": null,
"compound": "D0990: metanixin",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "21.03±1.37",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03249",
"func": "F0108",
"targ": null,
"compound": "D0991: methfuroxam",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03250",
"func": "F0108",
"targ": null,
"compound": "D0992: methisazone",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "21.51±9.04",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03251",
"func": "F0108",
"targ": null,
"compound": "D0197: Methoxychlor",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "27.72±10.98",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03252",
"func": "F0108",
"targ": null,
"compound": "D0993: methyl 2,4-dihydroxy-3,6-dimethylbenzoate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "30.57±28.43",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03253",
"func": "F0108",
"targ": null,
"compound": "D0994: methyl triclosan",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "45.86±14.67",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03254",
"func": "F0108",
"targ": null,
"compound": "D0995: methyl violet",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "1.73±0.00",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03255",
"func": "F0108",
"targ": null,
"compound": "D0996: methyldigoxin",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03256",
"func": "F0108",
"targ": null,
"compound": "D0199: Methylene Blue",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03257",
"func": "F0108",
"targ": null,
"compound": "D0997: methylene blue trihydrate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "7.29±7.49",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03258",
"func": "F0108",
"targ": null,
"compound": "D0998: methylsilanetriyl triacetate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03259",
"func": "F0108",
"targ": null,
"compound": "D0999: methyltrioctylammonium trifluoromethanesulfonate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "11.36±2.12",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03260",
"func": "F0108",
"targ": null,
"compound": "D1000: metochalcone",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "25.48±18.19",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03261",
"func": "F0108",
"targ": null,
"compound": "D1001: mgk-264",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "17.77±25.05",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03262",
"func": "F0108",
"targ": null,
"compound": "D1002: mifepristone",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03263",
"func": "F0108",
"targ": null,
"compound": "D1003: miripirium chloride",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "19.54±2.25",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03264",
"func": "F0108",
"targ": null,
"compound": "D1004: mk-2206",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03265",
"func": "F0108",
"targ": null,
"compound": "D1005: mometasone furoate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "13.96±1.14",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03266",
"func": "F0108",
"targ": null,
"compound": "D1006: montelukast sodium",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "24.08±9.54",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03267",
"func": "F0108",
"targ": null,
"compound": "D1007: n,n-diethylbenzene-1,4-diamine",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "31.62±0.00",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03268",
"func": "F0108",
"targ": null,
"compound": "D1008: n,n-dimethyl-p-phenylenediamine",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "21.66±15.72",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03269",
"func": "F0108",
"targ": null,
"compound": "D1009: n,nφ-diethylcarbanilide",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "13.11±16.35",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03270",
"func": "F0108",
"targ": null,
"compound": "D1010: natamycin",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03271",
"func": "F0108",
"targ": null,
"compound": "D1011: n-benzyl-6-ethoxy-4-oxo-1,4-dihydro-1,5-naphthyridine-3-carboxamide",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "24.04±16.59",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03272",
"func": "F0108",
"targ": null,
"compound": "D1012: n-cyclohexyl-4-methyl benzenesulfonamide",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "38.09±25.65",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03273",
"func": "F0108",
"targ": null,
"compound": "D1013: nelfinavir mesylate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "8.68±12.24",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03274",
"func": "F0108",
"targ": null,
"compound": "D0374: Niclosamide",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "0.44±0.27",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03275",
"func": "F0108",
"targ": null,
"compound": "D1014: niflumic acid",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "6.71±1.14",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
}
]
}
