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"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03332",
"func": "F0108",
"targ": null,
"compound": "D1066: proflavin hemisulfate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "11.60±5.45",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03333",
"func": "F0108",
"targ": null,
"compound": "D1067: proflavin hydrochloride",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "15.91±5.23",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03334",
"func": "F0108",
"targ": null,
"compound": "D1068: profluralin",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "25.06±35.43",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03335",
"func": "F0108",
"targ": null,
"compound": "D1069: propan-2-yl (2r,4s)-4-{acetyl[3,5-bis(trifluoromethyl)benzyl]amino}-2-ethyl-6-(trifluoromethyl)-3,4-dihydroquinoline-1(2h)-carboxylate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03336",
"func": "F0108",
"targ": null,
"compound": "D1070: propyl gallate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03337",
"func": "F0108",
"targ": null,
"compound": "D1071: propylparaben",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03338",
"func": "F0108",
"targ": null,
"compound": "D1072: proscillaridin",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03339",
"func": "F0108",
"targ": null,
"compound": "D1073: pyraclostrobin",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "9.04±1.89",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03340",
"func": "F0108",
"targ": null,
"compound": "D1074: pyridate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "50.45±8.18",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03341",
"func": "F0108",
"targ": null,
"compound": "D1075: pyrinuron",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "25.79±10.10",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03342",
"func": "F0108",
"targ": null,
"compound": "D1076: pyrvinium pamoate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "1.03±0.26",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03343",
"func": "F0108",
"targ": null,
"compound": "D1077: quercetin",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "15.14±6.79",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03344",
"func": "F0108",
"targ": null,
"compound": "D1078: quercetin dihydrate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "5.83±4.93",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03345",
"func": "F0108",
"targ": null,
"compound": "D1079: rac benidipine hydrochloride",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03346",
"func": "F0108",
"targ": null,
"compound": "D1080: rafoxanide",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "1.86±0.83",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03347",
"func": "F0108",
"targ": null,
"compound": "D1081: raloxifene",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "22.40±24.05",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03348",
"func": "F0108",
"targ": null,
"compound": "D1082: raloxifene hydrochloride",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "20.94±7.23",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03349",
"func": "F0108",
"targ": null,
"compound": "D0398: resveratrol",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03350",
"func": "F0108",
"targ": null,
"compound": "D0395: Rhein",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "11.58±4.85",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03351",
"func": "F0108",
"targ": null,
"compound": "D1083: riboflavin",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "31.27±8.72",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03352",
"func": "F0108",
"targ": null,
"compound": "D1084: rifampicin",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "6.15±2.20",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03353",
"func": "F0108",
"targ": null,
"compound": "D1085: rifapentine",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "0.62±0.55",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03354",
"func": "F0108",
"targ": null,
"compound": "D1086: rimonabant",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "17.45±2.83",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03355",
"func": "F0108",
"targ": null,
"compound": "D1087: rolicyclidine",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03356",
"func": "F0108",
"targ": null,
"compound": "D0229: Rotenone",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "0.20±0.30",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03357",
"func": "F0108",
"targ": null,
"compound": "D1088: salicylanilide",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "29.09±12.18",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03358",
"func": "F0108",
"targ": null,
"compound": "D1089: selenious acid",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "44.11±26.85",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03359",
"func": "F0108",
"targ": null,
"compound": "D1090: siduron",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "43.93±17.40",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03360",
"func": "F0108",
"targ": null,
"compound": "D1091: silwet l77",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "14.31±2.67",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03361",
"func": "F0108",
"targ": null,
"compound": "D0434: rapamycin",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "20.64±1.68",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03362",
"func": "F0108",
"targ": null,
"compound": "D1093: sodium (4-fluoro-2-{[(1s)-1-phenylpropyl]carbamoyl}phenyl)(quinolin-8-ylsulfonyl)azanide",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "35.85±20.20",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03363",
"func": "F0108",
"targ": null,
"compound": "D1094: sodium 2-phenylphenate tetrahydrate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03364",
"func": "F0108",
"targ": null,
"compound": "D1095: sodium bithionolate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03365",
"func": "F0108",
"targ": null,
"compound": "D1096: sodium warfarin",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "35.48±0.00",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03366",
"func": "F0108",
"targ": null,
"compound": "D1097: sofalcone",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "19.54±2.25",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03367",
"func": "F0108",
"targ": null,
"compound": "D1098: sorafenib",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "2.25±0.63",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03368",
"func": "F0108",
"targ": null,
"compound": "D1099: sp600125",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "21.13±2.91",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03369",
"func": "F0108",
"targ": null,
"compound": "D1100: spiclomazine hydrochloride",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": false
},
{
"rec_id": "RC03370",
"func": "F0108",
"targ": null,
"compound": "D1101: spiperone",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "2.92±0.24",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03371",
"func": "F0108",
"targ": null,
"compound": "D1102: su-5416",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "11.01±1.78",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03372",
"func": "F0108",
"targ": null,
"compound": "D1103: sulfanitran",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "19.54±2.25",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03373",
"func": "F0108",
"targ": null,
"compound": "D1104: surinabant",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "34.31±22.53",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03374",
"func": "F0108",
"targ": null,
"compound": "D1105: talniflumate",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "15.95±6.68",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
},
{
"rec_id": "RC03375",
"func": "F0108",
"targ": null,
"compound": "D1106: tamibarotene",
"paper": "163",
"func_act": "decrease",
"targ_act": "",
"dose": "9.06±6.66",
"time": "",
"method": "MMP assay",
"species": "rat",
"animal_model": "hepatocytes",
"criteria": "IC50",
"result": true
}
]
}
