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"dose": "3.43±1.47",
"time": "",
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"result": true
},
{
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},
{
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"compound": "D0001: Fluorouracil",
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"result": true
},
{
"rec_id": "RC03434",
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"targ": null,
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"targ_act": "",
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"time": "",
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"result": true
},
{
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"func": null,
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"time": "",
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"result": true
},
{
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"func": null,
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"dose": "",
"time": "",
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"animal_model": "",
"criteria": "",
"result": true
},
{
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"func": null,
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"compound": "D0221: Deguelin",
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"func_act": "",
"targ_act": "",
"dose": "",
"time": "",
"method": "",
"species": "",
"animal_model": "",
"criteria": "",
"result": true
},
{
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"func": null,
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"paper": "185",
"func_act": "",
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"dose": "",
"time": "",
"method": "",
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"animal_model": "",
"criteria": "",
"result": true
},
{
"rec_id": "RC03439",
"func": null,
"targ": "T004001",
"compound": "D0009: Antimycin A",
"paper": "185",
"func_act": "",
"targ_act": "",
"dose": "",
"time": "",
"method": "",
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"animal_model": "",
"criteria": "",
"result": true
},
{
"rec_id": "RC03440",
"func": null,
"targ": "T004001",
"compound": "D0516: stigmatellin",
"paper": "185",
"func_act": "",
"targ_act": "",
"dose": "",
"time": "",
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"species": "",
"animal_model": "",
"criteria": "",
"result": true
},
{
"rec_id": "RC03441",
"func": null,
"targ": "T001",
"compound": "D0205: MPTP",
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"func_act": "",
"targ_act": "",
"dose": "",
"time": "",
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"animal_model": "",
"criteria": "",
"result": true
},
{
"rec_id": "RC03442",
"func": null,
"targ": "T001",
"compound": "D0064: Haloperidol",
"paper": "185",
"func_act": "",
"targ_act": "",
"dose": "",
"time": "",
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"species": "",
"animal_model": "",
"criteria": "",
"result": true
},
{
"rec_id": "RC03443",
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"targ": null,
"compound": "D1372: colchicine",
"paper": "185",
"func_act": "",
"targ_act": "",
"dose": "",
"time": "",
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"animal_model": "",
"criteria": "",
"result": true
},
{
"rec_id": "RC03444",
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"targ": null,
"compound": "D0899: docetaxel",
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"func_act": "",
"targ_act": "",
"dose": "",
"time": "",
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"animal_model": "",
"criteria": "",
"result": true
},
{
"rec_id": "RC03445",
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"targ": null,
"compound": "D0030: Clofibrate",
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"func_act": "",
"targ_act": "",
"dose": "",
"time": "",
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"animal_model": "",
"criteria": "",
"result": true
},
{
"rec_id": "RC03446",
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"targ": null,
"compound": "D0005: Amiodarone",
"paper": "185",
"func_act": "",
"targ_act": "",
"dose": "",
"time": "",
"method": "",
"species": "",
"animal_model": "",
"criteria": "",
"result": true
},
{
"rec_id": "RC03447",
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"compound": "D0059: Fluoroacetate",
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"time": "",
"method": "",
"species": "",
"animal_model": "",
"criteria": "",
"result": true
},
{
"rec_id": "RC03449",
"func": "F030802",
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"dose": "",
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"result": true
},
{
"rec_id": "RC03450",
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"result": true
},
{
"rec_id": "RC03451",
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"targ": null,
"compound": "D0108: Rosiglitazone",
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"func_act": "affect",
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"result": true
},
{
"rec_id": "RC03452",
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"result": true
},
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"time": "",
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"animal_model": " C2C12 myoblasts",
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"result": true
},
{
"rec_id": "RC03456",
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"time": "",
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"animal_model": " C2C12 myoblasts",
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"result": true
},
{
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"time": "",
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"animal_model": " C2C12 myoblasts",
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"result": true
},
{
"rec_id": "RC03461",
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"compound": "D0021: Cerivastatin",
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"time": "",
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"animal_model": " C2C12 myoblasts",
"criteria": "",
"result": true
},
{
"rec_id": "RC03462",
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"time": "",
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"animal_model": " C2C12 myoblasts",
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"result": true
},
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"time": "",
"method": "measured ubiquinol:cytochrome c oxidoreductase activity in broken C2C12 mitochondria after acute statin exposure at a fixed concentration for all compounds",
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"animal_model": " C2C12 myoblasts",
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"result": true
},
{
"rec_id": "RC03602",
"func": "F0402",
"targ": null,
"compound": "D0194: Menadione",
"paper": "218",
"func_act": "decrease",
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"dose": "10 μM",
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"animal_model": "",
"criteria": "",
"result": true
},
{
"rec_id": "RC03612",
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"compound": "D0069: Indomethacin",
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"func_act": "",
"targ_act": "",
"dose": "",
"time": "",
"method": "",
"species": "",
"animal_model": "",
"criteria": "",
"result": true
},
{
"rec_id": "RC03464",
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"animal_model": " C2C12 myoblasts",
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"result": true
},
{
"rec_id": "RC03465",
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"time": "",
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"result": true
},
{
"rec_id": "RC03467",
"func": null,
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"compound": "D0069: Indomethacin",
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"func_act": "",
"targ_act": "inhibitor",
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"time": "",
"method": "",
"species": "",
"animal_model": "",
"criteria": "",
"result": true
},
{
"rec_id": "RC03468",
"func": null,
"targ": "T181",
"compound": "D0043: Doxorubicin",
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"func_act": "",
"targ_act": "inhibitor",
"dose": "",
"time": "",
"method": "",
"species": "",
"animal_model": "",
"criteria": "",
"result": true
},
{
"rec_id": "RC03469",
"func": null,
"targ": "T181",
"compound": "D0262: Diazoxide",
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"func_act": "",
"targ_act": "inhibitor",
"dose": "",
"time": "",
"method": "",
"species": "",
"animal_model": "",
"criteria": "",
"result": true
},
{
"rec_id": "RC03470",
"func": null,
"targ": "T181",
"compound": "D0262: Diazoxide",
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"func_act": "",
"targ_act": "inhibitor",
"dose": "",
"time": "",
"method": "The activity of the rnitochondrial glycerol phosphate dehydrogenase was assayed with a timed assay using iodonitrotetrazolium violet as an electron acceptor and in a continuous spectrophotometric assay using dichloroindophenol as an electron acceptor. acceptor. Glycerol phosphate oxidation by islet intact mitochondria was estimated from the tritiated water released from [2- 3H]glycerol phosphate",
"species": "",
"animal_model": "Homogenates of isolated pancreatic islets; homogenates of whole pancreas, liver, heart, or skeletal muscle ",
"criteria": "",
"result": true
},
{
"rec_id": "RC03471",
"func": "F02110304",
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"compound": "D0262: Diazoxide",
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"time": "",
"method": "flow cytometry and quantitative image analysis of cells stained with fluorescent DC indicators.",
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"animal_model": "Primary Culture of Neonatal Rat Cardiac Ventricular Myocytes",
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"result": true
},
{
"rec_id": "RC03472",
"func": "F02110304",
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"compound": "D0295: Pinacidil",
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"func_act": "affect",
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"time": "",
"method": "",
"species": "",
"animal_model": "",
"criteria": "",
"result": true
},
{
"rec_id": "RC03473",
"func": "F02110304",
"targ": "T208",
"compound": "D0245: 5-Hydroxydecanoate",
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"func_act": "affect",
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"dose": "500mmol/L",
"time": "",
"method": "flow cytometry and quantitative image analysis of cells stained with fluorescent DC indicators.",
"species": "",
"animal_model": "Primary Culture of Neonatal Rat Cardiac Ventricular Myocytes",
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"result": true
},
{
"rec_id": "RC03474",
"func": "F02110304",
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"compound": "D0265: Glibenclamide",
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"func_act": "affect",
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"dose": "",
"time": "",
"method": "",
"species": "",
"animal_model": "",
"criteria": "",
"result": true
},
{
"rec_id": "RC03475",
"func": "F02060101",
"targ": null,
"compound": "D0245: 5-Hydroxydecanoate",
"paper": "189",
"func_act": "decrease",
"targ_act": "",
"dose": "100 μm",
"time": "",
"method": "",
"species": "",
"animal_model": "",
"criteria": "",
"result": true
},
{
"rec_id": "RC03476",
"func": "F02110304",
"targ": "T208",
"compound": "D0265: Glibenclamide",
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"func_act": "affect",
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"dose": "K1/2 values 1-6 microM",
"time": "",
"method": "",
"species": "",
"animal_model": " heart and liver mitochondria from rat",
"criteria": "",
"result": true
},
{
"rec_id": "RC03477",
"func": "F02060101",
"targ": null,
"compound": "D0245: 5-Hydroxydecanoate",
"paper": "190",
"func_act": "decrease",
"targ_act": "",
"dose": "K1/2 values 45-75 microM",
"time": "",
"method": "",
"species": "",
"animal_model": " heart and liver mitochondria from rat",
"criteria": "",
"result": true
},
{
"rec_id": "RC03478",
"func": "F050401",
"targ": "T181",
"compound": "D1275: glyceraldehyde 3-phosphate",
"paper": "162",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "2.5mM",
"time": "",
"method": "",
"species": "",
"animal_model": "",
"criteria": "",
"result": true
},
{
"rec_id": "RC03479",
"func": "F050401",
"targ": "T181",
"compound": "D1276: dihydroxyacetone phosphate",
"paper": "162",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "",
"time": "",
"method": "",
"species": "",
"animal_model": "",
"criteria": "",
"result": true
},
{
"rec_id": "RC03480",
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"targ": "T181",
"compound": "D1275: glyceraldehyde 3-phosphate",
"paper": "162",
"func_act": "decrease",
"targ_act": "inhibitor",
"dose": "2.5mM",
"time": "",
"method": "",
"species": "",
"animal_model": "",
"criteria": "",
"result": true
}
]
}
