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{
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"targ": null,
"compound": "D0005: Amiodarone",
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"targ_act": "",
"dose": "50 µM",
"time": "1 hour",
"method": "High-content screening assay",
"species": "Human",
"animal_model": "HepG2",
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"result": true
},
{
"rec_id": "RC04679",
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"targ": null,
"compound": "D0005: Amiodarone",
"paper": "306",
"func_act": "Increase",
"targ_act": "",
"dose": "5 µM ",
"time": "1 hour",
"method": "High-content screening assay",
"species": "Human",
"animal_model": "HepG2",
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"result": true
},
{
"rec_id": "RC04680",
"func": "F0108",
"targ": null,
"compound": "D0024: Chlorpromazine",
"paper": "306",
"func_act": "Decrease",
"targ_act": "",
"dose": "100 µM",
"time": "1 hour",
"method": "High-content screening assay",
"species": "Human",
"animal_model": "HepG2",
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"result": true
},
{
"rec_id": "RC04681",
"func": "F0108",
"targ": null,
"compound": "D0261: Cyclosporin A",
"paper": "306",
"func_act": "Increase",
"targ_act": "",
"dose": "5 µM",
"time": "1 hour",
"method": "High-content screening assay",
"species": "Human",
"animal_model": "HepG2",
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"result": true
},
{
"rec_id": "RC04682",
"func": "F0108",
"targ": null,
"compound": "D0461: imipramine",
"paper": "306",
"func_act": "Decrease",
"targ_act": "",
"dose": "50 µM",
"time": "1 hour",
"method": "High-content screening assay",
"species": "Human",
"animal_model": "HepG2",
"criteria": "MEC",
"result": true
},
{
"rec_id": "RC04683",
"func": "F0108",
"targ": null,
"compound": "D1434: Maprotiline",
"paper": "306",
"func_act": "Decrease",
"targ_act": "",
"dose": "5 µM",
"time": "1 hour",
"method": "High-content screening assay",
"species": "Human",
"animal_model": "HepG2",
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"result": true
},
{
"rec_id": "RC04684",
"func": "F0108",
"targ": null,
"compound": "D0229: Rotenone",
"paper": "306",
"func_act": "Decrease",
"targ_act": "",
"dose": "5 µM",
"time": "1 hour",
"method": "High-content screening assay",
"species": "Human",
"animal_model": "HepG2",
"criteria": "MEC",
"result": true
},
{
"rec_id": "RC04685",
"func": "F0108",
"targ": null,
"compound": "D0116: Tamoxifen",
"paper": "306",
"func_act": "Decrease",
"targ_act": "",
"dose": "100 µM",
"time": "1 hour",
"method": "High-content screening assay",
"species": "Human",
"animal_model": "HepG2",
"criteria": "MEC",
"result": true
},
{
"rec_id": "RC04686",
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"compound": "D0124: Troglitazone",
"paper": "306",
"func_act": "Decrease",
"targ_act": "",
"dose": "10 µM",
"time": "1 hour",
"method": "High-content screening assay",
"species": "Human",
"animal_model": "HepG2",
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"result": true
},
{
"rec_id": "RC04687",
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"targ": null,
"compound": "D1379: atorvastatin",
"paper": "306",
"func_act": "Increase",
"targ_act": "",
"dose": "100 µM",
"time": "1 hour",
"method": "High-content screening assay",
"species": "Human",
"animal_model": "HepG2",
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"result": true
},
{
"rec_id": "RC04688",
"func": "F0108",
"targ": null,
"compound": "D0021: Cerivastatin",
"paper": "306",
"func_act": "Decrease",
"targ_act": "",
"dose": "50 µM",
"time": "1 hour",
"method": "High-content screening assay",
"species": "Human",
"animal_model": "HepG2",
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"result": true
},
{
"rec_id": "RC04689",
"func": "F0108",
"targ": null,
"compound": "D0945: fluvastatin",
"paper": "306",
"func_act": "Affect",
"targ_act": "",
"dose": ">100 µM",
"time": "1 hour",
"method": "High-content screening assay",
"species": "Human",
"animal_model": "HepG2",
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"result": false
},
{
"rec_id": "RC04690",
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"targ": null,
"compound": "D0467: lovastatin",
"paper": "306",
"func_act": "Decrease",
"targ_act": "",
"dose": "100 µM",
"time": "1 hour",
"method": "High-content screening assay",
"species": "Human",
"animal_model": "HepG2",
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"result": true
},
{
"rec_id": "RC04691",
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"compound": "D0442: pravastatin",
"paper": "306",
"func_act": "Affect",
"targ_act": "",
"dose": ">100 µM",
"time": "1 hour",
"method": "High-content screening assay",
"species": "Human",
"animal_model": "HepG2",
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"result": false
},
{
"rec_id": "RC04692",
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"targ": null,
"compound": "D0111: Simvastatin",
"paper": "306",
"func_act": "Decrease",
"targ_act": "",
"dose": "50 µM",
"time": "1 hour",
"method": "High-content screening assay",
"species": "Human",
"animal_model": "HepG2",
"criteria": "MEC",
"result": true
},
{
"rec_id": "RC04693",
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"targ": null,
"compound": "D0128: Zidovudine",
"paper": "307",
"func_act": "increase",
"targ_act": "",
"dose": "",
"time": "",
"method": "",
"species": "",
"animal_model": "",
"criteria": "",
"result": true
},
{
"rec_id": "RC04694",
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"targ": null,
"compound": "D1438: Acyclovir",
"paper": "307",
"func_act": "increase",
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"dose": "",
"time": "",
"method": "",
"species": "",
"animal_model": "",
"criteria": "",
"result": true
},
{
"rec_id": "RC04695",
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"targ": null,
"compound": "D1439: Ganciclovir",
"paper": "307",
"func_act": "increase",
"targ_act": "",
"dose": "",
"time": "",
"method": "",
"species": "",
"animal_model": "",
"criteria": "",
"result": true
},
{
"rec_id": "RC04696",
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"targ": null,
"compound": "D0127: Zalcitabine",
"paper": "307",
"func_act": "increase",
"targ_act": "",
"dose": "",
"time": "",
"method": "",
"species": "",
"animal_model": "",
"criteria": "",
"result": true
},
{
"rec_id": "RC04697",
"func": "F0604",
"targ": null,
"compound": "D0128: Zidovudine",
"paper": "307",
"func_act": "decrease",
"targ_act": "",
"dose": "",
"time": "",
"method": "",
"species": "",
"animal_model": "",
"criteria": "",
"result": true
},
{
"rec_id": "RC04698",
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"targ": null,
"compound": "D1438: Acyclovir",
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"targ_act": "",
"dose": "",
"time": "",
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"result": true
},
{
"rec_id": "RC04699",
"func": "F0604",
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"compound": "D1439: Ganciclovir",
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"func_act": "decrease",
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"dose": "",
"time": "",
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"criteria": "",
"result": true
},
{
"rec_id": "RC04700",
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"compound": "D0127: Zalcitabine",
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"targ_act": "",
"dose": "",
"time": "",
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"result": true
},
{
"rec_id": "RC04701",
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"targ": "T387",
"compound": "D0128: Zidovudine",
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"func_act": "Increase",
"targ_act": "increase",
"dose": "",
"time": "",
"method": "",
"species": "",
"animal_model": "",
"criteria": "",
"result": true
},
{
"rec_id": "RC04702",
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"targ": "T387",
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"dose": "",
"time": "",
"method": "",
"species": "",
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"result": true
},
{
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"targ": "T387",
"compound": "D1439: Ganciclovir",
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"dose": "",
"time": "",
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"result": true
},
{
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"time": "",
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"result": true
},
{
"rec_id": "RC04705",
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"targ": null,
"compound": "D0128: Zidovudine",
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"func_act": "abnormalize",
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"dose": "",
"time": "",
"method": "",
"species": "",
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"criteria": "",
"result": true
},
{
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"compound": "D1438: Acyclovir",
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"dose": "",
"time": "",
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"result": true
},
{
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"dose": "",
"time": "",
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"criteria": "",
"result": true
},
{
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"dose": "",
"time": "",
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"result": true
},
{
"rec_id": "RC04709",
"func": null,
"targ": "T005",
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"time": "",
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"result": true
},
{
"rec_id": "RC04710",
"func": null,
"targ": "T005",
"compound": "D1438: Acyclovir",
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"time": "",
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"result": true
},
{
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"func_act": "",
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"time": "",
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"result": true
},
{
"rec_id": "RC04712",
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"time": "",
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"result": true
},
{
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"func": null,
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"time": "",
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"result": true
},
{
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"time": "",
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"result": true
},
{
"rec_id": "RC04715",
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"compound": "D1439: Ganciclovir",
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"func_act": "",
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"time": "",
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"result": true
},
{
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"time": "",
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"result": true
},
{
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"compound": "D0128: Zidovudine",
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"time": "",
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"result": true
},
{
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"time": "",
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"result": true
},
{
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"compound": "D1439: Ganciclovir",
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"result": true
},
{
"rec_id": "RC04720",
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"result": true
},
{
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"time": "",
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"result": true
},
{
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"time": "",
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"result": true
},
{
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"compound": "D0432: tetracyclines",
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"dose": "",
"time": "",
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"result": true
},
{
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"compound": "D0432: tetracyclines",
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"time": "",
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"result": true
},
{
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"result": true
},
{
"rec_id": "RC04726",
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"compound": "D0259: Ciprofloxacin",
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"dose": "",
"time": "",
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"result": true
},
{
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"result": true
},
{
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"compound": "D0259: Ciprofloxacin",
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"time": "",
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"result": true
},
{
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"time": "",
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"result": true
},
{
"rec_id": "RC04730",
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"compound": "D0259: Ciprofloxacin",
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"time": "",
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"result": true
},
{
"rec_id": "RC04731",
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"result": true
}
]
}
