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            "dose": "100 nmol/mg mitochondrial protein",
            "time": "",
            "method": "State 3 respiration ( 96-well plate format using a phosphorescent oxygen-sensitive probe MitoXpress)",
            "species": "rat",
            "animal_model": "isolated rat liver mitochondria",
            "criteria": "IC50 (nmol/mg mitochondrial protein)",
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        },
        {
            "rec_id": "RC04785",
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            "dose": "100 nmol/mg mitochondrial protein",
            "time": "",
            "method": "State 3 respiration ( 96-well plate format using a phosphorescent oxygen-sensitive probe MitoXpress)",
            "species": "rat",
            "animal_model": "isolated rat liver mitochondria",
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        },
        {
            "rec_id": "RC04786",
            "func": "F02010103",
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            "compound": "D0038: Diclofenac",
            "paper": "40",
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            "targ_act": "",
            "dose": "100 nmol/mg mitochondrial protein",
            "time": "",
            "method": "State 3 respiration ( 96-well plate format using a phosphorescent oxygen-sensitive probe MitoXpress)",
            "species": "rat",
            "animal_model": "isolated rat liver mitochondria",
            "criteria": "IC50 (nmol/mg mitochondrial protein)",
            "result": false
        },
        {
            "rec_id": "RC04787",
            "func": "F02010103",
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            "compound": "D0115: Sulindac",
            "paper": "40",
            "func_act": "inhibit",
            "targ_act": "",
            "dose": "100 nmol/mg mitochondrial protein",
            "time": "",
            "method": "State 3 respiration ( 96-well plate format using a phosphorescent oxygen-sensitive probe MitoXpress)",
            "species": "rat",
            "animal_model": "isolated rat liver mitochondria",
            "criteria": "IC50 (nmol/mg mitochondrial protein)",
            "result": false
        },
        {
            "rec_id": "RC04788",
            "func": "F02010103",
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            "func_act": "inhibit",
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            "dose": "39.8 ± 2.9",
            "time": "",
            "method": "State 3 respiration ( 96-well plate format using a phosphorescent oxygen-sensitive probe MitoXpress)",
            "species": "rat",
            "animal_model": "isolated rat liver mitochondria",
            "criteria": "IC50 (nmol/mg mitochondrial protein)",
            "result": true
        },
        {
            "rec_id": "RC04789",
            "func": "F02010103",
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            "compound": "D1452: Sulindac sulfone",
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            "targ_act": "",
            "dose": "100 nmol/mg mitochondrial protein",
            "time": "",
            "method": "State 3 respiration ( 96-well plate format using a phosphorescent oxygen-sensitive probe MitoXpress)",
            "species": "rat",
            "animal_model": "isolated rat liver mitochondria",
            "criteria": "IC50 (nmol/mg mitochondrial protein)",
            "result": false
        },
        {
            "rec_id": "RC04790",
            "func": "F02010103",
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            "compound": "D0092: Nimesulide",
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            "targ_act": "",
            "dose": "100 nmol/mg mitochondrial protein",
            "time": "",
            "method": "State 3 respiration ( 96-well plate format using a phosphorescent oxygen-sensitive probe MitoXpress)",
            "species": "rat",
            "animal_model": "isolated rat liver mitochondria",
            "criteria": "IC50 (nmol/mg mitochondrial protein)",
            "result": false
        },
        {
            "rec_id": "RC04791",
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            "compound": "D0057: Flufenamic Acid",
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            "func_act": "induce",
            "targ_act": "",
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            "time": "24hr",
            "method": "DNA damage 153 induction  (GADD153 antibodies) for ER-stress induced apoptosis",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": true
        },
        {
            "rec_id": "RC04792",
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            "func_act": "induce",
            "targ_act": "",
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            "time": "24hr",
            "method": "DNA damage 153 induction  (GADD153 antibodies) for ER-stress induced apoptosis",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": true
        },
        {
            "rec_id": "RC04793",
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            "compound": "D0078: Mefenamic acid",
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            "func_act": "induce",
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            "dose": "61",
            "time": "24hr",
            "method": "DNA damage 153 induction  (GADD153 antibodies) for ER-stress induced apoptosis",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": true
        },
        {
            "rec_id": "RC04794",
            "func": "F070106",
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            "compound": "D0079: Meloxicam",
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            "func_act": "induce",
            "targ_act": "",
            "dose": "153",
            "time": "24hr",
            "method": "DNA damage 153 induction  (GADD153 antibodies) for ER-stress induced apoptosis",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": true
        },
        {
            "rec_id": "RC04795",
            "func": "F070106",
            "targ": null,
            "compound": "D1450: Sudoxicam",
            "paper": "40",
            "func_act": "induce",
            "targ_act": "",
            "dose": "223",
            "time": "24hr",
            "method": "DNA damage 153 induction  (GADD153 antibodies) for ER-stress induced apoptosis",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": true
        },
        {
            "rec_id": "RC04796",
            "func": "F070106",
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            "compound": "D0099: Piroxicam",
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            "func_act": "induce",
            "targ_act": "",
            "dose": "610",
            "time": "24hr",
            "method": "DNA damage 153 induction  (GADD153 antibodies) for ER-stress induced apoptosis",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": true
        },
        {
            "rec_id": "RC04797",
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            "targ": null,
            "compound": "D0040: Diflunisal",
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            "func_act": "induce",
            "targ_act": "",
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            "time": "24hr",
            "method": "DNA damage 153 induction  (GADD153 antibodies) for ER-stress induced apoptosis",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": true
        },
        {
            "rec_id": "RC04798",
            "func": "F070106",
            "targ": null,
            "compound": "D0010: Acetylsalicylic acid",
            "paper": "40",
            "func_act": "induce",
            "targ_act": "",
            "dose": "NR",
            "time": "24hr",
            "method": "DNA damage 153 induction  (GADD153 antibodies) for ER-stress induced apoptosis",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": false
        },
        {
            "rec_id": "RC04799",
            "func": "F070106",
            "targ": null,
            "compound": "D0038: Diclofenac",
            "paper": "40",
            "func_act": "induce",
            "targ_act": "",
            "dose": "51",
            "time": "24hr",
            "method": "DNA damage 153 induction  (GADD153 antibodies) for ER-stress induced apoptosis",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": true
        },
        {
            "rec_id": "RC04800",
            "func": "F070106",
            "targ": null,
            "compound": "D0115: Sulindac",
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            "func_act": "induce",
            "targ_act": "",
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            "time": "24hr",
            "method": "DNA damage 153 induction  (GADD153 antibodies) for ER-stress induced apoptosis",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": false
        },
        {
            "rec_id": "RC04801",
            "func": "F070106",
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            "compound": "D1451: Sulindac sulfide",
            "paper": "40",
            "func_act": "induce",
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            "dose": "53",
            "time": "24hr",
            "method": "DNA damage 153 induction  (GADD153 antibodies) for ER-stress induced apoptosis",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": true
        },
        {
            "rec_id": "RC04802",
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            "func_act": "induce",
            "targ_act": "",
            "dose": "NR",
            "time": "24hr",
            "method": "DNA damage 153 induction  (GADD153 antibodies) for ER-stress induced apoptosis",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": false
        },
        {
            "rec_id": "RC04803",
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            "targ": null,
            "compound": "D0092: Nimesulide",
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            "func_act": "induce",
            "targ_act": "",
            "dose": "8",
            "time": "24hr",
            "method": "DNA damage 153 induction  (GADD153 antibodies) for ER-stress induced apoptosis",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": true
        },
        {
            "rec_id": "RC04804",
            "func": "F070105",
            "targ": null,
            "compound": "D0057: Flufenamic Acid",
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            "func_act": "induce",
            "targ_act": "",
            "dose": "70",
            "time": "24hr",
            "method": "cytochrome c release (anti-cytochrome c antibody )",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": true
        },
        {
            "rec_id": "RC04805",
            "func": "F070105",
            "targ": null,
            "compound": "D0122: Tolfenamic Acid",
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            "func_act": "induce",
            "targ_act": "",
            "dose": "75",
            "time": "24hr",
            "method": "cytochrome c release (anti-cytochrome c antibody )",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": true
        },
        {
            "rec_id": "RC04806",
            "func": "F070105",
            "targ": null,
            "compound": "D0078: Mefenamic acid",
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            "func_act": "induce",
            "targ_act": "",
            "dose": "277",
            "time": "24hr",
            "method": "cytochrome c release (anti-cytochrome c antibody )",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": true
        },
        {
            "rec_id": "RC04807",
            "func": "F070105",
            "targ": null,
            "compound": "D0079: Meloxicam",
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            "func_act": "induce",
            "targ_act": "",
            "dose": "245",
            "time": "24hr",
            "method": "cytochrome c release (anti-cytochrome c antibody )",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": true
        },
        {
            "rec_id": "RC04808",
            "func": "F070105",
            "targ": null,
            "compound": "D1450: Sudoxicam",
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            "func_act": "induce",
            "targ_act": "",
            "dose": "282",
            "time": "24hr",
            "method": "cytochrome c release (anti-cytochrome c antibody )",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": true
        },
        {
            "rec_id": "RC04809",
            "func": "F070105",
            "targ": null,
            "compound": "D0099: Piroxicam",
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            "func_act": "induce",
            "targ_act": "",
            "dose": "598",
            "time": "24hr",
            "method": "cytochrome c release (anti-cytochrome c antibody )",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": true
        },
        {
            "rec_id": "RC04810",
            "func": "F070105",
            "targ": null,
            "compound": "D0040: Diflunisal",
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            "func_act": "induce",
            "targ_act": "",
            "dose": "79",
            "time": "24hr",
            "method": "cytochrome c release (anti-cytochrome c antibody )",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": true
        },
        {
            "rec_id": "RC04811",
            "func": "F070105",
            "targ": null,
            "compound": "D0010: Acetylsalicylic acid",
            "paper": "40",
            "func_act": "induce",
            "targ_act": "",
            "dose": "NR",
            "time": "24hr",
            "method": "cytochrome c release (anti-cytochrome c antibody )",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": false
        },
        {
            "rec_id": "RC04812",
            "func": "F070105",
            "targ": null,
            "compound": "D0038: Diclofenac",
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            "func_act": "induce",
            "targ_act": "",
            "dose": "197",
            "time": "24hr",
            "method": "cytochrome c release (anti-cytochrome c antibody )",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": true
        },
        {
            "rec_id": "RC04813",
            "func": "F070105",
            "targ": null,
            "compound": "D0115: Sulindac",
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            "func_act": "induce",
            "targ_act": "",
            "dose": "NR",
            "time": "24hr",
            "method": "cytochrome c release (anti-cytochrome c antibody )",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": false
        },
        {
            "rec_id": "RC04814",
            "func": "F070105",
            "targ": null,
            "compound": "D1451: Sulindac sulfide",
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            "func_act": "induce",
            "targ_act": "",
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            "time": "24hr",
            "method": "cytochrome c release (anti-cytochrome c antibody )",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": true
        },
        {
            "rec_id": "RC04815",
            "func": "F070105",
            "targ": null,
            "compound": "D1452: Sulindac sulfone",
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            "func_act": "induce",
            "targ_act": "",
            "dose": "NR",
            "time": "24hr",
            "method": "cytochrome c release (anti-cytochrome c antibody )",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": false
        },
        {
            "rec_id": "RC04816",
            "func": "F070105",
            "targ": null,
            "compound": "D0092: Nimesulide",
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            "func_act": "induce",
            "targ_act": "",
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            "time": "24hr",
            "method": "cytochrome c release (anti-cytochrome c antibody )",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": true
        },
        {
            "rec_id": "RC04817",
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            "targ": null,
            "compound": "D0057: Flufenamic Acid",
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            "func_act": "accumulation",
            "targ_act": "",
            "dose": "146",
            "time": "24hr",
            "method": "LipidTox, for neutral lipid accumulation, to evaluate lipid content.",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": true
        },
        {
            "rec_id": "RC04818",
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            "targ": null,
            "compound": "D0122: Tolfenamic Acid",
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            "targ_act": "",
            "dose": "83.1",
            "time": "24hr",
            "method": "LipidTox, for neutral lipid accumulation, to evaluate lipid content.",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": true
        },
        {
            "rec_id": "RC04819",
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            "compound": "D0078: Mefenamic acid",
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            "targ_act": "",
            "dose": "161",
            "time": "24hr",
            "method": "LipidTox, for neutral lipid accumulation, to evaluate lipid content.",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": true
        },
        {
            "rec_id": "RC04820",
            "func": "F0206",
            "targ": null,
            "compound": "D0079: Meloxicam",
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            "func_act": "accumulation",
            "targ_act": "",
            "dose": "> 500",
            "time": "24hr",
            "method": "LipidTox, for neutral lipid accumulation, to evaluate lipid content.",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": true
        },
        {
            "rec_id": "RC04822",
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            "compound": "D0099: Piroxicam",
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            "func_act": "accumulation",
            "targ_act": "",
            "dose": "728",
            "time": "24hr",
            "method": "LipidTox, for neutral lipid accumulation, to evaluate lipid content.",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": true
        },
        {
            "rec_id": "RC04823",
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            "targ": null,
            "compound": "D0040: Diflunisal",
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            "targ_act": "",
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            "time": "24hr",
            "method": "LipidTox, for neutral lipid accumulation, to evaluate lipid content.",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": true
        },
        {
            "rec_id": "RC04824",
            "func": "F0206",
            "targ": null,
            "compound": "D0010: Acetylsalicylic acid",
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            "targ_act": "",
            "dose": "NR",
            "time": "24hr",
            "method": "LipidTox, for neutral lipid accumulation, to evaluate lipid content.",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": false
        },
        {
            "rec_id": "RC04825",
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            "targ": null,
            "compound": "D0038: Diclofenac",
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            "targ_act": "",
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            "time": "24hr",
            "method": "LipidTox, for neutral lipid accumulation, to evaluate lipid content.",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": true
        },
        {
            "rec_id": "RC04826",
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            "targ": null,
            "compound": "D0115: Sulindac",
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            "func_act": "accumulation",
            "targ_act": "",
            "dose": "NR",
            "time": "24hr",
            "method": "LipidTox, for neutral lipid accumulation, to evaluate lipid content.",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": false
        },
        {
            "rec_id": "RC04827",
            "func": "F0206",
            "targ": null,
            "compound": "D1451: Sulindac sulfide",
            "paper": "40",
            "func_act": "accumulation",
            "targ_act": "",
            "dose": "78",
            "time": "24hr",
            "method": "LipidTox, for neutral lipid accumulation, to evaluate lipid content.",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": true
        },
        {
            "rec_id": "RC04828",
            "func": "F0206",
            "targ": null,
            "compound": "D1452: Sulindac sulfone",
            "paper": "40",
            "func_act": "accumulation",
            "targ_act": "",
            "dose": "NR",
            "time": "24hr",
            "method": "LipidTox, for neutral lipid accumulation, to evaluate lipid content.",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": false
        },
        {
            "rec_id": "RC04829",
            "func": "F0206",
            "targ": null,
            "compound": "D0092: Nimesulide",
            "paper": "40",
            "func_act": "accumulation",
            "targ_act": "",
            "dose": "29",
            "time": "24hr",
            "method": "LipidTox, for neutral lipid accumulation, to evaluate lipid content.",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": true
        },
        {
            "rec_id": "RC04830",
            "func": "F01",
            "targ": null,
            "compound": "D0057: Flufenamic Acid",
            "paper": "40",
            "func_act": "decrease",
            "targ_act": "",
            "dose": "129",
            "time": "24hr",
            "method": "tetramethylrhodamine ethyl ester (TMRE)",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": true
        },
        {
            "rec_id": "RC04831",
            "func": "F01",
            "targ": null,
            "compound": "D0122: Tolfenamic Acid",
            "paper": "40",
            "func_act": "decrease",
            "targ_act": "",
            "dose": "122",
            "time": "24hr",
            "method": "tetramethylrhodamine ethyl ester (TMRE)",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": true
        },
        {
            "rec_id": "RC04832",
            "func": "F01",
            "targ": null,
            "compound": "D0078: Mefenamic acid",
            "paper": "40",
            "func_act": "decrease",
            "targ_act": "",
            "dose": "376",
            "time": "24hr",
            "method": "tetramethylrhodamine ethyl ester (TMRE)",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": true
        },
        {
            "rec_id": "RC04833",
            "func": "F01",
            "targ": null,
            "compound": "D0079: Meloxicam",
            "paper": "40",
            "func_act": "decrease",
            "targ_act": "",
            "dose": "382",
            "time": "24hr",
            "method": "tetramethylrhodamine ethyl ester (TMRE)",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": true
        },
        {
            "rec_id": "RC04834",
            "func": "F01",
            "targ": null,
            "compound": "D1450: Sudoxicam",
            "paper": "40",
            "func_act": "decrease",
            "targ_act": "",
            "dose": "487",
            "time": "24hr",
            "method": "tetramethylrhodamine ethyl ester (TMRE)",
            "species": "rat",
            "animal_model": "hepatocytes",
            "criteria": "AC50 (μM)",
            "result": true
        }
    ]
}