Drug

D0017 | Butacaine

Molecular Formula C18H30N2O2
Molecular Weight 306.4
Structure
Description local anesthetic

Organism Test type Route Dose (normalized dose) Effect Source
mouse LDLo subcutaneous 50mg/kg (50mg/kg) Journal of the American Chemical Society. Vol. 61, Pg. 3562, 1939.
cat LDLo intravenous 15mg/kg (15mg/kg) American Journal of Physiology. Vol. 68, Pg. 110, 1924.
mouse LDLo subcutaneous 100mg/kg (100mg/kg) Journal of Pharmacology and Experimental Therapeutics. Vol. 24, Pg. 167, 1925.
dog LDLo subcutaneous 55mg/kg (55mg/kg) Physiological Reviews. Vol. 12, Pg. 190, 1932.
rat LDLo subcutaneous 197mg/kg (197mg/kg) Physiological Reviews. Vol. 12, Pg. 190, 1932.
mouse LDLo intravenous 12mg/kg (12mg/kg) Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 39, Pg. 4, 1950.
bird - wild LD50 oral 100mg/kg (100mg/kg) Toxicology and Applied Pharmacology. Vol. 21, Pg. 315, 1972.
rabbit LDLo subcutaneous 50mg/kg (50mg/kg) Journal of Pharmacology and Experimental Therapeutics. Vol. 24, Pg. 167, 1925.
frog LDLo intraspinal 30mg/kg (30mg/kg) Journal of Pharmacology and Experimental Therapeutics. Vol. 45, Pg. 291, 1932.
guinea pig LDLo subcutaneous 45mg/kg (45mg/kg) Journal of Pharmacology and Experimental Therapeutics. Vol. 62, Pg. 69, 1938.
mouse LD50 intraperitoneal 80mg/kg (80mg/kg) British Journal of Pharmacology and Chemotherapy. Vol. 1, Pg. 90, 1946.
rat LDLo intravenous 7500ug/kg (7.5mg/kg) Physiological Reviews. Vol. 12, Pg. 190, 1932.
cat LDLo subcutaneous 30mg/kg (30mg/kg) Journal of Pharmacology and Experimental Therapeutics. Vol. 24, Pg. 167, 1925.
rabbit LDLo intravenous 12mg/kg (12mg/kg) Physiological Reviews. Vol. 12, Pg. 190, 1932.
mouse LD50 intravenous 12mg/kg (12mg/kg) Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 40, Pg. 373, 1951.
rat LDLo subcutaneous 150mg/kg (150mg/kg) Journal of Pharmacology and Experimental Therapeutics. Vol. 24, Pg. 167, 1925.


  • (3-di-N-Butylaminopropyl)-p-aminobenzoate 1-PROPANOL, 3-(DIBUTYLAMINO)-, p-AMINOBENZOATE (ESTER) 1-Propanol, 3-(dibutylamino)-, 1-(4-aminobenzoate)
    1-Propanol, 3-(dibutylamino)-, 4-aminobenzoate 1-Propanol, 3-(dibutylamino)-, 4-aminobenzoate (ester) 1-Propanol, 3-(dibutylamino)-, p-aminobenzoate
    149-16-6 2290AH 3-(Dibutylamino)-1-propanol p-aminobenzoate
    3-(Dibutylamino)propyl 4-aminobenzoate 3-(Dibutylamino)propyl 4-aminobenzoate # 3-(p-Aminobenzoxy)-1-di-n-butylaminopropane
    3-Dibutylaminopropyl p-aminobenzoate 4-aminobenzoic acid 3-(dibutylamino)propyl ester AB00052382
    AB00052382_15 AB00052382_16 AKOS024374899
    API0015124 BDBM50225491 BPBio1_000861
    BRD-K99622919-001-05-7 BRD-K99622919-001-15-6 BRN 2135378
    BSPBio_000781 BSPBio_003543 Butacaina
    Butacaina [INN-Spanish] Butacaine [INN:BAN] Butacaine sulphate
    Butacainum Butacainum [INN-Latin] C18H30N2O2
    CAS-149-16-6 CCG-39371 CHEBI:94820
    CHEMBL129529 CS-4504 CTK8F8367
    DSSTox_CID_25300 DSSTox_GSID_45300 DSSTox_RID_80789
    DTXSID3045300 DivK1c_000864 EINECS 205-734-7
    HMS1570H03 HMS1922K10 HMS2093K17
    HMS2097H03 HMS2230J20 HMS3371O14
    HMS3714H03 HMS502L06 HQFWVSGBVLEQGA-UHFFFAOYSA-N
    HY-B1007 IDI1_000864 J-008557
    J-008559 KBio1_000864 KBio2_002042
    KBio2_004610 KBio2_007178 KBio3_002827
    KBioGR_000857 KBioSS_002042 LS-122041
    MCULE-4554935124 MLS000028619 NCGC00016411-01
    NCGC00016411-02 NCGC00016411-03 NCGC00016411-04
    NCGC00016411-05 NCGC00016411-06 NCGC00016411-07
    NCGC00016411-10 NCGC00023714-03 NCGC00023714-04
    NCGC00023714-05 NINDS_000864 NSC-758632
    NSC758632 Opera_ID_1473 Pharmakon1600-01503914
    Prestwick0_000831 Prestwick1_000831 Prestwick2_000831
    Prestwick3_000831 Prestwick_984 Q5002339
    SBI-0051856.P002 SCHEMBL26156 SMR000058686
    SPBio_001586 SPBio_002702 SPECTRUM1503914
    SR-01000003139 SR-01000003139-2 SR-01000003139-3
    ST51014906 SW197068-3 Spectrum2_001593
    Spectrum3_001943 Spectrum4_000219 Spectrum5_001565
    Spectrum_001562 Tox21_110428 Tox21_110428_1
    UNII-Z84S23CGJJ Z84S23CGJJ ZINC1596184
    butacaine p-Aminobenzoyldibutylaminopropanol

    DrugBank Name Butacaine
    DrugBank DB11502
    CAS Number 149-15-5, 149-16-6
    PubChem Compound 2480
    ChEBI 94820
    ChemSpider 2386
    BindingDB 50225491.0
    Wikipedia Butacaine
    DPD 6632

    1. Chan et al. (2005)