D0041 | Disopyramide
C
C01BA03 Disopyramide
[C01BA] Antiarrhythmics, class Ia
[C01B] ANTIARRHYTHMICS, CLASS I AND III
[C01] CARDIAC THERAPY
[C] Cardiovascular system
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
 |
Warning |
Aggregated GHS information provided by 41 companies from 2 notifications to the ECHA C&L Inventory. H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P264, P270, P301+P312, P330, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
 |
Warning |
Aggregated GHS information provided by 42 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] H361 (90.48%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P201, P202, P264, P270, P281, P301+P312, P308+P313, P330, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| Organism | Test type | Route | Dose (normalized dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intravenous | 46400ug/kg (46.4mg/kg) | Jitchuken Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Research Reports. Vol. 7, Pg. 257, 1981. | |
| .alpha.-(2-(Diisopropylamino)ethyl)-.alpha.-phenyl-2-pyridineacetamide | .gamma.-Diisopropylamino-.alpha.-phenyl-.alpha.-(2-pyridyl)butyramide | 2-Pyridineacetamide, .alpha.-[2-(diisopropylamino)ethyl]-.alpha.-phenyl- |
| 2-Pyridineacetamide, .alpha.-[2-[bis(1-methylethyl)amino]ethyl]-.alpha.-phenyl- | 2-Pyridineacetamide, alpha-(2-(bis(1-methylethyl)amino)ethyl)-alpha-phenyl- | 2-Pyridineacetamide, alpha-(2-(diisopropylamino)ethyl)-alpha-phenyl- |
| 20509-EP2272972A1 | 20509-EP2272973A1 | 20509-EP2277872A1 |
| 20509-EP2314585A1 | 3737-09-5 | 4-(Diisopropylamino)-2-phenyl-2-(2-pyridinyl)butanamide |
| 4-(Diisopropylamino)-2-phenyl-2-(2-pyridinyl)butanamide # | 4-(Diisopropylamino)-2-phenyl-2-(2-pyridyl)butyramide | 4-(diisopropylamino)-2-phenyl-2-(pyridin-2-yl)butanamide |
| 4-(diisopropylamino)-2-phenyl-2-pyridin-2-ylbutanamide | 4-Diisopropylamino-2-phenyl-2-(2-pyridyl)-butyramide | 4-[bis(methylethyl)amino]-2-phenyl-2-(2-pyridyl)butanamide |
| 4-[bis(propan-2-yl)amino]-2-phenyl-2-(pyridin-2-yl)butanamide | 4-[bis(propan-2-yl)amino]-2-phenyl-2-(pyridin-2-yl)butanimidic acid | 4-[di(propan-2-yl)amino]-2-phenyl-2-pyridin-2-ylbutanamide |
| AB00053462 | AB00053462_16 | AB00053462_17 |
| AC-16018 | AK688967 | AKOS015894712 |
| BDBM50028893 | BPBio1_000124 | BRD-A29734509-001-03-8 |
| BRD-A29734509-011-02-9 | BRD-A29734509-011-06-0 | BSPBio_000112 |
| BSPBio_001928 | C-44340 | C06965 |
| CAS-3737-09-5 | CCG-204495 | CHEBI:4657 |
| CHEMBL517 | CTK1H1096 | D 7644 |
| D00303 | D2793 | DB00280 |
| DSSTox_CID_25536 | DSSTox_GSID_45536 | DSSTox_RID_80938 |
| DTXSID1045536 | Dicorantil | Disopiramida |
| Disopiramida [INN-Spanish] | Disopyramide (JP17/USAN/INN) | Disopyramide 1.0 mg/ml in Methanol |
| Disopyramide Free Base | Disopyramide [USAN:BAN:INN:JAN] | Disopyramide [USAN:INN:BAN:JAN] |
| Disopyramide, European Pharmacopoeia (EP) Reference Standard | Disopyramidum | Disopyramidum [INN-Latin] |
| DivK1c_000489 | EINECS 223-110-2 | EU-0100402 |
| FT-0667714 | GTPL7167 | H 3292 |
| HMS1568F14 | HMS2095F14 | HMS2234G08 |
| HMS3261A06 | HMS3369O21 | HMS3712F14 |
| IDI1_000489 | Isorythm | KBio1_000489 |
| KBio2_001488 | KBio2_004056 | KBio2_006624 |
| KBio3_001148 | KBioGR_001127 | KBioSS_001488 |
| LP00402 | LS-185086 | Lispine |
| Lispine|||Ritmilen | Lopac0_000402 | Lopac0_000411 |
| MCULE-8866988334 | MFCD00029934 | MFCD00057366 |
| MLS002222242 | NCGC00015358-04 | NCGC00015358-05 |
| NCGC00015358-06 | NCGC00015358-08 | NCGC00015358-09 |
| NCGC00015358-10 | NCGC00015358-11 | NCGC00015358-12 |
| NCGC00015358-13 | NCGC00015358-14 | NCGC00015358-15 |
| NCGC00015358-18 | NCGC00015358-19 | NCGC00016985-01 |
| NCGC00093829-01 | NCGC00093829-02 | NCGC00093829-03 |
| NCGC00261087-01 | NINDS_000489 | Norpace (Salt/Mix) |
| Prestwick0_000266 | Prestwick1_000266 | Prestwick2_000266 |
| Prestwick3_000266 | Prestwick_681 | Q425120 |
| Ritmodan | Rythmodan | Rythmodan P (TN) |
| SBI-0050388.P005 | SC 13957 (Salt/Mix) | SC 7031 |
| SC-7031 | SCHEMBL16153 | SMR001307254 |
| SPBio_001245 | SPBio_002331 | SR-01000003039 |
| SR-01000003039-10 | SR-01000003039-3 | ST50411970 |
| Searle 703 | Spectrum2_001033 | Spectrum3_000404 |
| Spectrum4_000524 | Spectrum5_000943 | Spectrum_001008 |
| Tox21_110727 | Tox21_110727_1 | Tox21_500402 |
| UVTNFZQICZKOEM-UHFFFAOYSA-N | Y5028 | Z2786051711 |
| alpha-(2-(Diisopropylamino)ethyl)-alpha-phenyl-2-pyridineacetamide | alpha-Diisopropylaminoethyl-alpha-phenylpyridine-2-acetamide | disopyramide |
| gamma-Diisopropylamino-alpha-phenyl-alpha-(2-pyridyl)butyramide | racemic 2-phenyl-2-(2-pyridyl)-4-[N,N-bis(1-methylethyl)amino]butanamide |
| DrugBank Name | Disopyramide |
| DrugBank | DB00280 |
| CAS Number | 1216989-88-6, 1309283-08-6, 22059-60-5, 3737-09-5, 38236-46-3, 54687-36-4, 856243-80-6 |
| PubChem Compound | 3114 |
| KEGG Compound ID | C06965 |
| KEGG Drug | D00303 |
| PubChem.Substance | 46508226 |
| ChEBI | 4657 |
| PharmGKB | PA449373 |
| ChemSpider | 3002 |
| BindingDB | 50028893.0 |
| TTD | DAP000504 |
| Wikipedia | Disopyramide |
| DPD | 2191 |