Drug

D0101 | Pramocaine

Molecular Formula C17H27NO3
Molecular Weight 293.4
Structure
State solid
Absorption There is minimal absorption after topical administration and it is not given orally.

D

C

D04AB07 Pramocaine


[D04AB] Anesthetics for topical use


[D04A] ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.


[D04] ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.


[D] Dermatological drugs


C05AD07 Pramocaine


[C05AD] Local anesthetics


[C05A] AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE


[C05] VASOPROTECTIVES


[C] Cardiovascular system


Organism Test type Route Dose (normalized dose) Effect Source
mouse LD50 subcutaneous 900mg/kg (900mg/kg) Anesthesia and Analgesia Vol. 38, Pg. 265, 1959.
mouse LD50 intraperitoneal 300mg/kg (300mg/kg) Anesthesia and Analgesia Vol. 38, Pg. 265, 1959.
mouse LD50 intravenous 79mg/kg (79mg/kg) European Journal of Medicinal Chemistry--Chimie Therapeutique. Vol. 10, Pg. 291, 1975.


  • .gamma.-Morpholinopropyl 4-n-butoxyphenyl ether 068X84E056 140-65-8
    4-(3-(4-butoxyphenoxy)propyl)morpholine 4-(3-(p-Butoxyphenoxy)propyl)morpholine 4-27-00-00127 (Beilstein Handbook Reference)
    4-[3-(4-Butoxyphenoxy)propyl]morpholine 4-[3-(4-Butoxyphenoxy)propyl]morpholine # AB00053605
    AB00053605_13 AB00053605_14 BDBM50225493
    BPBio1_001025 BRD-K46523383-003-04-7 BRN 0239059
    BSPBio_000931 C07892 CAS-637-58-1
    CHEBI:8357 CHEMBL1198 CTK6E3413
    D08407 DB09345 DQKXQSGTHWVTAD-UHFFFAOYSA-N
    DTXSID8040692 DivK1c_000882 EINECS 205-425-7
    IDI1_000882 KBio1_000882 KBio2_001860
    KBio2_004428 KBio2_006996 KBio3_001930
    KBioGR_001547 KBioSS_001860 LS-92486
    MCULE-5337294231 Morpholine, 4-(3-(p-butoxyphenoxy)propyl)- Morpholine, 4-[3-(4-butoxyphenoxy)propyl]-
    NCGC00016529-01 NCGC00016529-02 NCGC00016529-03
    NCGC00016529-04 NINDS_000882 PX9
    Pramocaina Pramocaina [INN-Spanish] Pramocaine
    Pramocaine (INN) Pramocaine [INN:BAN] Pramocainum [INN-Latin]
    Prestwick0_000716 Prestwick1_000716 Prestwick2_000716
    Prestwick3_000716 Proxazocain Q1240076
    SBI-0051653.P002 SCHEMBL26020 SPBio_000099
    SPBio_002852 Spectrum2_000030 Spectrum3_000925
    Spectrum4_001024 Spectrum5_001511 Spectrum_001380
    Tronopthane Tronothane UNII-068X84E056
    ZINC19594594 gamma-Morpholinopropyl 4-n-butoxyphenyl ether p-Butoxyphenyl .gamma.-morpholinopropyl ether
    p-Butoxyphenyl gamma-morpholinopropyl ether pramocainum pramoxine

    DrugBank Name Pramocaine
    DrugBank DB09345
    CAS Number 140-65-8, 637-58-1
    PubChem Compound 4886
    KEGG Compound ID C07892
    KEGG Drug D08407
    PubChem.Substance 310265219
    ChEBI 8357
    ChemSpider 4717
    BindingDB 50225493.0
    Wikipedia Pramocaine
    HET PX9
    DPD 6343

    1. Chan et al. (2005)