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Drug

D0102 | Prilocaine

Molecular Formula C13H20N2O
Molecular Weight 220.31
Structure
State solid
Route of elimination Prilocaine is metabolized in both the liver and the kidney and excreted via the kidney.
Protein binding 0.98

N

N01BB54 Prilocaine, combinations


[N01BB] Amides


[N01B] ANESTHETICS, LOCAL


[N01] ANESTHETICS


[N] Nervous system

N01BB04 Prilocaine


[N01BB] Amides


[N01B] ANESTHETICS, LOCAL


[N01] ANESTHETICS


[N] Nervous system

Pictogram Signal Statements Precautionary Statement Codes
Warning

Aggregated GHS information provided by 68 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.


H302 (98.53%): Harmful if swallowed [Warning Acute toxicity, oral]


H315 (92.65%): Causes skin irritation [Warning Skin corrosion/irritation]


H319 (92.65%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]


H412 (98.53%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]


Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.


 P264, P270, P273, P280, P301+P312, P302+P352, P305+P351+P338, P321, P330, P332+P313, P337+P313, P362, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)

  • Agitation

  • Cardiac arrest

  • Cardiovascular insufficiency

  • Convulsion

  • Foetal acidosis

  • Ischaemia

  • Methaemoglobinaemia

    • (.+/-.)-Prilocaine (RS)-N-(2-Methylphenyl)-2-(propylamino)propanamide .alpha.-n-Propyl-amino-2-methylpropionanilide
    046O35D44R 2-(Propylamino)-N-(o-tolyl)propanamide 2-(Propylamino)-o-propionotoluidide
    2-(propylamino)-N-o-tolylpropanamide 2-Methyl-.alpha.-propylaminopropionanilide 2-Methyl-alpha-propylaminopropionanilide
    4CH-023339 721-50-6 721-50-6,1786-81-8(HCl)
    86P818 A837435 AB00053665
    AB00053665-12 AB00053665_13 AB00053665_14
    AB2000166 ABP000640 AC-2100
    ACT04759 AKOS015889404 ARONIS27056
    AS-14851 Astra 1512 Astra 1515
    BDBM50225477 BPBio1_000173 BRD-A53952395-003-05-3
    BRD-A53952395-003-15-2 BRN 2108498 BSPBio_000157
    BSPBio_002604 C07531 CCG-205085
    CHEBI:8404 CHEMBL1194 CS-1929
    CTK2H7603 Citanest D00553
    DB-055611 DB00750 DTXSID7031955
    DivK1c_000846 EBD798 EINECS 211-957-0
    FT-0603506 FT-0660568 GTPL7276
    HMS3604H09 HMS3651M13 HSDB 3386
    HY-B0137 IDI1_000846 KBio1_000846
    KBio2_002129 KBio2_004697 KBio2_007265
    KBio3_001824 KBioGR_001883 KBioSS_002129
    KS-00000XMI KS-000048JX L 67
    LS-2304 Lopac0_001005 MCULE-7176365958
    MVFGUOIZUNYYSO-UHFFFAOYSA-N N-(2-Methylphenyl)-2-(propylamino)propanamide N-(2-Methylphenyl)-2-(propylamino)propanamide #
    N-(2-methylphenyl)-2-(propylamino)propanimidic acid N-(2-methylphenyl)-2-propylamino-propanamide N-(2-methylphenyl)-N(2)-propylalaninamide
    N-(2-methylphenyl)-N2-propylalaninamide N-(2-methylphenyl)-N~2~-propylalaninamide N1-(2-methylphenyl)-N2-propylalaninamide
    NCGC00015860-02 NCGC00015860-03 NCGC00162312-01
    NE41881 NINDS_000846 NSC 40027
    NSC-40027 NSC40027 Prestwick0_000199
    Prestwick1_000199 Prestwick2_000199 Prestwick3_000199
    Prilocain Prilocaina Prilocaina [INN-Spanish]
    Prilocaine (USP/INN) Prilocaine [USAN:USP:INN:BAN] Prilocaine [USAN]
    Prilocaine, 98% Prilocaine/ Prilocainum
    Prilocainum [INN-Latin] Prilotekal Propanamide, N-(2-methylphenyl)-2-(propylamino)-
    Propanamide, N-(2-methylphenyl)-2-(propylamino)- (9CI) Propitocaine Propitocaine (JAN)
    Propranamide, N-(2-methylphenyl)-2-(propylamino)- Q-100809 Q413598
    SBI-0050978.P003 SC-26688 SCHEMBL25467
    SPBio_001398 SPBio_002078 STL257086
    SW196783-3 Spectrum2_001549 Spectrum3_001052
    Spectrum4_001192 Spectrum5_001175 Spectrum_001649
    UNII-046O35D44R alpha-n-Propylamino-2-methylpropionanilide o-Methyl-.alpha.-propylaminopropionanilide
    o-Methyl-2-propylaminopropionanilide o-Methyl-alpha-propylaminopropionanilide o-Propionotoluidide, 2-(propylamino)-
    o-Propionotoluidide, 2-propylamino- o-Propionotuluidide, 2-propylamino- prilocaine
    prilocaine base s1619

    DrugBank Name Prilocaine
    DrugBank DB00750
    CAS Number 14289-31-7, 14289-32-8, 1786-81-8, 721-50-6
    PubChem Compound 4906
    KEGG Compound ID C07531
    KEGG Drug D00553
    PubChem.Substance 46505066
    ChEBI 8404
    PharmGKB PA451101
    ChemSpider 4737
    BindingDB 50225477.0
    TTD DAP000511
    Wikipedia Prilocaine
    DPD 5776|9797

    1. Chan et al. (2005)