D0177 | Epichlorohydrin
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
     |
Danger |
H226: Flammable liquid and vapor [Warning Flammable liquids] H301: Toxic if swallowed [Danger Acute toxicity, oral] H311: Toxic in contact with skin [Danger Acute toxicity, dermal] H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation] H317: May cause an allergic skin reaction [Warning Sensitization, Skin] H331: Toxic if inhaled [Danger Acute toxicity, inhalation] H350: May cause cancer [Danger Carcinogenicity] |
P201, P202, P210, P233, P240, P241, P242, P243, P260, P261, P264, P270, P271, P272, P280, P281, P301+P310, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P308+P313, P310, P311, P312, P321, P322, P330, P333+P313, P361, P363, P370+P378, P403+P233, P403+P235, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
|
|
Danger |
Aggregated GHS information provided by 1642 companies from 26 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. Reported as not meeting GHS hazard criteria by 1 of 1642 companies. For more detailed information, please visit ECHA C&L website Of the 25 notification(s) provided by 1641 of 1642 companies with hazard statement code(s): H226 (100%): Flammable liquid and vapor [Warning Flammable liquids] H301+H331 (26.87%): Toxic if swallowed or if inhaled [Danger Acute toxicity, oral acute toxicity, inhalation] H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral] H311 (100%): Toxic in contact with skin [Danger Acute toxicity, dermal] H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation] H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin] H318 (46.8%): Causes serious eye damage [Danger Serious eye damage/eye irritation] H330 (33.15%): Fatal if inhaled [Danger Acute toxicity, inhalation] H331 (66.85%): Toxic if inhaled [Danger Acute toxicity, inhalation] H350 (99.94%): May cause cancer [Danger Carcinogenicity] H361 (19.01%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity] H412 (40.1%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P201, P202, P210, P233, P240, P241, P242, P243, P260, P261, P264, P270, P271, P272, P273, P280, P281, P284, P301+P310, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P308+P313, P310, P311, P312, P320, P321, P322, P330, P333+P313, P361, P363, P370+P378, P403+P233, P403+P235, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
|
|
Danger |
H226: Flammable liquid and vapor [Warning Flammable liquids] H301: Toxic if swallowed [Danger Acute toxicity, oral] H311: Toxic in contact with skin [Danger Acute toxicity, dermal] H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation] H317: May cause an allergic skin reaction [Warning Sensitization, Skin] H331: Toxic if inhaled [Danger Acute toxicity, inhalation] H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure Respiratory tract irritation] H340: May cause genetic defects [Danger Germ cell mutagenicity] H350: May cause cancer [Danger Carcinogenicity] H361: Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity] |
P201, P202, P210, P233, P240, P241, P242, P243, P260, P261, P264, P270, P271, P272, P280, P281, P301+P310, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P308+P313, P310, P311, P312, P321, P322, P330, P333+P313, P361, P363, P370+P378, P403+P233, P403+P235, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
|
|
Danger |
H226: Flammable liquid and vapor [Warning Flammable liquids] H301: Toxic if swallowed [Danger Acute toxicity, oral] H311: Toxic in contact with skin [Danger Acute toxicity, dermal] H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation] H317: May cause an allergic skin reaction [Warning Sensitization, Skin] H318: Causes serious eye damage [Danger Serious eye damage/eye irritation] H330: Fatal if inhaled [Danger Acute toxicity, inhalation] H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity] H350: May cause cancer [Danger Carcinogenicity] H361: Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity] H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure] H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure] |
P201, P202, P210, P233, P240, P241, P242, P243, P260, P261, P264, P270, P271, P272, P280, P281, P284, P301+P310, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P307+P311, P308+P313, P310, P312, P314, P320, P321, P322, P330, P333+P313, P361, P363, P370+P378, P403+P233, P403+P235, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
|
H402: Harmful to aquatic life [Hazardous to the aquatic environment, acute hazard] |
P273, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) | ||
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|
Danger |
H226: Flammable liquid and vapor [Warning Flammable liquids] H301: Toxic if swallowed [Danger Acute toxicity, oral] H311: Toxic in contact with skin [Danger Acute toxicity, dermal] H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation] H317: May cause an allergic skin reaction [Warning Sensitization, Skin] H318: Causes serious eye damage [Danger Serious eye damage/eye irritation] H330: Fatal if inhaled [Danger Acute toxicity, inhalation] H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory] H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity] H350: May cause cancer [Danger Carcinogenicity] H361: Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity] H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure] H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure] |
P201, P202, P210, P233, P240, P241, P242, P243, P260, P261, P264, P270, P271, P272, P280, P281, P284, P285, P301+P310, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P304+P341, P305+P351+P338, P307+P311, P308+P313, P310, P312, P314, P320, P321, P322, P330, P333+P313, P342+P311, P361, P363, P370+P378, P403+P233, P403+P235, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| Organism | Test type | Route | Dose (normalized dose) | Effect | Source |
|---|---|---|---|---|---|
| rat | LD50 | subcutaneous | 150mg/kg (150mg/kg) | kidney, ureter, and bladder: urine volume increased | Archives des Maladies Professionnelles de Medecine du Travail et de Securite Sociale. Vol. 28, Pg. 505, 1967. |
| human | TCLo | inhalation | 20ppm (20ppm) | "Practical Toxicology of Plastics," Lefaux, R., Cleveland, OH, Chemical Rubber Co., 1968Vol. -, Pg. 108, 1968. | |
| rat | LDLo | skin | 1gm/kg (1000mg/kg) | University of California, Berkeley, Publications in Pharmacology. Vol. 2, Pg. 69, 1941. | |
| mouse | LD50 | skin | 250mg/kg (250mg/kg) | "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 64, 1982. | |
| human | TCLo | inhalation | 40ppm/2H (40ppm) | lungs, thorax, or respiration: other changes | "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 240, 1969. |
| guinea pig | LD50 | oral | 280mg/kg (280mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 33(1), Pg. 46, 1968. | |
| guinea pig | LD50 | intraperitoneal | 118mg/kg (118mg/kg) | Journal of Pharmaceutical Sciences. Vol. 61, Pg. 1712, 1972. | |
| mouse | LD50 | intraperitoneal | 170mg/kg (170mg/kg) | Journal of Pharmaceutical Sciences. Vol. 61, Pg. 1712, 1972. | |
| rabbit | LD50 | intraperitoneal | 160mg/kg (160mg/kg) | Journal of Pharmaceutical Sciences. Vol. 61, Pg. 1712, 1972. | |
| rabbit | LD50 | oral | 345mg/kg (345mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 33(1), Pg. 46, 1968. | |
| rabbit | LD50 | skin | 515mg/kg (515mg/kg) | Personal Communication from M.A. Wolf, Dow Chemical Co., Midland, MI 48640, Jan. 18, 1977Vol. 18JAN1977, | |
| mouse | LD50 | oral | 195mg/kg (195mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 33(1), Pg. 46, 1968. | |
| rat | LC50 | inhalation | 250ppm/8H (250ppm) | Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 41, 1974. | |
| rat | LD50 | intraperitoneal | 113mg/kg (113mg/kg) | Journal of Pharmaceutical Sciences. Vol. 61, Pg. 1712, 1972. | |
| mouse | LCLo | inhalation | 72gm/m3/9M (72000mg/m3) | Journal of Biomedical Materials Research. Vol. 8, Pg. 11, 1974. | |
| rat | LD50 | oral | 90mg/kg (90mg/kg) | Journal of Industrial Hygiene and Toxicology. Vol. 30, Pg. 63, 1948. | |
| rat | LD50 | intravenous | 154mg/kg (154mg/kg) | Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 41, 1974. | |
| mouse | LDLo | subcutaneous | 250mg/kg (250mg/kg) | Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 2, Pg. 28, 1961. | |
| (+) epichlorohydrin | (+/-)-1-Chloro-2,3-epoxypropane | (+/-)-2-(Chloromethyl)oxirane |
| (+/-)-Epichlorohydrin | (+/-)-Epichlorohydrin, analytical standard | (+/-)-Epichlorohydrin, puriss., >=99.5% (GC) |
| (+/-)-Epichlorohydrin, purum, >=99% (GC) | (-) epichlorohydrin | (CHLOROMETHYL)OXIRANE |
| (Chloromethyl)ethylene oxide | (DL)-.alpha.-Epichlorohydrin | (DL)-alpha-Epichlorohydrin |
| (RS)-(chloromethyl)oxirane | (RS)-3-chloro-1,2-epoxypropane | (chloromethyl) Ethylene oxide |
| (chloromethyl)-Oxirane | (rac)-epichlorohydrin | (rs)-epichlorohydrin |
| .alpha.-Epichlorohydrin | .gamma.-Chloropropylene oxide | 1,2-Epoxy-3-chloropropane |
| 1-Chloor-2,3-epoxy-propaan | 1-Chloor-2,3-epoxy-propaan [Dutch] | 1-Chlor-2,3-epoxy-propan |
| 1-Chlor-2,3-epoxy-propan [German] | 1-Chloro-2,3-epoxy propone | 1-Chloro-2,3-epoxypropane |
| 1-Cloro-2,3-epossipropano | 1-Cloro-2,3-epossipropano [Italian] | 1-chloro-2,3-epoxy-propane |
| 106-89-8 | 13403-37-7 | 2,3-Epoxypropyl chloride |
| 2-(Chloromethyl)oxirane | 2-(chloromethyl) Oxirane | 2-(chloromethyl)-oxirane |
| 2-Chloromethyl-oxirane | 2-chloromethyloxirane | 204282-EP2277867A2 |
| 204282-EP2280003A2 | 23287-EP2270113A1 | 23287-EP2270114A1 |
| 23287-EP2272935A1 | 23287-EP2275417A2 | 23287-EP2277867A2 |
| 23287-EP2280003A2 | 23287-EP2280008A2 | 23287-EP2280012A2 |
| 23287-EP2284146A2 | 23287-EP2284147A2 | 23287-EP2284162A2 |
| 23287-EP2284163A2 | 23287-EP2285791A1 | 23287-EP2286811A1 |
| 23287-EP2292597A1 | 23287-EP2295438A1 | 23287-EP2298776A1 |
| 23287-EP2301941A1 | 23287-EP2305666A1 | 23287-EP2308862A1 |
| 23287-EP2308865A1 | 23287-EP2314584A1 | 3-Chloro-1,2-epoxypropane |
| 3-Chloro-1,2-propylene oxide | 3-Chloro-propylene oxide | 3-Chloropro pylene Oxide |
| 3-Chloropropene-1,2-oxide | 3-Chloropropyl epoxide | 3-Chloropropylene oxide |
| 3-chloro-1,2-epoxypropene | 5-17-01-00020 (Beilstein Handbook Reference) | 56227-39-5 |
| 5717-EP2269977A2 | 5717-EP2270011A1 | 5717-EP2272817A1 |
| 5717-EP2272839A1 | 5717-EP2272840A1 | 5717-EP2272841A1 |
| 5717-EP2275418A1 | 5717-EP2277874A1 | 5717-EP2277878A1 |
| 5717-EP2280001A1 | 5717-EP2280009A1 | 5717-EP2280010A2 |
| 5717-EP2284159A1 | 5717-EP2284169A1 | 5717-EP2287161A1 |
| 5717-EP2287162A1 | 5717-EP2292227A2 | 5717-EP2292592A1 |
| 5717-EP2292596A2 | 5717-EP2292628A2 | 5717-EP2295407A1 |
| 5717-EP2295426A1 | 5717-EP2295427A1 | 5717-EP2295434A2 |
| 5717-EP2295437A1 | 5717-EP2298312A1 | 5717-EP2298734A2 |
| 5717-EP2298736A1 | 5717-EP2298750A1 | 5717-EP2298774A1 |
| 5717-EP2298775A1 | 5717-EP2301921A1 | 5717-EP2301924A1 |
| 5717-EP2301926A1 | 5717-EP2301929A1 | 5717-EP2301934A1 |
| 5717-EP2301935A1 | 5717-EP2301936A1 | 5717-EP2301937A1 |
| 5717-EP2301939A1 | 5717-EP2305219A1 | 5717-EP2305649A1 |
| 5717-EP2305658A1 | 5717-EP2305674A1 | 5717-EP2305682A1 |
| 5717-EP2308828A2 | 5717-EP2308857A1 | 5717-EP2308858A1 |
| 5717-EP2308861A1 | 5717-EP2308873A1 | 5717-EP2308875A1 |
| 5717-EP2308877A1 | 5717-EP2308879A1 | 5717-EP2311808A1 |
| 5717-EP2311816A1 | 5717-EP2311817A1 | 5717-EP2311822A1 |
| 5717-EP2311829A1 | 5717-EP2311831A1 | 5717-EP2311846A1 |
| 5717-EP2314558A1 | 5717-EP2314583A1 | 5717-EP2314584A1 |
| 5717-EP2314585A1 | 5717-EP2316824A1 | 5717-EP2316836A1 |
| 5717-EP2371810A1 | 5717-EP2371831A1 | 5717-EP2372804A1 |
| 5717-EP2374454A1 | 5717-EP2378585A1 | 61TTR6T3SE |
| 6660AH | 9009-12-5 | AI3-03545 |
| AKOS000118974 | AKOS016039400 | Allyl chloride oxide |
| Alyl chloride oxide | BBL012223 | BP-31004 |
| BRLQWZUYTZBJKN-UHFFFAOYSA-N | BRN 0079785 | BRN 1420785 |
| C14449 | C3H5ClO | CAS-106-89-8 |
| CCRIS 277 | CCRIS 6387 | CHEBI:37144 |
| CHEMBL1421613 | CTK5A4812 | Cardolite NC-513 |
| Caswell No. 424 | Chloro-1,2-epoxypropane | Chloro-1,2-propylene oxide |
| Chloro-2,3-epoxypropane | Chloromethyloxirane | Chloropropene-1,2-oxide |
| Chloropropyl epoxide | Chloropropylene | Chloropropylene oxide |
| DB-018066 | DL-a-Epichlorohydrin | DSSTox_CID_566 |
| DSSTox_GSID_20566 | DSSTox_RID_75662 | DTXSID1020566 |
| E0012 | EC 203-439-8 | ECH |
| EINECS 203-439-8 | EPA Pesticide Chemical Code 097201 | EPI |
| EPICHLOROHYDRIN | Epichloorhydrine | Epichloorhydrine [Dutch] |
| Epichlorhydrin | Epichlorhydrin 100 microg/mL in Cyclohexane | Epichlorhydrin 1000 microg/mL in Methanol |
| Epichlorhydrine | Epichlorhydrine [French] | Epichloro hydrine |
| Epichlorohydrin Reagent Grade | Epichlorohydrin [UN2023] [Poison] | Epichlorohydrin [UN2023] [Poison] |
| Epichlorohydrin, 99% | Epichlorohydrin, 99%, AcroSeal(R) | Epichlorohydrin, >=99% |
| Epichlorohydryna | Epichlorohydryna [Polish] | Epichlorophydrin |
| Epicloridrina | Epicloridrina [Italian] | Epoxy-3-chlor opropane |
| Epoxy-3-chloropropane | Epoxypropyl chloride | F0001-0128 |
| FT-0625672 | Glycerol epichlorhydrin | Glycerol epichlorohydrin |
| Glycidyl chloride | HSDB 39 | KS-00000V0U |
| LS-101030 | LS-409 | MCULE-9759519789 |
| MFCD00005132 | NCGC00091792-01 | NCGC00091792-02 |
| NCGC00091792-03 | NCGC00257830-01 | NCI-C07001 |
| NSC 6747 | NSC-6747 | NSC6747 |
| Oxirane, (chloromethyl)- | Oxirane, (chloromethyl)-, (R)- | Oxirane, 2-(chloromethyl) |
| Oxirane,(chloromethyl)- | Polidexide | Polidexidi sulfas |
| Polidexidi sulfas [INN-Latin] | Propane, 1-chloro-2,3-epoxy- | Q-201062 |
| Q423083 | RCRA waste no. U041 | Rcra waste number U041 |
| SC-47193 | SKEKhG | STL163564 |
| Starch, 2-(diethylamino)ethyl 2-((2-(diethylamino)ethyl)diethylammonio)ethyl ether, chloride, hydrochloride, polymer with (chloromethyl)oxirane | Sulfate de polidexide | Sulfate de polidexide [INN-French] |
| Sulfato de polidexido | Sulfato de polidexido [INN-Spanish] | TRA0067700 |
| Tox21_111167 | Tox21_200276 | UN 2023 |
| UN2023 | UNII-61TTR6T3SE | WLN: T3OTJ B1G |
| Z955123632 | a-Epichlorohydrin | alpha-Epichlorohydrin |
| beta-epoxypropylchloride | bmse000722 | chloromethyl) Oxirane |
| epi-Chlorohydrin | epi-chlorohydrine | epichiorohydrin |
| epichlorohydrine | gamma-Chloropropylene oxide | oxirane, 2-(chloromethyl)- |
| racemic epichlorohydrin | racemic epichlorohydrine |
| CAS Number | 106-89-8, 108119-59-1, 13403-37-7, 152751-57-0, 24969-10-6, 30515-28-7, 3302-10-1, 51594-55-9, 52757-95-6, 55295-70-0, 56227-39-5, 67843-74-7, 9009-12-5 |
| PubChem Compound | 7835 |
| KEGG Compound ID | C14449 |
| ChEBI | 37144 |
| ChemSpider | 13837112 |
| Wikipedia | Epichlorohydrin |