D0243 | 1-chloro-2,4-dinitrobenzene (DNCB)
| Target | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| Thioredoxin reductase 2, mitochondrial | human or bovine | inhibit | 319 | |||||
| Thioredoxin reductase 2, mitochondrial | conjugated CDNB to the triphenylphosphonium (TPP) cation to make mitochondria-targeting CDNB (MitoCDNB) | inhibit | 320 | |||||
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
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Danger |
Aggregated GHS information provided by 108 companies from 18 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. Reported as not meeting GHS hazard criteria by 1 of 108 companies. For more detailed information, please visit ECHA C&L website Of the 17 notification(s) provided by 107 of 108 companies with hazard statement code(s): H301+H331 (35.51%): Toxic if swallowed or if inhaled [Danger Acute toxicity, oral acute toxicity, inhalation] H301 (51.4%): Toxic if swallowed [Danger Acute toxicity, oral] H302 (46.73%): Harmful if swallowed [Warning Acute toxicity, oral] H310 (84.11%): Fatal in contact with skin [Danger Acute toxicity, dermal] H311 (14.95%): Toxic in contact with skin [Danger Acute toxicity, dermal] H315 (86.92%): Causes skin irritation [Warning Skin corrosion/irritation] H317 (82.24%): May cause an allergic skin reaction [Warning Sensitization, Skin] H318 (86.92%): Causes serious eye damage [Danger Serious eye damage/eye irritation] H331 (52.34%): Toxic if inhaled [Danger Acute toxicity, inhalation] H373 (52.34%): Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure] H400 (88.79%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410 (99.07%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P260, P261, P262, P264, P270, P271, P272, P273, P280, P301+P310, P301+P312, P302+P350, P302+P352, P304+P340, P305+P351+P338, P310, P311, P312, P314, P321, P322, P330, P332+P313, P333+P313, P361, P362, P363, P391, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
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Danger |
H302: Harmful if swallowed [Warning Acute toxicity, oral] H310: Fatal in contact with skin [Danger Acute toxicity, dermal] H315: Causes skin irritation [Warning Skin corrosion/irritation] H317: May cause an allergic skin reaction [Warning Sensitization, Skin] H318: Causes serious eye damage [Danger Serious eye damage/eye irritation] H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure Respiratory tract irritation] H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity] H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure] H373: Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure] |
P201, P202, P260, P261, P262, P264, P270, P271, P272, P280, P281, P301+P312, P302+P350, P302+P352, P304+P340, P305+P351+P338, P307+P311, P308+P313, P310, P312, P314, P321, P322, P330, P332+P313, P333+P313, P361, P362, P363, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
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|
Danger |
H302: Harmful if swallowed [Warning Acute toxicity, oral] H310: Fatal in contact with skin [Danger Acute toxicity, dermal] H315: Causes skin irritation [Warning Skin corrosion/irritation] H317: May cause an allergic skin reaction [Warning Sensitization, Skin] H318: Causes serious eye damage [Danger Serious eye damage/eye irritation] H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure Respiratory tract irritation] H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity] H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure] H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure] H373: Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure] |
P201, P202, P260, P261, P262, P264, P270, P271, P272, P280, P281, P301+P312, P302+P350, P302+P352, P304+P340, P305+P351+P338, P307+P311, P308+P313, P310, P312, P314, P321, P322, P330, P332+P313, P333+P313, P361, P362, P363, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| 1 - Chloro - 2,4 - dinitrobenzene | 1,3-Dinitro-4-chlorobenzene | 1-Chloor-2,4-dinitrobenzeen |
| 1-Chloor-2,4-dinitrobenzeen [Dutch] | 1-Chlor-2,4-dinitrobenzene | 1-Chlor-2,4-dinitrobenzol |
| 1-Chloro-2,4-dinitrobenzeen | 1-Chloro-2,4-dinitrobenzeen [Dutch] | 1-Chloro-2,4-dinitrobenzene 100 microg/mL in Methanol |
| 1-Chloro-2,4-dinitrobenzene, 97% | 1-Chloro-2,4-dinitrobenzene, 99% | 1-Chloro-2,4-dinitrobenzene, >=99% |
| 1-Chloro-2,4-dinitrobenzene, technical grade, 95% | 1-Chloro-2,4-dinitrobenzene, ~95% | 1-Chloro-2,4-dinitrobenzol |
| 1-Chloro-2,4-dinitrobenzol [German] | 1-Cloro-2,4-dinitrobenzene | 1-Cloro-2,4-dinitrobenzene [Italian] |
| 1-chloro-2,4-dinitro benzene | 1-chloro-2,4-dinitro-benzene | 1-chloro-2,4-dinitrobenzene |
| 2,4-Dinitro-1-chlorobenzene | 2,4-Dinitrochlorobenzene | 2,4-Dinitrophenyl chloride |
| 2,4-dinitro chlorobenzene | 2,4-dinitro-chloro-benzene | 2,4-dinitro-chlorobenzene |
| 2,4-dinitrochlorbenzene | 2,4dinitro-1-chlorobenzene | 2-chloro-1,5-dinitrobenzene |
| 3-(3-hydroxy-2-methyl-4-oxo-1-pyridyl)propanoic acid | 4-Chloro-1,3-dinitrobenzene | 6-Chloro-1,3-dinitrobenzene |
| 97-00-7 | ACMC-209s83 | AI3-01053 |
| AKOS000118946 | AM20050502 | ANW-40849 |
| ARONIS27043 | AZ0001-0018 | B-1264 |
| BBL009322 | BCP27853 | BIDD:ER0694 |
| Benzene, 1-chloro-2,4-dinitro- | C14397 | C6H3ClN2O4 |
| CAS-97-00-7 | CCRIS 1799 | CDNB |
| CHEBI:34718 | CHEMBL292687 | CTK3I6861 |
| Caswell No. 389C | ClDNB | DB-057658 |
| DB11831 | DNCB | DNPCl |
| DSSTox_CID_278 | DSSTox_GSID_20278 | DSSTox_RID_75481 |
| DTXSID6020278 | Dinitrochlorobenzene | Dinitrochlorobenzene (VAN) |
| Dinitrochlorobenzol | EC 202-551-4 | EINECS 202-551-4 |
| EPA Pesticide Chemical Code 055102 | Epitope ID:110163 | F1908-0126 |
| GE3IBT7BMN | HMS2233O04 | HSDB 5306 |
| InChI=1/C6H3ClN2O4/c7-5-2-1-4(8(10)11)3-6(5)9(12)13/h1-3 | KS-000017P6 | KS-000048JI |
| LS-2020 | MCULE-9671248933 | MFCD00007075 |
| MLS001332459 | MLS001332460 | NCGC00164061-01 |
| NCGC00164061-02 | NCGC00164061-03 | NCGC00256396-01 |
| NCGC00259505-01 | NSC 6292 | NSC-6292 |
| NSC6292 | Q209216 | RTR-032483 |
| SBB060419 | SC-46724 | SCHEMBL39251 |
| SMR000857169 | ST50826821 | STK387094 |
| STR01511 | TR-032483 | Tox21_201956 |
| Tox21_302802 | UNII-GE3IBT7BMN | VYZAHLCBVHPDDF-UHFFFAOYSA-N |
| W-100123 | WLN: WNR BG ENW | ZINC1540301 |
| chloro-2,4-dinitrobenzene |
| DrugBank Name | Dinitrochlorobenzene |
| DrugBank | DB11831 |
| CAS Number | 4920-05-2, 619-16-9, 97-00-7 |
| PubChem Compound | 6 |
| KEGG Compound ID | C14397 |
| ChEBI | 34718 |
| ChemSpider | 13868426 |
| Wikipedia | 2,4-Dinitrochlorobenzene |