Compound
D0245 | 5-Hydroxydecanoate
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| MITOCHONDRIAL FATTY ACID BETA OXIDATION | 100 μm | decrease | 189 | |||||
| MITOCHONDRIAL FATTY ACID BETA OXIDATION | K1/2 values 45-75 microM | heart and liver mitochondria from rat | decrease | 190 | ||||
| TRANSPORT OF POTASSIUM | 500mmol/L | Primary Culture of Neonatal Rat Cardiac Ventricular Myocytes | flow cytometry and quantitative image analysis of cells stained with fluorescent DC indicators. | affect | 188 | |||
| Target | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| mitochondrial KATP chanel (mtKATP) | 500mmol/L | Primary Culture of Neonatal Rat Cardiac Ventricular Myocytes | flow cytometry and quantitative image analysis of cells stained with fluorescent DC indicators. | inhibitor | 188 | |||
| 5-hydroxydecanoate | CCG-204716 | CTK6D6864 |
| NCGC00162206-01 | NCGC00162206-02 | NCGC00162206-03 |