Compound
D0257 | Celastrol
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
 |
Danger |
Aggregated GHS information provided by 39 companies from 1 notifications to the ECHA C&L Inventory. H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P264, P270, P301+P310, P321, P330, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| Organism | Test type | Route | Dose (normalized dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 350mg/kg (350mg/kg) | Farmatsevtichnii Zhurnal Vol. 26(5), Pg. 20, 1971. | |
| (20alpha)-3-hydroxy-2-oxo-D:A-Friedo-24-noroleana-1(10),3,5,7-tetraen-29-oate | (20alpha)-3-hydroxy-2-oxo-D:A-Friedo-24-noroleana-1(10),3,5,7-tetraen-29-oic acid | (2R,4aS,6aR,6aS,14aS,14bR)-10-hydroxy-2,4a,6a,6a,9,14a-hexamethyl-11-oxo-1,3,4,5,6,13,14,14b-octahydropicene-2-carboxylic acid |
| (2R,4aS,6aS,12bR,14aS,14bR)-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydro-10-hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-2-picenecarboxylic acid | (2R,4aS,6aS,12bR,14aS,14bR)-10-hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydropicene-2-carboxylic acid | 1,2,3,4,4a,5,6,6a, 11,12b,13,14,14a,14b-tetradecahydro-10-hydroxy-2,4a,6a,9,12b, 14a-hexamethyl-11-oxo-2-Picenecarboxylic acid |
| 10-Hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydro-picene-2-carboxylic acid | 157C830 | 2-Picenecarboxylic acid,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydro-10-hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo- |
| 3-Hydroxy-24-nor-2-oxo-1(10),3,5,7-friedelatetraen-29-oic Acid | 3-Hydroxy-9.beta.,13.alpha.-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid | 3-hydroxy-9beta,13alpha-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid |
| 34157-83-0 | AC-6031 | AKOS025311497 |
| API0001923 | BCP07973 | BDBM205457 |
| BSPBio_001905 | C29H38O4 | CC0152 |
| CCG-39919 | CHEBI:63959 | CS-0409 |
| Celastrol, >=98% (HPLC), solid | Celastrol, Celastrus scandens | D:A-Friedo-24-noroleana-1(10),3,5,7-tetraen-29-oic acid, 3-hydroxy-2-oxo-, (20alpha)- |
| DTXSID2040993 | DivK1c_000718 | EBD30960 |
| GS-6082 | GTPL10386 | HMS1923A13 |
| HMS3649E12 | HY-13067 | IDI1_000718 |
| KBio1_000718 | KBio2_000815 | KBio2_003383 |
| KBio2_005951 | KBio3_001405 | KBioGR_002436 |
| KBioSS_000815 | KQJSQWZMSAGSHN-JJWQIEBTSA-N | L8GG98663L |
| LS-157465 | MFCD03424073 | MLS002701906 |
| MLS006011086 | N1731 | NCGC00178913-01 |
| NCGC00178913-04 | NCI60_038570 | NINDS_000718 |
| NSC 70931 | NSC-70931 | NSC70931 |
| Q-100413 | Q5057534 | S492 |
| SC-19832 | SCHEMBL14954 | SMR004702874 |
| SPBio_000260 | SPECTRUM201664 | SR-05000002679 |
| SR-05000002679-1 | SR-05000002679-3 | SR-05000002679-4 |
| ST24050307 | Spectrum2_000150 | Spectrum3_000233 |
| Spectrum4_001966 | Spectrum5_000805 | Spectrum_000335 |
| Tripterin | Tripterine | UNII-L8GG98663L |
| W-5302 | ZINC19795938 | celastrol |
| s1290 |