Compound
D0260 | Cromakalim
| Organism | Test type | Route | Dose (normalized dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD | intravenous | > 4mg/kg (4mg/kg) | Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 22(Suppl, | |
| mouse | LD | oral | > 750mg/kg (750mg/kg) | Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 22(Suppl, | |
| rat | LD | intravenous | > 4mg/kg (4mg/kg) | lungs, thorax, or respiration: respiratory stimulation | Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 22(Suppl, |
| rat | LD | oral | > 2500mg/kg (2500mg/kg) | Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 22(Suppl, | |
| (+)-Cromakalim | (+/-)-cromakalim | (3R-trans)-Cromakalim |
| 2H-1-Benzopyran-6-carbonitrile, 3,4-dihydro-3-hydroxy-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)-, (3R-trans)- | 2H-Benzopyran-6-carbonitrile, 3,4-dihydro-3-hydroxy-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)- | 3-Hydroxy-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)-6-chromanecarbonitrile # |
| 3-hydroxy-2,2-dimethyl-4-(2-oxopyrrolidin-1-yl)chroman-6-carbonitrile | 94470-67-4 | 94535-51-0 |
| AKOS030255268 | BDBM86251 | BRD-A76093993-001-01-8 |
| BRL 38226 | BRL-34915 | C11819 |
| CAS_94535-50-9 | CHEBI:3921 | CHEMBL49035 |
| CROMAKALIM (-) | CTK8F1492 | Cromakalim |
| Cromakalim, (3R-trans)-Isomer | DB-057507 | FT-0624100 |
| GTPL2413 | HMS3267D04 | HMS3369L14 |
| KS-0000186M | NSC_93504 | SCHEMBL3312760 |
| TVZCRIROJQEVOT-UHFFFAOYSA-N |
| CAS Number | 94470-67-4, 94535-50-9, 94535-51-0 |
| PubChem Compound | 443423 |
| KEGG Compound ID | C11819 |
| ChemSpider | 64327 |
| Wikipedia | Cromakalim |