D0295 | Pinacidil
C
C02LX01 Pinacidil and diuretics
[C02LX] Other antihypertensives and diuretics
[C02L] ANTIHYPERTENSIVES AND DIURETICS IN COMBINATION
[C02] ANTIHYPERTENSIVES
[C] Cardiovascular system
C02DG01 Pinacidil
[C02DG] Guanidine derivatives
[C02D] ARTERIOLAR SMOOTH MUSCLE, AGENTS ACTING ON
[C02] ANTIHYPERTENSIVES
[C] Cardiovascular system
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| TRANSPORT OF POTASSIUM | affect | 188 | ||||||
| Target | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| mitochondrial KATP chanel (mtKATP) | opener | 188 | ||||||
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
 |
Warning |
Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure Respiratory tract irritation] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| ( inverted question mark)-N-Cyano-N'-4-pyridinyl-N''-(1,2,2-trimethylpropyl)-guanidine | ()-N-Cyano-N''-4-pyridinyl-N''''-(1,2,2-trimethylpropyl)guanidine | (+-)-Pinacidil |
| (+/-)-Pinacidil | (R,S)-Pinacidil | (Z)-2-cyano-1-(3,3-dimethylbutan-2-yl)-3-(pyridin-4-yl)guanidine |
| 1-cyano-2-(3,3-dimethylbutan-2-yl)-3-pyridin-4-ylguanidine | 113563-71-6 | 2-Cyano-3-(4-pyridinyl)-1-(1,2,2-trimethylpropyl)guanidine |
| 2-Cyano-3-(4-pyridyl)-1-(1,2,2-trimethylpropyl)guanidine monohydrate | 2657AH | 3-cyano-2-(3,3-dimethylbutan-2-yl)-1-pyridin-4-ylguanidine |
| 371P648 | 4N-cyanoimino(1,2,2-trimethylpropylamino)methyl-4-pyridinamine(Pinacidil) | 4N-cyanoimino[1,2,2-trimethyl-(1R)-propylamino]methyl-4-pyridinamine |
| 4N-cyanoimino[1,2,2-trimethyl-(1S)-propylamino]methyl-4-pyridinamine | 560P330 | 60560-33-0 |
| AB00052442-04 | AB00052442_05 | AB00052442_06 |
| ACMC-20mijl | AKOS001637331 | AKOS025394868 |
| API0008270 | BCBcMAP01_000050 | BDBM50103517 |
| BDBM50240750 | BDBM86245 | BPBio1_000036 |
| BRD-A43882281-001-06-4 | BRD-A43882281-001-11-4 | BRD-A58207013-001-01-2 |
| BSPBio_000032 | BSPBio_001461 | BSPBio_002360 |
| Bio1_000164 | Bio1_000653 | Bio1_001142 |
| Bio2_000181 | Bio2_000661 | CAS_85371-64-8 |
| CBiol_001878 | CCG-205115 | CCG-222341 |
| CCG-39493 | CHEBI:91706 | CHEMBL1159 |
| CTK5F4813 | DTXSID7048249 | DivK1c_006855 |
| EINECS 262-294-9 | EU-0101037 | FT-0630932 |
| GTPL2412 | Guanidine, 2-cyano-3-(4-pyridyl)-1-(1,2,2-trimethylpropyl)-, monohydrate | Guanidine, N-cyano-N'-4-pyridinyl-N''-(1,2,2-trimethylpropyl)- |
| Guanidine, N-cyano-N'-4-pyridinyl-N''-(1,2,2-trimethylpropyl)-, monohydrate | Guanidine, N-cyano-N'-4-pyridinyl-N''-[(1R)-1,2,2-trimethylpropyl]- | Guanidine,N-cyano-N'-4-pyridinyl-N''-(1,2,2-trimethylpropyl)-, hydrate (1:1) |
| HMS1361J03 | HMS1568B14 | HMS1791J03 |
| HMS1922L10 | HMS1989J03 | HMS2089C19 |
| HMS2094G21 | HMS2095B14 | HMS2234F10 |
| HMS3263O15 | HMS3267P10 | HMS3371H14 |
| HMS3402J03 | HMS3712B14 | IDI1_033931 |
| IVVNZDGDKPTYHK-UHFFFAOYSA-N | KBio1_001799 | KBio2_000181 |
| KBio2_000867 | KBio2_002749 | KBio2_003435 |
| KBio2_005317 | KBio2_006003 | KBio3_000361 |
| KBio3_000362 | KBioGR_000181 | KBioSS_000181 |
| KBioSS_000867 | LP01037 | LS-73486 |
| Lopac0_001037 | MCULE-2402591602 | MLS000069377 |
| MLS002154248 | N''''-cyano-N-pyridin-4-yl-N''-(1,2,2-trimethylpropyl)guanidine | N''''-cyano-N-pyridin-4-yl-N''-(1,2,2-trimethylpropyl)guanidine ((+)-pinacidil) |
| N''''-cyano-N-pyridin-4-yl-N''-(1,2,2-trimethylpropyl)guanidine (Pinacidil) | N''''-cyano-N-pyridin-4-yl-N''-[(1R)-1,2,2-trimethylpropyl]guanidine | N''''-cyano-N-pyridin-4-yl-N''-[(1S)-1,2,2-trimethylpropyl]guanidine |
| N-Cyano-N'-4-pyridinyl-N''-(1,2,2-trimethylpropyl)guanidine | N-Pyridin-4-yl-N''-(1,2,2-trimethyl-propyl)-cyanoguanidine (pinacidil) | N-cyano-N'-(4-pyridyl)-N''-(1,2,2-trimethylpropyl)guanidine |
| NCGC00015787-02 | NCGC00015787-03 | NCGC00015787-04 |
| NCGC00015787-05 | NCGC00015787-06 | NCGC00025188-02 |
| NCGC00025188-03 | NCGC00025188-04 | NCGC00025188-05 |
| NCGC00025188-06 | NCGC00025188-07 | NCGC00025188-08 |
| NCGC00095199-01 | NCGC00095199-02 | NCGC00095199-03 |
| NCGC00095199-04 | NCGC00188958-01 | NCGC00247667-01 |
| NCGC00261722-01 | NSC-759588 | NSC759588 |
| NSC_4826 | Opera_ID_1844 | P 1134 |
| P-154 | Pharmakon1600-02300270 | Pinacidil (anhydrous) |
| Pinacidil [INN] | Pinacidil anhydrous | Pinacidilum |
| Pinacidilum [INN-Latin] | Prestwick0_000246 | Prestwick1_000246 |
| Prestwick2_000246 | Prestwick3_000246 | Prestwick_396 |
| Q821869 | RT-004885 | S 1230 |
| S-1230 | SBI-0051008.P004 | SCHEMBL65787 |
| SCHEMBL9260276 | SMR000058360 | SPBio_001818 |
| SPBio_002251 | SPECTRUM2300270 | SR-01000075340 |
| SR-01000075340-1 | SR-01000075340-3 | SR-05000001757 |
| SR-05000001757-1 | SR-05000001757-2 | SW197742-2 |
| SpecPlus_000759 | Spectrum2_001739 | Spectrum5_001372 |
| Spectrum_000387 | Tox21_501037 | pinacidil |