Compound

D0480 | ezlopitant

Molecular Formula C31H38N2O
Molecular Weight 454.6
Structure

Toxicity Dose Time Species Model Method Action Positive criterion Reference
UNCOUPLING rat isolated liver mitochondria measurements of mitochondrial respiration; RST inhibition assay, RST uncoupling assay; IC 50ratio of glucose/galactose assay increase 53


  • ((2S,3S)-2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yl)-(5-isopropyl-2-methoxy-benzyl)-amine (2S,3S)-2-(Diphenylmethyl)-3-((5-isopropyl-2-methoxybenzyl)amino)quinuclidine (7S,8S)-7-[di(phenyl)methyl]-N-[(2-methoxy-5-propan-2-ylphenyl)methyl]-1-azabicyclo[2.2.2]octan-8-amine
    1-Azabicyclo(2.2.2)octan-3-amine, 2-(diphenylmethyl)-N-((2-methoxy-5-(1-methylethyl)phenyl)methyl)-, (2S-cis)-; 147116-64-1 2beta-(Diphenylmethyl)-3beta-(2-methoxy-5-isopropylbenzylamino)-1beta,4beta-ethanopiperidine
    3L098A8MPY BDBM50262567 CHEMBL515966
    CJ 11974 CJ-11, 974 CJ-11974
    CJ11974 D04122 Ezlopitant
    Ezlopitant (USAN/INN) Ezlopitant [USAN:INN] GTPL5751
    Q1386050 SCHEMBL383011 SCHEMBL9069731
    UNII-3L098A8MPY

    CAS Number 147116-64-1, 17514-60-2
    PubChem Compound 188927
    KEGG Drug D04122