Compound
D0538 | fumarate
| Target | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | competitive inhibitor | 79 | ||||||
| Organism | Test type | Route | Dose (normalized dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | unreported | 5gm/kg (5000mg/kg) | Toksikologicheskii Vestnik. Vol. (2), Pg. 25, 1994. | |
| mouse | LD50 | intraperitoneal | 100mg/kg (100mg/kg) | National Technical Information Service. Vol. AD277-689, | |
| rat | LDLo | intraperitoneal | 587mg/kg (587mg/kg) | Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 35, Pg. 298, 1946. | |
| rat | LD50 | unreported | 6800mg/kg (6800mg/kg) | Toksikologicheskii Vestnik. Vol. (2), Pg. 25, 1994. | |
| rabbit | LDLo | oral | 5gm/kg (5000mg/kg) | Industrial and Engineering Chemistry. Vol. 15, Pg. 628, 1923. | |
| rat | LD50 | oral | 9300mg/kg (9300mg/kg) | Toxicology and Applied Pharmacology. Vol. 42, Pg. 417, 1977. | |
| (2E)-but-2-enedioate | (E)-1,2-Ethylenedicarboxylic acid | (E)-2-Butenedioate |
| (E)-2-butenedioic acid, ion(2-) | (E)-Butenedioic acid | 142-42-7 |
| 2-Butenedioic acid (E)-, ion(2-) | 3861-EP2269977A2 | 3861-EP2269978A2 |
| 3861-EP2269985A2 | 3861-EP2269991A2 | 3861-EP2269992A1 |
| 3861-EP2269993A1 | 3861-EP2270004A1 | 3861-EP2270006A1 |
| 3861-EP2270007A1 | 3861-EP2270008A1 | 3861-EP2272817A1 |
| 3861-EP2272835A1 | 3861-EP2272841A1 | 3861-EP2272844A1 |
| 3861-EP2272847A1 | 3861-EP2275102A1 | 3861-EP2275412A1 |
| 3861-EP2275418A1 | 3861-EP2275420A1 | 3861-EP2277861A1 |
| 3861-EP2277875A2 | 3861-EP2277876A1 | 3861-EP2277877A1 |
| 3861-EP2279741A2 | 3861-EP2279750A1 | 3861-EP2280008A2 |
| 3861-EP2280010A2 | 3861-EP2281559A1 | 3861-EP2281815A1 |
| 3861-EP2281818A1 | 3861-EP2281819A1 | 3861-EP2281824A1 |
| 3861-EP2283811A1 | 3861-EP2284150A2 | 3861-EP2284151A2 |
| 3861-EP2284152A2 | 3861-EP2284153A2 | 3861-EP2284155A2 |
| 3861-EP2284156A2 | 3861-EP2284164A2 | 3861-EP2284169A1 |
| 3861-EP2284170A1 | 3861-EP2284171A1 | 3861-EP2284172A1 |
| 3861-EP2284178A2 | 3861-EP2284179A2 | 3861-EP2287140A2 |
| 3861-EP2287148A2 | 3861-EP2287150A2 | 3861-EP2287161A1 |
| 3861-EP2287162A1 | 3861-EP2287167A1 | 3861-EP2289868A1 |
| 3861-EP2289871A1 | 3861-EP2289876A1 | 3861-EP2289891A2 |
| 3861-EP2292227A2 | 3861-EP2292234A1 | 3861-EP2292590A2 |
| 3861-EP2292595A1 | 3861-EP2292613A1 | 3861-EP2292614A1 |
| 3861-EP2292617A1 | 3861-EP2292619A1 | 3861-EP2295406A1 |
| 3861-EP2295412A1 | 3861-EP2295413A1 | 3861-EP2295416A2 |
| 3861-EP2295419A2 | 3861-EP2295424A1 | 3861-EP2295425A1 |
| 3861-EP2295426A1 | 3861-EP2295427A1 | 3861-EP2295430A2 |
| 3861-EP2295431A2 | 3861-EP2295432A1 | 3861-EP2295437A1 |
| 3861-EP2295439A1 | 3861-EP2295550A2 | 3861-EP2298313A1 |
| 3861-EP2298732A1 | 3861-EP2298734A2 | 3861-EP2298735A1 |
| 3861-EP2298748A2 | 3861-EP2298764A1 | 3861-EP2298765A1 |
| 3861-EP2298768A1 | 3861-EP2298772A1 | 3861-EP2298775A1 |
| 3861-EP2298777A2 | 3861-EP2298778A1 | 3861-EP2300473A2 |
| 3861-EP2301534A1 | 3861-EP2301912A2 | 3861-EP2301913A1 |
| 3861-EP2301914A1 | 3861-EP2301916A2 | 3861-EP2301922A1 |
| 3861-EP2305219A1 | 3861-EP2305260A1 | 3861-EP2305637A2 |
| 3861-EP2305640A2 | 3861-EP2305643A1 | 3861-EP2305659A1 |
| 3861-EP2305660A1 | 3861-EP2305666A1 | 3861-EP2305671A1 |
| 3861-EP2305673A1 | 3861-EP2305680A2 | 3861-EP2305683A1 |
| 3861-EP2308509A1 | 3861-EP2308562A2 | 3861-EP2308812A2 |
| 3861-EP2308828A2 | 3861-EP2308832A1 | 3861-EP2308838A1 |
| 3861-EP2308839A1 | 3861-EP2308844A2 | 3861-EP2308845A2 |
| 3861-EP2308846A2 | 3861-EP2308861A1 | 3861-EP2308863A1 |
| 3861-EP2308872A1 | 3861-EP2308873A1 | 3861-EP2308875A1 |
| 3861-EP2308960A1 | 3861-EP2311451A1 | 3861-EP2311796A1 |
| 3861-EP2311797A1 | 3861-EP2311798A1 | 3861-EP2311799A1 |
| 3861-EP2311818A1 | 3861-EP2311821A1 | 3861-EP2311825A1 |
| 3861-EP2311831A1 | 3861-EP2311834A1 | 3861-EP2311835A1 |
| 3861-EP2311837A1 | 3861-EP2311839A1 | 3861-EP2311841A1 |
| 3861-EP2311842A2 | 3861-EP2314295A1 | 3861-EP2314578A1 |
| 3861-EP2314584A1 | 3861-EP2314589A1 | 3861-EP2316450A1 |
| 3861-EP2316470A2 | 3861-EP2316829A1 | 3861-EP2316832A1 |
| 3861-EP2316833A1 | 3861-EP2316834A1 | 3861-EP2316835A1 |
| 3861-EP2316836A1 | 3861-EP2316837A1 | 3861-EP2371811A2 |
| 3861-EP2374454A1 | CHEBI:29806 | CHEBI:36180 |
| DTXSID9037660 | Fumarate dianion | Fumarate(2-) |
| Fumaric acid, ion(2-) | Fumerate | Q28529698; |
| VZCYOOQTPOCHFL-OWOJBTEDSA-L | but-2-enedioate | fumarate |
| trans-1,2-Ethenedicarboxylic acid | trans-1,2-Ethylenediccarboxylic acid |