Drug
D1283 | monensin
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| TRANSPORT OF PROTONS BUT NOT CHARGE (NA+) | affect | 201 | ||||||
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
 |
Danger |
H300: Fatal if swallowed [Danger Acute toxicity, oral] |
P264, P270, P301+P310, P321, P330, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
  |
Danger |
H301: Toxic if swallowed [Danger Acute toxicity, oral] H316: Causes mild skin irritation [Warning Skin corrosion/irritation] H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation] H371: May cause damage to organs [Warning Specific target organ toxicity, single exposure] |
P260, P264, P270, P280, P301+P310, P305+P351+P338, P309+P311, P321, P330, P332+P313, P337+P313, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| Organism | Test type | Route | Dose (normalized dose) | Effect | Source |
|---|---|---|---|---|---|
| domestic animals - goat/sheep | LD50 | oral | 12mg/kg (12mg/kg) | American Journal of Veterinary Research. Vol. 45, Pg. 1142, 1984. | |
| mouse | LD50 | intraperitoneal | 10mg/kg (10mg/kg) | Drug and Chemical Toxicology. Vol. 8, Pg. 451, 1985. | |
| horse/donkey | LD50 | oral | 2mg/kg (2mg/kg) | American Journal of Veterinary Research. Vol. 42, Pg. 456, 1981. | |
| mouse | LD50 | oral | 43800ug/kg (43.8mg/kg) | "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980Vol. 5, Pg. 472, 1981. | |
| rat | LD50 | oral | 100mg/kg (100mg/kg) | Drug and Chemical Toxicology. Vol. 8, Pg. 451, 1985. | |
| rat | LD50 | intraperitoneal | 15mg/kg (15mg/kg) | Drug and Chemical Toxicology. Vol. 8, Pg. 451, 1985. | |
| (2S,3R,4S)-4-[(2S,5R,7S,8R,9S)-2-{(2S,2'R,3'S,5R,5'R)-2-Ethyl-5'-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyloxan-2-yl]-3'-methyl[2,2'-bioxolan]-5-yl}-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]decan-7-yl]-3-methoxy-2-methylpentanoic acid | (2S,3R,4S)-4-[(2S,5R,7S,8R,9S)-2-{(2S,2'R,3'S,5R,5'R)-2-Ethyl-5'-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyltetrahydro-2H-pyran-2-yl]-3'-methyloctahydro-2,2'-bifuran-5-yl}-9-hydroxy-2,8-di | (2S,3R,4S)-4-[(2S,5R,7S,8R,9S)-2-{(2S,2'R,3'S,5R,5'R)-2-ethyl-5'-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyltetrahydro-2H-pyran-2-yl]-3'-methyloctahydro-2,2'-bifuran-5-yl}-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]dec-7-yl]-3-methoxy-2-methylpentanoic acid |
| (2S,3R,4S)-4-[(3S,5R,7S,8R,9S)-3-[(2R,5S)-5-ethyl-5-[(2R,3S,5R)-5-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-tetrahydropyran-2-yl]-3-methyl-tetrahydrofuran-2-yl]tetrahydrofuran-2-yl]-7-hydroxy-3,8-dimethyl-4,10-dioxaspiro[4.5]decan-9-yl]-3-methoxy-2-methyl-pentanoic acid | 1,6-Dioxaspiro(4.5)decane-7-butyric acid, 2-(5-ethyltetrahydro-5-(tetrahydro-3-methyl-5-(tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl)-2-furyl)-2-furyl)-9-hydroxy-beta-methoxy-alpha,gamma,2,8-tetramethyl- | 1392-52-5 |
| 17090-79-8 | 2-[5-Ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-.beta.-methoxy-.alpha.,.gamma.,2,8-tetramethyl-1,6-dioxaspiro[4.5]decane-7-butyric acid | 906O0YJ6ZP |
| A 3823A | AKOS015964837 | ATCC 15413 |
| BPBio1_000810 | BRD-K55375480-236-03-0 | BSPBio_000736 |
| C06693 | CHEBI:27617 | CHEMBL256105 |
| Coban (as sodium salt) | D08228 | DB11430 |
| DTXSID4048561 | E714 | EINECS 241-154-0 |
| Elancoban | Elancoban [veterinary] (TN) | HSDB 7031 |
| J-010665 | Lilly 673140 | Monelan |
| Monensic acid | Monensin (INN) | Monensin [USAN:USP:INN:BAN] |
| Monensina | Monensina [INN-Spanish] | Monensine |
| Monensinum | Monensinum [INN-Latin] | NSC343257 |
| Prestwick3_000748 | Q3493048 | Rumensin |
| Rumensin (as sodium salt) | Rumensin 90 | SCHEMBL55367 |
| SR-05000013702-2 | Stereoisomer of 2-(2-ethyloctahydro-3'-methyl-5'-(tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl)(2,2'-bifuran-5-yl))-9-hydroxy-beta-methoxy-alpha,gamma,2,8-tetramethyl-1,6-dioxaspiro(4.5)decan-7-butanoic acid | UNII-906O0YJ6ZP |
| ZINC8143466 | monensin | monensin A |
| monensin;Monensin sodium;Monensin, monosodium salt |