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Drug

D1285 | dopamine

Molecular Formula C8H11NO2
Molecular Weight 153.18
Structure
State solid
Route of elimination It has been reported that about 80% of the drug is excreted in the urine within 24 hours, primarily as HVA and its sulfate and glucuronide conjugates and as 3,4-dihydroxyphenylacetic acid. A very small portion is excreted unchanged.
Protein binding No information currently available on protein binding.
Half life 2 minutes
Absorption Dopamine is rapidly absorbed from the small intestine.
Description catecholamine neurotransmitters; precursor to norepinephrine and epinephrine

C

C01CA04 Dopamine


[C01CA] Adrenergic and dopaminergic agents


[C01C] CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES


[C01] CARDIAC THERAPY


[C] Cardiovascular system

Toxicity Dose Time Species Model Method Action Positive criterion Reference
MITOCHONDRIA TRANSPORT 30 nM 2h rat Hippocampal Neurons time-lapse imaging experiments decrease 216

Organism Test type Route Dose (normalized dose) Effect Source
mouse LD50 intraperitoneal 500mg/kg (500mg/kg) National Technical Information Service. Vol. AD277-689,


  • .alpha.-(3,4-Dihydroxyphenyl)-.beta.-aminoethane .beta.-(3,4-Dihydroxyphenyl)ethylamine hydrochloride 1, 4-(2-aminoethyl)-
    1,2-Benzenediol, 4-(2-aminoethyl)- 1,2-Benzenediol, 4-(2-aminoethyl)- (9CI) 1,2-Benzenediol, 4-(2-aminoethyl)-, labeled with tritium
    13510-EP2269989A1 13510-EP2270011A1 13510-EP2272537A2
    13510-EP2272825A2 13510-EP2272847A1 13510-EP2275420A1
    13510-EP2277882A1 13510-EP2280010A2 13510-EP2281559A1
    13510-EP2281815A1 13510-EP2281819A1 13510-EP2284169A1
    13510-EP2284170A1 13510-EP2284171A1 13510-EP2286811A1
    13510-EP2287161A1 13510-EP2287162A1 13510-EP2287165A2
    13510-EP2287166A2 13510-EP2292620A2 13510-EP2295437A1
    13510-EP2295439A1 13510-EP2298312A1 13510-EP2298313A1
    13510-EP2298731A1 13510-EP2298734A2 13510-EP2298758A1
    13510-EP2298759A1 13510-EP2298775A1 13510-EP2298776A1
    13510-EP2301540A1 13510-EP2301933A1 13510-EP2305260A1
    13510-EP2305633A1 13510-EP2305640A2 13510-EP2305644A1
    13510-EP2305648A1 13510-EP2305650A1 13510-EP2305652A2
    13510-EP2305656A1 13510-EP2305659A1 13510-EP2305664A1
    13510-EP2305675A1 13510-EP2305689A1 13510-EP2308828A2
    13510-EP2308867A2 13510-EP2308870A2 13510-EP2308875A1
    13510-EP2311494A1 13510-EP2311801A1 13510-EP2311802A1
    13510-EP2311803A1 13510-EP2311818A1 13510-EP2311827A1
    13510-EP2311828A1 13510-EP2311835A1 13510-EP2314571A2
    13510-EP2316470A2 13510-EP2316836A1 13510-EP2371814A1
    153C5321-5FEE-4B0B-8925-F388F0EEEBD1 2-(3, 4-Dihydroxyphenyl)ethylamine 2-(3,4-Dihydroxyphenyl)-1-ethanamine
    2-(3,4-dihydroxyphenyl) ethylamine 2-(3,4-dihydroxyphenyl)ethylamine 2-(4-Hydroxy-5-oxylatophenyl)-1-ethanaminium
    3,4-DihydroxyphenylA currencythylamin 3,4-Dihydroxyphenylethylamine 3,4-dihydroxyphenethylamine
    3- HYDROXYTYRAMINE 3-Hydroxtyramine 3-Hydroxytyramine
    3-Hydroxytyramine HCl salt 4-(2-Amino-ethyl)-benzene-1,2-diol 4-(2-Aminoethyl)-1,2-benzenediol
    4-(2-Aminoethyl)-1,2-benzenediol # 4-(2-Aminoethyl)-1,2-benzenediol hydrochloride 4-(2-Aminoethyl)-1,2-bezenediol
    4-(2-Aminoethyl)benzene-1,2-diol 4-(2-Aminoethyl)catechol 4-(2-Aminoethyl)pyrocatechol
    4-(2-aminoethyl)-pyrocatechol 4-(2-aminoethyl)pyrocatechol;hydrochloride 4-(2-azanylethyl)benzene-1,2-diol;hydrochloride
    51-61-6 62-31-7 (HYDROCHLORIDE) AB00053463-12
    AB00053463_13 AB00053463_14 AK100905
    AKOS003790978 ANW-54385 ASL 279
    BBL013043 BCP34189 BDBM55121
    BIDD:ER0506 BP-23276 BPBio1_001123
    BSPBio_001932 Biomol-NT_000001 C03758
    CAS-51-61-6 CCG-204675 CHEBI:18243
    CHEMBL59 CTK4E3164 D07870
    DB00988 DSSTox_CID_2420 DSSTox_GSID_22420
    DSSTox_RID_76584 DTXSID6022420 DivK1c_000780
    Dopamin Dopamina Dopamina [INN-Spanish]
    Dopamine (INN) Dopamine (USAN)(*hydrochloride*) Dopamine [INN:BAN]
    Dopamine hydrochloride;dopamine hydrochloride;4-(2-aminoethyl)pyrocatechol hydrobromide Dopaminum Dopaminum [INN-Latin]
    Dophamine EINECS 200-110-0 FS-5341
    FT-0698513 GTPL940 HMS3743I03
    HSDB 3068 Hydroxytyramin IDI1_000780
    IP 498 Intropin (Salt/Mix) Intropin [*hydrochloride*]
    KBio1_000780 KBio2_001492 KBio2_002388
    KBio2_002484 KBio2_004060 KBio2_004956
    KBio2_005052 KBio2_006628 KBio2_007524
    KBio2_007620 KBio3_001152 KBio3_002867
    KBio3_002962 KBioGR_001129 KBioGR_002388
    KBioGR_002484 KBioSS_001492 KBioSS_002393
    KBioSS_002491 KW-3-060 L-DOPAMINE
    L000232 LDP LS-159
    Lopac-H-8502 Lopac0_000586 MCULE-7558764100
    Medopa (TN) NCGC00015519-01 NCGC00015519-02
    NCGC00015519-03 NCGC00015519-04 NCGC00015519-05
    NCGC00015519-07 NCGC00015519-08 NCGC00015519-09
    NCGC00015519-10 NCGC00015519-11 NCGC00096050-01
    NCGC00096050-02 NCGC00096050-03 NCGC00096050-04
    NCGC00096050-05 NINDS_000780 NS00000608
    NSC 173182 NSC-173182 NSC169105
    NSC173182 Oprea1_088821 Oseltamivir-d3;Hydroxytyramin;4-(2-Aminoethyl)benzene-1,2-diol
    Oxytyramine Pyrocatechol, 4-(2-aminoethyl)- Pyrocatechol, 4-(2-aminoethyl)- (8CI)
    Q170304 SBB004044 SBI-0050568.P004
    SCHEMBL8505 SDCCGSBI-0050568.P005 SPBio_001205
    SPECTRUM1505155 SR-01000075366 SR-01000075366-7
    ST048774 STK301601 Sinemet
    Spectrum2_001023 Spectrum3_000406 Spectrum4_000525
    Spectrum5_000945 Spectrum_001012 T7923
    Tox21_110167 Tox21_110167_1 UNII-VTD58H1Z2X
    UPCMLD0ENAT5885989:001 VTD58H1Z2X ZINC33882
    a-(3,4-Dihydroxyphenyl)-b-aminoethane alpha-(3,4-Dihydroxyphenyl)-beta-aminoethane bmse000909
    bmse000933 cMAP_000036 cMAP_000065
    cid_65340 dopamine hydroxytyramine
    intropin m-Hydroxytyramine-

    DrugBank DB00988
    CAS Number 50444-17-2, 51-61-6, 62-31-7, 645-31-8
    PubChem Compound 681