Drug
D1330 | carboxyatractyloside
| Target | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| ADP/ATP translocase 1 | inhibit | 231 | ||||||
| Organism | Test type | Route | Dose (normalized dose) | Effect | Source |
|---|---|---|---|---|---|
| rat | LD50 | intraperitoneal | 2900ug/kg (2.9mg/kg) | Archives of Toxicology. Vol. 32, Pg. 169, 1974. | |
| rat | LD50 | subcutaneous | 2900ug/kg (2.9mg/kg) | JAT, Journal of Applied Toxicology. Vol. 2, Pg. 75, 1982. | |
| mouse | LD50 | subcutaneous | 5400ug/kg (5.4mg/kg) | JAT, Journal of Applied Toxicology. Vol. 2, Pg. 75, 1982. | |
| mouse | LD50 | intraperitoneal | 10600ug/kg (10.6mg/kg) | JAT, Journal of Applied Toxicology. Vol. 2, Pg. 75, 1982. | |
| (1R,4S,7S,9S,10S,13R,15S)-15-hydroxy-7-{[(2R,3R,4R,5R,6R)-6-(hydroxymethyl)-3-[(3-methylbutanoyl)oxy]-4,5-bis(sulfooxy)oxan-2-yl]oxy}-9-methyl-14-methylidenetetracyclo[11.2.1.0^{1,10}.0^{4,9}]hexadecane-5,5-dicarboxylic acid | (2alpha,8alpha,10alpha,13alpha,15beta)-15-hydroxy-2-{[2-O-(3-methylbutanoyl)-3,4-di-O-sulfo-beta-D-glucopyranosyl]oxy}kaur-16-ene-18,19-dioic acid | 15alpha-Hydroxy-2beta-[[2-O-(3-methyl-1-oxobutyl)-3-O,4-O-disulfo-beta-D-glucopyranosyl]oxy]kaur-16-ene-18,19-dioic acid |
| CATR | CS-0017047 | CXT |
| Carboxyatractyloside | GTPL4572 | HY-N1502 |
| Q27075710 | SCHEMBL1612956 |