Compound

D1347 | trolox

Molecular Formula C14H18O4
Molecular Weight 250.29
Structure
Description anti-oxidant ; water-soluble analog of vitamin E

Toxicity Dose Time Species Model Method Action Positive criterion Reference
FERROPTOSIS inhibitor 245

Pictogram Signal Statements Precautionary Statement Codes
Warning

Aggregated GHS information provided by 85 companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.


H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]


H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]


H335 (98.82%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure


Respiratory tract irritation]


Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.


P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)

Organism Test type Route Dose (normalized dose) Effect Source
rabbit LD50 oral > 2gm/kg (2000mg/kg) Journal of the American Oil Chemists' Society. Vol. 52, Pg. 174, 1975.
mouse LD50 intraperitoneal 1700mg/kg (1700mg/kg) Journal of the American Oil Chemists' Society. Vol. 52, Pg. 174, 1975.
rat LD50 oral 4300mg/kg (4300mg/kg) Journal of the American Oil Chemists' Society. Vol. 52, Pg. 174, 1975.
rat LD50 intraperitoneal 1800mg/kg (1800mg/kg) Journal of the American Oil Chemists' Society. Vol. 52, Pg. 174, 1975.
mouse LD50 oral 1630mg/kg (1630mg/kg) Journal of the American Oil Chemists' Society. Vol. 52, Pg. 174, 1975.
mouse LD50 subcutaneous 1930mg/kg (1930mg/kg) Journal of the American Oil Chemists' Society. Vol. 52, Pg. 174, 1975.


  • (+/-)- 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (+/-)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid (+/-)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid, 97%
    (+/-)-6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (2R)-6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydrochromene-2-carboxylic acid (2S)-6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydrochromene-2-carboxylic acid
    (6-hydroxy-2,5,7,8-tetramethylchroman-2-yl)carboxylic acid 2H-1-Benzopyran-2-carboxylic acid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl- 2H-1-Benzopyran-2-carboxylic acid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-, (+-)-
    2H-1-Benzopyran-2-carboxylicacid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl- 3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzo-pyran-2-carboxylic Acid 3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxylic acid
    53188-07-1 56305-04-5 6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-2-CARBOXYLICACID
    6-Hydroxy-2,5,7,8-tetramethyl-2-chromancarboxylic acid 6-Hydroxy-2,5,7,8-tetramethyl-2-chromanecarboxylic acid # 6-Hydroxy-2,5,7,8-tetramethyl-chroman-2-carboxylic acid
    6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid 6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid 6-hydroxy-2,5,7,8-tetramethychroman-2-carboxylic acid
    6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid 6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-chromene-2-carboxylic acid 6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydrochromene-2-carboxylic acid
    6-hydroxy-2,5,7,8-tetramethyl-chromane-2-carboxylic acid 6-hydroxy-3,4-dihydro-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxylic acid ACMC-1ATBW
    ACMC-20apju AK116067 AKOS015856256
    ANW-31653 API0004530 AS-30121
    AX8109302 BBL103047 BCP16474
    BDBM50359629 BPBio1_000571 BRD-A17846016-001-03-0
    BRD-A17846016-001-07-1 BRN 5052542 BSPBio_000519
    C-30819 CC-22776 CCG-207912
    CHEBI:82625 CHEMBL153 CS-8035
    CTK1H0082 DB-052268 DB-071631
    DTXSID60866306 EINECS 258-422-8 FT-0621156
    FT-0770514 GEO-03688 HMS1569J21
    HMS2096J21 HMS2230A15 HMS3369E20
    HMS3713J21 HY-101445 KS-000015YX
    LS-39163 MCULE-8649288753 MFCD00006846
    MLS002153860 NCGC00179534-01 NS00015501
    Oprea1_727377 Prestwick0_000530 Prestwick1_000530
    Prestwick2_000530 Prestwick3_000530 Prestwick_855
    Q245489 SBB005933 SC-94697
    SCHEMBL3226 SMR001233218 SPBio_002440
    SR-01000841227 SR-01000841227-2 ST057520
    STL556856 TROLOX C Trolox®
    Trolox(R), 97% Trolox(TM) s3665
    trolox

    CAS Number 53101-49-8, 53174-06-4, 53188-07-1, 56305-04-5
    PubChem Compound 40634