Compound

D1352 | JX06

Molecular Formula C10H16N2O2S4
Molecular Weight 324.5
Structure
Description a potent, selective and covalent pyruvate dehydrogenase kinase (PDK) 1/2/3 inhibitor with IC50 values of 49, 101 and 313 nM for PDK1, PDK2 and PDK3, respectively.

Organism Test type Route Dose (normalized dose) Effect Source
mouse LD50 oral 3250mg/kg (3250mg/kg) Archives Internationales de Pharmacodynamie et de Therapie. Vol. 112, Pg. 36, 1957.


  • 4,4'-(Dithiodicarbonothioyl)bismorpholine 4,4'-(Dithiodicarbonothioyl)dimorpholine 4-27-00-00313 (Beilstein Handbook Reference)
    4-Morpholinethiocarbonyl disulfide 729-46-4 72G763P0UO
    AI3-01690 AKOS016036660 BDBM50414944
    BRN 0276307 Bis(4-morpholinothiocarbonyl) disulfide Bis(morpholinothiocarbonyl) disulfide
    Bis(morpholinothiocarbonyl)disulfide CHEMBL121556 CS-0015656
    CTK5D7131 DISULFIDE, BIS(MORPHOLINOTHIOCARBONYL) DTXSID4052471
    Di(4-morpholinyl)dithioperoxyanhydride Dimorpholinethiuram disulfide Disulfide, bis(4-morpholinylthioxomethyl)
    Dithiobis(morpholinomethanethione) EINECS 211-980-6 HY-19564
    JX 06 JX06 LS-63065
    MCULE-5911488808 MLS003171519 Morpholine, 4,4'-(dithiodicarbonothioyl)bis-
    Morpholine,4'-(dithiodicarbonothioyl)bis- Morpholine,4,4'-(dithiodicarbonothioyl)bis- NS00037445
    NSC 402538 NSC-402538 NSC402538
    Q27266070 SCHEMBL11172136 SMR001875403
    Thiuram disulfide, bis(oxydi-2,1-ethanediyl)- Thiuram disulfide,1-ethanediyl)- UNII-72G763P0UO
    ZINC1594973 morpholine-4-carbothioylsulfanyl morpholine-4-carbodithioate

    CAS Number 729-46-4
    PubChem Compound 12892

    1. https://www.bocsci.com/jx-06-cas-729-46-4-item-169680.html?nid=1477