MITOTOX

Compound

D1353 | ZLN005

Properties

Molecular Formula	C17H18N2
Molecular Weight	250.34
Structure
Description	Selective transcriptional regulator of peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha).

Therapeutic Classification Source: DrugBank

Mitochondrial Toxicity Evaulation

Toxicity	Dose	Time	Species	Model	Method	Action	Positive criterion	Reference
SIGNALING								260

Targets

Target	Dose	Time	Species	Model	Method	Action	Positive criterion	Reference
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha								260

GHS Hazard Tables Source: PubChem

Pictogram	Signal	Statements	Precautionary Statement Codes
	Warning	Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H413 (100%): May cause long lasting harmful effects to aquatic life [Hazardous to the aquatic environment, long-term hazard] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.	P264, P270, P273, P280, P301+P312, P305+P351+P338, P330, P337+P313, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)

Pictogram

Signal

Statements

Precautionary Statement Codes

Warning

Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

H413 (100%): May cause long lasting harmful effects to aquatic life [Hazardous to the aquatic environment, long-term hazard]

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.

P264, P270, P273, P280, P301+P312, P305+P351+P338, P330, P337+P313, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)

Indications Source: SIDER

Synonyms Source: PubChem

(1S,2R,3R,5S,6S,16E,18E,20R,21S)-11-Chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracycl o[19.3.1.110,14.03,5]hexacosa-10(26),11,13,16,18-pentaen-6-yl 2- methylpropanoate	1H-Benzimidazole, 2-[4-(1,1-dimethylethyl)phenyl]-	2-(4-(tert-butyl)phenyl)-1H-benzo[d]imidazole
2-(4-t-butylphenyl) benzimidazole	2-(4-tert-Butylphenyl)-1H-benzoimidazole	2-(4-tert-butylphenyl)-1H-benzimidazole
2-(4-tert-butylphenyl)-1H-benzo[d]imidazole	2-[4-(tert-butyl)phenyl]-1H-1,3-benzimidazole	2-[4-(tert-butyl)phenyl]benzimidazole
49671-76-3	A13734	AB0098402
AK175832	AKOS003029495	AOB6265
AS-55878	BCP08848	BIM-0034399.P001
CBMicro_034305	CCG-266970	CHEMBL4303368
CS-2189	CTK1C6843	DA-05489
DTXSID60358473	EX-A690	FT-0700319
HMS3653P03	HY-17538	J-690308
KS-00001D9B	MCULE-2572912092	NCGC00371152-01
QC-11350	SCHEMBL6755306	ST50431739
STK395157	SW219815-1	ZINC477459
ZLN 005	ZLN-005 pound>>ZLN 005	ZLN005
s7447

External IDs

CAS Number	4529-96-8, 462-26-0, 49671-76-3
PubChem Compound	899323