Drug

D1367 | 3-methyladenine

Molecular Formula C6H7N5
Molecular Weight 149.15
Structure
State solid
Description PI3K inhibitor; autophagy inhibitor

Toxicity Dose Time Species Model Method Action Positive criterion Reference
MITOPHAGY 10 mM SH-SY5Y neuroblastoma cells Mitochondrial population levels were determined by flow cytometry using MitoTracker Deep Red (MTDR) dye. 252

Pictogram Signal Statements Precautionary Statement Codes
Warning

Aggregated GHS information provided by 2 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.


H302 (50%): Harmful if swallowed [Warning Acute toxicity, oral]


H315 (50%): Causes skin irritation [Warning Skin corrosion/irritation]


H319 (50%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]


Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.


P264, P270, P280, P301+P312, P302+P352, P305+P351+P338, P321, P330, P332+P313, P337+P313, P362, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)


  • 1p7m 3-MA 3-METHYL-3H-PURIN-6-YLAMINE
    3-Methyl-3H-adenine 3-Methyl-3H-purin-6-amine 3-Methyl-3H-purin-6-amine #
    3-Methyl-7H-purine-6(3H)-imine 3-Methyladenine (3-MA) 3-Methyladenine autophagy inhibitor
    3-Methyladenine, 90+% 3-Methyladenine, autophagy inhibitor 3-Methyladenine?
    3-methyl-3,9-dihydro-6H-purin-6-imine 3-methyl-3-hydropurin-6-imine 3-methyl-3-hydropurine-6-ylamine
    3-methyl-3H-adenine;3-Methyladenin 3-methyl-3H-purin-6-amine (ACD/Name 4.0) 3-methyl-3H-purin-6-ylamine (ACD/Name 4.0)
    3-methyl-7H-purin-6-imine 3-methyl-Adenine 3-methyladenin
    3-methyladenine 3-methylpurin-6-amine 3H-Purin-6-amine, 3-methyl-
    3H-Purin-6-amine,3-methyl- 3MA 3mea
    4ai5 5-26-17-00151 (Beilstein Handbook Reference) 5142-23-4
    6-Amino-3-methylpurine 60192-57-6 A7582
    AB0007938 ABP000334 AC-28818
    ACN-001131 ACN-C001131 ADENINE, 3-METHYL-
    AK-94088 AKOS003382321 AKOS006228458
    ANW-54285 AOB2548 AS-19224
    AX8088144 BCP02452 BDBM50488841
    BRD-K81647657-001-01-9 BRN 0146087 Bio1_000422
    Bio1_000911 Bio1_001400 C-02699
    C00913 CC-15589 CCG-206388
    CHEBI:38635 CHEMBL292268 CHEMBL4303725
    CS-5207 CTK4J4217 CTK6I3368
    DB-051961 DB04104 DTXSID80199406
    EINECS 225-908-6 EX-A130 FCH1110982
    FT-0635560 FT-0671432 GL3599
    HMS3656P04 HY-19312 J-640198
    J-800199 KS-00000NOD LS-15078
    M2518 MCULE-5086156902 MFCD00010531
    MLS006010995 NCGC00345447-02 NCIOpen2_000270
    NS00005696 NSC 66389 NSC 66389 (3-MA)
    NSC-66389 NSC66389 Q-9331
    Q27094948 QC-518 SBB086626
    SCHEMBL15764619 SCHEMBL254058 SCHEMBL48369
    SMR002530641 ST50298916 SW220216-1
    SY026559 VZ27096 W-202935
    X5709 ZINC100003619 ZINC403086
    n3-methyladenine s2767

    DrugBank DB04104
    CAS Number 5142-23-4, 5360-74-7, 60192-57-6
    PubChem Compound 135398661