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Drug

D1383 | mimosine

Molecular Formula C8H10N2O4
Molecular Weight 198.18
Structure
State solid
Protein binding >99.5%
Description a non-protein amino acid similar to tyrosine; have anti-cancer, anti-inflammatory, anti-fibrotic, anti-viral, herbicidal, and insecticidal properties; induces caspase‑9‑mediated apoptosis

Toxicity Dose Time Species Model Method Action Positive criterion Reference
APOPTOSIS 0.3 mM U-937 leukemia cell line. 270


  • (+/-)-mimosine (2S)-2-amino-3-(3-hydroxy-4-oxohydropyridyl)propanoic acid (2S)-2-amino-3-(3-hydroxy-4-oxopyridin-1-yl)propanoic acid
    (S)-a-amino-3-hydroxy-4-oxo-1(4H)-pyridylpropionic acid .beta.-[N-(3-Hydroxy-4-pyridone)]-.alpha.-aminopropionic acid 1(4H)-Pyridinealanine, 3-hydroxy-4-oxo-
    1(4H)-Pyridinepropanoic acid, (S)- 1(4H)-Pyridinepropanoic acid, .alpha.-amino-3-hydroxy-4-oxo-, (.alpha.S)- 1(4H)-Pyridinepropanoic acid, alpha-amino-3-hydroxy-4-oxo-
    1(4H)-Pyridinepropanoic acid, alpha-amino-3-hydroxy-4-oxo-, (+-)- 1(4H)-Pyridinepropionic acid, .alpha.-amino-3-hydroxy-4-oxo- 1-L-alpha-Aminopropionil, 3-hydroxi, 4-oxopiridina [Spanish]
    10182-82-8 2-AMINO-3-(3-HYDROXY-4-OXO-PYRIDIN-1-YL)PROPANOIC ACID 2-amino-3-(3-hydroxy-4-oxo-1,4-dihydropyridin-1-yl)propanoic acid
    2-amino-3-(3-hydroxy-4-oxo-1H-pyridin-1-yl)-propanoic acid 2-amino-3-(3-hydroxy-4-oxohydropyridyl)propanoic acid 2-amino-3-(3-hydroxy-4-oxopyridin-1(4H)-yl)propanoic acid
    2116-55-4 27678-82-6 3-(3-Hydroxy-4-oxopyridin-1(4H)-yl)alanine
    AKOS006228368 BCP13303 BSPBio_002244
    CCG-38561 CHEBI:95190 CHEMBL251433
    CS-0119397 CTK4A0280 DTXSID80950337
    DivK1c_001000 FT-0627961 HMS1569K19
    HMS1921M08 HMS3744K15 HMS503G21
    IDI1_001000 KBio1_001000 KBio2_000767
    KBio2_003335 KBio2_005903 KBio3_001464
    KBioGR_000440 KBioSS_000767 LS-131932
    Leucena glauca .alpha.-amino acid Leucenine;Leucenol MCULE-6953076060
    Mimosine Mimosine, (+/-)- NCGC00094870-01
    NCGC00094870-02 NCGC00094870-03 NCGC00178740-01
    NCI60_032990 NINDS_001000 NS00043037
    NS00068434 NSC-159548 NSC-69188
    NSC159548 NSC69188 Prestwick0_000379
    Prestwick1_000379 Prestwick2_000379 Prestwick_830
    Q27166999 SBB000370 SCHEMBL41924
    SDCCGMLS-0066728.P001 SPBio_000691 SPBio_002458
    SPECTRUM1500869 ST056312 STL564778
    Spectrum2_000656 Spectrum3_000722 Spectrum4_000110
    Spectrum5_001484 Spectrum_000287 WLN: T6N DVJ A1YZVQ CQ
    alpha-Amino-1,4-dihydro-3-hydroxy-4-oxopyridine-1-propionic acid beta-(N-(3-Hydroxy-4-pyridone))-alpha-aminopropionic acid beta-[N-(3-Hydroxy-4-pyridone)]-alpha-aminopropionic Acid

    DrugBank DB01055
    CAS Number 10182-82-8, 2116-55-4, 27678-82-6, 500-44-7
    PubChem Compound 3862