MITOTOX

Compound

D1396 | Tetramethylpyrazine

Properties

Molecular Formula	C8H12N2
Molecular Weight	136.19
Structure
Trade names	Ligustrazine; Tetrapyrazine
Description	alkylpyrazine; a chemical compound found in nattō and in fermented cocoa beans

Therapeutic Classification Source: DrugBank

Targets

Target	Dose	Time	Species	Model	Method	Action	Positive criterion	Reference
Mitofusin-1		48hr		Mfn1−/− MEFs stably expressing an Mfn1 promoter reporter construct	Relative luciferase activity was determined in Mfn1−/− MEFs carrying the Mfn1 promoter reporter	down regulate		276

GHS Hazard Tables Source: PubChem

Pictogram	Signal	Statements	Precautionary Statement Codes
	Warning	Aggregated GHS information provided by 1678 companies from 6 notifications to the ECHA C&L Inventory. H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.	P264, P270, P301+P312, P330, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)
	Warning	H302: Harmful if swallowed [Warning Acute toxicity, oral]	P264, P270, P301+P312, P330, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)

Pictogram

Signal

Statements

Precautionary Statement Codes

Warning

Aggregated GHS information provided by 1678 companies from 6 notifications to the ECHA C&L Inventory.

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.

P264, P270, P301+P312, P330, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)

Warning

H302: Harmful if swallowed [Warning Acute toxicity, oral]