MITOTOX

Compound

D1403 | Gingerol

Properties

Molecular Formula	C17H26O4
Molecular Weight	294.4
Structure
Description	a phenol phytochemical compound found in fresh ginger that activates spice receptors on the tongue

Therapeutic Classification Source: DrugBank

Mitochondrial Toxicity Evaulation

Toxicity	Dose	Time	Species	Model	Method	Action	Positive criterion	Reference
AUTOPHAGY	1µM	overnight		HeLa cells	Cyto-ID Autophagy Detection dye and Autophagy compound library in a microplate-based assay	induce	>2 fold increase	277

GHS Hazard Tables Source: PubChem

Pictogram	Signal	Statements	Precautionary Statement Codes
	Danger	Aggregated GHS information provided by 68 companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. H301 (58.82%): Toxic if swallowed [Danger Acute toxicity, oral] H302 (38.24%): Harmful if swallowed [Warning Acute toxicity, oral] H312 (39.71%): Harmful in contact with skin [Warning Acute toxicity, dermal] H315 (98.53%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (98.53%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H332 (39.71%): Harmful if inhaled [Warning Acute toxicity, inhalation] H335 (97.06%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure Respiratory tract irritation] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.	P261, P264, P270, P271, P280, P301+P310, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)

Pictogram

Signal

Statements

Precautionary Statement Codes

Danger

Aggregated GHS information provided by 68 companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

H301 (58.82%): Toxic if swallowed [Danger Acute toxicity, oral]

H302 (38.24%): Harmful if swallowed [Warning Acute toxicity, oral]

H312 (39.71%): Harmful in contact with skin [Warning Acute toxicity, dermal]

H315 (98.53%): Causes skin irritation [Warning Skin corrosion/irritation]

H319 (98.53%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

H332 (39.71%): Harmful if inhaled [Warning Acute toxicity, inhalation]

H335 (97.06%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure

Respiratory tract irritation]

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.

P261, P264, P270, P271, P280, P301+P310, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)

Indications Source: SIDER

Synonyms Source: PubChem

6- Gingerol

External IDs

CAS Number	1391-73-7, 23513-14-6, 58253-27-3
PubChem Compound	442793