Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
STATE 3 RESPIRATION | I50=100, 160, 160, 170, 150 μM for substrates Glutamate/Malate, Pyruvate/Malate, Ornithine/Malate, Arginine/Malate and Succinate repectively | rat | liver mitochondria | Clark electrode | inhibit | 303 | ||