Drug
D1441 | Benznidazole
P
P01CA02 Benznidazole
[P01CA] Nitroimidazole derivatives
[P01C] AGENTS AGAINST LEISHMANIASIS AND TRYPANOSOMIASIS
[P01] ANTIPROTOZOALS
[P] Antiparasitic products, insecticides and repellents
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| TRANSMEMBRANE POTENTIAL | 34μM | Epimastigote forms of Trypanosoma cruzi of Y strain, | measured by flow cytometry using JC-1 dye (BD MitoScreen kit) | decrease | IC50 | 305 | ||