MITOTOX

Compound

D1477 | Monastrol

Structure
Description	inhibit the kinesin-5 (KIF11 or Kinesin Eg5, a motor protein important for spindle bipolarity)

Toxicity	Dose	Time	Species	Model	Method	Action	Positive criterion	Reference
GLUCOSE GALACTOSE IC50 RATIO				permeabilized LUHMES cells	Assessment of the function of individual mitochondrial complexes using Agilent Seahorse XFe24	Negative	EC25(NA) [Glc/Gal]	326