Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
---|---|---|---|---|---|---|---|---|
MITOCHONDRIAL FATTY ACID BETA OXIDATION | <0.05/0.04 | human/rat | hepatocytes | Fatty acid oxidation (FAO) was determined by measuring 14CO2 release from 14C-labeled palmitate | inhibition | IC50 (μM) | 333 | |
SYNTHESIS OF KETONE BODY | 0.31 | Wistar rat | hepatocytes | ketone bodies (KB = β-hydroxybutyrate + acetoacetate) were determined with a commercially available kit (Autokit 3-HB from Wako) | inhibition | IC50 (μM) | 333 | |
2-tetradecylglycidic acid | McN-3802 | Palmoxiric acid |
PubChem Compound | 71976 |