MITOTOX

Compound

D0130 | 2-Acetylaminofluorene

Properties

Molecular Formula	C15H13NO
Molecular Weight	223.27
Structure

Therapeutic Classification Source: DrugBank

Mitochondrial Toxicity Evaulation

Toxicity	Dose	Species	Model	Method	Action	Positive criterion	Reference
MEMBRANE POTENTIAL	36.27±10.50	human	qHTS-HepG2	MMP assay	decrease	IC50	163
MEMBRANE POTENTIAL	31.62	human	HepG2	MMP assay	decrease	IC50	163
MEMBRANE POTENTIAL		rat	hepatocytes	MMP assay	Negative	IC50	163

GHS Hazard Tables Source: PubChem

Pictogram	Signal	Statements	Precautionary Statement Codes
	Danger	Aggregated GHS information provided by 42 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. H302 (92.86%): Harmful if swallowed [Warning Acute toxicity, oral] H350 (90.48%): May cause cancer [Danger Carcinogenicity] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.	P201, P202, P264, P270, P281, P301+P312, P308+P313, P330, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)

Pictogram

Signal

Statements

Precautionary Statement Codes

Danger

Aggregated GHS information provided by 42 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

H302 (92.86%): Harmful if swallowed [Warning Acute toxicity, oral]

H350 (90.48%): May cause cancer [Danger Carcinogenicity]

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.

P201, P202, P264, P270, P281, P301+P312, P308+P313, P330, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.)

Indications Source: SIDER

Synonyms Source: PubChem

2-(Acetylamino)fluorene	2-AAF	2-ACETYLAMINOFLUORENE-3-YL
2-Acetamidofluorene	2-Acetamidofluorene, 95%	2-Acetaminofluorene
2-Acetoaminofluorene	2-Acetylaminfluorene	2-Acetylamino-fluoren
2-Acetylamino-fluoren [German]	2-Acetylaminofluorene	2-Acetylaminofluorene;2-AAF;2 Fluorenylacetamide;Fluoren-2-ylacetamide
2-Acetylaminofluorine	2-Aminoacetylfluorene	2-FAA
2-Fluorenil acetamide	2-Fluorenylacetamide	2-acetylaminoflourene
5024AF	53-96-3	9M98QLJ2DL
A0076	AAF	ACETYLAMINOFLUORENE
ACMC-209lbc	AFF	AI3-52433
AKOS004006242	ANW-31894	Acetamide, N-9H-fluoren-2-yl-
Acetamide, N-fluoren-2-yl-	Acetoaminofluorene	Azetylaminofluoren
Azetylaminofluoren [German]	BBL001828	BCP30181
BRD-K63993117-001-01-3	BRN 2807677	C-12543
C02778	CAS-53-96-3	CC-08502
CCG-231696	CCRIS 1	CHEBI:17356
CHEMBL311469	CTK3J0353	CZIHNRWJTSTCEX-UHFFFAOYSA-N
DB-020315	DSSTox_CID_18	DSSTox_GSID_39227
DSSTox_RID_79424	DTXSID0039227	EINECS 200-188-6
FT-0631234	Fluorene, 2-acetamido-	Fluorenylacetamide
HSDB 4077	InChI=1/C15H13NO/c1-10(17)16-13-6-7-15-12(9-13)8-11-4-2-3-5-14(11)15/h2-7,9H,8H2,1H3,(H,16,17	KS-000017GW
LS-188	MCULE-6066498727	N-(2-Fluorenyl)acetamide
N-(2-Fluorenyl)acetamide, >=98% (HPLC)	N-(9H-Fluoren-2-yl)acetamide	N-2-Fluorenyl Acetamide
N-2-Fluorenylacetamide	N-9H-Fluoren-2-ylacetamide	N-9H-fluoren-2-yl-Acetamide
N-Fluoren-2-yl acetamide	N-Fluoren-2-ylacetamide	N-acetyl-2-aminofluorene
NCGC00188968-01	NCGC00188968-02	NCGC00258384-01
NSC 12279	NSC-12279	NSC12279
Oprea1_431359	Q4382200	RCRA waste no. U005
RCRA waste number U005	RTR-031363	SBB056657
SCHEMBL75140	SEL11071160	SR-01000394055
SR-01000394055-1	ST50308153	STK386197
T7962	TR-031363	TRA0066210
Tox21_200830	UNII-9M98QLJ2DL	WLN: L B656 HHJ EMV1
ZINC154557

External IDs

CAS Number	53-96-3, 55281-94-2
PubChem Compound	5897
KEGG Compound ID	C02778
ChEBI	17356
ChemSpider	5686
Wikipedia	2-Acetylaminofluorene

References

1. Balansky et al. 1996