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F0108 | Membrane potential


Transmembrane potential >> membrane potential

Compound Dose Time Species Model Method Action Result Positive criterion Reference
benzbromarone 1 μmol/L 1 hour rat; Sprague–Dawley hepatocytes Measurement of mitochondrial membrane potential decrease Positive p < 0.01 4
benzbromarone 4 μmol/L 1 hour rat; Sprague–Dawley hepatocytes Measurement of mitochondrial membrane potential decrease Positive p < 0.01 4
benzbromarone 8 μmol/L 1 hour rat; Sprague–Dawley hepatocytes Measurement of mitochondrial membrane potential decrease Positive p < 0.01 4
benzbromarone 20 μmol/L 1 hour rat; Sprague–Dawley hepatocytes Measurement of mitochondrial membrane potential decrease Positive p < 0.01 4
Amiodarone 8 μmol/L 1 hour rat; Sprague–Dawley hepatocytes Measurement of mitochondrial membrane potential decrease Positive p < 0.05 4
Amiodarone 20 μmol/L 1 hour rat; Sprague–Dawley hepatocytes Measurement of mitochondrial membrane potential decrease Positive p < 0.01 4
benzarone 8 μmol/L 1 hour rat; Sprague–Dawley hepatocytes Measurement of mitochondrial membrane potential decrease Positive p < 0.01 4
benzarone 20 μmol/L 1 hour rat; Sprague–Dawley hepatocytes Measurement of mitochondrial membrane potential decrease Positive p < 0.01 4
Diclofenac 50 μmol/L 3 minutes rat liver mitochondria Assessment of Mitochondrial Membrane Potential; incubated in the presence of Ca2+ decrease Positive p < 0.01 6
Diclofenac 250 μmol/L 24 hours rat hepatocytes Assessment of Mitochondrial Membrane Potential decrease Positive p < 0.01 6
Diclofenac 500 μmol/L 24 hours rat hepatocytes Assessment of Mitochondrial Membrane Potential decrease Positive p < 0.01 6
Metformin 1 mM 24 hours human hepatocytes Measurement of mitochondrial membrane potential decrease Positive 15
Metformin 2 mM 24 hours human hepatocytes Measurement of mitochondrial membrane potential decrease Positive 15
buformin 75 μM 24 hours human hepatocytes Measurement of mitochondrial membrane potential decrease Positive 15
Phenformin 12.5 μM 24 hours human hepatocytes Measurement of mitochondrial membrane potential decrease Positive 15
Perhexiline 200 μM mouse; Crl/CD-l(1CR)BR Swiss liver mitochondria Measurement of mitochondrial membrane potential decrease Positive 193
(1,1,3,3-tetramethylbutyl)phenol 2.85±0.86 human qHTS-HepG2 MMP assay decrease Positive IC50 163
(1'-ethyl-6,7-dihydro-5h-spiro[furo[2,3-f]indole-3,4'-piperidin]-5-yl)[2'-methyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-yl]methanone hydrochloride 6.09±2.54 human qHTS-HepG2 MMP assay decrease Positive IC50 163
(2-ethyl-4-{[(4-{[4-(4-methoxyphenyl)piperazin-1-yl]methyl}-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl)methyl]sulfanyl}phenoxy)acetic acid 25.29±5.81 human qHTS-HepG2 MMP assay decrease Positive IC50 163
(2-nitro-1-propenyl)benzene 38.57±15.32 human qHTS-HepG2 MMP assay decrease Positive IC50 163
(5-chloro-2-hydroxyphenyl)phenylmethanone 29.09±3.36 human qHTS-HepG2 MMP assay decrease Positive IC50 163
(5s,8s)-5-(3,4-dichlorophenyl)-8-(methylamino)-5,6,7,8-tetrahydronaphthalene-2-sulfonamide 8.31±1.43 human qHTS-HepG2 MMP assay decrease Positive IC50 163
(9z)-octadec-9-enamide 41.61±7.16 human qHTS-HepG2 MMP assay decrease Positive IC50 163
(acryloyloxy)(tributyl)stannane 0.19±0.11 human qHTS-HepG2 MMP assay decrease Positive IC50 163
(n-6)-methyladenine 5.98±5.84 human qHTS-HepG2 MMP assay decrease Positive IC50 163
1-(2,3,8,8-tetramethyl-1,2,3,4,5,6,7,8-octahydronaphthalen-2-yl)ethanone 27.31±20.44 human qHTS-HepG2 MMP assay decrease Positive IC50 163
1-(3,5,5,6,8,8-hexamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethanone 30.64±18.87 human qHTS-HepG2 MMP assay decrease Positive IC50 163
1,1,1-trichloropropanone 1.22±0.56 human qHTS-HepG2 MMP assay decrease Positive IC50 163
1,1,2-trimethyl-1h-benzo[e]indole 23.42±4.03 human qHTS-HepG2 MMP assay decrease Positive IC50 163
1,1':3',1''-terphenyl 47.88±14.29 human qHTS-HepG2 MMP assay decrease Positive IC50 163
1,2,5,6,9,10-hexabromocyclododecane 6.93±1.95 human qHTS-HepG2 MMP assay decrease Positive IC50 163
1,2-benzisothiazolin-3-one 38.57±13.65 human qHTS-HepG2 MMP assay decrease Positive IC50 163
1,2-phenylenediamine 3.90±3.61 human qHTS-HepG2 MMP assay decrease Positive IC50 163
1,2-phenylenediamine dihydrochloride 0.44±0.20 human qHTS-HepG2 MMP assay decrease Positive IC50 163
1,3,5-tris(4-tert-butyl-3-hydroxy-2,6-dimethylbenzyl)-1,3,5-triazinane-2,4,6-trione 12.20±2.84 human qHTS-HepG2 MMP assay decrease Positive IC50 163
1,3-didecyl-2-methylimidazolium chloride 3.86±4.19 human qHTS-HepG2 MMP assay decrease Positive IC50 163
1,3-diiminobenz(f)isoindoline 11.08±7.81 human qHTS-HepG2 MMP assay decrease Positive IC50 163
1,3-diphenyl-1,3-propanedione 11.68±1.35 human qHTS-HepG2 MMP assay decrease Positive IC50 163
1,4-benzenediamine 3.28±0.42 human qHTS-HepG2 MMP assay decrease Positive IC50 163
1,4-diaminoanthraquinone 0.03±0.01 human qHTS-HepG2 MMP assay decrease Positive IC50 163
1,4-dihydroxyanthracene-9,10-dione 5.24±3.43 human qHTS-HepG2 MMP assay decrease Positive IC50 163
1,4-naphthalenediamine 0.20±0.08 human qHTS-HepG2 MMP assay decrease Positive IC50 163
1,5-naphthalenediamine 17.00±19.61 human qHTS-HepG2 MMP assay decrease Positive IC50 163
1,8-dihydroxy-4,5-dinitroanthraquinone 0.07±0.04 human qHTS-HepG2 MMP assay decrease Positive IC50 163
10-chloro-9-anthraldehyde 13.87±7.82 human qHTS-HepG2 MMP assay decrease Positive IC50 163
Mito-4509 37.81±13.89 human qHTS-HepG2 MMP assay decrease Positive IC50 163
17alpha-ethinylestradiol 19.12±5.99 human qHTS-HepG2 MMP assay decrease Positive IC50 163
1-amino-2,4-dibromoanthraquinone 2.78±3.75 human qHTS-HepG2 MMP assay decrease Positive IC50 163
1-amino-2-methylanthraquinone 0.64±0.08 human qHTS-HepG2 MMP assay decrease Positive IC50 163
1-benzyl-1-{[3-(4-chlorophenyl)-5-methyl-1-benzofuran-2-yl]methyl}-3-(2,4,6-trifluorophenyl)urea 21.01±2.43 human qHTS-HepG2 MMP assay decrease Positive IC50 163
1-decyl-3-methylimidazolium tetrafluoroborate 3.87±16.67 human qHTS-HepG2 MMP assay decrease Positive IC50 163
1-decyl-3-methylimidazolium trifluoromethanesulfonate 1.67±2.71 human qHTS-HepG2 MMP assay decrease Positive IC50 163
1-dodecyl-3-methylimidazolium hexafluorophosphate 3.71±8.52 human qHTS-HepG2 MMP assay decrease Positive IC50 163
1-fluoro-2,4-dinitrobenzene 3.71±0.60 human qHTS-HepG2 MMP assay decrease Positive IC50 163
1h,3h-naphtho(1,8-cd)pyran-1,3-dione 3.89±1.12 human qHTS-HepG2 MMP assay decrease Positive IC50 163
1h-benzo[de]isoquinoline-1,3(2h)-dione 8.31±3.47 human qHTS-HepG2 MMP assay decrease Positive IC50 163
1h-indole-2-carboxamide, n-[(3r)-1-(2-fluorophenyl)-3,4,6,7-tetrahydro-4-oxopyrrolo[3,2,1-jk][1,4]benzodiazepin-3-yl]- 8.41±0.00 human qHTS-HepG2 MMP assay decrease Positive IC50 163
1-hydroxypyrene 4.67±1.95 human qHTS-HepG2 MMP assay decrease Positive IC50 163
1-isocyanato-3-(trifluoromethyl)benzene 3.28±1.13 human qHTS-HepG2 MMP assay decrease Positive IC50 163
1-methyl-3-octylimidazolium hexafluorophosphate 8.23±5.05 human qHTS-HepG2 MMP assay decrease Positive IC50 163
1-methyl-3-octylimidazolium tetrafluoroborate 5.66±5.82 human qHTS-HepG2 MMP assay decrease Positive IC50 163
1-methyl-3-octylimidazolium trifluoromethanesulfonate 8.38±4.29 human qHTS-HepG2 MMP assay decrease Positive IC50 163
1-methylpyrene 43.23±4.99 human qHTS-HepG2 MMP assay decrease Positive IC50 163
1-naphthol 31.04±5.96 human qHTS-HepG2 MMP assay decrease Positive IC50 163
1-nitronaphthalene 59.74±7.06 human qHTS-HepG2 MMP assay decrease Positive IC50 163
1-nitropyrene 2.01±2.06 human qHTS-HepG2 MMP assay decrease Positive IC50 163
Edaravone 31.75±4.28 human qHTS-HepG2 MMP assay decrease Positive IC50 163
1-trans-delta-9-tetrahydrocannabinol 4.99±1.66 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2-(4-hydroxybenzyl)phenol 27.47±1.92 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2-(butan-2-yl)phenol 49.48±9.45 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2-(thiocyanomethylthio)benzothiazole 33.08±4.58 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2,2',4,4',5-pentabromodiphenyl ether 8.00±3.19 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2,2',6,6'-tetrachlorobisphenol a 4.86±3.13 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2,2'4,4'-tetrabromodiphenyl ether 22.56±5.18 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane 8.78±1.43 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2,2-bis[(benzoyloxy)methyl]dibenzoate propanediol 4.32±8.63 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2,2'-dichlorobiphenyl 31.09±12.28 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2,2'-dihydroxy-4,4'-dimethoxybenzophenone 7.75±1.80 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2,2'-dihydroxy-4-methoxybenzophenone 9.89±1.04 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2,2'-methylenebis(4-methyl-6-tert-butylphenol) 1.35±0.26 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2,2'-methylenebis(ethyl-6-tert-butylphenol) 1.22±0.73 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2,3',4,4'-tetrahydroxybenzophenone 7.39±7.14 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2,3,4,5-tetrachlorophenol 4.93±2.04 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2,3,4-trichlorophenol 5.23±1.52 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2,3,5,6-tetrachlorophenol 6.42±2.38 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2,3,5-trichlorophenol 5.80±1.05 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2,4,5-trichlorophenol sodium salt 5.05±2.09 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2,4,6-trinitro-1,3-dimethyl-5-tert-butylbenzene 20.09±6.09 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2,4-bis(1-methyl-1-phenylethyl)phenol 3.49±1.51 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2,4-diaminoanisole sulfate 2.51±1.16 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2,4-diaminophenol dihydrochloride 3.77±1.06 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2,4-dichloro-3,5-dimethylphenol 5.88±4.85 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2,4-diisopropylphenol 17.23±1.99 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2,4-di-tert-butylphenol 3.50±0.73 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2,5-bis(2-methylbutan-2-yl)benzene-1,4-diol 6.86±3.17 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2,5-di-tert-butylbenzene-1,4-diol 7.41±1.27 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2,6-bis-(1,1-dimethylethyl)-2,5-cyclohexadiene-1,4-dione 18.60±12.40 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2,6-di(butan-2-yl)phenol 13.69±3.19 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2,6-diaminopyridine 31.28±10.35 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2,6-di-tert-butyl-4-nitrophenol 0.17±0.05 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2,6-toluenediamine 15.70±10.03 human qHTS-HepG2 MMP assay decrease Positive IC50 163
24r,25-dihydroxyvitamin d3 13.02±2.17 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2-Acetylaminofluorene 36.27±10.50 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2-amino-4-(p-nitrophenyl)thiazole 3.90±1.78 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2-amino-4,6-dinitrophenol 4.18±2.00 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2-amino-4-chloro-5-nitrophenol 21.51±2.48 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2-amino-4-chlorobenzothiazole 29.57±5.09 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2-amino-5-nitrophenol 27.40±14.08 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2-amino-6-nitrobenzothiazole 12.69±10.45 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2-aminoanthracene 4.71±1.92 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2-aminoanthraquinone 0.51±0.29 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2-chloro-4-phenylphenol 15.36±7.86 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2-dodecylisoquinolinium tosylate 3.53±0.50 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2-hydrazino-4-(4-aminophenyl) thiazole 0.06±0.02 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2-hydrazino-4-(4-nitrophenyl)thiazole 1.60±0.29 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2-hydrazino-4-phenylthiazole 2.32±0.79 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2-hydroxyanthraquinone 3.31±1.38 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2-isovaleryl-1,3-indanedione 5.24±0.90 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2-methyl-1-nitroanthraquinone 1.34±0.15 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2-methylanthraquinone 6.33±1.15 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2-naphthalenesulfonic acid, 7-amino-4-hydroxy- 27.33±3.73 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2-naphthalenol 50.10±16.03 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2-nitro-1,4-phenylenediamine 7.07±6.53 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2-nitrofluorene 12.19±0.86 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2-pentylfuran 42.19±2.81 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2-phenylphenol 17.90±1.41 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2-propenal,3,3-diphenyl- 41.19±19.34 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2-tert-butyl-4-ethylphenol 11.30±2.60 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2-tert-butyl-4-methoxyphenol 25.29±1.71 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2-tert-butyl-5-methylphenol 23.48±2.85 human qHTS-HepG2 MMP assay decrease Positive IC50 163
3-(5,5,6-trimethylbicyclo[2.2.1]hept-2-yl)cyclohexanol 31.84±17.54 human qHTS-HepG2 MMP assay decrease Positive IC50 163
3,3',4,4'-tetraaminobiphenyl tetrahydrochloride 0.34±0.26 human qHTS-HepG2 MMP assay decrease Positive IC50 163
3,3',5,5'-tetraiodothyroacetic acid 45.79±2.99 human qHTS-HepG2 MMP assay decrease Positive IC50 163
3,3'-diaminobenzidine 13.69±14.86 human qHTS-HepG2 MMP assay decrease Positive IC50 163
3,3'-dimethylbisphenol a 8.88±3.37 human qHTS-HepG2 MMP assay decrease Positive IC50 163
3,3φ,5,5φ-tetrabromobisphenol a 13.23±12.24 human qHTS-HepG2 MMP assay decrease Positive IC50 163
3,4,5-trichlorophenol 3.80±1.74 human qHTS-HepG2 MMP assay decrease Positive IC50 163
3,4-dichlorophenol 9.18±2.63 human qHTS-HepG2 MMP assay decrease Positive IC50 163
3,5-dichlorophenol 9.79±0.00 human qHTS-HepG2 MMP assay decrease Positive IC50 163
3,5-dichlorosalicyl-3,4-dichloroanilide 0.22±0.09 human qHTS-HepG2 MMP assay decrease Positive IC50 163
3-acetylphenanthrene 36.89±13.68 human qHTS-HepG2 MMP assay decrease Positive IC50 163
3-amino-9-ethylcarbazole hydrochloride 35.36±24.49 human qHTS-HepG2 MMP assay decrease Positive IC50 163
3-hydroxybenzophenone 27.72±0.00 human qHTS-HepG2 MMP assay decrease Positive IC50 163
3-hydroxy-n-(3-nitrophenyl)naphthalene-2-carboxamide 0.24±0.09 human qHTS-HepG2 MMP assay decrease Positive IC50 163
3-hydroxy-n-phenylaniline 28.48±6.04 human qHTS-HepG2 MMP assay decrease Positive IC50 163
3-methylbenzene-1,2-diamine 21.74±3.65 human qHTS-HepG2 MMP assay decrease Positive IC50 163
3-methylcholanthrene 17.26±13.23 human qHTS-HepG2 MMP assay decrease Positive IC50 163
3-methyl-n-phenylaniline 48.56±5.61 human qHTS-HepG2 MMP assay decrease Positive IC50 163
4-(1,1,3,3-tetramethylbutyl)phenol 4.25±0.92 human qHTS-HepG2 MMP assay decrease Positive IC50 163
4-(2-methylbutan-2-yl)phenol 22.71±3.07 human qHTS-HepG2 MMP assay decrease Positive IC50 163
4-(3-phenylpropyl)pyridine 16.58±6.74 human qHTS-HepG2 MMP assay decrease Positive IC50 163
4-(benzyloxyl)phenol 18.46±1.51 human qHTS-HepG2 MMP assay decrease Positive IC50 163
4-(butan-2-yl)phenol 31.98±3.64 human qHTS-HepG2 MMP assay decrease Positive IC50 163
4,4,4-trifluoro-1-phenyl-1,3-butanedione 20.37±6.17 human qHTS-HepG2 MMP assay decrease Positive IC50 163
4,4'-diaminoazobenzene 10.45±3.59 human qHTS-HepG2 MMP assay decrease Positive IC50 163
4,4'-diaminobenzanilide 3.72±2.85 human qHTS-HepG2 MMP assay decrease Positive IC50 163
4,4'-dichlorodiphenyl sulfone 21.27±6.06 human qHTS-HepG2 MMP assay decrease Positive IC50 163
4,4'-dinitrodiphenylurea 0.46±0.06 human qHTS-HepG2 MMP assay decrease Positive IC50 163
4,4'-methylenebis(2-chloroaniline) 49.14±17.00 human qHTS-HepG2 MMP assay decrease Positive IC50 163
4,4'-sulfonylbis[2-(prop-2-en-1-yl)phenol] 44.97±17.92 human qHTS-HepG2 MMP assay decrease Positive IC50 163
4,4'-thiobis(6-tert-butyl-m-cresol) 1.86±1.18 human qHTS-HepG2 MMP assay decrease Positive IC50 163
4,4'-thiodiphenol 21.08±2.70 human qHTS-HepG2 MMP assay decrease Positive IC50 163
4,6-dichloro-1,3-benzenediol 9.55±2.74 human qHTS-HepG2 MMP assay decrease Positive IC50 163
4,6-di-tert-butyl-m-cresol 2.25±1.49 human qHTS-HepG2 MMP assay decrease Positive IC50 163
4-amino-2,6-dichlorophenol 17.23±13.38 human qHTS-HepG2 MMP assay decrease Positive IC50 163
4-amino-2-nitrophenol 15.42±10.56 human qHTS-HepG2 MMP assay decrease Positive IC50 163
4-amino-4φ-hydroxy-3-methyldiphenylamine 7.66±0.88 human qHTS-HepG2 MMP assay decrease Positive IC50 163
4-benzylphenol 15.94±3.38 human qHTS-HepG2 MMP assay decrease Positive IC50 163
4-chloro-1,2-diaminobenzene 2.38±1.60 human qHTS-HepG2 MMP assay decrease Positive IC50 163
4-chloro-2-cyclopentylphenol 5.66±1.93 human qHTS-HepG2 MMP assay decrease Positive IC50 163
4-chloro-3,5-dimethylphenol 21.00±0.00 human qHTS-HepG2 MMP assay decrease Positive IC50 163
4-chlorophenyl isocyanate 0.27±0.11 human qHTS-HepG2 MMP assay decrease Positive IC50 163
4-cumylphenol 3.70±0.82 human qHTS-HepG2 MMP assay decrease Positive IC50 163
4'-demethylepipodophyllotoxin 2.66±3.92 human qHTS-HepG2 MMP assay decrease Positive IC50 163
4-dodecylphenol 3.18±0.58 human qHTS-HepG2 MMP assay decrease Positive IC50 163
4-hexyl-4'-cyanobiphenyl 42.53±15.42 human qHTS-HepG2 MMP assay decrease Positive IC50 163
4-hydroxybenzophenone 41.31±18.12 human qHTS-HepG2 MMP assay decrease Positive IC50 163
4-methyl-2,6-dinitrophenol 26.55±4.57 human qHTS-HepG2 MMP assay decrease Positive IC50 163
4-nitroanthranilic acid 38.57±17.22 human qHTS-HepG2 MMP assay decrease Positive IC50 163
4-nitro-n-phenylaniline 7.43±6.54 human qHTS-HepG2 MMP assay decrease Positive IC50 163
4-nitrosophenol 4.71±2.31 human qHTS-HepG2 MMP assay decrease Positive IC50 163
4-octyloxybenzoic acid 39.63±31.34 human qHTS-HepG2 MMP assay decrease Positive IC50 163
4-octylphenol 8.77±2.96 human qHTS-HepG2 MMP assay decrease Positive IC50 163
4-phenoxyphenol 27.97±10.62 human qHTS-HepG2 MMP assay decrease Positive IC50 163
4-styrylpyridine 11.22±5.54 human qHTS-HepG2 MMP assay decrease Positive IC50 163
4-tert-butylcatechol 34.27±14.96 human qHTS-HepG2 MMP assay decrease Positive IC50 163
4-tert-butylphenyl salicylate 28.37±3.64 human qHTS-HepG2 MMP assay decrease Positive IC50 163
5,7-dichloro-8-hydroxy-2-methylquinoline 11.01±2.00 human qHTS-HepG2 MMP assay decrease Positive IC50 163
5alpha-dihydrotestosterone 13.30±6.16 human qHTS-HepG2 MMP assay decrease Positive IC50 163
5hpp-33 2.09±0.87 human qHTS-HepG2 MMP assay decrease Positive IC50 163
Busulfan 14.43±5.99 human qHTS-HepG2 MMP assay decrease Positive IC50 163
5-nitroacenaphthene 34.38±20.44 human qHTS-HepG2 MMP assay decrease Positive IC50 163
6-hydroxy-2-naphthyl disulfide 33.74±3.64 human qHTS-HepG2 MMP assay decrease Positive IC50 163
6-nitrobenzimidazole 36.41±10.82 human qHTS-HepG2 MMP assay decrease Positive IC50 163
6-nitroquinoline 30.73±11.46 human qHTS-HepG2 MMP assay decrease Positive IC50 163
9,10-dihydrobenzo[a]pyren-7(8h)-one 9.81±2.08 human qHTS-HepG2 MMP assay decrease Positive IC50 163
9-aminoacridine, monohydrochloride, monohydrate 13.80±1.75 human qHTS-HepG2 MMP assay decrease Positive IC50 163
9-anthracenemethanol 34.48±11.46 human qHTS-HepG2 MMP assay decrease Positive IC50 163
9-cyanoanthracene 6.85±18.05 human qHTS-HepG2 MMP assay decrease Positive IC50 163
9-nitroanthracene 21.44±12.82 human qHTS-HepG2 MMP assay decrease Positive IC50 163
9-phenanthrol 1.22±0.56 human qHTS-HepG2 MMP assay decrease Positive IC50 163
acenocoumarol 8.36±1.07 human qHTS-HepG2 MMP assay decrease Positive IC50 163
acetaldehyde 18.02±6.38 human qHTS-HepG2 MMP assay decrease Positive IC50 163
aclarubicin hydrochloride 3.15±2.82 human qHTS-HepG2 MMP assay decrease Positive IC50 163
acriflavine hydrochloride 0.94±0.44 human qHTS-HepG2 MMP assay decrease Positive IC50 163
Albendazole 9.35±1.83 human qHTS-HepG2 MMP assay decrease Positive IC50 163
aldrin 31.20±7.21 human qHTS-HepG2 MMP assay decrease Positive IC50 163
alizarin 11.01±1.41 human qHTS-HepG2 MMP assay decrease Positive IC50 163
allylestrenol 12.83±3.68 human qHTS-HepG2 MMP assay decrease Positive IC50 163
aloe-emodin 1.79±1.54 human qHTS-HepG2 MMP assay decrease Positive IC50 163
alpha-1,2,3,4,5,6-hexachlorocyclohexane 49.00±6.35 human qHTS-HepG2 MMP assay decrease Positive IC50 163
alpha-amylcinnamyl alcohol 38.11±17.40 human qHTS-HepG2 MMP assay decrease Positive IC50 163
ambazone 5.60±3.23 human qHTS-HepG2 MMP assay decrease Positive IC50 163
ami-193 5.82±3.05 human qHTS-HepG2 MMP assay decrease Positive IC50 163
aminoquinuride dihydrochloride 25.01±4.09 human qHTS-HepG2 MMP assay decrease Positive IC50 163
amorolfine 21.61±3.47 human qHTS-HepG2 MMP assay decrease Positive IC50 163
amsacrine hydrochloride 10.34±2.45 human qHTS-HepG2 MMP assay decrease Positive IC50 163
amylmetacresol 11.17±0.65 human qHTS-HepG2 MMP assay decrease Positive IC50 163
anthrone 21.84±9.90 human qHTS-HepG2 MMP assay decrease Positive IC50 163
apigenin 1.61±0.00 human qHTS-HepG2 MMP assay decrease Positive IC50 163
aranidipine 12.83±3.68 human qHTS-HepG2 MMP assay decrease Positive IC50 163
aroclor 1260 21.47±2.75 human qHTS-HepG2 MMP assay decrease Positive IC50 163
arotinolol hydrochloride 17.04±3.45 human qHTS-HepG2 MMP assay decrease Positive IC50 163
axitinib 3.76±2.80 human qHTS-HepG2 MMP assay decrease Positive IC50 163
barban 22.54±4.10 human qHTS-HepG2 MMP assay decrease Positive IC50 163
bardoxolone methyl 5.11±1.27 human qHTS-HepG2 MMP assay decrease Positive IC50 163
barium bis(2-ethylhexanoate) 15.36±10.31 human qHTS-HepG2 MMP assay decrease Positive IC50 163
barium chloride 16.58±8.50 human qHTS-HepG2 MMP assay decrease Positive IC50 163
basic blue 7 0.02±0.03 human qHTS-HepG2 MMP assay decrease Positive IC50 163
bazedoxifene 11.01±0.75 human qHTS-HepG2 MMP assay decrease Positive IC50 163
beclazone 23.71±2.74 human qHTS-HepG2 MMP assay decrease Positive IC50 163
benzbromarone 7.22±1.24 human qHTS-HepG2 MMP assay decrease Positive IC50 163
benzidine 24.34±4.50 human qHTS-HepG2 MMP assay decrease Positive IC50 163
benziodarone 2.98±0.63 human qHTS-HepG2 MMP assay decrease Positive IC50 163
benzobarbital 24.07±5.12 human qHTS-HepG2 MMP assay decrease Positive IC50 163
benzoic acid, 2-[(4-chloro-3-methylphenyl)amino]- 12.83±0.84 human qHTS-HepG2 MMP assay decrease Positive IC50 163
benzyldimethyltetradecylammonium chloride dihydrate 16.40±4.28 human qHTS-HepG2 MMP assay decrease Positive IC50 163
benzyldodecyldimethylammonium bromide 11.44±4.34 human qHTS-HepG2 MMP assay decrease Positive IC50 163
benzylhydrazine dihydrochloride 27.81±3.21 human qHTS-HepG2 MMP assay decrease Positive IC50 163
berberine chloride 2.03±1.29 human qHTS-HepG2 MMP assay decrease Positive IC50 163
betamethasone dipropionate 25.60±1.67 human qHTS-HepG2 MMP assay decrease Positive IC50 163
bexarotene 16.49±3.95 human qHTS-HepG2 MMP assay decrease Positive IC50 163
bis(tributyltin)oxide 0.09±0.02 human qHTS-HepG2 MMP assay decrease Positive IC50 163
bisacodyl 14.82±3.63 human qHTS-HepG2 MMP assay decrease Positive IC50 163
Bisphenol A 13.97±6.29 human qHTS-HepG2 MMP assay decrease Positive IC50 163
bisphenol a glycidyl methacrylate 12.20±11.86 human qHTS-HepG2 MMP assay decrease Positive IC50 163
bisphenol af 5.44±1.42 human qHTS-HepG2 MMP assay decrease Positive IC50 163
bisphenol b 10.66±2.48 human qHTS-HepG2 MMP assay decrease Positive IC50 163
bisphenol e 27.64±1.80 human qHTS-HepG2 MMP assay decrease Positive IC50 163
bisphenol z 22.19±5.51 human qHTS-HepG2 MMP assay decrease Positive IC50 163
bithionol 0.66±0.52 human qHTS-HepG2 MMP assay decrease Positive IC50 163
bosutinib 0.75±0.48 human qHTS-HepG2 MMP assay decrease Positive IC50 163
bromadiolone 16.67±1.13 human qHTS-HepG2 MMP assay decrease Positive IC50 163
bromociclen 33.18±3.47 human qHTS-HepG2 MMP assay decrease Positive IC50 163
bromocriptine 11.44±1.58 human qHTS-HepG2 MMP assay decrease Positive IC50 163
bromocriptine mesylate 11.19±2.78 human qHTS-HepG2 MMP assay decrease Positive IC50 163
bromofenoxim 1.08±0.25 human qHTS-HepG2 MMP assay decrease Positive IC50 163
bromofos 7.70±1.63 human qHTS-HepG2 MMP assay decrease Positive IC50 163
bromoxynil octanoate 15.29±5.08 human qHTS-HepG2 MMP assay decrease Positive IC50 163
broquinaldol 26.60±4.00 human qHTS-HepG2 MMP assay decrease Positive IC50 163
bryostatin 1 0.01±0.01 human qHTS-HepG2 MMP assay decrease Positive IC50 163
buclizine dihydrochloride 32.23±2.10 human qHTS-HepG2 MMP assay decrease Positive IC50 163
butylparaben 19.00±0.00 human qHTS-HepG2 MMP assay decrease Positive IC50 163
c.i. 1040 8.10±1.39 human qHTS-HepG2 MMP assay decrease Positive IC50 163
c.i. basic orange 2 7.53±5.61 human qHTS-HepG2 MMP assay decrease Positive IC50 163
c.i. basic red 9 monohydrochloride 0.08±0.02 human qHTS-HepG2 MMP assay decrease Positive IC50 163
c.i. basic violet 14 0.18±0.16 human qHTS-HepG2 MMP assay decrease Positive IC50 163
c.i. disperse blue 27 2.34±0.87 human qHTS-HepG2 MMP assay decrease Positive IC50 163
c.i. solvent yellow 14 5.84±2.06 human qHTS-HepG2 MMP assay decrease Positive IC50 163
calcifediol 5.82±0.47 human qHTS-HepG2 MMP assay decrease Positive IC50 163
calcipotriene 25.98±3.89 human qHTS-HepG2 MMP assay decrease Positive IC50 163
calcitriol 14.06±4.15 human qHTS-HepG2 MMP assay decrease Positive IC50 163
candesartan cilexetil 15.94±4.62 human qHTS-HepG2 MMP assay decrease Positive IC50 163
cannabinol 1.68±0.00 human qHTS-HepG2 MMP assay decrease Positive IC50 163
cantharidin 0.15±0.08 human qHTS-HepG2 MMP assay decrease Positive IC50 163
CCCP 0.15±0.04 human qHTS-HepG2 MMP assay decrease Positive IC50 163
carminomycin 1.25±0.73 human qHTS-HepG2 MMP assay decrease Positive IC50 163
chlorfenapyr 0.07±0.04 human qHTS-HepG2 MMP assay decrease Positive IC50 163
chlorfenethol 26.28±7.53 human qHTS-HepG2 MMP assay decrease Positive IC50 163
chlorfenson 38.83±25.41 human qHTS-HepG2 MMP assay decrease Positive IC50 163
chlorfluazuron 8.93±4.57 human qHTS-HepG2 MMP assay decrease Positive IC50 163
chlorophacinone 0.64±0.25 human qHTS-HepG2 MMP assay decrease Positive IC50 163
chloropropylate 26.28±3.64 human qHTS-HepG2 MMP assay decrease Positive IC50 163
chloroxine 10.59±1.22 human qHTS-HepG2 MMP assay decrease Positive IC50 163
chromomycin 12.35±0.84 human qHTS-HepG2 MMP assay decrease Positive IC50 163
chrysarobin 22.82±3.93 human qHTS-HepG2 MMP assay decrease Positive IC50 163
chrysin 5.05±2.76 human qHTS-HepG2 MMP assay decrease Positive IC50 163
ciclesonide 7.91±1.38 human qHTS-HepG2 MMP assay decrease Positive IC50 163
Ciglitazone 8.22±1.60 human qHTS-HepG2 MMP assay decrease Positive IC50 163
cilnidipine 12.53±1.78 human qHTS-HepG2 MMP assay decrease Positive IC50 163
cinalukast 28.81±1.17 human qHTS-HepG2 MMP assay decrease Positive IC50 163
clobetasol 14.40±3.67 human qHTS-HepG2 MMP assay decrease Positive IC50 163
clobetasol propionate 24.64±1.67 human qHTS-HepG2 MMP assay decrease Positive IC50 163
cloflucarban 0.60±0.00 human qHTS-HepG2 MMP assay decrease Positive IC50 163
clofoctol 1.64±0.13 human qHTS-HepG2 MMP assay decrease Positive IC50 163
clonixin 19.86±6.75 human qHTS-HepG2 MMP assay decrease Positive IC50 163
cloxyquin 16.79±5.94 human qHTS-HepG2 MMP assay decrease Positive IC50 163
coumatetralyl 13.69±4.84 human qHTS-HepG2 MMP assay decrease Positive IC50 163
cresyl diphenyl phosphate 2.38±2.32 human qHTS-HepG2 MMP assay decrease Positive IC50 163
curcumin 1.31±1.03 human qHTS-HepG2 MMP assay decrease Positive IC50 163
cybutryne 20.87±13.91 human qHTS-HepG2 MMP assay decrease Positive IC50 163
cyclododecanol 48.78±3.84 human qHTS-HepG2 MMP assay decrease Positive IC50 163
cyhalothrin 33.62±5.79 human qHTS-HepG2 MMP assay decrease Positive IC50 163
d&c yellow 11 0.38±0.13 human qHTS-HepG2 MMP assay decrease Positive IC50 163
danthron 4.66±1.19 human qHTS-HepG2 MMP assay decrease Positive IC50 163
dantrolene sodium 4.35±1.73 human qHTS-HepG2 MMP assay decrease Positive IC50 163
darbufelone mesylate 11.74±2.02 human qHTS-HepG2 MMP assay decrease Positive IC50 163
deltamethrin 45.88±17.92 human qHTS-HepG2 MMP assay decrease Positive IC50 163
deslanoside 1.84±0.23 human qHTS-HepG2 MMP assay decrease Positive IC50 163
desogestrel 22.29±2.11 human qHTS-HepG2 MMP assay decrease Positive IC50 163
devazepide 12.53±5.62 human qHTS-HepG2 MMP assay decrease Positive IC50 163
dexamethasone valerate 12.06±4.39 human qHTS-HepG2 MMP assay decrease Positive IC50 163
diacerein 20.64±8.26 human qHTS-HepG2 MMP assay decrease Positive IC50 163
dianiline 18.40±5.73 human qHTS-HepG2 MMP assay decrease Positive IC50 163
dichlofluanid 5.24±1.99 human qHTS-HepG2 MMP assay decrease Positive IC50 163
dichlorodiphenylsilane 12.96±9.66 human qHTS-HepG2 MMP assay decrease Positive IC50 163
diclazuril 11.17±2.79 human qHTS-HepG2 MMP assay decrease Positive IC50 163
dicofol 9.69±3.51 human qHTS-HepG2 MMP assay decrease Positive IC50 163
N,N'-dicyclohexylcarbodiimide 0.30±0.20 human qHTS-HepG2 MMP assay decrease Positive IC50 163
dienestrol 10.93±1.88 human qHTS-HepG2 MMP assay decrease Positive IC50 163
Diethylstilbestrol 9.76±6.25 human qHTS-HepG2 MMP assay decrease Positive IC50 163
diethylstilbestrol dipropionate 10.46±2.66 human qHTS-HepG2 MMP assay decrease Positive IC50 163
diflorasone diacetate 28.73±1.87 human qHTS-HepG2 MMP assay decrease Positive IC50 163
digitoxin 0.16±0.05 human qHTS-HepG2 MMP assay decrease Positive IC50 163
digoxin 0.52±0.09 human qHTS-HepG2 MMP assay decrease Positive IC50 163
dihydrotachysterol 32.71±1.32 human qHTS-HepG2 MMP assay decrease Positive IC50 163
dinex 0.28±0.34 human qHTS-HepG2 MMP assay decrease Positive IC50 163
diniconazole 12.18±3.53 human qHTS-HepG2 MMP assay decrease Positive IC50 163
dinobuton 4.33±1.24 human qHTS-HepG2 MMP assay decrease Positive IC50 163
dinocap 0.34±0.30 human qHTS-HepG2 MMP assay decrease Positive IC50 163
dinoterb 0.48±0.00 human qHTS-HepG2 MMP assay decrease Positive IC50 163
diphenan 22.29±4.67 human qHTS-HepG2 MMP assay decrease Positive IC50 163
diphenoxylate hydrochloride 20.65±1.19 human qHTS-HepG2 MMP assay decrease Positive IC50 163
diphenylcyclopropenone 25.60±1.67 human qHTS-HepG2 MMP assay decrease Positive IC50 163
diphenylurea 1.60±0.74 human qHTS-HepG2 MMP assay decrease Positive IC50 163
disperse red 82 8.00±1.45 human qHTS-HepG2 MMP assay decrease Positive IC50 163
dithiazanine chloride 0.27±0.82 human qHTS-HepG2 MMP assay decrease Positive IC50 163
dithiazanine iodide 0.10±0.15 human qHTS-HepG2 MMP assay decrease Positive IC50 163
docetaxel 14.96±29.77 human qHTS-HepG2 MMP assay decrease Positive IC50 163
dodecyl gallate 4.75±1.81 human qHTS-HepG2 MMP assay decrease Positive IC50 163
dodecylparaben 4.19±1.07 human qHTS-HepG2 MMP assay decrease Positive IC50 163
dodecylphenol 3.10±1.22 human qHTS-HepG2 MMP assay decrease Positive IC50 163
doramapimod;bibr-796? 21.13±5.52 human qHTS-HepG2 MMP assay decrease Positive IC50 163
doramectin 11.88±0.00 human qHTS-HepG2 MMP assay decrease Positive IC50 163
ebselen 23.16±0.93 human qHTS-HepG2 MMP assay decrease Positive IC50 163
emodin 1.33±0.78 human qHTS-HepG2 MMP assay decrease Positive IC50 163
endosulfan sulfate 15.96±2.05 human qHTS-HepG2 MMP assay decrease Positive IC50 163
endrin 23.52±7.96 human qHTS-HepG2 MMP assay decrease Positive IC50 163
enterolactone 9.99±5.02 human qHTS-HepG2 MMP assay decrease Positive IC50 163
eprinomectin (b1a, b1b mixture) 4.22±0.90 human qHTS-HepG2 MMP assay decrease Positive IC50 163
equilin 24.34±4.60 human qHTS-HepG2 MMP assay decrease Positive IC50 163
ergotamine d-tartrate 7.55±1.06 human qHTS-HepG2 MMP assay decrease Positive IC50 163
estradiol acetate 9.08±0.59 human qHTS-HepG2 MMP assay decrease Positive IC50 163
ethacridine lactate hydrate 3.22±0.55 human qHTS-HepG2 MMP assay decrease Positive IC50 163
ethalfluralin 43.28±17.60 human qHTS-HepG2 MMP assay decrease Positive IC50 163
ethanol, 2,2'-((1-methylethylidene)bis((2,6-dibromo-4,1-phenylene)oxy))bis- 6.21±0.42 human qHTS-HepG2 MMP assay decrease Positive IC50 163
ethoxazene 2.70±1.13 human qHTS-HepG2 MMP assay decrease Positive IC50 163
ethyl linolenate 49.65±36.02 human qHTS-HepG2 MMP assay decrease Positive IC50 163
ethynodiol diacetate 15.40±0.84 human qHTS-HepG2 MMP assay decrease Positive IC50 163
etocarlide 17.04±6.52 human qHTS-HepG2 MMP assay decrease Positive IC50 163
everolimus 19.86±2.83 human qHTS-HepG2 MMP assay decrease Positive IC50 163
exalamide 9.81±3.00 human qHTS-HepG2 MMP assay decrease Positive IC50 163
ezetimibe 25.60±3.54 human qHTS-HepG2 MMP assay decrease Positive IC50 163
famoxadone 4.19±1.07 human qHTS-HepG2 MMP assay decrease Positive IC50 163
fenamidone 43.28±17.10 human qHTS-HepG2 MMP assay decrease Positive IC50 163
fenarimol 42.59±21.91 human qHTS-HepG2 MMP assay decrease Positive IC50 163
fenchlorphos 13.62±2.52 human qHTS-HepG2 MMP assay decrease Positive IC50 163
fendiline hydrochloride 10.34±1.55 human qHTS-HepG2 MMP assay decrease Positive IC50 163
fenhexamid 8.31±1.15 human qHTS-HepG2 MMP assay decrease Positive IC50 163
fenobam 25.85±1.87 human qHTS-HepG2 MMP assay decrease Positive IC50 163
fenretinide 3.40±0.76 human qHTS-HepG2 MMP assay decrease Positive IC50 163
fentiazac 27.43±2.92 human qHTS-HepG2 MMP assay decrease Positive IC50 163
fenticlor 2.15±0.36 human qHTS-HepG2 MMP assay decrease Positive IC50 163
fenvalerate 32.06±0.00 human qHTS-HepG2 MMP assay decrease Positive IC50 163
flopropione 18.83±6.83 human qHTS-HepG2 MMP assay decrease Positive IC50 163
fluazuron 3.96±2.31 human qHTS-HepG2 MMP assay decrease Positive IC50 163
flubendiamide 18.72±2.59 human qHTS-HepG2 MMP assay decrease Positive IC50 163
flucythrinate 35.72±20.02 human qHTS-HepG2 MMP assay decrease Positive IC50 163
Flufenamic Acid 36.64±1.87 human qHTS-HepG2 MMP assay decrease Positive IC50 163
flunixin meglumine 9.02±0.00 human qHTS-HepG2 MMP assay decrease Positive IC50 163
fluorodifen 27.31±25.06 human qHTS-HepG2 MMP assay decrease Positive IC50 163
fluorosalan 0.24±0.09 human qHTS-HepG2 MMP assay decrease Positive IC50 163
fluoxastrobin 45.79±15.00 human qHTS-HepG2 MMP assay decrease Positive IC50 163
fluticasone propionate 9.02±1.71 human qHTS-HepG2 MMP assay decrease Positive IC50 163
fluvastatin 27.64±1.87 human qHTS-HepG2 MMP assay decrease Positive IC50 163
folpet 8.25±0.54 human qHTS-HepG2 MMP assay decrease Positive IC50 163
forchlorfenuron 0.45±0.13 human qHTS-HepG2 MMP assay decrease Positive IC50 163
formononetin 13.17±4.88 human qHTS-HepG2 MMP assay decrease Positive IC50 163
fulvestrant 5.86±0.82 human qHTS-HepG2 MMP assay decrease Positive IC50 163
geliomycin 0.52±0.04 human qHTS-HepG2 MMP assay decrease Positive IC50 163
genistein 6.34±0.77 human qHTS-HepG2 MMP assay decrease Positive IC50 163
gentian violet 0.08±0.04 human qHTS-HepG2 MMP assay decrease Positive IC50 163
glycyrrhetinic acid 40.10±9.34 human qHTS-HepG2 MMP assay decrease Positive IC50 163
gramicidin 0.51±0.42 human qHTS-HepG2 MMP assay decrease Positive IC50 163
halobetasol propionate 15.18±5.52 human qHTS-HepG2 MMP assay decrease Positive IC50 163
heptachlor 39.40±17.92 human qHTS-HepG2 MMP assay decrease Positive IC50 163
Hexachlorophene 0.70±0.46 human qHTS-HepG2 MMP assay decrease Positive IC50 163
hydroxystilbamidine bis(methanesulfonate) 2.81±0.90 human qHTS-HepG2 MMP assay decrease Positive IC50 163
idarubicin hydrochloride 6.83±1.46 human qHTS-HepG2 MMP assay decrease Positive IC50 163
idazoxan 20.64±7.46 human qHTS-HepG2 MMP assay decrease Positive IC50 163
indole-3-pyruvic acid 28.92±16.69 human qHTS-HepG2 MMP assay decrease Positive IC50 163
indoxacarb 12.73±3.65 human qHTS-HepG2 MMP assay decrease Positive IC50 163
iodophthalein 5.31±1.76 human qHTS-HepG2 MMP assay decrease Positive IC50 163
iodophthalein sodium 10.75±3.91 human qHTS-HepG2 MMP assay decrease Positive IC50 163
isobutylparaben 14.21±1.82 human qHTS-HepG2 MMP assay decrease Positive IC50 163
isodrin 43.28±15.32 human qHTS-HepG2 MMP assay decrease Positive IC50 163
isoxaben 26.32±5.75 human qHTS-HepG2 MMP assay decrease Positive IC50 163
isoxicam 5.18±2.90 human qHTS-HepG2 MMP assay decrease Positive IC50 163
israpafant 21.96±1.49 human qHTS-HepG2 MMP assay decrease Positive IC50 163
kaempferol 2.56±3.04 human qHTS-HepG2 MMP assay decrease Positive IC50 163
kepone 0.93±0.65 human qHTS-HepG2 MMP assay decrease Positive IC50 163
Ketoconazole 10.81±3.25 human qHTS-HepG2 MMP assay decrease Positive IC50 163
lambda-cyhalothrin 24.35±1.59 human qHTS-HepG2 MMP assay decrease Positive IC50 163
lanatoside a 0.43±0.04 human qHTS-HepG2 MMP assay decrease Positive IC50 163
lanatoside b 1.10±0.20 human qHTS-HepG2 MMP assay decrease Positive IC50 163
lanatoside c 0.78±0.14 human qHTS-HepG2 MMP assay decrease Positive IC50 163
lapachol 26.12±1.70 human qHTS-HepG2 MMP assay decrease Positive IC50 163
lasalocid sodium 1.14±0.07 human qHTS-HepG2 MMP assay decrease Positive IC50 163
lercanidipine hydrochloride 6.53±0.53 human qHTS-HepG2 MMP assay decrease Positive IC50 163
lestaurtinib 4.80±0.97 human qHTS-HepG2 MMP assay decrease Positive IC50 163
lopinavir 32.71±1.32 human qHTS-HepG2 MMP assay decrease Positive IC50 163
lornoxicam 9.44±1.09 human qHTS-HepG2 MMP assay decrease Positive IC50 163
lufenuron 7.65±0.70 human qHTS-HepG2 MMP assay decrease Positive IC50 163
lynestrenol 16.63±2.15 human qHTS-HepG2 MMP assay decrease Positive IC50 163
lysergide 9.03±1.87 human qHTS-HepG2 MMP assay decrease Positive IC50 163
malachite green oxalate 2.10±1.87 human qHTS-HepG2 MMP assay decrease Positive IC50 163
malotilate 14.96±1.99 human qHTS-HepG2 MMP assay decrease Positive IC50 163
manidipine 12.15±6.82 human qHTS-HepG2 MMP assay decrease Positive IC50 163
Mebendazole 2.45±0.34 human qHTS-HepG2 MMP assay decrease Positive IC50 163
Meloxicam 14.47±0.00 human qHTS-HepG2 MMP assay decrease Positive IC50 163
mepartricin 23.16±6.59 human qHTS-HepG2 MMP assay decrease Positive IC50 163
mepronil 40.86±19.18 human qHTS-HepG2 MMP assay decrease Positive IC50 163
mesotrione 17.97±11.96 human qHTS-HepG2 MMP assay decrease Positive IC50 163
metanixin 25.98±2.11 human qHTS-HepG2 MMP assay decrease Positive IC50 163
methfuroxam 25.78±1.71 human qHTS-HepG2 MMP assay decrease Positive IC50 163
methisazone 5.82±1.38 human qHTS-HepG2 MMP assay decrease Positive IC50 163
Methoxychlor 26.28±8.69 human qHTS-HepG2 MMP assay decrease Positive IC50 163
methyl 2,4-dihydroxy-3,6-dimethylbenzoate 15.96±6.62 human qHTS-HepG2 MMP assay decrease Positive IC50 163
methyl triclosan 25.53±1.67 human qHTS-HepG2 MMP assay decrease Positive IC50 163
methyl violet 0.07±0.03 human qHTS-HepG2 MMP assay decrease Positive IC50 163
methyldigoxin 0.73±0.09 human qHTS-HepG2 MMP assay decrease Positive IC50 163
Methylene Blue 2.88±1.33 human qHTS-HepG2 MMP assay decrease Positive IC50 163
methylene blue trihydrate 1.31±0.79 human qHTS-HepG2 MMP assay decrease Positive IC50 163
methylsilanetriyl triacetate 29.07±16.38 human qHTS-HepG2 MMP assay decrease Positive IC50 163
methyltrioctylammonium trifluoromethanesulfonate 2.16±0.72 human qHTS-HepG2 MMP assay decrease Positive IC50 163
metochalcone 18.18±10.11 human qHTS-HepG2 MMP assay decrease Positive IC50 163
mgk-264 15.36±10.52 human qHTS-HepG2 MMP assay decrease Positive IC50 163
mifepristone 16.13±32.54 human qHTS-HepG2 MMP assay decrease Positive IC50 163
miripirium chloride 16.40±4.01 human qHTS-HepG2 MMP assay decrease Positive IC50 163
mk-2206 17.78±7.38 human qHTS-HepG2 MMP assay decrease Positive IC50 163
mometasone furoate 11.80±0.80 human qHTS-HepG2 MMP assay decrease Positive IC50 163
montelukast sodium 32.71±1.32 human qHTS-HepG2 MMP assay decrease Positive IC50 163
n,n-diethylbenzene-1,4-diamine 49.89±3.51 human qHTS-HepG2 MMP assay decrease Positive IC50 163
n,n-dimethyl-p-phenylenediamine 9.10±0.59 human qHTS-HepG2 MMP assay decrease Positive IC50 163
n,nφ-diethylcarbanilide 21.69±38.23 human qHTS-HepG2 MMP assay decrease Positive IC50 163
n-benzyl-6-ethoxy-4-oxo-1,4-dihydro-1,5-naphthyridine-3-carboxamide 14.78±9.66 human qHTS-HepG2 MMP assay decrease Positive IC50 163
n-cyclohexyl-4-methyl benzenesulfonamide 36.15±20.97 human qHTS-HepG2 MMP assay decrease Positive IC50 163
nelfinavir mesylate 11.88±6.92 human qHTS-HepG2 MMP assay decrease Positive IC50 163
Niclosamide 0.03±0.01 human qHTS-HepG2 MMP assay decrease Positive IC50 163
niflumic acid 13.02±2.17 human qHTS-HepG2 MMP assay decrease Positive IC50 163
nifuroxazide 1.57±0.30 human qHTS-HepG2 MMP assay decrease Positive IC50 163
Nimesulide 3.87±0.23 human qHTS-HepG2 MMP assay decrease Positive IC50 163
ninhydrin 32.00±9.69 human qHTS-HepG2 MMP assay decrease Positive IC50 163
Nitazoxanide 1.04±0.96 human qHTS-HepG2 MMP assay decrease Positive IC50 163
Nitrofurantoin 26.31±6.35 human qHTS-HepG2 MMP assay decrease Positive IC50 163
nitrovin 3.27±0.57 human qHTS-HepG2 MMP assay decrease Positive IC50 163
nitroxoline 9.22±2.41 human qHTS-HepG2 MMP assay decrease Positive IC50 163
n-methyl-n,n-dioctyloctan-1-aminium chloride 2.73±0.32 human qHTS-HepG2 MMP assay decrease Positive IC50 163
nocodazole 3.53±1.63 human qHTS-HepG2 MMP assay decrease Positive IC50 163
nonylparaben 4.43±0.30 human qHTS-HepG2 MMP assay decrease Positive IC50 163
norelgestromin 13.53±6.64 human qHTS-HepG2 MMP assay decrease Positive IC50 163
noristerat 9.81±1.78 human qHTS-HepG2 MMP assay decrease Positive IC50 163
n-phenyl-1,4-benzenediamine hydrochloride 5.82±6.96 human qHTS-HepG2 MMP assay decrease Positive IC50 163
o,p'-ddd 19.83±0.94 human qHTS-HepG2 MMP assay decrease Positive IC50 163
o,p'-ddt 23.98±12.11 human qHTS-HepG2 MMP assay decrease Positive IC50 163
olvanil 13.53±1.90 human qHTS-HepG2 MMP assay decrease Positive IC50 163
osalmid 6.68±0.77 human qHTS-HepG2 MMP assay decrease Positive IC50 163
ouabain 0.18±0.00 human qHTS-HepG2 MMP assay decrease Positive IC50 163
oxyphenisatin acetate 5.49±4.60 human qHTS-HepG2 MMP assay decrease Positive IC50 163
p,p'-ddd 15.19±8.82 human qHTS-HepG2 MMP assay decrease Positive IC50 163
p,p'-dde 25.60±1.71 human qHTS-HepG2 MMP assay decrease Positive IC50 163
p,p'-ddt 24.26±2.74 human qHTS-HepG2 MMP assay decrease Positive IC50 163
palmatine chloride hydrate 22.74±5.23 human qHTS-HepG2 MMP assay decrease Positive IC50 163
paricalcitol 8.91±1.56 human qHTS-HepG2 MMP assay decrease Positive IC50 163
p-benzoquinone dioxime 43.30±14.86 human qHTS-HepG2 MMP assay decrease Positive IC50 163
penfluridol 33.49±0.00 human qHTS-HepG2 MMP assay decrease Positive IC50 163
2,2',4,4',5-pentabromodiphenyl ether 15.46±7.01 human qHTS-HepG2 MMP assay decrease Positive IC50 163
pentabromophenol 3.46±0.99 human qHTS-HepG2 MMP assay decrease Positive IC50 163
Pentachlorophenol 3.09±0.60 human qHTS-HepG2 MMP assay decrease Positive IC50 163
pentylparaben 8.74±1.65 human qHTS-HepG2 MMP assay decrease Positive IC50 163
perfluorooctanesulfonamide 2.43±0.81 human qHTS-HepG2 MMP assay decrease Positive IC50 163
phenazopyridine hydrochloride 15.72±3.45 human qHTS-HepG2 MMP assay decrease Positive IC50 163
phenmedipham 4.41±2.02 human qHTS-HepG2 MMP assay decrease Positive IC50 163
phenol, 4,4'-butylidenebis[2-(1,1-dimethylethyl)-5-methyl- 5.51±1.58 human qHTS-HepG2 MMP assay decrease Positive IC50 163
phenol, 4-methyl-, reaction products with dicyclopentadiene and isobutylene 15.55±8.56 human qHTS-HepG2 MMP assay decrease Positive IC50 163
phenolphthalein 42.78±2.74 human qHTS-HepG2 MMP assay decrease Positive IC50 163
phenoxybenzamine hydrochloride 48.80±9.17 human qHTS-HepG2 MMP assay decrease Positive IC50 163
phenyl isothiocyanate 43.01±14.76 human qHTS-HepG2 MMP assay decrease Positive IC50 163
phloretin 4.26±1.22 human qHTS-HepG2 MMP assay decrease Positive IC50 163
picoxystrobin 9.31±2.67 human qHTS-HepG2 MMP assay decrease Positive IC50 163
picropodophyllin 0.14±0.02 human qHTS-HepG2 MMP assay decrease Positive IC50 163
pinacyanol 0.01±0.00 human qHTS-HepG2 MMP assay decrease Positive IC50 163
pirarubicin 0.60±0.46 human qHTS-HepG2 MMP assay decrease Positive IC50 163
pirenoxine sodium 21.13±17.82 human qHTS-HepG2 MMP assay decrease Positive IC50 163
Piroxicam 8.21±1.71 human qHTS-HepG2 MMP assay decrease Positive IC50 163
polyethylene glycol (9z)-9-octadecenyl ether 7.50±18.45 human qHTS-HepG2 MMP assay decrease Positive IC50 163
polyoxyethylene(10)nonylphenyl ether 10.20±6.92 human qHTS-HepG2 MMP assay decrease Positive IC50 163
p-phenylazophenol 4.06±1.23 human qHTS-HepG2 MMP assay decrease Positive IC50 163
prodiamine 4.84±0.56 human qHTS-HepG2 MMP assay decrease Positive IC50 163
profenofos 2.54±1.84 human qHTS-HepG2 MMP assay decrease Positive IC50 163
proflavin hemisulfate 3.22±0.82 human qHTS-HepG2 MMP assay decrease Positive IC50 163
proflavin hydrochloride 1.66±0.63 human qHTS-HepG2 MMP assay decrease Positive IC50 163
profluralin 21.69±8.04 human qHTS-HepG2 MMP assay decrease Positive IC50 163
propan-2-yl (2r,4s)-4-{acetyl[3,5-bis(trifluoromethyl)benzyl]amino}-2-ethyl-6-(trifluoromethyl)-3,4-dihydroquinoline-1(2h)-carboxylate 5.66±1.72 human qHTS-HepG2 MMP assay decrease Positive IC50 163
propyl gallate 42.29±3.93 human qHTS-HepG2 MMP assay decrease Positive IC50 163
propylparaben 38.60±1.67 human qHTS-HepG2 MMP assay decrease Positive IC50 163
proscillaridin 0.09±0.02 human qHTS-HepG2 MMP assay decrease Positive IC50 163
pyraclostrobin 6.35±1.92 human qHTS-HepG2 MMP assay decrease Positive IC50 163
pyridate 33.08±4.58 human qHTS-HepG2 MMP assay decrease Positive IC50 163
pyrinuron 26.28±1.71 human qHTS-HepG2 MMP assay decrease Positive IC50 163
pyrvinium pamoate 2.02±1.20 human qHTS-HepG2 MMP assay decrease Positive IC50 163
quercetin 2.69±2.26 human qHTS-HepG2 MMP assay decrease Positive IC50 163
quercetin dihydrate 6.20±2.32 human qHTS-HepG2 MMP assay decrease Positive IC50 163
rac benidipine hydrochloride 14.96±3.18 human qHTS-HepG2 MMP assay decrease Positive IC50 163
rafoxanide 3.27±1.76 human qHTS-HepG2 MMP assay decrease Positive IC50 163
raloxifene 5.05±3.99 human qHTS-HepG2 MMP assay decrease Positive IC50 163
raloxifene hydrochloride 6.69±1.65 human qHTS-HepG2 MMP assay decrease Positive IC50 163
resveratrol 1.60±0.43 human qHTS-HepG2 MMP assay decrease Positive IC50 163
Rhein 6.06±5.91 human qHTS-HepG2 MMP assay decrease Positive IC50 163
riboflavin 7.02±1.78 human qHTS-HepG2 MMP assay decrease Positive IC50 163
rifampicin 25.06±6.38 human qHTS-HepG2 MMP assay decrease Positive IC50 163
rifapentine 1.46±0.26 human qHTS-HepG2 MMP assay decrease Positive IC50 163
rimonabant 25.60±1.67 human qHTS-HepG2 MMP assay decrease Positive IC50 163
rolicyclidine 22.29±2.32 human qHTS-HepG2 MMP assay decrease Positive IC50 163
Rotenone 17.38±1.94 human qHTS-HepG2 MMP assay decrease Positive IC50 163
salicylanilide 3.71±1.27 human qHTS-HepG2 MMP assay decrease Positive IC50 163
selenious acid 15.97±22.77 human qHTS-HepG2 MMP assay decrease Positive IC50 163
siduron 41.65±21.12 human qHTS-HepG2 MMP assay decrease Positive IC50 163
silwet l77 5.66±1.03 human qHTS-HepG2 MMP assay decrease Positive IC50 163
rapamycin 20.08±2.07 human qHTS-HepG2 MMP assay decrease Positive IC50 163
sodium (4-fluoro-2-{[(1s)-1-phenylpropyl]carbamoyl}phenyl)(quinolin-8-ylsulfonyl)azanide 4.42±6.97 human qHTS-HepG2 MMP assay decrease Positive IC50 163
sodium 2-phenylphenate tetrahydrate 18.53±0.00 human qHTS-HepG2 MMP assay decrease Positive IC50 163
sodium bithionolate 0.91±0.78 human qHTS-HepG2 MMP assay decrease Positive IC50 163
sodium warfarin 38.57±12.82 human qHTS-HepG2 MMP assay decrease Positive IC50 163
sofalcone 24.64±1.67 human qHTS-HepG2 MMP assay decrease Positive IC50 163
sorafenib 0.96±0.09 human qHTS-HepG2 MMP assay decrease Positive IC50 163
sp600125 0.92±0.14 human qHTS-HepG2 MMP assay decrease Positive IC50 163
spiclomazine hydrochloride 34.80±2.36 human qHTS-HepG2 MMP assay decrease Positive IC50 163
spiperone 3.62±0.24 human qHTS-HepG2 MMP assay decrease Positive IC50 163
su-5416 12.53±1.78 human qHTS-HepG2 MMP assay decrease Positive IC50 163
sulfanitran 26.60±8.77 human qHTS-HepG2 MMP assay decrease Positive IC50 163
surinabant 33.08±16.61 human qHTS-HepG2 MMP assay decrease Positive IC50 163
talniflumate 27.00±2.56 human qHTS-HepG2 MMP assay decrease Positive IC50 163
tamibarotene 25.68±1.05 human qHTS-HepG2 MMP assay decrease Positive IC50 163
tamsulosin hydrochloride 27.20±2.92 human qHTS-HepG2 MMP assay decrease Positive IC50 163
tau-fluvalinate 37.16±15.12 human qHTS-HepG2 MMP assay decrease Positive IC50 163
tenidap 12.53±1.19 human qHTS-HepG2 MMP assay decrease Positive IC50 163
tenonitrozole 0.73±0.12 human qHTS-HepG2 MMP assay decrease Positive IC50 163
tenovin-1 3.27±2.74 human qHTS-HepG2 MMP assay decrease Positive IC50 163
tenoxicam 8.36±1.07 human qHTS-HepG2 MMP assay decrease Positive IC50 163
tert-butyl 4-hydroxybenzoate 25.29±7.32 human qHTS-HepG2 MMP assay decrease Positive IC50 163
tetra-aminopyrimidine sulfate 18.70±11.39 human qHTS-HepG2 MMP assay decrease Positive IC50 163
tetrabromophenolphthalein ethyl ester 23.80±6.89 human qHTS-HepG2 MMP assay decrease Positive IC50 163
tetrabutyltin 5.66±1.03 human qHTS-HepG2 MMP assay decrease Positive IC50 163
tetradecylpyridinium bromide 22.54±4.10 human qHTS-HepG2 MMP assay decrease Positive IC50 163
tetradifon 15.34±7.43 human qHTS-HepG2 MMP assay decrease Positive IC50 163
tetraiodoethene 5.45±1.27 human qHTS-HepG2 MMP assay decrease Positive IC50 163
tetra-n-octylammonium bromide 0.13±0.09 human qHTS-HepG2 MMP assay decrease Positive IC50 163
tetraoctylphosphonium bromide 0.18±0.12 human qHTS-HepG2 MMP assay decrease Positive IC50 163
tetrasul 1.77±0.25 human qHTS-HepG2 MMP assay decrease Positive IC50 163
thidiazuron 3.43±0.73 human qHTS-HepG2 MMP assay decrease Positive IC50 163
thiram 1.94±25.92 human qHTS-HepG2 MMP assay decrease Positive IC50 163
tibrofan 0.79±0.11 human qHTS-HepG2 MMP assay decrease Positive IC50 163
tioxidazole 7.50±1.75 human qHTS-HepG2 MMP assay decrease Positive IC50 163
Tipranavir 26.60±4.94 human qHTS-HepG2 MMP assay decrease Positive IC50 163
tolclofos-methyl 30.64±5.80 human qHTS-HepG2 MMP assay decrease Positive IC50 163
Tolfenamic Acid 11.88±0.00 human qHTS-HepG2 MMP assay decrease Positive IC50 163
toluidine blue 3.48±1.60 human qHTS-HepG2 MMP assay decrease Positive IC50 163
tolvaptan 17.44±8.01 human qHTS-HepG2 MMP assay decrease Positive IC50 163
transfluthrin 25.01±4.09 human qHTS-HepG2 MMP assay decrease Positive IC50 163
tribenoside 11.80±0.80 human qHTS-HepG2 MMP assay decrease Positive IC50 163
tribromosalan 1.12±0.00 human qHTS-HepG2 MMP assay decrease Positive IC50 163
tributyltetradecylphosphonium chloride 0.71±0.15 human qHTS-HepG2 MMP assay decrease Positive IC50 163
tributyltin benzoate 0.15±0.23 human qHTS-HepG2 MMP assay decrease Positive IC50 163
tributyltin chloride 0.11±0.02 human qHTS-HepG2 MMP assay decrease Positive IC50 163
tributyltin methacrylate 0.07±0.01 human qHTS-HepG2 MMP assay decrease Positive IC50 163
tricirbine 1.21±1.51 human qHTS-HepG2 MMP assay decrease Positive IC50 163
triclabendazole 1.84±0.15 human qHTS-HepG2 MMP assay decrease Positive IC50 163
triclocarban 0.14±0.05 human qHTS-HepG2 MMP assay decrease Positive IC50 163
triclosan 1.50±0.88 human qHTS-HepG2 MMP assay decrease Positive IC50 163
triethoxy(2-methylpropyl)silane 28.92±6.98 human qHTS-HepG2 MMP assay decrease Positive IC50 163
triethyltin bromide 0.02±0.02 human qHTS-HepG2 MMP assay decrease Positive IC50 163
trifluralin 46.68±9.14 human qHTS-HepG2 MMP assay decrease Positive IC50 163
trihexyltetradecylphosphonium bromide 0.84±0.24 human qHTS-HepG2 MMP assay decrease Positive IC50 163
trihexyltetradecylphosphonium chloride 0.77±0.35 human qHTS-HepG2 MMP assay decrease Positive IC50 163
trihexyltetradecylphosphonium dicyanamide 0.39±0.19 human qHTS-HepG2 MMP assay decrease Positive IC50 163
trihexyltetradecylphosphonium hexafluorophosphate 0.43±0.17 human qHTS-HepG2 MMP assay decrease Positive IC50 163
triphenyl phosphate 1.38±1.48 human qHTS-HepG2 MMP assay decrease Positive IC50 163
triphenylethylene 35.72±14.82 human qHTS-HepG2 MMP assay decrease Positive IC50 163
triphenyltin acetate 0.12±0.04 human qHTS-HepG2 MMP assay decrease Positive IC50 163
triphenyltin fluoride 0.47±0.31 human qHTS-HepG2 MMP assay decrease Positive IC50 163
triphenyltin hydroxide 0.12±0.03 human qHTS-HepG2 MMP assay decrease Positive IC50 163
tris(2,3-dibromopropyl) phosphate 45.81±8.72 human qHTS-HepG2 MMP assay decrease Positive IC50 163
Tyrothricin 0.24±0.05 human qHTS-HepG2 MMP assay decrease Positive IC50 163
tyrphostin 23 17.70±6.46 human qHTS-HepG2 MMP assay decrease Positive IC50 163
vatalanib 25.60±4.41 human qHTS-HepG2 MMP assay decrease Positive IC50 163
Verteporfin 3.27±1.85 human qHTS-HepG2 MMP assay decrease Positive IC50 163
zafirlukast 10.59±1.22 human qHTS-HepG2 MMP assay decrease Positive IC50 163
zearalenone 4.67±1.77 human qHTS-HepG2 MMP assay decrease Positive IC50 163
(1,1,3,3-tetramethylbutyl)phenol 3.98 human HepG2 MMP assay decrease Positive IC50 163
(1'-ethyl-6,7-dihydro-5h-spiro[furo[2,3-f]indole-3,4'-piperidin]-5-yl)[2'-methyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-yl]methanone hydrochloride 19.95 human HepG2 MMP assay decrease Positive IC50 163
(2-ethyl-4-{[(4-{[4-(4-methoxyphenyl)piperazin-1-yl]methyl}-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl)methyl]sulfanyl}phenoxy)acetic acid 31.62 human HepG2 MMP assay decrease Positive IC50 163
(5-chloro-2-hydroxyphenyl)phenylmethanone 39.81 human HepG2 MMP assay decrease Positive IC50 163
(5s,8s)-5-(3,4-dichlorophenyl)-8-(methylamino)-5,6,7,8-tetrahydronaphthalene-2-sulfonamide 10 human HepG2 MMP assay decrease Positive IC50 163
(acryloyloxy)(tributyl)stannane 0.4 human HepG2 MMP assay decrease Positive IC50 163
(n-6)-methyladenine 6.31 human HepG2 MMP assay decrease Positive IC50 163
Diethylstilbestrol 5.62 human HepG2 MMP assay decrease Positive IC50 163
1-(2,3,8,8-tetramethyl-1,2,3,4,5,6,7,8-octahydronaphthalen-2-yl)ethanone 35.48 human HepG2 MMP assay decrease Positive IC50 163
1-(3,5,5,6,8,8-hexamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethanone 28.18 human HepG2 MMP assay decrease Positive IC50 163
1,1,1-trichloropropanone 3.16 human HepG2 MMP assay decrease Positive IC50 163
1,1,2-trimethyl-1h-benzo[e]indole 10 human HepG2 MMP assay decrease Positive IC50 163
1,1':3',1''-terphenyl 50.12 human HepG2 MMP assay decrease Positive IC50 163
1,2,5,6,9,10-hexabromocyclododecane 6.31 human HepG2 MMP assay decrease Positive IC50 163
1,2-benzisothiazolin-3-one 17.78 human HepG2 MMP assay decrease Positive IC50 163
1,2-phenylenediamine 2.51 human HepG2 MMP assay decrease Positive IC50 163
1,2-phenylenediamine dihydrochloride 1.78 human HepG2 MMP assay decrease Positive IC50 163
1,3,5-tris(4-tert-butyl-3-hydroxy-2,6-dimethylbenzyl)-1,3,5-triazinane-2,4,6-trione 44.67 human HepG2 MMP assay decrease Positive IC50 163
1,3-didecyl-2-methylimidazolium chloride 3.16 human HepG2 MMP assay decrease Positive IC50 163
1,3-diiminobenz(f)isoindoline 35.48 human HepG2 MMP assay decrease Positive IC50 163
1,3-diphenyl-1,3-propanedione 35.48 human HepG2 MMP assay decrease Positive IC50 163
1,4-benzenediamine 2.18 human HepG2 MMP assay decrease Positive IC50 163
1,4-diaminoanthraquinone 0.22 human HepG2 MMP assay decrease Positive IC50 163
1,4-dihydroxyanthracene-9,10-dione 8.91 human HepG2 MMP assay decrease Positive IC50 163
1,4-naphthalenediamine 2 human HepG2 MMP assay decrease Positive IC50 163
1,5-naphthalenediamine 3.16 human HepG2 MMP assay decrease Positive IC50 163
1,8-dihydroxy-4,5-dinitroanthraquinone 0.45 human HepG2 MMP assay decrease Positive IC50 163
Mito-4509 22.39 human HepG2 MMP assay decrease Positive IC50 163
17alpha-ethinylestradiol 15.45 human HepG2 MMP assay decrease Positive IC50 163
1-amino-2-methylanthraquinone 2.51 human HepG2 MMP assay decrease Positive IC50 163
1-benzyl-1-{[3-(4-chlorophenyl)-5-methyl-1-benzofuran-2-yl]methyl}-3-(2,4,6-trifluorophenyl)urea 56.23 human HepG2 MMP assay decrease Positive IC50 163
1-decyl-3-methylimidazolium tetrafluoroborate 7.08 human HepG2 MMP assay decrease Positive IC50 163
1-decyl-3-methylimidazolium trifluoromethanesulfonate 7.08 human HepG2 MMP assay decrease Positive IC50 163
1-dodecyl-3-methylimidazolium hexafluorophosphate 5.01 human HepG2 MMP assay decrease Positive IC50 163
1-fluoro-2,4-dinitrobenzene 5.48 human HepG2 MMP assay decrease Positive IC50 163
1h,3h-naphtho(1,8-cd)pyran-1,3-dione 7.94 human HepG2 MMP assay decrease Positive IC50 163
1h-benzo[de]isoquinoline-1,3(2h)-dione 14.13 human HepG2 MMP assay decrease Positive IC50 163
1h-indole-2-carboxamide, n-[(3r)-1-(2-fluorophenyl)-3,4,6,7-tetrahydro-4-oxopyrrolo[3,2,1-jk][1,4]benzodiazepin-3-yl]- 13.77 human HepG2 MMP assay decrease Positive IC50 163
1-hydroxypyrene 7.08 human HepG2 MMP assay decrease Positive IC50 163
1-isocyanato-3-(trifluoromethyl)benzene 6.31 human HepG2 MMP assay decrease Positive IC50 163
1-methyl-3-octylimidazolium hexafluorophosphate 25.12 human HepG2 MMP assay decrease Positive IC50 163
1-methyl-3-octylimidazolium tetrafluoroborate 19.95 human HepG2 MMP assay decrease Positive IC50 163
1-methyl-3-octylimidazolium trifluoromethanesulfonate 15.85 human HepG2 MMP assay decrease Positive IC50 163
1-methylpyrene 39.81 human HepG2 MMP assay decrease Positive IC50 163
1-naphthol 31.62 human HepG2 MMP assay decrease Positive IC50 163
1-nitropyrene 6.31 human HepG2 MMP assay decrease Positive IC50 163
Edaravone 28.18 human HepG2 MMP assay decrease Positive IC50 163
1-trans-delta-9-tetrahydrocannabinol 15.45 human HepG2 MMP assay decrease Positive IC50 163
2-(4-hydroxybenzyl)phenol 35.48 human HepG2 MMP assay decrease Positive IC50 163
2-(butan-2-yl)phenol 25.12 human HepG2 MMP assay decrease Positive IC50 163
2-(thiocyanomethylthio)benzothiazole 56.23 human HepG2 MMP assay decrease Positive IC50 163
2,2',4,4',5-pentabromodiphenyl ether 4.47 human HepG2 MMP assay decrease Positive IC50 163
2,2',6,6'-tetrachlorobisphenol a 6.31 human HepG2 MMP assay decrease Positive IC50 163
2,2'4,4'-tetrabromodiphenyl ether 39.81 human HepG2 MMP assay decrease Positive IC50 163
2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane 10 human HepG2 MMP assay decrease Positive IC50 163
2,2-bis[(benzoyloxy)methyl]dibenzoate propanediol 7.08 human HepG2 MMP assay decrease Positive IC50 163
2,2'-dichlorobiphenyl 63.1 human HepG2 MMP assay decrease Positive IC50 163
2,2'-dihydroxy-4,4'-dimethoxybenzophenone 12.59 human HepG2 MMP assay decrease Positive IC50 163
2,2'-dihydroxy-4-methoxybenzophenone 5.24 human HepG2 MMP assay decrease Positive IC50 163
2,2'-methylenebis(4-methyl-6-tert-butylphenol) 2 human HepG2 MMP assay decrease Positive IC50 163
2,2'-methylenebis(ethyl-6-tert-butylphenol) 2 human HepG2 MMP assay decrease Positive IC50 163
2,3',4,4'-tetrahydroxybenzophenone 8.91 human HepG2 MMP assay decrease Positive IC50 163
2,3,4,5-tetrachlorophenol 7.94 human HepG2 MMP assay decrease Positive IC50 163
2,3,4-trichlorophenol 7.94 human HepG2 MMP assay decrease Positive IC50 163
2,3,5,6-tetrachlorophenol 8.91 human HepG2 MMP assay decrease Positive IC50 163
2,3,5-trichlorophenol 6.31 human HepG2 MMP assay decrease Positive IC50 163
2,4,5-trichlorophenol sodium salt 10 human HepG2 MMP assay decrease Positive IC50 163
2,4,6-trinitro-1,3-dimethyl-5-tert-butylbenzene 7.94 human HepG2 MMP assay decrease Positive IC50 163
2,4-bis(1-methyl-1-phenylethyl)phenol 2.82 human HepG2 MMP assay decrease Positive IC50 163
2,4-diaminoanisole sulfate 7.94 human HepG2 MMP assay decrease Positive IC50 163
2,4-dichloro-3,5-dimethylphenol 8.91 human HepG2 MMP assay decrease Positive IC50 163
2,4-diisopropylphenol 35.48 human HepG2 MMP assay decrease Positive IC50 163
2,4-di-tert-butylphenol 3.98 human HepG2 MMP assay decrease Positive IC50 163
2,5-bis(2-methylbutan-2-yl)benzene-1,4-diol 3.55 human HepG2 MMP assay decrease Positive IC50 163
2,5-di-tert-butylbenzene-1,4-diol 7.94 human HepG2 MMP assay decrease Positive IC50 163
2,6-bis-(1,1-dimethylethyl)-2,5-cyclohexadiene-1,4-dione 39.81 human HepG2 MMP assay decrease Positive IC50 163
2,6-di(butan-2-yl)phenol 15.85 human HepG2 MMP assay decrease Positive IC50 163
2,6-diaminopyridine 35.48 human HepG2 MMP assay decrease Positive IC50 163
2,6-di-tert-butyl-4-nitrophenol 0.11 human HepG2 MMP assay decrease Positive IC50 163
2,6-toluenediamine 28.18 human HepG2 MMP assay decrease Positive IC50 163
24r,25-dihydroxyvitamin d3 15.45 human HepG2 MMP assay decrease Positive IC50 163
2-Acetylaminofluorene 31.62 human HepG2 MMP assay decrease Positive IC50 163
2-amino-4-(p-nitrophenyl)thiazole 8.91 human HepG2 MMP assay decrease Positive IC50 163
2-amino-4,6-dinitrophenol 15.85 human HepG2 MMP assay decrease Positive IC50 163
2-amino-4-chloro-5-nitrophenol 25.12 human HepG2 MMP assay decrease Positive IC50 163
2-amino-4-chlorobenzothiazole 31.62 human HepG2 MMP assay decrease Positive IC50 163
2-amino-5-nitrophenol 35.48 human HepG2 MMP assay decrease Positive IC50 163
2-amino-6-nitrobenzothiazole 44.67 human HepG2 MMP assay decrease Positive IC50 163
2-aminoanthracene 3.55 human HepG2 MMP assay decrease Positive IC50 163
2-aminoanthraquinone 1.26 human HepG2 MMP assay decrease Positive IC50 163
2-chloro-4-phenylphenol 15.85 human HepG2 MMP assay decrease Positive IC50 163
2-dodecylisoquinolinium tosylate 4.35 human HepG2 MMP assay decrease Positive IC50 163
2-ethylphenol 15.85 human HepG2 MMP assay decrease Positive IC50 163
2-hydrazino-4-(4-aminophenyl) thiazole 0.4 human HepG2 MMP assay decrease Positive IC50 163
2-hydrazino-4-(4-nitrophenyl)thiazole 1.26 human HepG2 MMP assay decrease Positive IC50 163
2-hydrazino-4-phenylthiazole 10 human HepG2 MMP assay decrease Positive IC50 163
2-hydroxyanthraquinone 7.08 human HepG2 MMP assay decrease Positive IC50 163
2-isovaleryl-1,3-indanedione 56.23 human HepG2 MMP assay decrease Positive IC50 163
2-methyl-1-nitroanthraquinone 2.77 human HepG2 MMP assay decrease Positive IC50 163
2-methylanthraquinone 11.22 human HepG2 MMP assay decrease Positive IC50 163
2-naphthalenesulfonic acid, 7-amino-4-hydroxy- 39.81 human HepG2 MMP assay decrease Positive IC50 163
2-naphthalenol 35.48 human HepG2 MMP assay decrease Positive IC50 163
2-nitro-1,4-phenylenediamine 12.59 human HepG2 MMP assay decrease Positive IC50 163
2-nitrofluorene 50.12 human HepG2 MMP assay decrease Positive IC50 163
2-phenylphenol 28.18 human HepG2 MMP assay decrease Positive IC50 163
2-propenal,3,3-diphenyl- 56.23 human HepG2 MMP assay decrease Positive IC50 163
2-tert-butyl-4-ethylphenol 15.85 human HepG2 MMP assay decrease Positive IC50 163
2-tert-butyl-4-methoxyphenol 35.48 human HepG2 MMP assay decrease Positive IC50 163
2-tert-butyl-5-methylphenol 5.01 human HepG2 MMP assay decrease Positive IC50 163
3-(5,5,6-trimethylbicyclo[2.2.1]hept-2-yl)cyclohexanol 39.81 human HepG2 MMP assay decrease Positive IC50 163
3,3',4,4'-tetraaminobiphenyl tetrahydrochloride 2 human HepG2 MMP assay decrease Positive IC50 163
3,3',5,5'-tetraiodothyroacetic acid 39.04 human HepG2 MMP assay decrease Positive IC50 163
3,3'-diaminobenzidine 4.47 human HepG2 MMP assay decrease Positive IC50 163
3,3'-dimethylbisphenol a 11.22 human HepG2 MMP assay decrease Positive IC50 163
3,3φ,5,5φ-tetrabromobisphenol a 17.78 human HepG2 MMP assay decrease Positive IC50 163
3,4,5-trichlorophenol 5.01 human HepG2 MMP assay decrease Positive IC50 163
3,4-dichlorophenol 15.85 human HepG2 MMP assay decrease Positive IC50 163
3,5-dichlorophenol 11.22 human HepG2 MMP assay decrease Positive IC50 163
3,5-dichlorosalicyl-3,4-dichloroanilide 0.11 human HepG2 MMP assay decrease Positive IC50 163
3-acetylphenanthrene 56.23 human HepG2 MMP assay decrease Positive IC50 163
3-amino-9-ethylcarbazole hydrochloride 14.13 human HepG2 MMP assay decrease Positive IC50 163
3-hydroxybenzophenone 39.81 human HepG2 MMP assay decrease Positive IC50 163
3-hydroxy-n-(3-nitrophenyl)naphthalene-2-carboxamide 0.28 human HepG2 MMP assay decrease Positive IC50 163
3-hydroxy-n-phenylaniline 35.48 human HepG2 MMP assay decrease Positive IC50 163
3-methylbenzene-1,2-diamine 28.18 human HepG2 MMP assay decrease Positive IC50 163
3-methylcholanthrene 25.19 human HepG2 MMP assay decrease Positive IC50 163
3-methyl-n-phenylaniline 28.18 human HepG2 MMP assay decrease Positive IC50 163
4-(1,1,3,3-tetramethylbutyl)phenol 4.89 human HepG2 MMP assay decrease Positive IC50 163
4-(2-methylbutan-2-yl)phenol 35.48 human HepG2 MMP assay decrease Positive IC50 163
4-(3-phenylpropyl)pyridine 14.13 human HepG2 MMP assay decrease Positive IC50 163
4-(benzyloxyl)phenol 7.4 human HepG2 MMP assay decrease Positive IC50 163
4-(butan-2-yl)phenol 35.48 human HepG2 MMP assay decrease Positive IC50 163
4,4,4-trifluoro-1-phenyl-1,3-butanedione 31.62 human HepG2 MMP assay decrease Positive IC50 163
4,4'-diaminoazobenzene 5.62 human HepG2 MMP assay decrease Positive IC50 163
4,4'-diaminobenzanilide 7.08 human HepG2 MMP assay decrease Positive IC50 163
4,4'-dichlorodiphenyl sulfone 35.48 human HepG2 MMP assay decrease Positive IC50 163
4,4'-dinitrodiphenylurea 0.97 human HepG2 MMP assay decrease Positive IC50 163
4,4'-methylenebis(2-chloroaniline) 39.81 human HepG2 MMP assay decrease Positive IC50 163
4,4'-sulfonylbis[2-(prop-2-en-1-yl)phenol] 15.85 human HepG2 MMP assay decrease Positive IC50 163
4,4'-thiobis(6-tert-butyl-m-cresol) 3.16 human HepG2 MMP assay decrease Positive IC50 163
4,4'-thiodiphenol 25.12 human HepG2 MMP assay decrease Positive IC50 163
4,6-dichloro-1,3-benzenediol 15.85 human HepG2 MMP assay decrease Positive IC50 163
4,6-di-tert-butyl-m-cresol 2.51 human HepG2 MMP assay decrease Positive IC50 163
4-amino-2,6-dichlorophenol 15.85 human HepG2 MMP assay decrease Positive IC50 163
4-amino-2-nitrophenol 14.13 human HepG2 MMP assay decrease Positive IC50 163
4-amino-4φ-hydroxy-3-methyldiphenylamine 14.13 human HepG2 MMP assay decrease Positive IC50 163
4-benzylphenol 31.62 human HepG2 MMP assay decrease Positive IC50 163
4-chloro-1,2-diaminobenzene 2 human HepG2 MMP assay decrease Positive IC50 163
4-chloro-2-cyclopentylphenol 6.31 human HepG2 MMP assay decrease Positive IC50 163
4-chloro-3,5-dimethylphenol 25.12 human HepG2 MMP assay decrease Positive IC50 163
4-chlorophenyl isocyanate 0.71 human HepG2 MMP assay decrease Positive IC50 163
4-cumylphenol 3.55 human HepG2 MMP assay decrease Positive IC50 163
4'-demethylepipodophyllotoxin 2.18 human HepG2 MMP assay decrease Positive IC50 163
4-dodecylphenol 5.01 human HepG2 MMP assay decrease Positive IC50 163
4-hexyl-4'-cyanobiphenyl 31.62 human HepG2 MMP assay decrease Positive IC50 163
4-hydroxybenzophenone 28.18 human HepG2 MMP assay decrease Positive IC50 163
4-methyl-2,6-dinitrophenol 35.48 human HepG2 MMP assay decrease Positive IC50 163
4-nitroanthranilic acid 17.78 human HepG2 MMP assay decrease Positive IC50 163
4-nitro-n-phenylaniline 8.91 human HepG2 MMP assay decrease Positive IC50 163
4-nitrosophenol 15.85 human HepG2 MMP assay decrease Positive IC50 163
4-octylphenol 14.13 human HepG2 MMP assay decrease Positive IC50 163
4-phenoxyphenol 47.57 human HepG2 MMP assay decrease Positive IC50 163
4-tert-butylcatechol 31.62 human HepG2 MMP assay decrease Positive IC50 163
4-tert-butylphenyl salicylate 35.48 human HepG2 MMP assay decrease Positive IC50 163
5,7-dichloro-8-hydroxy-2-methylquinoline 1.38 human HepG2 MMP assay decrease Positive IC50 163
5alpha-dihydrotestosterone 17.34 human HepG2 MMP assay decrease Positive IC50 163
5hpp-33 2.24 human HepG2 MMP assay decrease Positive IC50 163
Busulfan 2 human HepG2 MMP assay decrease Positive IC50 163
5-nitroacenaphthene 56.23 human HepG2 MMP assay decrease Positive IC50 163
6-hydroxy-2-naphthyl disulfide 28.18 human HepG2 MMP assay decrease Positive IC50 163
9-aminoacridine, monohydrochloride, monohydrate 21.82 human HepG2 MMP assay decrease Positive IC50 163
9-anthracenemethanol 19.95 human HepG2 MMP assay decrease Positive IC50 163
9-nitroanthracene 35.48 human HepG2 MMP assay decrease Positive IC50 163
9-phenanthrol 3.55 human HepG2 MMP assay decrease Positive IC50 163
acenocoumarol 9.32 human HepG2 MMP assay decrease Positive IC50 163
aclarubicin hydrochloride 2.45 human HepG2 MMP assay decrease Positive IC50 163
acriflavine hydrochloride 0.44 human HepG2 MMP assay decrease Positive IC50 163
Albendazole 19.45 human HepG2 MMP assay decrease Positive IC50 163
aldrin 39.81 human HepG2 MMP assay decrease Positive IC50 163
alizarin 13.77 human HepG2 MMP assay decrease Positive IC50 163
allylestrenol 31.62 human HepG2 MMP assay decrease Positive IC50 163
aloe-emodin 7.08 human HepG2 MMP assay decrease Positive IC50 163
alpha-amylcinnamyl alcohol 56.23 human HepG2 MMP assay decrease Positive IC50 163
ambazone 3.98 human HepG2 MMP assay decrease Positive IC50 163
ami-193 7.74 human HepG2 MMP assay decrease Positive IC50 163
aminoquinuride dihydrochloride 27.48 human HepG2 MMP assay decrease Positive IC50 163
amorolfine 17.34 human HepG2 MMP assay decrease Positive IC50 163
amsacrine hydrochloride 56.23 human HepG2 MMP assay decrease Positive IC50 163
amylmetacresol 8.69 human HepG2 MMP assay decrease Positive IC50 163
apigenin 3.55 human HepG2 MMP assay decrease Positive IC50 163
aroclor 1260 12.59 human HepG2 MMP assay decrease Positive IC50 163
arotinolol hydrochloride 27.48 human HepG2 MMP assay decrease Positive IC50 163
axitinib 1.09 human HepG2 MMP assay decrease Positive IC50 163
barban 25.12 human HepG2 MMP assay decrease Positive IC50 163
bardoxolone methyl 17.34 human HepG2 MMP assay decrease Positive IC50 163
barium chloride 39.81 human HepG2 MMP assay decrease Positive IC50 163
basic blue 7 0.05 human HepG2 MMP assay decrease Positive IC50 163
bazedoxifene 15.45 human HepG2 MMP assay decrease Positive IC50 163
beclazone 21.82 human HepG2 MMP assay decrease Positive IC50 163
benzbromarone 13.77 human HepG2 MMP assay decrease Positive IC50 163
benzidine 15.85 human HepG2 MMP assay decrease Positive IC50 163
benzidine dihydrochloride 17.65 human HepG2 MMP assay decrease Positive IC50 163
benziodarone 4.35 human HepG2 MMP assay decrease Positive IC50 163
benzoic acid, 2-[(4-chloro-3-methylphenyl)amino]- 35.48 human HepG2 MMP assay decrease Positive IC50 163
benzyldimethyltetradecylammonium chloride dihydrate 13.77 human HepG2 MMP assay decrease Positive IC50 163
benzyldodecyldimethylammonium bromide 17.34 human HepG2 MMP assay decrease Positive IC50 163
benzylhydrazine dihydrochloride 19.95 human HepG2 MMP assay decrease Positive IC50 163
berberine chloride 3.46 human HepG2 MMP assay decrease Positive IC50 163
betamethasone dipropionate 19.45 human HepG2 MMP assay decrease Positive IC50 163
bexarotene 8.69 human HepG2 MMP assay decrease Positive IC50 163
bis(tributyltin)oxide 0.31 human HepG2 MMP assay decrease Positive IC50 163
bisacodyl 7.74 human HepG2 MMP assay decrease Positive IC50 163
Bisphenol A 15.85 human HepG2 MMP assay decrease Positive IC50 163
bisphenol a glycidyl methacrylate 15.85 human HepG2 MMP assay decrease Positive IC50 163
bisphenol af 5.01 human HepG2 MMP assay decrease Positive IC50 163
bisphenol b 10 human HepG2 MMP assay decrease Positive IC50 163
bisphenol e 25.12 human HepG2 MMP assay decrease Positive IC50 163
bisphenol z 19.95 human HepG2 MMP assay decrease Positive IC50 163
bithionol 0.97 human HepG2 MMP assay decrease Positive IC50 163
bosutinib 1.23 human HepG2 MMP assay decrease Positive IC50 163
bromadiolone 4.35 human HepG2 MMP assay decrease Positive IC50 163
bromociclen 15.45 human HepG2 MMP assay decrease Positive IC50 163
bromocriptine 21.82 human HepG2 MMP assay decrease Positive IC50 163
bromocriptine mesylate 13.5 human HepG2 MMP assay decrease Positive IC50 163
bromofenoxim 3.98 human HepG2 MMP assay decrease Positive IC50 163
bromofos 8.91 human HepG2 MMP assay decrease Positive IC50 163
bromoxynil octanoate 31.62 human HepG2 MMP assay decrease Positive IC50 163
broquinaldol 12.59 human HepG2 MMP assay decrease Positive IC50 163
bryostatin 1 0.001 human HepG2 MMP assay decrease Positive IC50 163
butylparaben 35.48 human HepG2 MMP assay decrease Positive IC50 163
c.i. 1040 7.74 human HepG2 MMP assay decrease Positive IC50 163
c.i. basic orange 2 19.95 human HepG2 MMP assay decrease Positive IC50 163
c.i. basic red 9 monohydrochloride 0.56 human HepG2 MMP assay decrease Positive IC50 163
c.i. basic violet 14 0.87 human HepG2 MMP assay decrease Positive IC50 163
c.i. disperse blue 27 25.12 human HepG2 MMP assay decrease Positive IC50 163
c.i. solvent yellow 14 15.85 human HepG2 MMP assay decrease Positive IC50 163
calcifediol 12.27 human HepG2 MMP assay decrease Positive IC50 163
calcipotriene 21.82 human HepG2 MMP assay decrease Positive IC50 163
calcitriol 15.45 human HepG2 MMP assay decrease Positive IC50 163
candesartan cilexetil 11.22 human HepG2 MMP assay decrease Positive IC50 163
cannabinol 1.09 human HepG2 MMP assay decrease Positive IC50 163
cantharidin 0.12 human HepG2 MMP assay decrease Positive IC50 163
CCCP 0.25 human HepG2 MMP assay decrease Positive IC50 163
carminomycin 21.82 human HepG2 MMP assay decrease Positive IC50 163
chlorfenapyr 0.04 human HepG2 MMP assay decrease Positive IC50 163
chlorfenethol 12.59 human HepG2 MMP assay decrease Positive IC50 163
chlorfenson 44.67 human HepG2 MMP assay decrease Positive IC50 163
chlorfluazuron 12.59 human HepG2 MMP assay decrease Positive IC50 163
chlorophacinone 3.55 human HepG2 MMP assay decrease Positive IC50 163
chloropropylate 44.67 human HepG2 MMP assay decrease Positive IC50 163
chloroxine 9.75 human HepG2 MMP assay decrease Positive IC50 163
chromomycin 35.48 human HepG2 MMP assay decrease Positive IC50 163
chrysarobin 30.83 human HepG2 MMP assay decrease Positive IC50 163
chrysin 7.08 human HepG2 MMP assay decrease Positive IC50 163
ciclesonide 15.45 human HepG2 MMP assay decrease Positive IC50 163
Ciglitazone 14.13 human HepG2 MMP assay decrease Positive IC50 163
cilnidipine 12.27 human HepG2 MMP assay decrease Positive IC50 163
cinalukast 17.34 human HepG2 MMP assay decrease Positive IC50 163
clobetasol 17.34 human HepG2 MMP assay decrease Positive IC50 163
cloflucarban 0.44 human HepG2 MMP assay decrease Positive IC50 163
clofoctol 4.35 human HepG2 MMP assay decrease Positive IC50 163
clonixin 22.39 human HepG2 MMP assay decrease Positive IC50 163
cloxyquin 15.45 human HepG2 MMP assay decrease Positive IC50 163
coumatetralyl 35.48 human HepG2 MMP assay decrease Positive IC50 163
cresyl diphenyl phosphate 3.55 human HepG2 MMP assay decrease Positive IC50 163
curcumin 2.51 human HepG2 MMP assay decrease Positive IC50 163
d&c yellow 11 0.44 human HepG2 MMP assay decrease Positive IC50 163
danthron 15.45 human HepG2 MMP assay decrease Positive IC50 163
dantrolene sodium 3.46 human HepG2 MMP assay decrease Positive IC50 163
darbufelone mesylate 5.62 human HepG2 MMP assay decrease Positive IC50 163
deltamethrin 50.12 human HepG2 MMP assay decrease Positive IC50 163
deslanoside 0.44 human HepG2 MMP assay decrease Positive IC50 163
desogestrel 27.48 human HepG2 MMP assay decrease Positive IC50 163
devazepide 10.94 human HepG2 MMP assay decrease Positive IC50 163
dexamethasone valerate 17.34 human HepG2 MMP assay decrease Positive IC50 163
diacerein 17.34 human HepG2 MMP assay decrease Positive IC50 163
dianiline 21.82 human HepG2 MMP assay decrease Positive IC50 163
dibutyltin dilaurate 27.48 human HepG2 MMP assay decrease Positive IC50 163
dichlofluanid 25.12 human HepG2 MMP assay decrease Positive IC50 163
dichlorodiphenylsilane 22.39 human HepG2 MMP assay decrease Positive IC50 163
diclazuril 8.69 human HepG2 MMP assay decrease Positive IC50 163
dicofol 8.91 human HepG2 MMP assay decrease Positive IC50 163
N,N'-dicyclohexylcarbodiimide 0.02 human HepG2 MMP assay decrease Positive IC50 163
dienestrol 8.3 human HepG2 MMP assay decrease Positive IC50 163
Diethylstilbestrol 6.31 human HepG2 MMP assay decrease Positive IC50 163
diethylstilbestrol dipropionate 7.08 human HepG2 MMP assay decrease Positive IC50 163
digitoxin 0.06 human HepG2 MMP assay decrease Positive IC50 163
digoxin 0.13 human HepG2 MMP assay decrease Positive IC50 163
dinex 0.71 human HepG2 MMP assay decrease Positive IC50 163
diniconazole 8.91 human HepG2 MMP assay decrease Positive IC50 163
dinobuton 7.94 human HepG2 MMP assay decrease Positive IC50 163
dinocap 0.63 human HepG2 MMP assay decrease Positive IC50 163
dinoterb 2.24 human HepG2 MMP assay decrease Positive IC50 163
diphenan 19.95 human HepG2 MMP assay decrease Positive IC50 163
diphenoxylate hydrochloride 17.34 human HepG2 MMP assay decrease Positive IC50 163
diphenylcyclopropenone 27.48 human HepG2 MMP assay decrease Positive IC50 163
diphenylurea 2.51 human HepG2 MMP assay decrease Positive IC50 163
disperse red 82 6.31 human HepG2 MMP assay decrease Positive IC50 163
dithiazanine chloride 0.15 human HepG2 MMP assay decrease Positive IC50 163
dithiazanine iodide 0.03 human HepG2 MMP assay decrease Positive IC50 163
dodecyl gallate 7.94 human HepG2 MMP assay decrease Positive IC50 163
dodecylparaben 7.94 human HepG2 MMP assay decrease Positive IC50 163
dodecylphenol 3.16 human HepG2 MMP assay decrease Positive IC50 163
doramapimod;bibr-796? 21.82 human HepG2 MMP assay decrease Positive IC50 163
doramectin 17.34 human HepG2 MMP assay decrease Positive IC50 163
ebselen 19.45 human HepG2 MMP assay decrease Positive IC50 163
emodin 2.51 human HepG2 MMP assay decrease Positive IC50 163
endosulfan sulfate 17.78 human HepG2 MMP assay decrease Positive IC50 163
endrin 21.82 human HepG2 MMP assay decrease Positive IC50 163
enterolactone 10.72 human HepG2 MMP assay decrease Positive IC50 163
eprinomectin (b1a, b1b mixture) 8.69 human HepG2 MMP assay decrease Positive IC50 163
equilin 31.62 human HepG2 MMP assay decrease Positive IC50 163
estradiol acetate 17.34 human HepG2 MMP assay decrease Positive IC50 163
ethacridine lactate hydrate 5.48 human HepG2 MMP assay decrease Positive IC50 163
ethalfluralin 44.67 human HepG2 MMP assay decrease Positive IC50 163
ethanol, 2,2'-((1-methylethylidene)bis((2,6-dibromo-4,1-phenylene)oxy))bis- 10.97 human HepG2 MMP assay decrease Positive IC50 163
ethoxazene 2.82 human HepG2 MMP assay decrease Positive IC50 163
ethynodiol diacetate 21.82 human HepG2 MMP assay decrease Positive IC50 163
etocarlide 25.12 human HepG2 MMP assay decrease Positive IC50 163
everolimus 27.48 human HepG2 MMP assay decrease Positive IC50 163
ezetimibe 8.69 human HepG2 MMP assay decrease Positive IC50 163
famoxadone 4.47 human HepG2 MMP assay decrease Positive IC50 163
fenamidone 19.95 human HepG2 MMP assay decrease Positive IC50 163
fenarimol 35.48 human HepG2 MMP assay decrease Positive IC50 163
fenchlorphos 6.15 human HepG2 MMP assay decrease Positive IC50 163
fendiline hydrochloride 9.75 human HepG2 MMP assay decrease Positive IC50 163
fenhexamid 17.78 human HepG2 MMP assay decrease Positive IC50 163
fenretinide 4.89 human HepG2 MMP assay decrease Positive IC50 163
fentiazac 19.45 human HepG2 MMP assay decrease Positive IC50 163
fenticlor 5.48 human HepG2 MMP assay decrease Positive IC50 163
fenvalerate 35.48 human HepG2 MMP assay decrease Positive IC50 163
flopropione 17.34 human HepG2 MMP assay decrease Positive IC50 163
fluazuron 12.27 human HepG2 MMP assay decrease Positive IC50 163
flubendiamide 25.33 human HepG2 MMP assay decrease Positive IC50 163
flucythrinate 31.62 human HepG2 MMP assay decrease Positive IC50 163
Flufenamic Acid 17.34 human HepG2 MMP assay decrease Positive IC50 163
flunixin meglumine 7.4 human HepG2 MMP assay decrease Positive IC50 163
fluorodifen 28.18 human HepG2 MMP assay decrease Positive IC50 163
fluorosalan 0.19 human HepG2 MMP assay decrease Positive IC50 163
fluoxastrobin 11.22 human HepG2 MMP assay decrease Positive IC50 163
folpet 14.13 human HepG2 MMP assay decrease Positive IC50 163
forchlorfenuron 1 human HepG2 MMP assay decrease Positive IC50 163
formononetin 17.78 human HepG2 MMP assay decrease Positive IC50 163
fulvestrant 5.48 human HepG2 MMP assay decrease Positive IC50 163
geliomycin 0.19 human HepG2 MMP assay decrease Positive IC50 163
genistein 10 human HepG2 MMP assay decrease Positive IC50 163
gentian violet 0.35 human HepG2 MMP assay decrease Positive IC50 163
gramicidin 0.04 human HepG2 MMP assay decrease Positive IC50 163
halobetasol propionate 13.77 human HepG2 MMP assay decrease Positive IC50 163
heptachlor 31.62 human HepG2 MMP assay decrease Positive IC50 163
Hexachlorophene 0.63 human HepG2 MMP assay decrease Positive IC50 163
indole-3-pyruvic acid 11.22 human HepG2 MMP assay decrease Positive IC50 163
indoxacarb 15.27 human HepG2 MMP assay decrease Positive IC50 163
iodophthalein 4.35 human HepG2 MMP assay decrease Positive IC50 163
iodophthalein sodium 6.9 human HepG2 MMP assay decrease Positive IC50 163
isobutylparaben 14.13 human HepG2 MMP assay decrease Positive IC50 163
isodrin 35.48 human HepG2 MMP assay decrease Positive IC50 163
isoxaben 14.13 human HepG2 MMP assay decrease Positive IC50 163
isoxicam 2.75 human HepG2 MMP assay decrease Positive IC50 163
israpafant 27.48 human HepG2 MMP assay decrease Positive IC50 163
kaempferol 6.76 human HepG2 MMP assay decrease Positive IC50 163
kepone 2.82 human HepG2 MMP assay decrease Positive IC50 163
Ketoconazole 5.48 human HepG2 MMP assay decrease Positive IC50 163
lambda-cyhalothrin 15.85 human HepG2 MMP assay decrease Positive IC50 163
lanatoside a 0.14 human HepG2 MMP assay decrease Positive IC50 163
lanatoside b 0.69 human HepG2 MMP assay decrease Positive IC50 163
lanatoside c 0.31 human HepG2 MMP assay decrease Positive IC50 163
lapachol 31.62 human HepG2 MMP assay decrease Positive IC50 163
lasalocid sodium 1.38 human HepG2 MMP assay decrease Positive IC50 163
lercanidipine hydrochloride 8.69 human HepG2 MMP assay decrease Positive IC50 163
lestaurtinib 5.62 human HepG2 MMP assay decrease Positive IC50 163
lornoxicam 6.15 human HepG2 MMP assay decrease Positive IC50 163
lufenuron 14.13 human HepG2 MMP assay decrease Positive IC50 163
lynestrenol 7.4 human HepG2 MMP assay decrease Positive IC50 163
lysergide 17.34 human HepG2 MMP assay decrease Positive IC50 163
malachite green oxalate 27.48 human HepG2 MMP assay decrease Positive IC50 163
malotilate 39.81 human HepG2 MMP assay decrease Positive IC50 163
manidipine 27.48 human HepG2 MMP assay decrease Positive IC50 163
Mebendazole 2.34 human HepG2 MMP assay decrease Positive IC50 163
mepartricin 6.9 human HepG2 MMP assay decrease Positive IC50 163
mepronil 39.81 human HepG2 MMP assay decrease Positive IC50 163
mesotrione 39.81 human HepG2 MMP assay decrease Positive IC50 163
metanixin 21.82 human HepG2 MMP assay decrease Positive IC50 163
methfuroxam 17.78 human HepG2 MMP assay decrease Positive IC50 163
methisazone 12.59 human HepG2 MMP assay decrease Positive IC50 163
Methoxychlor 28.18 human HepG2 MMP assay decrease Positive IC50 163
methyl 2,4-dihydroxy-3,6-dimethylbenzoate 25.12 human HepG2 MMP assay decrease Positive IC50 163
methyl triclosan 39.81 human HepG2 MMP assay decrease Positive IC50 163
methyl violet 0.44 human HepG2 MMP assay decrease Positive IC50 163
methyldigoxin 0.24 human HepG2 MMP assay decrease Positive IC50 163
Methylene Blue 2.75 human HepG2 MMP assay decrease Positive IC50 163
methylene blue trihydrate 4.82 human HepG2 MMP assay decrease Positive IC50 163
methyltrioctylammonium trifluoromethanesulfonate 2.24 human HepG2 MMP assay decrease Positive IC50 163
metochalcone 39.81 human HepG2 MMP assay decrease Positive IC50 163
mgk-264 28.18 human HepG2 MMP assay decrease Positive IC50 163
miripirium chloride 8.69 human HepG2 MMP assay decrease Positive IC50 163
mk-2206 17.34 human HepG2 MMP assay decrease Positive IC50 163
mometasone furoate 8.3 human HepG2 MMP assay decrease Positive IC50 163
n,n-diethylbenzene-1,4-diamine 7.94 human HepG2 MMP assay decrease Positive IC50 163
n,n-dimethyl-p-phenylenediamine 7.08 human HepG2 MMP assay decrease Positive IC50 163
n-benzyl-6-ethoxy-4-oxo-1,4-dihydro-1,5-naphthyridine-3-carboxamide 15.85 human HepG2 MMP assay decrease Positive IC50 163
nelfinavir mesylate 30.83 human HepG2 MMP assay decrease Positive IC50 163
Niclosamide 0.1 human HepG2 MMP assay decrease Positive IC50 163
niflumic acid 15.45 human HepG2 MMP assay decrease Positive IC50 163
nifuroxazide 2.34 human HepG2 MMP assay decrease Positive IC50 163
Nimesulide 4.16 human HepG2 MMP assay decrease Positive IC50 163
ninhydrin 56.23 human HepG2 MMP assay decrease Positive IC50 163
Nitazoxanide 1.26 human HepG2 MMP assay decrease Positive IC50 163
Nitrofurantoin 8.69 human HepG2 MMP assay decrease Positive IC50 163
nitrovin 5.48 human HepG2 MMP assay decrease Positive IC50 163
nitroxoline 19.95 human HepG2 MMP assay decrease Positive IC50 163
n-methyl-n,n-dioctyloctan-1-aminium chloride 10 human HepG2 MMP assay decrease Positive IC50 163
nocodazole 2.18 human HepG2 MMP assay decrease Positive IC50 163
nonylparaben 7.94 human HepG2 MMP assay decrease Positive IC50 163
norelgestromin 19.45 human HepG2 MMP assay decrease Positive IC50 163
noristerat 21.82 human HepG2 MMP assay decrease Positive IC50 163
n-phenyl-1,4-benzenediamine hydrochloride 28.18 human HepG2 MMP assay decrease Positive IC50 163
o,p'-ddd 19.45 human HepG2 MMP assay decrease Positive IC50 163
o,p'-ddt 25.12 human HepG2 MMP assay decrease Positive IC50 163
osalmid 6.31 human HepG2 MMP assay decrease Positive IC50 163
ouabain 0.22 human HepG2 MMP assay decrease Positive IC50 163
oxyphenisatin acetate 17.34 human HepG2 MMP assay decrease Positive IC50 163
p,p'-ddd 39.81 human HepG2 MMP assay decrease Positive IC50 163
p,p'-dde 44.67 human HepG2 MMP assay decrease Positive IC50 163
p,p'-ddt 30.83 human HepG2 MMP assay decrease Positive IC50 163
palmatine chloride hydrate 12.59 human HepG2 MMP assay decrease Positive IC50 163
p-benzoquinone dioxime 25.12 human HepG2 MMP assay decrease Positive IC50 163
penfluridol 27.48 human HepG2 MMP assay decrease Positive IC50 163
2,2',4,4',5-pentabromodiphenyl ether 8.91 human HepG2 MMP assay decrease Positive IC50 163
pentabromophenol 7.94 human HepG2 MMP assay decrease Positive IC50 163
Pentachlorophenol 8.9 human HepG2 MMP assay decrease Positive IC50 163
pentylparaben 14.13 human HepG2 MMP assay decrease Positive IC50 163
perfluorooctanesulfonamide 2.51 human HepG2 MMP assay decrease Positive IC50 163
phenmedipham 7.08 human HepG2 MMP assay decrease Positive IC50 163
phenol, 4,4'-butylidenebis[2-(1,1-dimethylethyl)-5-methyl- 7.08 human HepG2 MMP assay decrease Positive IC50 163
phenol, 4-methyl-, reaction products with dicyclopentadiene and isobutylene 8.69 human HepG2 MMP assay decrease Positive IC50 163
phenolphthalein 25.12 human HepG2 MMP assay decrease Positive IC50 163
phenoxybenzamine hydrochloride 35.48 human HepG2 MMP assay decrease Positive IC50 163
phenyl isothiocyanate 35.48 human HepG2 MMP assay decrease Positive IC50 163
phloretin 11.22 human HepG2 MMP assay decrease Positive IC50 163
picoxystrobin 1 human HepG2 MMP assay decrease Positive IC50 163
picropodophyllin 0.05 human HepG2 MMP assay decrease Positive IC50 163
pinacyanol 0.02 human HepG2 MMP assay decrease Positive IC50 163
pirarubicin 0.69 human HepG2 MMP assay decrease Positive IC50 163
Piroxicam 5.88 human HepG2 MMP assay decrease Positive IC50 163
polyethylene glycol (9z)-9-octadecenyl ether 7.94 human HepG2 MMP assay decrease Positive IC50 163
polyoxyethylene(10)nonylphenyl ether 4.89 human HepG2 MMP assay decrease Positive IC50 163
p-phenylazophenol 10 human HepG2 MMP assay decrease Positive IC50 163
prodiamine 8.91 human HepG2 MMP assay decrease Positive IC50 163
profenofos 6.15 human HepG2 MMP assay decrease Positive IC50 163
proflavin hemisulfate 3.46 human HepG2 MMP assay decrease Positive IC50 163
proflavin hydrochloride 3.55 human HepG2 MMP assay decrease Positive IC50 163
profluralin 39.81 human HepG2 MMP assay decrease Positive IC50 163
propan-2-yl (2r,4s)-4-{acetyl[3,5-bis(trifluoromethyl)benzyl]amino}-2-ethyl-6-(trifluoromethyl)-3,4-dihydroquinoline-1(2h)-carboxylate 4.47 human HepG2 MMP assay decrease Positive IC50 163
propyl gallate 35.48 human HepG2 MMP assay decrease Positive IC50 163
propylparaben 35.48 human HepG2 MMP assay decrease Positive IC50 163
proscillaridin 0.07 human HepG2 MMP assay decrease Positive IC50 163
pyraclostrobin 1.26 human HepG2 MMP assay decrease Positive IC50 163
pyridate 35.48 human HepG2 MMP assay decrease Positive IC50 163
pyrinuron 28.18 human HepG2 MMP assay decrease Positive IC50 163
pyrvinium pamoate 0.17 human HepG2 MMP assay decrease Positive IC50 163
quercetin 3.16 human HepG2 MMP assay decrease Positive IC50 163
quercetin dihydrate 2.95 human HepG2 MMP assay decrease Positive IC50 163
rac benidipine hydrochloride 30.83 human HepG2 MMP assay decrease Positive IC50 163
rafoxanide 1.23 human HepG2 MMP assay decrease Positive IC50 163
raloxifene 17.78 human HepG2 MMP assay decrease Positive IC50 163
raloxifene hydrochloride 7.94 human HepG2 MMP assay decrease Positive IC50 163
resveratrol 3.71 human HepG2 MMP assay decrease Positive IC50 163
Rhein 8.91 human HepG2 MMP assay decrease Positive IC50 163
riboflavin 11.22 human HepG2 MMP assay decrease Positive IC50 163
rifampicin 15.45 human HepG2 MMP assay decrease Positive IC50 163
rifapentine 3.88 human HepG2 MMP assay decrease Positive IC50 163
rimonabant 17.34 human HepG2 MMP assay decrease Positive IC50 163
Rotenone 0.01 human HepG2 MMP assay decrease Positive IC50 163
salicylanilide 3.98 human HepG2 MMP assay decrease Positive IC50 163
siduron 35.48 human HepG2 MMP assay decrease Positive IC50 163
silwet l77 8.91 human HepG2 MMP assay decrease Positive IC50 163
sodium (4-fluoro-2-{[(1s)-1-phenylpropyl]carbamoyl}phenyl)(quinolin-8-ylsulfonyl)azanide 11.22 human HepG2 MMP assay decrease Positive IC50 163
sodium 2-phenylphenate tetrahydrate 31.62 human HepG2 MMP assay decrease Positive IC50 163
sodium bithionolate 0.89 human HepG2 MMP assay decrease Positive IC50 163
sodium warfarin 35.48 human HepG2 MMP assay decrease Positive IC50 163
sofalcone 17.34 human HepG2 MMP assay decrease Positive IC50 163
sorafenib 1.23 human HepG2 MMP assay decrease Positive IC50 163
sp600125 1.55 human HepG2 MMP assay decrease Positive IC50 163
spiperone 3.46 human HepG2 MMP assay decrease Positive IC50 163
su-5416 13.77 human HepG2 MMP assay decrease Positive IC50 163
sulfanitran 17.34 human HepG2 MMP assay decrease Positive IC50 163
surinabant 19.95 human HepG2 MMP assay decrease Positive IC50 163
tamibarotene 13.77 human HepG2 MMP assay decrease Positive IC50 163
tamsulosin hydrochloride 30.83 human HepG2 MMP assay decrease Positive IC50 163
tau-fluvalinate 31.62 human HepG2 MMP assay decrease Positive IC50 163
tenidap 15.85 human HepG2 MMP assay decrease Positive IC50 163
tenonitrozole 0.56 human HepG2 MMP assay decrease Positive IC50 163
tenovin-1 3.88 human HepG2 MMP assay decrease Positive IC50 163
tenoxicam 6.6 human HepG2 MMP assay decrease Positive IC50 163
tert-butyl 4-hydroxybenzoate 35.48 human HepG2 MMP assay decrease Positive IC50 163
tetra-aminopyrimidine sulfate 25.12 human HepG2 MMP assay decrease Positive IC50 163
tetrabromophenolphthalein ethyl ester 26.55 human HepG2 MMP assay decrease Positive IC50 163
tetrabutyltin 11.22 human HepG2 MMP assay decrease Positive IC50 163
tetradecylpyridinium bromide 17.78 human HepG2 MMP assay decrease Positive IC50 163
tetradifon 17.78 human HepG2 MMP assay decrease Positive IC50 163
tetraiodoethene 6.31 human HepG2 MMP assay decrease Positive IC50 163
tetra-n-octylammonium bromide 0.13 human HepG2 MMP assay decrease Positive IC50 163
tetraoctylphosphonium bromide 0.32 human HepG2 MMP assay decrease Positive IC50 163
tetrasul 2.51 human HepG2 MMP assay decrease Positive IC50 163
thidiazuron 6.31 human HepG2 MMP assay decrease Positive IC50 163
thiram 24.49 human HepG2 MMP assay decrease Positive IC50 163
tibrofan 0.87 human HepG2 MMP assay decrease Positive IC50 163
tioxidazole 15.45 human HepG2 MMP assay decrease Positive IC50 163
Tipranavir 17.34 human HepG2 MMP assay decrease Positive IC50 163
tolclofos-methyl 39.81 human HepG2 MMP assay decrease Positive IC50 163
Tolfenamic Acid 17.34 human HepG2 MMP assay decrease Positive IC50 163
toluidine blue 4.89 human HepG2 MMP assay decrease Positive IC50 163
tolvaptan 19.45 human HepG2 MMP assay decrease Positive IC50 163
transfluthrin 19.45 human HepG2 MMP assay decrease Positive IC50 163
tribenoside 11.73 human HepG2 MMP assay decrease Positive IC50 163
tribromosalan 0.97 human HepG2 MMP assay decrease Positive IC50 163
tributyltetradecylphosphonium chloride 1.12 human HepG2 MMP assay decrease Positive IC50 163
tributyltin benzoate 0.5 human HepG2 MMP assay decrease Positive IC50 163
tributyltin chloride 0.89 human HepG2 MMP assay decrease Positive IC50 163
tributyltin methacrylate 0.45 human HepG2 MMP assay decrease Positive IC50 163
tricirbine 0.49 human HepG2 MMP assay decrease Positive IC50 163
triclabendazole 5.48 human HepG2 MMP assay decrease Positive IC50 163
triclocarban 0.17 human HepG2 MMP assay decrease Positive IC50 163
triclosan 6.15 human HepG2 MMP assay decrease Positive IC50 163
triethoxy(2-methylpropyl)silane 35.48 human HepG2 MMP assay decrease Positive IC50 163
triethyltin bromide 0.2 human HepG2 MMP assay decrease Positive IC50 163
trifluralin 39.81 human HepG2 MMP assay decrease Positive IC50 163
trihexyltetradecylphosphonium bromide 0.45 human HepG2 MMP assay decrease Positive IC50 163
trihexyltetradecylphosphonium chloride 0.89 human HepG2 MMP assay decrease Positive IC50 163
trihexyltetradecylphosphonium dicyanamide 0.89 human HepG2 MMP assay decrease Positive IC50 163
trihexyltetradecylphosphonium hexafluorophosphate 1.12 human HepG2 MMP assay decrease Positive IC50 163
triphenyl phosphate 1.26 human HepG2 MMP assay decrease Positive IC50 163
triphenylethylene 31.62 human HepG2 MMP assay decrease Positive IC50 163
triphenyltin acetate 1.12 human HepG2 MMP assay decrease Positive IC50 163
triphenyltin fluoride 1.78 human HepG2 MMP assay decrease Positive IC50 163
triphenyltin hydroxide 1.12 human HepG2 MMP assay decrease Positive IC50 163
tris(2,3-dibromopropyl) phosphate 50.12 human HepG2 MMP assay decrease Positive IC50 163
Tyrothricin 0.24 human HepG2 MMP assay decrease Positive IC50 163
tyrphostin 23 17.34 human HepG2 MMP assay decrease Positive IC50 163
vatalanib 30.83 human HepG2 MMP assay decrease Positive IC50 163
Verteporfin 8.69 human HepG2 MMP assay decrease Positive IC50 163
zafirlukast 13.77 human HepG2 MMP assay decrease Positive IC50 163
zearalenone 5.84 human HepG2 MMP assay decrease Positive IC50 163
(1,1,3,3-tetramethylbutyl)phenol 42.24±3.43 rat hepatocytes MMP assay decrease Positive IC50 163
(1'-ethyl-6,7-dihydro-5h-spiro[furo[2,3-f]indole-3,4'-piperidin]-5-yl)[2'-methyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-yl]methanone hydrochloride 40.87±16.01 rat hepatocytes MMP assay decrease Positive IC50 163
(2-ethyl-4-{[(4-{[4-(4-methoxyphenyl)piperazin-1-yl]methyl}-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl)methyl]sulfanyl}phenoxy)acetic acid 23.10±15.57 rat hepatocytes MMP assay decrease Positive IC50 163
(2-nitro-1-propenyl)benzene 25.94±8.35 rat hepatocytes MMP assay decrease Positive IC50 163
(5-chloro-2-hydroxyphenyl)phenylmethanone 25.43±21.27 rat hepatocytes MMP assay decrease Positive IC50 163
(5s,8s)-5-(3,4-dichlorophenyl)-8-(methylamino)-5,6,7,8-tetrahydronaphthalene-2-sulfonamide 35.72±5.79 rat hepatocytes MMP assay decrease Positive IC50 163
(acryloyloxy)(tributyl)stannane 8.49±2.50 rat hepatocytes MMP assay decrease Positive IC50 163
Diethylstilbestrol 42.80±10.35 rat hepatocytes MMP assay decrease Positive IC50 163
1,1,1-trichloropropanone 23.74±29.59 rat hepatocytes MMP assay decrease Positive IC50 163
1,1,2-trimethyl-1h-benzo[e]indole 34.91±8.48 rat hepatocytes MMP assay decrease Positive IC50 163
1,1':3',1''-terphenyl 29.58±27.73 rat hepatocytes MMP assay decrease Positive IC50 163
1,2,5,6,9,10-hexabromocyclododecane 32.03±16.51 rat hepatocytes MMP assay decrease Positive IC50 163
1,2-phenylenediamine 17.85±6.50 rat hepatocytes MMP assay decrease Positive IC50 163
1,2-phenylenediamine dihydrochloride 14.22±2.30 rat hepatocytes MMP assay decrease Positive IC50 163
1,3,5-tris(4-tert-butyl-3-hydroxy-2,6-dimethylbenzyl)-1,3,5-triazinane-2,4,6-trione 26.79±25.28 rat hepatocytes MMP assay decrease Positive IC50 163
1,3-didecyl-2-methylimidazolium chloride 26.25±3.35 rat hepatocytes MMP assay decrease Positive IC50 163
1,3-diiminobenz(f)isoindoline 26.72±23.58 rat hepatocytes MMP assay decrease Positive IC50 163
1,3-diphenyl-1,3-propanedione 39.83±14.21 rat hepatocytes MMP assay decrease Positive IC50 163
1,4-diaminoanthraquinone 1.24±0.76 rat hepatocytes MMP assay decrease Positive IC50 163
1,4-dihydroxyanthracene-9,10-dione 4.81±8.07 rat hepatocytes MMP assay decrease Positive IC50 163
1,4-naphthalenediamine 22.71±8.75 rat hepatocytes MMP assay decrease Positive IC50 163
1,8-dihydroxy-4,5-dinitroanthraquinone 5.69±2.62 rat hepatocytes MMP assay decrease Positive IC50 163
10-chloro-9-anthraldehyde 24.28±28.84 rat hepatocytes MMP assay decrease Positive IC50 163
Mito-4509 35.48±0.00 rat hepatocytes MMP assay decrease Positive IC50 163
17alpha-ethinylestradiol 18.39±1.50 rat hepatocytes MMP assay decrease Positive IC50 163
1-amino-2,4-dibromoanthraquinone 27.37±4.44 rat hepatocytes MMP assay decrease Positive IC50 163
1-amino-2-methylanthraquinone 5.28±3.30 rat hepatocytes MMP assay decrease Positive IC50 163
1-decyl-3-methylimidazolium tetrafluoroborate 16.76±7.73 rat hepatocytes MMP assay decrease Positive IC50 163
1-decyl-3-methylimidazolium trifluoromethanesulfonate 12.13±3.97 rat hepatocytes MMP assay decrease Positive IC50 163
1-dodecyl-3-methylimidazolium hexafluorophosphate 8.81±2.46 rat hepatocytes MMP assay decrease Positive IC50 163
1-fluoro-2,4-dinitrobenzene 8.30±5.67 rat hepatocytes MMP assay decrease Positive IC50 163
1h-benzo[de]isoquinoline-1,3(2h)-dione 5.56±8.92 rat hepatocytes MMP assay decrease Positive IC50 163
1h-indole-2-carboxamide, n-[(3r)-1-(2-fluorophenyl)-3,4,6,7-tetrahydro-4-oxopyrrolo[3,2,1-jk][1,4]benzodiazepin-3-yl]- 17.34±0.00 rat hepatocytes MMP assay decrease Positive IC50 163
1-hydroxypyrene 33.55±2.73 rat hepatocytes MMP assay decrease Positive IC50 163
1-isocyanato-3-(trifluoromethyl)benzene 11.52±3.69 rat hepatocytes MMP assay decrease Positive IC50 163
1-methyl-3-octylimidazolium hexafluorophosphate 39.81±0.00 rat hepatocytes MMP assay decrease Positive IC50 163
1-methyl-3-octylimidazolium tetrafluoroborate 43.42±7.40 rat hepatocytes MMP assay decrease Positive IC50 163
1-methyl-3-octylimidazolium trifluoromethanesulfonate 31.62±0.00 rat hepatocytes MMP assay decrease Positive IC50 163
1-methylpyrene 32.18±7.36 rat hepatocytes MMP assay decrease Positive IC50 163
1-nitronaphthalene 45.86±14.67 rat hepatocytes MMP assay decrease Positive IC50 163
1-nitropyrene 16.88±4.77 rat hepatocytes MMP assay decrease Positive IC50 163
Edaravone 25.79±10.10 rat hepatocytes MMP assay decrease Positive IC50 163
2-(thiocyanomethylthio)benzothiazole 30.47±26.36 rat hepatocytes MMP assay decrease Positive IC50 163
2,2',4,4',5-pentabromodiphenyl ether 9.11±4.93 rat hepatocytes MMP assay decrease Positive IC50 163
2,2',6,6'-tetrachlorobisphenol a 29.74±11.13 rat hepatocytes MMP assay decrease Positive IC50 163
2,2'4,4'-tetrabromodiphenyl ether 25.56±34.73 rat hepatocytes MMP assay decrease Positive IC50 163
2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane 33.22±24.22 rat hepatocytes MMP assay decrease Positive IC50 163
2,2'-dihydroxy-4,4'-dimethoxybenzophenone 29.81±13.75 rat hepatocytes MMP assay decrease Positive IC50 163
2,2'-dihydroxy-4-methoxybenzophenone 11.08±5.21 rat hepatocytes MMP assay decrease Positive IC50 163
2,2'-methylenebis(4-methyl-6-tert-butylphenol) 3.71±0.47 rat hepatocytes MMP assay decrease Positive IC50 163
2,2'-methylenebis(ethyl-6-tert-butylphenol) 5.01±4.35 rat hepatocytes MMP assay decrease Positive IC50 163
2,3',4,4'-tetrahydroxybenzophenone 40.36±8.45 rat hepatocytes MMP assay decrease Positive IC50 163
2,3,4,5-tetrachlorophenol 11.55±5.42 rat hepatocytes MMP assay decrease Positive IC50 163
2,3,4-trichlorophenol 41.79±14.43 rat hepatocytes MMP assay decrease Positive IC50 163
2,3,5,6-tetrachlorophenol 9.20±2.96 rat hepatocytes MMP assay decrease Positive IC50 163
2,3,5-trichlorophenol 27.65±10.40 rat hepatocytes MMP assay decrease Positive IC50 163
2,4,5-trichlorophenol sodium salt 27.31±25.25 rat hepatocytes MMP assay decrease Positive IC50 163
2,4-bis(1-methyl-1-phenylethyl)phenol 43.93±17.40 rat hepatocytes MMP assay decrease Positive IC50 163
2,4-diaminoanisole sulfate 19.62±19.34 rat hepatocytes MMP assay decrease Positive IC50 163
2,4-di-tert-butylphenol 24.04±16.59 rat hepatocytes MMP assay decrease Positive IC50 163
2,5-bis(2-methylbutan-2-yl)benzene-1,4-diol 34.49±5.88 rat hepatocytes MMP assay decrease Positive IC50 163
2,5-di-tert-butylbenzene-1,4-diol 39.15±15.51 rat hepatocytes MMP assay decrease Positive IC50 163
2,6-diaminopyridine 20.88±15.73 rat hepatocytes MMP assay decrease Positive IC50 163
2,6-di-tert-butyl-4-nitrophenol 0.29±0.30 rat hepatocytes MMP assay decrease Positive IC50 163
2,6-toluenediamine 32.18±7.36 rat hepatocytes MMP assay decrease Positive IC50 163
24r,25-dihydroxyvitamin d3 17.34±0.00 rat hepatocytes MMP assay decrease Positive IC50 163
2-amino-4-(p-nitrophenyl)thiazole 20.55±21.11 rat hepatocytes MMP assay decrease Positive IC50 163
2-amino-4,6-dinitrophenol 28.80±15.58 rat hepatocytes MMP assay decrease Positive IC50 163
2-amino-4-chloro-5-nitrophenol 31.27±8.72 rat hepatocytes MMP assay decrease Positive IC50 163
2-amino-4-chlorobenzothiazole 24.04±16.19 rat hepatocytes MMP assay decrease Positive IC50 163
2-amino-5-nitrophenol 52.13±17.74 rat hepatocytes MMP assay decrease Positive IC50 163
2-amino-6-nitrobenzothiazole 22.74±20.35 rat hepatocytes MMP assay decrease Positive IC50 163
2-aminoanthracene 0.18±0.20 rat hepatocytes MMP assay decrease Positive IC50 163
2-aminoanthraquinone 3.57±2.61 rat hepatocytes MMP assay decrease Positive IC50 163
2-chloro-4-phenylphenol 31.76±3.65 rat hepatocytes MMP assay decrease Positive IC50 163
2-dodecylisoquinolinium tosylate 4.94±2.78 rat hepatocytes MMP assay decrease Positive IC50 163
2-hydrazino-4-(4-aminophenyl) thiazole 3.55±3.86 rat hepatocytes MMP assay decrease Positive IC50 163
2-hydrazino-4-(4-nitrophenyl)thiazole 7.90±5.75 rat hepatocytes MMP assay decrease Positive IC50 163
2-hydrazino-4-phenylthiazole 21.46±17.61 rat hepatocytes MMP assay decrease Positive IC50 163
2-hydroxy-4-methoxybenzophenone 50.14±18.89 rat hepatocytes MMP assay decrease Positive IC50 163
2-hydroxyanthraquinone 17.28±6.83 rat hepatocytes MMP assay decrease Positive IC50 163
2-isovaleryl-1,3-indanedione 22.25±11.09 rat hepatocytes MMP assay decrease Positive IC50 163
2-methyl-1-nitroanthraquinone 16.95±14.73 rat hepatocytes MMP assay decrease Positive IC50 163
2-methylanthraquinone 5.97±0.49 rat hepatocytes MMP assay decrease Positive IC50 163
2-naphthalenol 42.21±19.83 rat hepatocytes MMP assay decrease Positive IC50 163
2-nitro-1,4-phenylenediamine 18.06±14.95 rat hepatocytes MMP assay decrease Positive IC50 163
2-nitrofluorene 38.15±9.22 rat hepatocytes MMP assay decrease Positive IC50 163
2-phenylphenol 53.18±4.32 rat hepatocytes MMP assay decrease Positive IC50 163
2-propenal,3,3-diphenyl- 17.12±23.88 rat hepatocytes MMP assay decrease Positive IC50 163
2-tert-butyl-4-methoxyphenol 36.50±19.25 rat hepatocytes MMP assay decrease Positive IC50 163
2-tert-butyl-5-methylphenol 40.07±6.50 rat hepatocytes MMP assay decrease Positive IC50 163
3,3',4,4'-tetraaminobiphenyl tetrahydrochloride 9.46±4.43 rat hepatocytes MMP assay decrease Positive IC50 163
3,3',5,5'-tetraiodothyroacetic acid 26.13±2.13 rat hepatocytes MMP assay decrease Positive IC50 163
3,3'-diaminobenzidine 30.66±28.30 rat hepatocytes MMP assay decrease Positive IC50 163
3,3'-dimethylbisphenol a 34.35±4.73 rat hepatocytes MMP assay decrease Positive IC50 163
3,3φ,5,5φ-tetrabromobisphenol a 36.91±12.56 rat hepatocytes MMP assay decrease Positive IC50 163
3,4,5-trichlorophenol 33.82±17.20 rat hepatocytes MMP assay decrease Positive IC50 163
3,4-dichlorophenol 53.88±13.03 rat hepatocytes MMP assay decrease Positive IC50 163
3,5-dichlorophenol 46.90±8.44 rat hepatocytes MMP assay decrease Positive IC50 163
3,5-dichlorosalicyl-3,4-dichloroanilide 0.38±0.03 rat hepatocytes MMP assay decrease Positive IC50 163
3-acetylphenanthrene 42.21±19.83 rat hepatocytes MMP assay decrease Positive IC50 163
3-amino-9-ethylcarbazole hydrochloride 56.23±0.00 rat hepatocytes MMP assay decrease Positive IC50 163
3-hydroxy-n-(3-nitrophenyl)naphthalene-2-carboxamide 1.60±0.26 rat hepatocytes MMP assay decrease Positive IC50 163
3-methylbenzene-1,2-diamine 36.64±11.80 rat hepatocytes MMP assay decrease Positive IC50 163
3-methyl-n-phenylaniline 35.48±0.00 rat hepatocytes MMP assay decrease Positive IC50 163
4-(3-phenylpropyl)pyridine 12.95±6.83 rat hepatocytes MMP assay decrease Positive IC50 163
4-(benzyloxyl)phenol 9.04±8.10 rat hepatocytes MMP assay decrease Positive IC50 163
4,4'-diaminoazobenzene 26.63±12.51 rat hepatocytes MMP assay decrease Positive IC50 163
4,4'-diaminobenzanilide 33.55±2.73 rat hepatocytes MMP assay decrease Positive IC50 163
4,4'-dichlorodiphenyl sulfone 29.90±2.43 rat hepatocytes MMP assay decrease Positive IC50 163
4,4'-dinitrodiphenylurea 0.70±0.46 rat hepatocytes MMP assay decrease Positive IC50 163
4,4'-methylenebis(2-chloroaniline) 56.23±0.00 rat hepatocytes MMP assay decrease Positive IC50 163
4,4'-sulfonylbis[2-(prop-2-en-1-yl)phenol] 24.48±19.89 rat hepatocytes MMP assay decrease Positive IC50 163
4,4'-thiobis(6-tert-butyl-m-cresol) 24.82±11.78 rat hepatocytes MMP assay decrease Positive IC50 163
4,4'-thiodiphenol 24.70±9.79 rat hepatocytes MMP assay decrease Positive IC50 163
4,6-dichloro-1,3-benzenediol 35.72±5.79 rat hepatocytes MMP assay decrease Positive IC50 163
4,6-di-tert-butyl-m-cresol 45.86±14.67 rat hepatocytes MMP assay decrease Positive IC50 163
4-amino-2,6-dichlorophenol 29.55±27.78 rat hepatocytes MMP assay decrease Positive IC50 163
4-amino-2-nitrophenol 33.55±2.73 rat hepatocytes MMP assay decrease Positive IC50 163
4-chloro-1,2-diaminobenzene 11.03±4.37 rat hepatocytes MMP assay decrease Positive IC50 163
4-chloro-2-cyclopentylphenol 33.65±29.67 rat hepatocytes MMP assay decrease Positive IC50 163
4-chlorophenyl isocyanate 1.56±0.39 rat hepatocytes MMP assay decrease Positive IC50 163
4-cumylphenol 48.02±11.61 rat hepatocytes MMP assay decrease Positive IC50 163
4-dodecylphenol 25.12±21.80 rat hepatocytes MMP assay decrease Positive IC50 163
4-hexyl-4'-cyanobiphenyl 17.52±15.62 rat hepatocytes MMP assay decrease Positive IC50 163
4-hydroxybenzophenone 17.79±28.01 rat hepatocytes MMP assay decrease Positive IC50 163
4-methyl-2,6-dinitrophenol 15.14±6.79 rat hepatocytes MMP assay decrease Positive IC50 163
4-nitro-n-phenylaniline 23.93±7.05 rat hepatocytes MMP assay decrease Positive IC50 163
4-octyloxybenzoic acid 48.02±11.61 rat hepatocytes MMP assay decrease Positive IC50 163
4-octylphenol 53.18±4.32 rat hepatocytes MMP assay decrease Positive IC50 163
5hpp-33 29.09±12.18 rat hepatocytes MMP assay decrease Positive IC50 163
Busulfan 6.15±3.62 rat hepatocytes MMP assay decrease Positive IC50 163
5-nitroacenaphthene 24.04±16.19 rat hepatocytes MMP assay decrease Positive IC50 163
6-hydroxy-2-naphthyl disulfide 39.81±0.00 rat hepatocytes MMP assay decrease Positive IC50 163
6-nitroquinoline 44.84±16.33 rat hepatocytes MMP assay decrease Positive IC50 163
9,10-dihydrobenzo[a]pyren-7(8h)-one 16.82±7.33 rat hepatocytes MMP assay decrease Positive IC50 163
9-aminoacridine, monohydrochloride, monohydrate 8.51±5.35 rat hepatocytes MMP assay decrease Positive IC50 163
9-anthracenemethanol 21.66±15.72 rat hepatocytes MMP assay decrease Positive IC50 163
9-cyanoanthracene 17.99±5.46 rat hepatocytes MMP assay decrease Positive IC50 163
9-nitroanthracene 33.05±4.21 rat hepatocytes MMP assay decrease Positive IC50 163
9-phenanthrol 47.28±10.66 rat hepatocytes MMP assay decrease Positive IC50 163
acenocoumarol 4.59±1.82 rat hepatocytes MMP assay decrease Positive IC50 163
acetaldehyde 6.65±4.48 rat hepatocytes MMP assay decrease Positive IC50 163
aclarubicin hydrochloride 6.89±9.73 rat hepatocytes MMP assay decrease Positive IC50 163
acriflavine hydrochloride 3.55±1.14 rat hepatocytes MMP assay decrease Positive IC50 163
Albendazole 15.46±21.73 rat hepatocytes MMP assay decrease Positive IC50 163
alizarin 11.87±7.79 rat hepatocytes MMP assay decrease Positive IC50 163
aloe-emodin 8.43±5.96 rat hepatocytes MMP assay decrease Positive IC50 163
alpha-1,2,3,4,5,6-hexachlorocyclohexane 39.81±0.00 rat hepatocytes MMP assay decrease Positive IC50 163
alpha-amylcinnamyl alcohol 4.83±4.07 rat hepatocytes MMP assay decrease Positive IC50 163
ambazone 1.98±2.22 rat hepatocytes MMP assay decrease Positive IC50 163
ami-193 25.96±12.20 rat hepatocytes MMP assay decrease Positive IC50 163
amsacrine hydrochloride 37.65±3.06 rat hepatocytes MMP assay decrease Positive IC50 163
anthrone 42.40±11.98 rat hepatocytes MMP assay decrease Positive IC50 163
apigenin 28.93±9.26 rat hepatocytes MMP assay decrease Positive IC50 163
barban 35.97±7.53 rat hepatocytes MMP assay decrease Positive IC50 163
bardoxolone methyl 17.41±2.00 rat hepatocytes MMP assay decrease Positive IC50 163
basic blue 7 1.53±1.42 rat hepatocytes MMP assay decrease Positive IC50 163
beclazone 16.28±20.57 rat hepatocytes MMP assay decrease Positive IC50 163
benzbromarone 4.91±1.79 rat hepatocytes MMP assay decrease Positive IC50 163
benzidine 2.51±3.54 rat hepatocytes MMP assay decrease Positive IC50 163
benziodarone 1.76±0.68 rat hepatocytes MMP assay decrease Positive IC50 163
benzoic acid, 2-[(4-chloro-3-methylphenyl)amino]- 22.71±16.22 rat hepatocytes MMP assay decrease Positive IC50 163
benzyldodecyldimethylammonium bromide 18.39±1.50 rat hepatocytes MMP assay decrease Positive IC50 163
berberine chloride 6.03±3.78 rat hepatocytes MMP assay decrease Positive IC50 163
bexarotene 9.08±1.16 rat hepatocytes MMP assay decrease Positive IC50 163
bisacodyl 18.39±13.00 rat hepatocytes MMP assay decrease Positive IC50 163
Bisphenol A 37.65±3.06 rat hepatocytes MMP assay decrease Positive IC50 163
bisphenol a glycidyl methacrylate 38.15±9.22 rat hepatocytes MMP assay decrease Positive IC50 163
bisphenol af 37.26±6.70 rat hepatocytes MMP assay decrease Positive IC50 163
bisphenol b 21.75±8.60 rat hepatocytes MMP assay decrease Positive IC50 163
bisphenol e 36.50±19.25 rat hepatocytes MMP assay decrease Positive IC50 163
bisphenol z 14.71±15.12 rat hepatocytes MMP assay decrease Positive IC50 163
bithionol 2.47±1.39 rat hepatocytes MMP assay decrease Positive IC50 163
bosutinib 16.59±11.17 rat hepatocytes MMP assay decrease Positive IC50 163
bromadiolone 3.40±0.83 rat hepatocytes MMP assay decrease Positive IC50 163
bromocriptine 13.20±10.83 rat hepatocytes MMP assay decrease Positive IC50 163
bromocriptine mesylate 12.57±1.60 rat hepatocytes MMP assay decrease Positive IC50 163
bromofenoxim 2.18±0.86 rat hepatocytes MMP assay decrease Positive IC50 163
bromofos 22.65±10.42 rat hepatocytes MMP assay decrease Positive IC50 163
bromoxynil octanoate 28.63±22.68 rat hepatocytes MMP assay decrease Positive IC50 163
broquinaldol 38.61±34.63 rat hepatocytes MMP assay decrease Positive IC50 163
bryostatin 1 0.79±1.07 rat hepatocytes MMP assay decrease Positive IC50 163
c.i. 1040 19.72±4.13 rat hepatocytes MMP assay decrease Positive IC50 163
c.i. basic orange 2 24.91±21.08 rat hepatocytes MMP assay decrease Positive IC50 163
c.i. basic red 9 monohydrochloride 4.11±4.24 rat hepatocytes MMP assay decrease Positive IC50 163
c.i. basic violet 14 6.84±4.71 rat hepatocytes MMP assay decrease Positive IC50 163
c.i. disperse blue 27 32.46±10.39 rat hepatocytes MMP assay decrease Positive IC50 163
c.i. solvent yellow 14 17.04±10.60 rat hepatocytes MMP assay decrease Positive IC50 163
calcifediol 14.21±9.57 rat hepatocytes MMP assay decrease Positive IC50 163
calcipotriene 17.34±0.00 rat hepatocytes MMP assay decrease Positive IC50 163
calcitriol 22.41±7.17 rat hepatocytes MMP assay decrease Positive IC50 163
cannabinol 21.82±0.00 rat hepatocytes MMP assay decrease Positive IC50 163
cantharidin 0.45±0.30 rat hepatocytes MMP assay decrease Positive IC50 163
chlorfenapyr 0.07±0.01 rat hepatocytes MMP assay decrease Positive IC50 163
chlorfenethol 18.94±5.35 rat hepatocytes MMP assay decrease Positive IC50 163
chlorfenson 23.70±17.18 rat hepatocytes MMP assay decrease Positive IC50 163
chlorfluazuron 29.33±1.99 rat hepatocytes MMP assay decrease Positive IC50 163
chlorophacinone 4.65±4.78 rat hepatocytes MMP assay decrease Positive IC50 163
chloropropylate 43.84±10.95 rat hepatocytes MMP assay decrease Positive IC50 163
chrysarobin 19.29±8.27 rat hepatocytes MMP assay decrease Positive IC50 163
chrysin 30.60±28.39 rat hepatocytes MMP assay decrease Positive IC50 163
Ciglitazone 9.92±4.25 rat hepatocytes MMP assay decrease Positive IC50 163
cilnidipine 14.79±8.07 rat hepatocytes MMP assay decrease Positive IC50 163
cinalukast 13.54±5.36 rat hepatocytes MMP assay decrease Positive IC50 163
clobetasol 19.76±15.65 rat hepatocytes MMP assay decrease Positive IC50 163
clobetasol propionate 24.08±9.54 rat hepatocytes MMP assay decrease Positive IC50 163
cloflucarban 0.58±0.05 rat hepatocytes MMP assay decrease Positive IC50 163
clofoctol 15.67±6.04 rat hepatocytes MMP assay decrease Positive IC50 163
clonixin 18.31±5.10 rat hepatocytes MMP assay decrease Positive IC50 163
coumatetralyl 13.76±8.10 rat hepatocytes MMP assay decrease Positive IC50 163
cresyl diphenyl phosphate 22.99±9.00 rat hepatocytes MMP assay decrease Positive IC50 163
curcumin 11.60±9.87 rat hepatocytes MMP assay decrease Positive IC50 163
cybutryne 14.30±16.00 rat hepatocytes MMP assay decrease Positive IC50 163
cyhalothrin 33.80±9.96 rat hepatocytes MMP assay decrease Positive IC50 163
danthron 5.97±5.35 rat hepatocytes MMP assay decrease Positive IC50 163
dantrolene sodium 15.52±1.78 rat hepatocytes MMP assay decrease Positive IC50 163
darbufelone mesylate 7.15±5.41 rat hepatocytes MMP assay decrease Positive IC50 163
deltamethrin 39.83±14.21 rat hepatocytes MMP assay decrease Positive IC50 163
devazepide 15.63±7.19 rat hepatocytes MMP assay decrease Positive IC50 163
dexamethasone valerate 23.46±5.67 rat hepatocytes MMP assay decrease Positive IC50 163
diacerein 14.17±11.27 rat hepatocytes MMP assay decrease Positive IC50 163
dibutyltin dilaurate 22.41±7.17 rat hepatocytes MMP assay decrease Positive IC50 163
dichlofluanid 22.96±29.49 rat hepatocytes MMP assay decrease Positive IC50 163
diclazuril 5.70±1.94 rat hepatocytes MMP assay decrease Positive IC50 163
dicofol 24.64±9.27 rat hepatocytes MMP assay decrease Positive IC50 163
Diethylstilbestrol 25.19±21.68 rat hepatocytes MMP assay decrease Positive IC50 163
diethylstilbestrol dipropionate 49.29±19.53 rat hepatocytes MMP assay decrease Positive IC50 163
dinex 1.40±0.60 rat hepatocytes MMP assay decrease Positive IC50 163
diniconazole 36.04±28.56 rat hepatocytes MMP assay decrease Positive IC50 163
dinobuton 5.74±4.21 rat hepatocytes MMP assay decrease Positive IC50 163
dinocap 4.10±2.16 rat hepatocytes MMP assay decrease Positive IC50 163
dinoterb 0.76±0.45 rat hepatocytes MMP assay decrease Positive IC50 163
diphenan 84.22±39.58 rat hepatocytes MMP assay decrease Positive IC50 163
diphenoxylate hydrochloride 19.45±0.00 rat hepatocytes MMP assay decrease Positive IC50 163
diphenylurea 8.46±2.39 rat hepatocytes MMP assay decrease Positive IC50 163
disperse red 82 11.68±8.76 rat hepatocytes MMP assay decrease Positive IC50 163
dithiazanine chloride 2.45±0.00 rat hepatocytes MMP assay decrease Positive IC50 163
dithiazanine iodide 0.98±0.16 rat hepatocytes MMP assay decrease Positive IC50 163
docetaxel 12.07±4.78 rat hepatocytes MMP assay decrease Positive IC50 163
dodecyl gallate 48.72±8.30 rat hepatocytes MMP assay decrease Positive IC50 163
dodecylphenol 41.11±13.24 rat hepatocytes MMP assay decrease Positive IC50 163
doramapimod;bibr-796? 24.08±9.54 rat hepatocytes MMP assay decrease Positive IC50 163
ebselen 21.42±5.35 rat hepatocytes MMP assay decrease Positive IC50 163
emodin 6.28±4.57 rat hepatocytes MMP assay decrease Positive IC50 163
endosulfan sulfate 25.80±10.10 rat hepatocytes MMP assay decrease Positive IC50 163
eprinomectin (b1a, b1b mixture) 8.28±2.44 rat hepatocytes MMP assay decrease Positive IC50 163
equilin 39.15±15.51 rat hepatocytes MMP assay decrease Positive IC50 163
ethacridine lactate hydrate 10.25±5.58 rat hepatocytes MMP assay decrease Positive IC50 163
ethanol, 2,2'-((1-methylethylidene)bis((2,6-dibromo-4,1-phenylene)oxy))bis- 32.82±2.67 rat hepatocytes MMP assay decrease Positive IC50 163
ethoxazene 4.96±3.42 rat hepatocytes MMP assay decrease Positive IC50 163
etocarlide 27.65±10.40 rat hepatocytes MMP assay decrease Positive IC50 163
everolimus 13.01±7.49 rat hepatocytes MMP assay decrease Positive IC50 163
exalamide 29.15±2.37 rat hepatocytes MMP assay decrease Positive IC50 163
ezetimibe 16.64±20.07 rat hepatocytes MMP assay decrease Positive IC50 163
famoxadone 8.38±6.71 rat hepatocytes MMP assay decrease Positive IC50 163
fenamidone 42.80±10.35 rat hepatocytes MMP assay decrease Positive IC50 163
fenarimol 33.55±2.73 rat hepatocytes MMP assay decrease Positive IC50 163
fenchlorphos 20.64±1.68 rat hepatocytes MMP assay decrease Positive IC50 163
fenhexamid 36.72±21.22 rat hepatocytes MMP assay decrease Positive IC50 163
fentiazac 9.49±7.98 rat hepatocytes MMP assay decrease Positive IC50 163
fenticlor 13.88±8.84 rat hepatocytes MMP assay decrease Positive IC50 163
fluazuron 9.83±13.60 rat hepatocytes MMP assay decrease Positive IC50 163
flubendiamide 12.80±8.15 rat hepatocytes MMP assay decrease Positive IC50 163
flucythrinate 43.93±17.40 rat hepatocytes MMP assay decrease Positive IC50 163
Flufenamic Acid 14.45±4.99 rat hepatocytes MMP assay decrease Positive IC50 163
flunixin meglumine 5.77±4.59 rat hepatocytes MMP assay decrease Positive IC50 163
fluorodifen 24.07±14.98 rat hepatocytes MMP assay decrease Positive IC50 163
fluorosalan 0.42±0.48 rat hepatocytes MMP assay decrease Positive IC50 163
fluoxastrobin 37.94±19.29 rat hepatocytes MMP assay decrease Positive IC50 163
folpet 33.72±20.15 rat hepatocytes MMP assay decrease Positive IC50 163
forchlorfenuron 2.19±1.97 rat hepatocytes MMP assay decrease Positive IC50 163
formononetin 13.20±16.25 rat hepatocytes MMP assay decrease Positive IC50 163
fulvestrant 8.84±12.01 rat hepatocytes MMP assay decrease Positive IC50 163
geliomycin 0.55±0.31 rat hepatocytes MMP assay decrease Positive IC50 163
genistein 33.67±19.54 rat hepatocytes MMP assay decrease Positive IC50 163
gentian violet 1.34±0.11 rat hepatocytes MMP assay decrease Positive IC50 163
glycyrrhetinic acid 15.55±2.52 rat hepatocytes MMP assay decrease Positive IC50 163
gramicidin 0.20±0.21 rat hepatocytes MMP assay decrease Positive IC50 163
halobetasol propionate 25.21±7.02 rat hepatocytes MMP assay decrease Positive IC50 163
Hexachlorophene 1.00±0.74 rat hepatocytes MMP assay decrease Positive IC50 163
hydroxystilbamidine bis(methanesulfonate) 13.60±8.28 rat hepatocytes MMP assay decrease Positive IC50 163
idarubicin hydrochloride 27.02±10.70 rat hepatocytes MMP assay decrease Positive IC50 163
indole-3-pyruvic acid 21.29±17.89 rat hepatocytes MMP assay decrease Positive IC50 163
indoxacarb 34.42±5.58 rat hepatocytes MMP assay decrease Positive IC50 163
iodophthalein 7.32±0.60 rat hepatocytes MMP assay decrease Positive IC50 163
iodophthalein sodium 8.73±1.00 rat hepatocytes MMP assay decrease Positive IC50 163
isoxicam 4.92±0.80 rat hepatocytes MMP assay decrease Positive IC50 163
israpafant 23.46±5.67 rat hepatocytes MMP assay decrease Positive IC50 163
kaempferol 24.06±8.76 rat hepatocytes MMP assay decrease Positive IC50 163
kepone 10.15±9.25 rat hepatocytes MMP assay decrease Positive IC50 163
lambda-cyhalothrin 28.18±0.00 rat hepatocytes MMP assay decrease Positive IC50 163
lasalocid sodium 1.30±0.29 rat hepatocytes MMP assay decrease Positive IC50 163
lercanidipine hydrochloride 27.48±0.00 rat hepatocytes MMP assay decrease Positive IC50 163
lestaurtinib 12.76±2.67 rat hepatocytes MMP assay decrease Positive IC50 163
lopinavir 15.42±21.79 rat hepatocytes MMP assay decrease Positive IC50 163
lornoxicam 3.30±2.52 rat hepatocytes MMP assay decrease Positive IC50 163
lufenuron 44.96±7.29 rat hepatocytes MMP assay decrease Positive IC50 163
malachite green oxalate 8.67±12.26 rat hepatocytes MMP assay decrease Positive IC50 163
malotilate 23.92±29.35 rat hepatocytes MMP assay decrease Positive IC50 163
manidipine 20.91±5.06 rat hepatocytes MMP assay decrease Positive IC50 163
mepartricin 27.66±4.48 rat hepatocytes MMP assay decrease Positive IC50 163
mepronil 56.23±0.00 rat hepatocytes MMP assay decrease Positive IC50 163
metanixin 21.03±1.37 rat hepatocytes MMP assay decrease Positive IC50 163
methisazone 21.51±9.04 rat hepatocytes MMP assay decrease Positive IC50 163
Methoxychlor 27.72±10.98 rat hepatocytes MMP assay decrease Positive IC50 163
methyl 2,4-dihydroxy-3,6-dimethylbenzoate 30.57±28.43 rat hepatocytes MMP assay decrease Positive IC50 163
methyl triclosan 45.86±14.67 rat hepatocytes MMP assay decrease Positive IC50 163
methyl violet 1.73±0.00 rat hepatocytes MMP assay decrease Positive IC50 163
methylene blue trihydrate 7.29±7.49 rat hepatocytes MMP assay decrease Positive IC50 163
methyltrioctylammonium trifluoromethanesulfonate 11.36±2.12 rat hepatocytes MMP assay decrease Positive IC50 163
metochalcone 25.48±18.19 rat hepatocytes MMP assay decrease Positive IC50 163
mgk-264 17.77±25.05 rat hepatocytes MMP assay decrease Positive IC50 163
miripirium chloride 19.54±2.25 rat hepatocytes MMP assay decrease Positive IC50 163
mometasone furoate 13.96±1.14 rat hepatocytes MMP assay decrease Positive IC50 163
montelukast sodium 24.08±9.54 rat hepatocytes MMP assay decrease Positive IC50 163
n,n-diethylbenzene-1,4-diamine 31.62±0.00 rat hepatocytes MMP assay decrease Positive IC50 163
n,n-dimethyl-p-phenylenediamine 21.66±15.72 rat hepatocytes MMP assay decrease Positive IC50 163
n,nφ-diethylcarbanilide 13.11±16.35 rat hepatocytes MMP assay decrease Positive IC50 163
n-benzyl-6-ethoxy-4-oxo-1,4-dihydro-1,5-naphthyridine-3-carboxamide 24.04±16.59 rat hepatocytes MMP assay decrease Positive IC50 163
n-cyclohexyl-4-methyl benzenesulfonamide 38.09±25.65 rat hepatocytes MMP assay decrease Positive IC50 163
nelfinavir mesylate 8.68±12.24 rat hepatocytes MMP assay decrease Positive IC50 163
Niclosamide 0.44±0.27 rat hepatocytes MMP assay decrease Positive IC50 163
niflumic acid 6.71±1.14 rat hepatocytes MMP assay decrease Positive IC50 163
nifuroxazide 6.71±1.54 rat hepatocytes MMP assay decrease Positive IC50 163
Nimesulide 2.74±0.35 rat hepatocytes MMP assay decrease Positive IC50 163
Nitazoxanide 6.94±4.36 rat hepatocytes MMP assay decrease Positive IC50 163
Nitrofurantoin 7.26±6.35 rat hepatocytes MMP assay decrease Positive IC50 163
nitrovin 16.39±1.33 rat hepatocytes MMP assay decrease Positive IC50 163
nitroxoline 72.33±39.13 rat hepatocytes MMP assay decrease Positive IC50 163
n-methyl-n,n-dioctyloctan-1-aminium chloride 19.58±4.89 rat hepatocytes MMP assay decrease Positive IC50 163
n-nitroso-n-methyl-4-nitroaniline 20.04±16.60 rat hepatocytes MMP assay decrease Positive IC50 163
norelgestromin 13.37±12.30 rat hepatocytes MMP assay decrease Positive IC50 163
o,p'-ddd 24.18±14.72 rat hepatocytes MMP assay decrease Positive IC50 163
osalmid 30.03±21.28 rat hepatocytes MMP assay decrease Positive IC50 163
oxyphenisatin acetate 20.64±1.68 rat hepatocytes MMP assay decrease Positive IC50 163
p,p'-ddd 42.21±19.83 rat hepatocytes MMP assay decrease Positive IC50 163
palmatine chloride hydrate 1.37±0.70 rat hepatocytes MMP assay decrease Positive IC50 163
penfluridol 23.24±6.57 rat hepatocytes MMP assay decrease Positive IC50 163
2,2',4,4',5-pentabromodiphenyl ether 32.91±2.23 rat hepatocytes MMP assay decrease Positive IC50 163
pentabromophenol 4.98±2.48 rat hepatocytes MMP assay decrease Positive IC50 163
Pentachlorophenol 4.17±0.75 rat hepatocytes MMP assay decrease Positive IC50 163
perfluorooctanesulfonamide 1.47±0.10 rat hepatocytes MMP assay decrease Positive IC50 163
phenazopyridine hydrochloride 23.75±1.93 rat hepatocytes MMP assay decrease Positive IC50 163
phenmedipham 19.38±9.11 rat hepatocytes MMP assay decrease Positive IC50 163
phenol, 4,4'-butylidenebis[2-(1,1-dimethylethyl)-5-methyl- 21.10±18.22 rat hepatocytes MMP assay decrease Positive IC50 163
phenol, 4-methyl-, reaction products with dicyclopentadiene and isobutylene 0.11±0.07 rat hepatocytes MMP assay decrease Positive IC50 163
phenolphthalein 39.48±16.93 rat hepatocytes MMP assay decrease Positive IC50 163
phloretin 10.60±4.98 rat hepatocytes MMP assay decrease Positive IC50 163
picoxystrobin 14.60±4.70 rat hepatocytes MMP assay decrease Positive IC50 163
pinacyanol 0.04±0.01 rat hepatocytes MMP assay decrease Positive IC50 163
pioglitazone hydrochloride 8.90±9.20 rat hepatocytes MMP assay decrease Positive IC50 163
pirarubicin 0.03±0.00 rat hepatocytes MMP assay decrease Positive IC50 163
Piroxicam 4.79±1.53 rat hepatocytes MMP assay decrease Positive IC50 163
polyethylene glycol (9z)-9-octadecenyl ether 40.87±13.08 rat hepatocytes MMP assay decrease Positive IC50 163
prodiamine 25.42±11.69 rat hepatocytes MMP assay decrease Positive IC50 163
profenofos 13.19±3.19 rat hepatocytes MMP assay decrease Positive IC50 163
proflavin hemisulfate 11.60±5.45 rat hepatocytes MMP assay decrease Positive IC50 163
proflavin hydrochloride 15.91±5.23 rat hepatocytes MMP assay decrease Positive IC50 163
profluralin 25.06±35.43 rat hepatocytes MMP assay decrease Positive IC50 163
pyraclostrobin 9.04±1.89 rat hepatocytes MMP assay decrease Positive IC50 163
pyridate 50.45±8.18 rat hepatocytes MMP assay decrease Positive IC50 163
pyrinuron 25.79±10.10 rat hepatocytes MMP assay decrease Positive IC50 163
pyrvinium pamoate 1.03±0.26 rat hepatocytes MMP assay decrease Positive IC50 163
quercetin 15.14±6.79 rat hepatocytes MMP assay decrease Positive IC50 163
quercetin dihydrate 5.83±4.93 rat hepatocytes MMP assay decrease Positive IC50 163
rafoxanide 1.86±0.83 rat hepatocytes MMP assay decrease Positive IC50 163
raloxifene 22.40±24.05 rat hepatocytes MMP assay decrease Positive IC50 163
raloxifene hydrochloride 20.94±7.23 rat hepatocytes MMP assay decrease Positive IC50 163
Rhein 11.58±4.85 rat hepatocytes MMP assay decrease Positive IC50 163
riboflavin 31.27±8.72 rat hepatocytes MMP assay decrease Positive IC50 163
rifampicin 6.15±2.20 rat hepatocytes MMP assay decrease Positive IC50 163
rifapentine 0.62±0.55 rat hepatocytes MMP assay decrease Positive IC50 163
rimonabant 17.45±2.83 rat hepatocytes MMP assay decrease Positive IC50 163
Rotenone 0.20±0.30 rat hepatocytes MMP assay decrease Positive IC50 163
salicylanilide 29.09±12.18 rat hepatocytes MMP assay decrease Positive IC50 163
selenious acid 44.11±26.85 rat hepatocytes MMP assay decrease Positive IC50 163
siduron 43.93±17.40 rat hepatocytes MMP assay decrease Positive IC50 163
silwet l77 14.31±2.67 rat hepatocytes MMP assay decrease Positive IC50 163
rapamycin 20.64±1.68 rat hepatocytes MMP assay decrease Positive IC50 163
sodium (4-fluoro-2-{[(1s)-1-phenylpropyl]carbamoyl}phenyl)(quinolin-8-ylsulfonyl)azanide 35.85±20.20 rat hepatocytes MMP assay decrease Positive IC50 163
sodium warfarin 35.48±0.00 rat hepatocytes MMP assay decrease Positive IC50 163
sofalcone 19.54±2.25 rat hepatocytes MMP assay decrease Positive IC50 163
sorafenib 2.25±0.63 rat hepatocytes MMP assay decrease Positive IC50 163
sp600125 21.13±2.91 rat hepatocytes MMP assay decrease Positive IC50 163
spiperone 2.92±0.24 rat hepatocytes MMP assay decrease Positive IC50 163
su-5416 11.01±1.78 rat hepatocytes MMP assay decrease Positive IC50 163
sulfanitran 19.54±2.25 rat hepatocytes MMP assay decrease Positive IC50 163
surinabant 34.31±22.53 rat hepatocytes MMP assay decrease Positive IC50 163
talniflumate 15.95±6.68 rat hepatocytes MMP assay decrease Positive IC50 163
tamibarotene 9.06±6.66 rat hepatocytes MMP assay decrease Positive IC50 163
tamsulosin hydrochloride 25.14±8.04 rat hepatocytes MMP assay decrease Positive IC50 163
tenidap 21.05±7.88 rat hepatocytes MMP assay decrease Positive IC50 163
tenonitrozole 0.68±0.45 rat hepatocytes MMP assay decrease Positive IC50 163
tenovin-1 18.39±1.50 rat hepatocytes MMP assay decrease Positive IC50 163
tenoxicam 4.23±3.79 rat hepatocytes MMP assay decrease Positive IC50 163
tert-butyl 4-hydroxybenzoate 50.76±9.48 rat hepatocytes MMP assay decrease Positive IC50 163
tetra-aminopyrimidine sulfate 42.14±30.55 rat hepatocytes MMP assay decrease Positive IC50 163
tetrabromophenolphthalein ethyl ester 13.85±0.94 rat hepatocytes MMP assay decrease Positive IC50 163
tetrabutylphosphonium chloride 15.30±5.00 rat hepatocytes MMP assay decrease Positive IC50 163
tetradecylpyridinium bromide 33.55±2.73 rat hepatocytes MMP assay decrease Positive IC50 163
tetradifon 12.05±6.57 rat hepatocytes MMP assay decrease Positive IC50 163
tetraiodoethene 22.56±14.37 rat hepatocytes MMP assay decrease Positive IC50 163
tetraoctylphosphonium bromide 6.82±2.23 rat hepatocytes MMP assay decrease Positive IC50 163
thidiazuron 4.56±2.78 rat hepatocytes MMP assay decrease Positive IC50 163
thiram 16.51±20.26 rat hepatocytes MMP assay decrease Positive IC50 163
tibrofan 16.96±6.90 rat hepatocytes MMP assay decrease Positive IC50 163
tioxidazole 13.02±1.06 rat hepatocytes MMP assay decrease Positive IC50 163
Tipranavir 29.15±2.37 rat hepatocytes MMP assay decrease Positive IC50 163
tolclofos-methyl 31.23±19.01 rat hepatocytes MMP assay decrease Positive IC50 163
Tolfenamic Acid 14.81±4.38 rat hepatocytes MMP assay decrease Positive IC50 163
tolvaptan 17.41±2.00 rat hepatocytes MMP assay decrease Positive IC50 163
tribromosalan 0.55±0.36 rat hepatocytes MMP assay decrease Positive IC50 163
tributyltetradecylphosphonium chloride 7.66±0.50 rat hepatocytes MMP assay decrease Positive IC50 163
tributyltin benzoate 5.33±4.70 rat hepatocytes MMP assay decrease Positive IC50 163
tributyltin chloride 8.95±1.03 rat hepatocytes MMP assay decrease Positive IC50 163
tributyltin methacrylate 12.76±2.67 rat hepatocytes MMP assay decrease Positive IC50 163
triclabendazole 15.55±2.52 rat hepatocytes MMP assay decrease Positive IC50 163
triclocarban 0.17±0.10 rat hepatocytes MMP assay decrease Positive IC50 163
triclosan 15.17±13.52 rat hepatocytes MMP assay decrease Positive IC50 163
triethyltin bromide 0.56±0.21 rat hepatocytes MMP assay decrease Positive IC50 163
trifluralin 32.62±23.13 rat hepatocytes MMP assay decrease Positive IC50 163
trihexyltetradecylphosphonium bromide 18.82±4.25 rat hepatocytes MMP assay decrease Positive IC50 163
trihexyltetradecylphosphonium chloride 30.31±8.97 rat hepatocytes MMP assay decrease Positive IC50 163
trihexyltetradecylphosphonium dicyanamide 31.02±11.67 rat hepatocytes MMP assay decrease Positive IC50 163
triphenyl phosphate 28.93±9.26 rat hepatocytes MMP assay decrease Positive IC50 163
triphenylethylene 15.24±11.48 rat hepatocytes MMP assay decrease Positive IC50 163
triphenyltin acetate 24.13±10.14 rat hepatocytes MMP assay decrease Positive IC50 163
triphenyltin fluoride 6.17±2.51 rat hepatocytes MMP assay decrease Positive IC50 163
triphenyltin hydroxide 14.83±5.12 rat hepatocytes MMP assay decrease Positive IC50 163
tris(2,3-dibromopropyl) phosphate 43.95±10.68 rat hepatocytes MMP assay decrease Positive IC50 163
Tyrothricin 0.66±0.39 rat hepatocytes MMP assay decrease Positive IC50 163
vatalanib 20.73±14.69 rat hepatocytes MMP assay decrease Positive IC50 163
Verteporfin 21.83±7.79 rat hepatocytes MMP assay decrease Positive IC50 163
zafirlukast 3.43±1.47 rat hepatocytes MMP assay decrease Positive IC50 163
zearalenone 21.97±1.79 rat hepatocytes MMP assay decrease Positive IC50 163
glyceraldehyde 3-phosphate 2.5mM decrease Positive 162
dihydroxyacetone phosphate decrease Positive 162
Clofarabine Positive 284
Acetaminophen > 200 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Acetylsalicylic acid 335.5 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
alpidem 83.7 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Amantadine 261.2 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Ambroxol > 200 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Amiodarone 2.6 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Amoxicillin > 400 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Ampicillin > 400 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Antipyrine 300 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Arsenic trioxide 237.9 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Biotin 4.3 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
lumiracoxib > 400 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
bisacodyl 312.4 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
estradiol acetate > 200 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Bupivacaine 258.2 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Busulfan 483.1 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Butein > 200 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Caffeine > 400 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Capsaicin 275 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Carbamazepine 66.9 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Cefixime > 400 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Chlorambucil > 200 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Ciprofloxacin > 400 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Clodronate > 400 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Clotrimazole 23.9 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
curcumin > 200 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
dexamethasone valerate > 200 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Diazoxide > 200 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Diclofenac 137.9 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Diflunisal 17.9 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Doxorubicin 8.9 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
erlotinib 195.9 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Fluconazole 512.7 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Flufenamic Acid 42.5 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Flutamide 27 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
gefitinib 9.6 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
genistein 150.6 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Glimepiride 94.6 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Gossypol 1 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Ibuprofen 355.9 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Imatinib 25.7 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
imipramine 74.8 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Indomethacin 443.2 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Isoniazid 504.6 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Ketoconazole 243 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Lamivudine 347.2 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Lidocaine 339.5 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Lonidamine 138.1 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
lovastatin 43.6 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
lumiracoxib 148.8 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Manganese > 800 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Mefenamic acid 49.7 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Metformin 388.4 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Mitomycin > 200 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Mitoxantrone 7 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Nicotine > 400 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
nifuroxazide 388.2 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Nimesulide 10.1 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Nitrofurantoin 442.5 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Perhexiline 3.2 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Piroxicam 101.7 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
pravastatin > 200 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
propylparaben 162.8 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Pyrazinamide > 400 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
resveratrol 395.4 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
rifampicin > 800 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
ritonavir 24.8 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Salicylic acid 304.3 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Simvastatin 76.5 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
sorafenib 0.5 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Sulindac > 200 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Tamoxifen 2.9 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Tolcapone 3.9 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Tolfenamic Acid 263.8 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Troglitazone 3.4 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Valproic Acid 267.2 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Zidovudine 416.1 µM 30 mins mouse liver mitochondria Rh123 fluorescence (excitation 485 nm, emission 535 nm) are recorded using a fluorescence multi-well plate reader (mCICCP (20 µM) treatments was considered as the 100% baseline for ΔΨm loss) decrease Positive EC20 36
Amiodarone 50 µM 1 hour Human HepG2 High-content screening assay Decrease Positive MEC 306
Amiodarone 5 µM 1 hour Human HepG2 High-content screening assay Increase Positive MEC 306
Chlorpromazine 100 µM 1 hour Human HepG2 High-content screening assay Decrease Positive MEC 306
Cyclosporin A 5 µM 1 hour Human HepG2 High-content screening assay Increase Positive MEC 306
imipramine 50 µM 1 hour Human HepG2 High-content screening assay Decrease Positive MEC 306
Maprotiline 5 µM 1 hour Human HepG2 High-content screening assay Decrease Positive MEC 306
Rotenone 5 µM 1 hour Human HepG2 High-content screening assay Decrease Positive MEC 306
Tamoxifen 100 µM 1 hour Human HepG2 High-content screening assay Decrease Positive MEC 306
Troglitazone 10 µM 1 hour Human HepG2 High-content screening assay Decrease Positive MEC 306
atorvastatin 100 µM 1 hour Human HepG2 High-content screening assay Increase Positive MEC 306
Cerivastatin 50 µM 1 hour Human HepG2 High-content screening assay Decrease Positive MEC 306
lovastatin 100 µM 1 hour Human HepG2 High-content screening assay Decrease Positive MEC 306
Simvastatin 50 µM 1 hour Human HepG2 High-content screening assay Decrease Positive MEC 306
tetracyclines decrease Positive 307

T181. Glycerol-3-phosphate dehydrogenase, mitochondrial