D0842 | chlorophacinone
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| MEMBRANE POTENTIAL | 0.64±0.25 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 3.55 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 4.65±4.78 | rat | hepatocytes | MMP assay | decrease | IC50 | 163 | |
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
   |
Danger |
H300: Fatal if swallowed [Danger Acute toxicity, oral] H310: Fatal in contact with skin [Danger Acute toxicity, dermal] H330: Fatal if inhaled [Danger Acute toxicity, inhalation] H360D: May damage the unborn child [Danger Reproductive toxicity] H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure] H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] |
P201, P202, P260, P262, P264, P270, P271, P273, P280, P281, P284, P301+P310, P302+P350, P304+P340, P308+P313, P310, P314, P320, P321, P322, P330, P361, P363, P391, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
|
|
Danger |
Aggregated GHS information provided by 128 companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. H300 (100%): Fatal if swallowed [Danger Acute toxicity, oral] H310 (100%): Fatal in contact with skin [Danger Acute toxicity, dermal] H330 (67.97%): Fatal if inhaled [Danger Acute toxicity, inhalation] H331 (32.03%): Toxic if inhaled [Danger Acute toxicity, inhalation] H360 (65.62%): May damage fertility or the unborn child [Danger Reproductive toxicity] H372 (100%): Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure] H400 (99.22%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410 (100%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P201, P202, P260, P261, P262, P264, P270, P271, P273, P280, P281, P284, P301+P310, P302+P350, P304+P340, P308+P313, P310, P311, P314, P320, P321, P322, P330, P361, P363, P391, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
|
|
Danger |
H300: Fatal if swallowed [Danger Acute toxicity, oral] H310: Fatal in contact with skin [Danger Acute toxicity, dermal] H330: Fatal if inhaled [Danger Acute toxicity, inhalation] H360D: May damage the unborn child [Danger Reproductive toxicity] H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure] H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] |
P201, P202, P260, P262, P264, P270, P271, P273, P280, P281, P284, P301+P310, P302+P350, P304+P340, P308+P313, P310, P314, P320, P321, P322, P330, P361, P363, P391, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
|
|
Danger |
H300: Fatal if swallowed [Danger Acute toxicity, oral] H310: Fatal in contact with skin [Danger Acute toxicity, dermal] H330: Fatal if inhaled [Danger Acute toxicity, inhalation] H360: May damage fertility or the unborn child [Danger Reproductive toxicity] H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure] H371: May cause damage to organs [Warning Specific target organ toxicity, single exposure] H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure] |
P201, P202, P260, P262, P264, P270, P271, P280, P281, P284, P301+P310, P302+P350, P304+P340, P307+P311, P308+P313, P309+P311, P310, P314, P320, P321, P322, P330, P361, P363, P403+P233, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| Organism | Test type | Route | Dose (normalized dose) | Effect | Source |
|---|---|---|---|---|---|
| bird - domestic | LD50 | oral | 430mg/kg (430mg/kg) | Guide to the Chemicals Used in Crop Protection. Vol. 6, Pg. 112, 1973. | |
| mouse | LD50 | oral | 1060ug/kg (1.06mg/kg) | Toxicology and Applied Pharmacology. Vol. 25, Pg. 42, 1973. | |
| mammal (species unspecified) | LD50 | oral | 7500ug/kg (7.5mg/kg) | Guide to the Chemicals Used in Crop Protection. Vol. 6, Pg. 112, 1973. | |
| rabbit | LD50 | oral | 50mg/kg (50mg/kg) | Guide to the Chemicals Used in Crop Protection. Vol. 6, Pg. 112, 1973. | |
| rat | LC50 | inhalation | > 3gm/m3/1H (3000mg/m3) | "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc of Chemistry, 1983-86Vol. A084, Pg. 1983, | |
| rabbit | LD50 | skin | 200mg/kg (200mg/kg) | Guide to the Chemicals Used in Crop Protection. Vol. 6, Pg. 112, 1973. | |
| rat | LD50 | oral | 2100ug/kg (2.1mg/kg) | Guide to the Chemicals Used in Crop Protection. Vol. 6, Pg. 112, 1973. | |
| women | TDLo | oral | 5mg/kg (5mg/kg) | vascular: other changes | Journal of Toxicology, Clinical Toxicology. Vol. 27, Pg. 79, 1989. |
| duck | LD50 | oral | 100mg/kg (100mg/kg) | Guide to the Chemicals Used in Crop Protection. Vol. 6, Pg. 112, 1973. | |
| ((4-Chlorphenyl)-1-phenyl)-acetyl-1,3-indandion | ((4-Chlorphenyl)-1-phenyl)-acetyl-1,3-indandion [German] | 1,3-Indandione, 2-((p-chlorophenyl)phenylacetyl)- |
| 1,3-Indandione, 2-[(p-chlorophenyl)phenylacetyl]- | 1-(4-Chlorphenyl)-1-phenyl-acetyl-indan-1,3-dion | 1-(4-Chlorphenyl)-1-phenyl-acetyl-indan-1,3-dion [German] |
| 1H-Indene-1,3(2H)-dione, 2-((4-chlorophenyl)phenylacetyl)- | 1H-Indene-1,3(2H)-dione, 2-[(4-chlorophenyl)phenylacetyl]- | 2(2-(4-Chloor-fenyl-2-fenyl)-acetyl)-indaan-1,3-dion |
| 2(2-(4-Chloor-fenyl-2-fenyl)-acetyl)-indaan-1,3-dion [Dutch] | 2(2-(4-Chlor-phenyl-2-phenyl)acetyl)indan-1,3-dion | 2(2-(4-Chlor-phenyl-2-phenyl)acetyl)indan-1,3-dion [German] |
| 2(2-(4-Chlor-phenyl-2-phenyl)acetyl)indan-1,3-dione | 2(2-(4-Chlorophenyl)-2-phenylacetyl)indan-1,3-dione | 2(2-(4-Cloro-fenil-2FENIL)-acetil)indan-1,3-dione [Italian] |
| 2(2-(4-Cloro-fenil-2fenil)-acetil)indan-1,3-dione | 2-((4-Chlorophenyl)phenylacetyl)-1H-indene-1,3(2H)-dione | 2-((p-Chlorophenyl)phenylacetyl)-1,3-indandione |
| 2-(2-(4-Chlorophenyl)-2-phenylacetyl)-1H-indene-1,3(2H)-dione; | 2-(2-(4-Chlorophenyl)-2-phenylacetyl)indane-1,3-dione | 2-(2-Phenyl-2-(4-chlorophenyl)acetyl)-1,3-indandione |
| 2-(alpha-p-Chlorophenyl-alpha-phenylacetyl)indane-1,3-dione | 2-(alpha-p-Chlorophenylacetyl)indane-1,3-dione | 2-[(4-Chlorophenyl)(phenyl)acetyl]-1H-indene-1,3(2H)-dione |
| 2-[(4-chlorophenyl)phenylacetyl]-1h-indene-1,3(2h)-dione | 2-[(p-Chlorophenyl)phenylacetyl]-1,3-indandione | 2-[2-(4-chlorophenyl)-1-oxo-2-phenylethyl]indene-1,3-dione |
| 2-[2-(4-chlorophenyl)-2-phenyl-ethanoyl]indene-1,3-dione | 2-[2-(4-chlorophenyl)-2-phenylacetyl]indene-1,3-dione | 3691-35-8 |
| 691C358 | A823450 | AC-19783 |
| ACM3691358 | AKOS015896099 | Actosin C |
| Afnor | BCP20502 | BRN 2063081 |
| Baraage | C18514 | C23H15ClO3 |
| CAID | CAS-3691-35-8 | CHEBI:81796 |
| CHEMBL1874081 | CHLOROPHACINONE | CTK8E3593 |
| Caswell No. 211C | Chloorfacinon | Chloorfacinon [Dutch] |
| Chlorfacinon | Chlorfacinon [German] | Chlorodiphacinone |
| Chlorophacinone [BSI:ISO] | Chlorophacinone, PESTANAL(R), analytical standard | Chlorophenacone |
| Chlorphacinon | Chlorphacinon [Italian] | Chlorphacinone |
| Chlorphenacone | DRAT | DSSTox_CID_12348 |
| DSSTox_GSID_32348 | DSSTox_RID_78919 | DTXSID2032348 |
| EINECS 223-003-0 | EPA Pesticide Chemical Code 067707 | FT-0655394 |
| HSDB 6432 | Indandione, 2-((p-chlorophenyl)phenylacetyl)- | Indene-1,3(2H)-dione, 2-((4-chlorophenyl)phenylacetyl)- |
| LM 91 | LS-81148 | Lepit |
| Liphadione | M174 | Microzul |
| Muriol | NCGC00163928-01 | NCGC00255247-01 |
| Orcomolebait | Partox | Q413488 |
| Ramucide | Ranac | Raticide-Caid |
| Ratindan 3 | Ratomet | Raviac |
| Razol | Redentin | Rozol |
| Rozol Prairie Dog Bait | SC-18654 | SCHEMBL18961 |
| Sakarat special | Saviac | Skaterpax |
| TR-015043 | Topitox | Tox21_301565 |
| UDHXJZHVNHGCEC-UHFFFAOYSA-N |