D1036 | p,p'-ddt
| Toxicity | Dose | Time | Species | Model | Method | Action | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| MEMBRANE POTENTIAL | 24.26±2.74 | human | qHTS-HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | 30.83 | human | HepG2 | MMP assay | decrease | IC50 | 163 | |
| MEMBRANE POTENTIAL | rat | hepatocytes | MMP assay | Negative | IC50 | 163 | ||
| APOPTOSIS | 30 μM | rat | Sertoli cells | induce | 242 | |||
| Pictogram | Signal | Statements | Precautionary Statement Codes |
|---|---|---|---|
   |
Danger |
H301: Toxic if swallowed [Danger Acute toxicity, oral] H351: Suspected of causing cancer [Warning Carcinogenicity] H372 **: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure] H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] |
P201, P202, P260, P264, P270, P273, P281, P301+P310, P308+P313, P314, P321, P330, P391, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
|
|
Danger |
Aggregated GHS information provided by 210 companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. H301+H311 (18.1%): Toxic if swallowed or in contact with skin [Danger Acute toxicity, oral acute toxicity, dermal] H301 (99.52%): Toxic if swallowed [Danger Acute toxicity, oral] H311 (20%): Toxic in contact with skin [Danger Acute toxicity, dermal] H351 (99.52%): Suspected of causing cancer [Warning Carcinogenicity] H372 (99.52%): Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure] H400 (100%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410 (99.52%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. |
P201, P202, P260, P264, P270, P273, P280, P281, P301+P310, P302+P352, P308+P313, P312, P314, P321, P322, P330, P361, P363, P391, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
|
|
Danger |
H301: Toxic if swallowed [Danger Acute toxicity, oral] H351: Suspected of causing cancer [Warning Carcinogenicity] H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure] H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] |
P201, P202, P260, P264, P270, P273, P281, P301+P310, P308+P313, P314, P321, P330, P391, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
|
|
Danger |
H301: Toxic if swallowed [Danger Acute toxicity, oral] H311: Toxic in contact with skin [Danger Acute toxicity, dermal] H320: Causes eye irritation [Warning Serious eye damage/eye irritation] H340: May cause genetic defects [Danger Germ cell mutagenicity] H350: May cause cancer [Danger Carcinogenicity] H360: May damage fertility or the unborn child [Danger Reproductive toxicity] H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure] H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure] H373: Causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure] H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] |
P201, P202, P260, P264, P270, P273, P280, P281, P301+P310, P302+P352, P305+P351+P338, P307+P311, P308+P313, P312, P314, P321, P322, P330, P337+P313, P361, P363, P391, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
 |
Danger |
H302: Harmful if swallowed [Warning Acute toxicity, oral] H311: Toxic in contact with skin [Danger Acute toxicity, dermal] H315: Causes skin irritation [Warning Skin corrosion/irritation] H320: Causes eye irritation [Warning Serious eye damage/eye irritation] H340: May cause genetic defects [Danger Germ cell mutagenicity] H351: Suspected of causing cancer [Warning Carcinogenicity] H361: Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity] H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure] H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure] |
P201, P202, P260, P264, P270, P280, P281, P301+P312, P302+P352, P305+P351+P338, P307+P311, P308+P313, P312, P314, P321, P322, P330, P332+P313, P337+P313, P361, P362, P363, P405, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
|
|
Warning |
H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] |
P273, P391, and P501; (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| Organism | Test type | Route | Dose (normalized dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | oral | 135mg/kg (135mg/kg) | Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 12, Pg. 368, 1953. | |
| dog | LD50 | oral | 150mg/kg (150mg/kg) | Yakkyoku. Pharmacy. Vol. 32, Pg. 463, 1981. | |
| rat | LD50 | skin | 1931mg/kg (1931mg/kg) | Special Publication of the Entomological Society of America. Vol. 78-1, Pg. 14, 1978. | |
| rat | LD50 | unreported | 300mg/kg (300mg/kg) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 37(10), Pg. 27, 1972. | |
| monkey | LD50 | oral | 200mg/kg (200mg/kg) | Advances in Pharmacology and Chemotherapy. Vol. 12, Pg. 31, 1975. | |
| rat | LD50 | subcutaneous | 1500mg/kg (1500mg/kg) | British Medical Journal. Vol. 1, Pg. 865, 1945. | |
| guinea pig | LD50 | skin | 1gm/kg (1000mg/kg) | British Medical Journal. Vol. 1, Pg. 865, 1945. | |
| human | TDLo | oral | 5mg/kg (5mg/kg) | Pharmazie. Vol. 2, Pg. 268, 1947. | |
| mammal (species unspecified) | LD50 | unreported | 200mg/kg (200mg/kg) | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 17(3), Pg. 32, 1973. | |
| rabbit | LD50 | subcutaneous | 250mg/kg (250mg/kg) | British Medical Journal. Vol. 1, Pg. 865, 1945. | |
| cat | LDLo | intravenous | 40mg/kg (40mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 86, Pg. 213, 1946. | |
| man | TDLo | oral | 6mg/kg (6mg/kg) | "Clinical Memoranda on Economic Poisons," U.S. Dept. HEW, Public Health Service, Communicable Disease Center, Atlanta, GA, 1956Vol. -, Pg. 1, 1956. | |
| human | TDLo | oral | 16mg/kg (16mg/kg) | behavioral: convulsions or effect on seizure threshold | "Clinical Memoranda on Economic Poisons," U.S. Dept. HEW, Public Health Service, Communicable Disease Center, Atlanta, GA, 1956Vol. -, Pg. 1, 1956. |
| human | LDLo | oral | 500mg/kg (500mg/kg) | "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989Vol. 11, Pg. 446, 1989. | |
| rat | LD50 | intraperitoneal | 9100ug/kg (9.1mg/kg) | Proceedings of the European Society of Toxicology. Vol. 17, Pg. 351, 1976. | |
| infant | LDLo | oral | 150mg/kg (150mg/kg) | lungs, thorax, or respiration: acute pulmonary edema | British Medical Journal. Vol. 2, Pg. 845, 1945. |
| frog | LD50 | oral | 7600ug/kg (7.6mg/kg) | Environmental Pollution. Vol. 20, Pg. 45, 1979. | |
| monkey | LDLo | intravenous | 50mg/kg (50mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 86, Pg. 213, 1946. | |
| man | LDLo | unreported | 221mg/kg (221mg/kg) | "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970Vol. 2, Pg. 73, 1970. | |
| chicken | LDLo | oral | 300mg/kg (300mg/kg) | Medizinische Monatsschrift. Vol. 4, Pg. 25, 1950. | |
| rabbit | LD50 | skin | 300mg/kg (300mg/kg) | British Medical Journal. Vol. 1, Pg. 865, 1945. | |
| frog | LD50 | parenteral | 24100ug/kg (24.1mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 74, Pg. 343, 1947. | |
| hamster | LD50 | oral | > 5gm/kg (5000mg/kg) | Laboratory Animal Science. Vol. 26, Pg. 274, 1976. | |
| guinea pig | LD50 | subcutaneous | 900mg/kg (900mg/kg) | British Medical Journal. Vol. 1, Pg. 865, 1945. | |
| rabbit | LD50 | oral | 250mg/kg (250mg/kg) | Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 347, 1966. | |
| domestic animals - goat/sheep | LDLo | oral | 300mg/kg (300mg/kg) | Medizinische Monatsschrift. Vol. 4, Pg. 25, 1950. | |
| cat | LDLo | oral | 250mg/kg (250mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 86, Pg. 213, 1946. | |
| guinea pig | LD50 | oral | 150mg/kg (150mg/kg) | European Journal of Toxicology and Environmental Hygiene. Vol. 7, Pg. 159, 1974. | |
| mouse | LD50 | intraperitoneal | 32mg/kg (32mg/kg) | Proceedings of the European Society of Toxicology. Vol. 17, Pg. 351, 1976. | |
| rabbit | LDLo | intravenous | 50mg/kg (50mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 86, Pg. 213, 1946. | |
| rat | LD50 | oral | 87mg/kg (87mg/kg) | Down to Earth. Vol. 35, Pg. 25, 1979. | |
| dog | LDLo | intravenous | 75mg/kg (75mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 86, Pg. 213, 1946. | |
| .alpha.,.alpha.-Bis(p-chlorophenyl)-.beta.,.beta.,.beta.-trichlorethane | .alpha.,.beta.,.beta.-trichlorethane | 1,1'-(2,2,2,-Trichloroethylidene)bis[4-chlorobenzene] |
| 1,1'-(2,2,2-Trichloroethylidene)bis(4-chloro)-Benzene | 1,1'-(2,2,2-Trichloroethylidene)bis(4-chlorobenzene) | 1,1'-(2,2,2-Trichloroethylidene)bis(4-chlorobenzene), 9CI |
| 1,1'-(2,2,2-trichloroethane-1,1-diyl)bis(4-chlorobenzene) | 1,1'-(2,2,2-trichloroethylidene)bis[4-chlorobenzene] | 1,1,1-TRICHLORO-2,2-BIS(PARA-CHLOROPHNYL)ETHANE |
| 1,1,1-Trichloor-2,2-bis(4-chloor fenyl)-ethaan | 1,1,1-Trichloor-2,2-bis(4-chloor fenyl)-ethaan [Dutch] | 1,1,1-Trichlor-2,2-bis(4-chlor-phenyl)-aethan |
| 1,1,1-Trichlor-2,2-bis(4-chlor-phenyl)-aethan [German] | 1,1,1-Trichloro-2,2-bis(4,4'-dichlorodiphenyl)ethane | 1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethane |
| 1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethane solution | 1,1,1-Trichloro-2,2-bis(p-chlorophenyl)ethane | 1,1,1-Trichloro-2,2-bis-(4'-chlorophenyl)ethane |
| 1,1,1-Trichloro-2,2-bis-(4'-chlorophenyl)ethane (DDT) | 1,1,1-Trichloro-2,2-di(4-chlorophenyl)-ethane | 1,1,1-Trichloro-2,2-di(4-chlorophenyl)ethane |
| 1,1,1-Trichlorobis(chlorophenyl)ethane | 1,1,1-Tricloro-2,2-bis(4-cloro-fenil)-etano | 1,1,1-Tricloro-2,2-bis(4-cloro-fenil)-etano [Italian] |
| 1,1,1-Tricloro-2,2-bis(4-cloro-fenyl)-etano | 1,1,1-Tricloro-2,2-bis(4-cloro-fenyl)-etano [Italian] | 1,1,1-trichloro-2,2-bis(4-chlorophenyl)-ethane |
| 1,1,1-trichloro-2,2-bis(p-chlorophenyl)-ethane | 1,1,1-trichloro-2-2-bis(4-chlorophenyl)ethane | 1,1-Bis(4-chlorophenyl)-2,2,2-trichloroethane |
| 1,1-Bis(p-chlorophenyl)-2,2,2-trichloroethane | 1,1-Bis-(p-chlorophenyl)-2,2,2-trichloroethane | 1,1-Trichloor-2,2-bis(4-chloor fenyl)-ethaan |
| 1,1-Trichlor-2,2-bis(4-chlor-phenyl)-aethan | 1,1-Trichloro-2,2-bis(4,4'-dichlorodiphenyl)ethane | 1,1-Trichloro-2,2-bis(p-chlorophenyl)ethane |
| 1,1-Trichloro-2,2-bis(p-chlorophenyl)ethane chlorophenothane | 1,1-Trichloro-2,2-di(4-chlorophenyl)ethane | 1,1-Tricloro-2,2-bis(4-cloro-fenil)-etano |
| 1,1-bis(p-Chlorophenyl)-2,2,2-trichIoroethane | 1-Chloranyl-4-[2,2,2-Tris(Chloranyl)-1-(4-Chlorophenyl)ethyl]benzene | 1-Chloro-4-[2,2,2-trichloro-1-(4-chlorophenyl)ethyl]benzene |
| 1-Chloro-4-[2,2,2-trichloro-1-(4-chlorophenyl)ethyl]benzene # | 2,2,2-Trichloro-1,1-bis(4-chlorophenyl)ethane | 2,2,2-Trichloro-1,1-bis(p-chlorophenyl)-Ethane |
| 2,2,2-trichlorobis(4-chloroph enyl)ethane | 2,2,2-trichlorobis(4-chlorophenyl)ethane | 2,2-Bis(p-chlorophenyl)-1,1,1-trichloroethane |
| 4,4'-(2,2,2-Trichloroethane-1,1-diyl)bis(chlorobenzene) | 4,4'-DDT | 4,4'-DDT (1,1,1-Trichloro-2,2-bis(p-chlorophenyl)ethane) |
| 4,4'-DDT 10 microg/mL in Cyclohexane | 4,4'-DDT 100 microg/mL in Cyclohexane | 4,4'-DDT 1000 microg/mL in Toluene |
| 4,4'-DDT 5000 microg/mL in Methanol | 4,4'-DDT solution | 4,4'-DDT solution 100 ng/muL in methanol |
| 4,4'-DDT solution, 100 ng/muL in methanol, PESTANAL(R), analytical standard | 4,4'-DDT solution, 200 mug/mL in isooctane, analytical standard | 4,4'-DDT solution, certified reference material, 5000 mug/mL in methanol |
| 4,4'-DDT, 98% | 4,4'-DDT, PESTANAL(R), analytical standard | 4,4'-DDT, certified reference material, TraceCERT(R) |
| 4,4'-Dichlorodiphenyltrichloroethane | 4,4-DDT | 4,4|A-DDT |
| 4-chloro-1-[2,2,2-trichloro-1-(4-chlorophenyl)ethyl]benzene | 50-29-3 | 6WT |
| AC-12071 | ACM50293 | AI3-01506 |
| AKOS003235691 | Aavero-extra | Agritan |
| Anofex | Arkotine | Azotox |
| Azotox M 33 | Azotox M-33 | BDBM50410508 |
| BIDD:ER0496 | BIDD:PXR0066 | BRD-K51799616-001-02-2 |
| BRN 1882657 | BSPBio_002477 | Benzene, 1,1'(2,2,2-trichloroethylidene)bis[4-chloro- |
| Benzene, 1,1'-(2,2,2-trichloroethylidene)bis(4-chloro- | Benzene, 1,1'-(2,2,2-trichloroethylidene)bis[4-chloro- | Benzene,1'-(2,2,2-trichloroethylidene)bis[4-chloro- |
| Benzochloryl | Bis(p-chlorophenyl)-2,2,2-trichloroetha ne | Bis(p-chlorophenyl)-2,2,2-trichloroethane |
| Bosan Supra | Bovidermol | C-20741 |
| C04623 | CAS-50-29-3 | CC-25919 |
| CCG-39114 | CCRIS 194 | CHEBI:16130 |
| CHEMBL416898 | CIW5S16655 | Caswell No. 308 |
| Chlofenotan | Chlorophenothan | Chlorophenothane |
| Chlorophenothane [NF] | Chlorophenothanum | Chlorophenothanum technicum |
| Chlorophenotoxum | Chlorphenotane | Chlorphenothan |
| Chlorphenotoxum | Citox | Clofenotan |
| Clofenotane | Clofenotane (INN) | Clofenotane [INN] |
| Clofenotane technique | Clofenotano | Clofenotano [INN-Spanish] |
| Clofenotanum | Clofenotanum [INN-Latin] | D.D.T. technique |
| D07367 | DB-051751 | DB13424 |
| DDT | DDT 50 WP | DDT [BSI:ISO] |
| DDT and metabolites | DDT(p,p') | DDT, p,p'- |
| DSSTox_CID_375 | DSSTox_GSID_20375 | DSSTox_RID_75551 |
| DTXSID4020375 | Dedelo | Deoval |
| Detox | Detox (pesticide) | Detoxan |
| Dibovan | Dibovin | Dichlorodiphenyltrichloroethane (DDT) |
| Dichlorojiphinyltrichloroethane | Dicophane | Dicophane, BAN |
| Dicophaner | Didigam | Didimac |
| DivK1c_006654 | Dodat | Dykol |
| EINECS 200-024-3 | ENT 1,506 | ENT-1506 |
| EPA Pesticide Chemical Code 029201 | Estonate | Ethane, 1,1,1-trichloro-2,2-bis(4-chlorophenyl)- |
| Ethane, 1,1,1-trichloro-2,2-bis(p-chlorophenyl)- | Ethane,1,1-trichloro-2,2-bis(4-chlorophenyl)- | Ethane,1,1-trichloro-2,2-bis(p-chlorophenyl)- |
| FT-0603206 | Genitox | Gesafid |
| Gesapon | Gesarex | Gesarol |
| Geusapon | Guesapon | Guesarol |
| Gyron | HSDB 200 | Havero-extra |
| Hildit | InChI=1/C14H9Cl5/c15-11-5-1-9(2-6-11)13(14(17,18)19)10-3-7-12(16)8-4-10/h1-8,13; | Ivoran |
| Ixodex | KBio1_001598 | KBio2_002462 |
| KBio2_005030 | KBio2_007598 | KBio3_001977 |
| KBioGR_001197 | KBioSS_002469 | Klorfenoton |
| Klorfenoton [Swedish Pharmacopoeia] | Kopsol | LS-138 |
| MCULE-1446144401 | MFCD00000802 | Micro ddt 75 |
| Mutoxan | Mutoxin | NCGC00091071-01 |
| NCGC00091071-02 | NCGC00091071-03 | NCGC00091071-04 |
| NCGC00091071-05 | NCGC00091071-06 | NCGC00091071-07 |
| NCGC00091071-08 | NCGC00254176-01 | NCGC00259046-01 |
| NCI-C00464 | NSC 8939 | NSC-8939 |
| NSC8939 | Neocid | Neocid (VAN) |
| Neocidol (solid) | Neocidol, solid | OMS 0016 |
| OMS 0016 [French] | OMS 16 | PEB1 |
| Parachlorocidum | Pentachlorin | Pentech |
| Penticide | Penticidum | Ppzeidan |
| Q163648 | R50 | RCRA waste no. U061 |
| Rcra waste number U061 | Rukseam | SBB061567 |
| SCHEMBL7181 | SPBio_001106 | SPECTRUM330070 |
| SR-01000883717 | SR-01000883717-1 | ST51047572 |
| Santobane | SpecPlus_000558 | Spectrum2_001233 |
| Spectrum3_000859 | Spectrum4_000699 | Spectrum5_002036 |
| Spectrum_001927 | T0379 | TR-017982 |
| Tafidex | Tech ddt | Tox21_111076 |
| Tox21_111076_1 | Tox21_201495 | Tox21_300067 |
| Trichloro-2,2-bis(p-chlorophenyl)ethane | Trichlorobis(4'-chlorophenyl)ethane | Trichlorobis(4-chlorophenyl)ethane |
| UNII-CIW5S16655 | WLN: GXGGYR DG&R DG | YVGGHNCTFXOJCH-UHFFFAOYSA-N |
| ZINC1530011 | Zeidane | Zerdane |
| alpha,alpha-Bis(p-chlorophenyl)-beta,beta,beta-trichlorethane | alpha,alpha-Bis(p-chlorophenyl)-beta,beta,beta-trichloroethane | bmse000634 |
| dichlorodiphenyltrichloroethane | micro ddt 75 | p'-Zeidane |
| p'-Zeidane [France] | p,p'-DDT | p,p'-DDT 100 microg/mL in Methanol |
| p,p'-DDT, BSI | p,p'-DDT~p,p' -Dichloro-1,1-diphenyl-2,2,2-trichloroethane | p,p'-DDT~p,p'-Dichloro-1,1-diphenyl-2,2,2-trichloroethane |
| p,p'-Dichlorodiphenyltrichloroethane | p,p'-Dichlorodiphenyltrichloroethane (DDT) | p,p'-Dichlorodiphenyltrichloromethylmethane |
| p,p-DDT | para,para'-DDT | pe ntech |